GUARDANT HEALTH INC GH
COM · Common Stock · CUSIP 40131M109 · ISIN US40131M1099
American biotechnology company
- SectorHealth care
- IndustryServices-Medical Laboratories
- HeadquartersPalo Alto, CA
- Founded2012
- Websiteguardanthealth.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.7m this quarter). Holder counts are more reliable. Shares outstanding: 102.4m as of 2022-10-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $27.20. Options: 25 managers hold calls ($110.9m notional), 16 hold puts ($21.6m).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 329 |
| Q4 2022 | 293 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $207.2m | $135.6m | 0.65 |
| Q4 2022 | $110.9m | $21.6m | 0.19 |
Biggest buyers
| ALLIANCEBERNSTEIN L.P. | Added | +1.8m |
| Capital International Investors | Added | +1.7m |
| Balyasny Asset Management L.P. | Added | +799.7k |
| MILLENNIUM MANAGEMENT LLC | New | +594.6k |
| FEDERATED HERMES, INC. | Added | +444.5k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | Added | +430.3k |
| Qube Research & Technologies Ltd | Added | +342.5k |
| TWINBEECH CAPITAL LP | New | +308.9k |
| TWO SIGMA INVESTMENTS, LP | Added | +307.8k |
| CREDIT SUISSE AG/ | Added | +301.9k |
Biggest sellers
| Holocene Advisors, LP | Sold out | -1.3m |
| FRANKLIN RESOURCES INC | Reduced | -1.3m |
| ORBIMED ADVISORS LLC | Sold out | -992.4k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Sold out | -991.6k |
| JPMORGAN CHASE & CO | Reduced | -812.6k |
| WESTFIELD CAPITAL MANAGEMENT CO LP | Sold out | -581.6k |
| Clearbridge Investments, LLC | Reduced | -523.2k |
| Iron Triangle Partners LP | Sold out | -487.2k |
| Sculptor Capital LP | Sold out | -482.6k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Sold out | -400.0k |
Biggest calls
| JPMORGAN CHASE & CO | Added | $27.9m1.0m shares |
| Holocene Advisors, LP | Unchanged | $18.9m693.2k shares |
| PURA VIDA INVESTMENTS, LLC | Reduced | $11.1m408.9k shares |
| GROUP ONE TRADING LLC | Added | $9.3m340.9k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $9.3m340.7k shares |
| JANE STREET GROUP, LLC | Added | $6.3m233.4k shares |
| SIMPLEX TRADING, LLC | Added | $5.9m217.0k shares |
| CITADEL ADVISORS LLC | Reduced | $5.7m208.3k shares |
| Segantii Capital Management Ltd | New | $5.0m2.0k shares |
| Granite Point Capital Management, L.P. | New | $2.7m100.0k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $5.1m188.2k shares |
| CITADEL ADVISORS LLC | Reduced | $5.0m183.0k shares |
| JANE STREET GROUP, LLC | Added | $4.7m174.6k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.1m77.6k shares |
| GROUP ONE TRADING LLC | Reduced | $1.0m38.0k shares |
| JPMORGAN CHASE & CO | Reduced | $998.0k36.7k shares |
| Portman Square Capital LLP | First filing | $843.2k31.0k shares |
| Walleye Capital LLC | Added | $476.0k17.5k shares |
| Point72 Asset Management, L.P. | New | $340.0k12.5k shares |
| WOLVERINE ASSET MANAGEMENT LLC | Reduced | $282.9k10.4k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution -2.3 pts · filed 2026-07-28 | 5.2% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-30 | 5.0% |
Fell to 5% or below in the last year: PRICE T ROWE ASSOCIATES INC /MD/ (4.9%, 2026-08-14), VANGUARD GROUP INC (0.0%, 2026-03-27; now reported by VANGUARD CAPITAL MANAGEMENT LLC)
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 2 | $17.7m | 1 | $1.5m | — |
| Q1 2022 | 0 | — | 1 | $1.1m | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 2 | $587.4k | — |
| Q4 2022 | 0 | — | 1 | $162.1k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-11-15 | Kalia Kumud Chief Information Officer | Sold | $162.1k3.1k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.04% of their portfolio | 15.3m $416.3m | Added +72.6k |
| VANGUARD GROUP INC 0.01% of their portfolio | 9.0m $245.9m | Added +124.7k |
| Capital International Investors 0.06% of their portfolio | 7.9m $213.6m | Added +1.7m |
| BlackRock Inc. 0.00% of their portfolio | 5.5m $149.5m | Added +227.3k |
| MORGAN STANLEY 0.02% of their portfolio | 5.2m $141.9m | Added +222.8k |
| VIKING GLOBAL INVESTORS LP 0.56% of their portfolio | 4.1m $111.7m | Added +272.0k |
| Clearbridge Investments, LLC 0.07% of their portfolio | 2.6m $70.4m | Reduced -523.2k |
| ALLIANCEBERNSTEIN L.P. 0.03% of their portfolio | 2.5m $68.4m | Added +1.8m |
| CREDIT SUISSE AG/ 0.06% of their portfolio | 2.1m $57.4m | Added +301.9k |
| Capital Research Global Investors 0.02% of their portfolio | 2.0m $54.4m | Reduced -148.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio | 1.7m $46.3m | Added +108.4k |
| FRANKLIN RESOURCES INC 0.02% of their portfolio | 1.7m $46.2m | Reduced -1.3m |
| EVENTIDE ASSET MANAGEMENT, LLC 0.90% of their portfolio | 1.7m $45.7m | Unchanged |
| Temasek Holdings (Private) Ltd 0.26% of their portfolio | 1.6m $44.1m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 1.5m $40.5m | Reduced -16.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 1.4m $38.6m | Added +75.5k |
| VOYA INVESTMENT MANAGEMENT LLC 0.04% of their portfolio | 1.4m $37.3m | Added +57.2k |
| Balyasny Asset Management L.P. 0.11% of their portfolio | 1.1m $30.0m | Added +799.7k |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 877.0k $23.9m | Reduced -268.7k |
| Invesco Ltd. 0.01% of their portfolio | 870.0k $23.7m | Added +242.2k |
| Blue Water Life Science Advisors, LP 15.87% of their portfolio | 868.4k $23.6m | Reduced -110.0k |
| NORGES BANK 0.01% of their portfolio | 787.0k $21.4m | Added +3.2k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 690.9k $18.8m | Reduced -288.3k |
| Aristotle Atlantic Partners, LLC 0.94% of their portfolio | 618.8k $16.8m | Added +237.6k |
| PICTET ASSET MANAGEMENT SA 0.02% of their portfolio | 609.0k $16.6m | Reduced -74.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio | 600.5k $16.3m | Added +23.7k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 594.6k $16.2m | New |
| Fiera Capital Corp 0.05% of their portfolio | 547.5k $14.9m | Reduced -24.4k |
| ARK Investment Management LLC 0.12% of their portfolio | 500.1k $13.6m | Reduced -42.0k |
| FEDERATED HERMES, INC. 0.04% of their portfolio | 495.1k $13.5m | Added +444.5k |
| TWO SIGMA INVESTMENTS, LP 0.04% of their portfolio | 487.4k $13.3m | Added +307.8k |
| Erste Asset Management GmbH 0.28% of their portfolio | 482.6k $13.1m | Added +170.0k |
| Nuveen Asset Management, LLC 0.01% of their portfolio | 481.2k $13.1m | Reduced -45.2k |
| Integral Health Asset Management, LLC 2.91% of their portfolio | 475.0k $12.9m | Added +25.0k |
| Tekla Capital Management LLC 0.49% of their portfolio | 472.2k $12.8m | Added +126.1k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.07% of their portfolio | 460.9k $12.5m | Added +430.3k |
| Candriam S.C.A. 0.08% of their portfolio | 459.6k $12.5m | Added +270.6k |
| RTW INVESTMENTS, LP 0.24% of their portfolio | 430.9k $11.7m | Reduced -295.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 427.6k $11.6m | Added +1.8k |
| PURA VIDA INVESTMENTS, LLC 1.95% of their portfolio | 426.9k $11.6m | Added +25.9k |
| Railway Pension Investments Ltd 0.10% of their portfolio | 379.1k $10.3m | Unchanged |
| Qube Research & Technologies Ltd 0.06% of their portfolio | 374.2k $10.2m | Added +342.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 369.1k $10.0m | Reduced -19.9k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.01% of their portfolio | 328.7k $8.9m | Added +4.5k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 326.3k $8.9m | Reduced -62.7k |
| TWINBEECH CAPITAL LP 0.16% of their portfolio | 308.9k $8.4m | New |
| Cubist Systematic Strategies, LLC 0.07% of their portfolio | 297.1k $8.1m | Added +287.2k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 284.5k $7.7m | Added +146.8k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 283.6k $7.7m | Reduced -68.2k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.01% of their portfolio | 241.8k $6.6m | Reduced -3.4k |
| BAMCO INC /NY/ 0.02% of their portfolio | 237.7k $6.5m | Reduced -346.3k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 236.6k $6.4m | Reduced -13.3k |
| Swiss National Bank 0.00% of their portfolio | 222.1k $6.0m | Added +4.6k |
| First Light Asset Management, LLC 0.52% of their portfolio | 204.8k $5.6m | New |
| PRIMECAP MANAGEMENT CO/CA/ 0.01% of their portfolio | 202.0k $5.5m | Reduced -27.0k |
| Rock Springs Capital Management LP 0.13% of their portfolio | 200.0k $5.4m | Unchanged |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 192.5k $5.2m | Added +57.3k |
| California Public Employees Retirement System 0.00% of their portfolio | 188.1k $5.1m | Reduced -12.5k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 185.1k $5.0m | Reduced -812.6k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 176.3k $4.8m | Added +122.8k |
| TUDOR INVESTMENT CORP ET AL 0.11% of their portfolio | 164.9k $4.5m | New |
| Granite Investment Partners, LLC 0.18% of their portfolio | 163.6k $4.4m | Added +23.0k |
| LAZARD ASSET MANAGEMENT LLC 0.01% of their portfolio | 154.1k $4.2m | Reduced -64.2k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 149.2k $4.1m | Added +104.7k |
| Eversept Partners, LP 0.38% of their portfolio | 146.1k $4.0m | Reduced -25.4k |
| BARCLAYS PLC 0.00% of their portfolio | 144.3k $3.9m | First filing |
| AXA S.A. 0.01% of their portfolio | 138.7k $3.8m | Reduced -366.8k |
| Bellevue Group AG 0.05% of their portfolio | 135.5k $3.7m | Added +73.4k |
| Schonfeld Strategic Advisors LLC 0.03% of their portfolio | 134.2k $3.7m | Added +33.1k |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 131.5k $3.6m | Reduced -19.9k |
| Tri Locum Partners LP 1.57% of their portfolio | 130.4k $3.5m | Reduced -155.5k |
| Bridgewater Associates, LP 0.02% of their portfolio | 128.5k $3.5m | Reduced -30.9k |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 122.9k $3.3m | New |
| CAPITAL FUND MANAGEMENT S.A. 0.07% of their portfolio | 121.8k $3.3m | New |
| Legal & General Group Plc 0.00% of their portfolio | 119.4k $3.2m | Reduced -4.0k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.01% of their portfolio | 119.2k $3.2m | Added +1.5k |
| GUGGENHEIM CAPITAL LLC 0.03% of their portfolio | 116.8k $3.2m | Added +644 |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 116.5k $3.2m | Reduced -5.5k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.01% of their portfolio | 114.1k $3.1m | Reduced -4.8k |
| Handelsbanken Fonder AB 0.02% of their portfolio | 112.8k $3.1m | Added +100 |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 110.3k $3.0m | Added +4.1k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 106.4k $2.9m | Reduced -14.5k |
| Rathbones Group PLC 0.03% of their portfolio | 98.5k $2.7m | Reduced -7.6k |
| Sicart Associates LLC 0.94% of their portfolio | 98.0k $2.7m | Reduced -38.5k |
| TD Asset Management Inc 0.00% of their portfolio | 96.1k $2.6m | Added +8.8k |
| Lombard Odier Asset Management (Switzerland) SA 0.20% of their portfolio | 93.5k $2.5m | Added +73.5k |
| Prescott Group Capital Management, L.L.C. 0.53% of their portfolio | 90.0k $2.4m | New |
| PDT Partners, LLC 0.38% of their portfolio | 86.2k $2.3m | New |
| SEVEN EIGHT CAPITAL, LP 0.61% of their portfolio | 85.5k $2.3m | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 85.3k $2.3m | Reduced -66.2k |
| VAN ECK ASSOCIATES CORP 0.01% of their portfolio | 85.2k $2.3m | Added +13.0k |
| Adalta Capital Management LLC 1.61% of their portfolio | 83.8k $2.3m | Reduced -18.6k |
| Sumitomo Mitsui Trust Group, Inc. 0.00% of their portfolio | 78.3k $2.1m | Reduced -5.9k |
| Amova Asset Management Americas, Inc. 0.03% of their portfolio | 78.3k $2.1m | Reduced -5.9k |
| Engineers Gate Manager LP 0.13% of their portfolio | 78.1k $2.1m | New |
| Citizens Business Bank 0.48% of their portfolio | 77.3k $2.1m | Added +20.7k |
| EULAV Asset Management 0.09% of their portfolio | 75.0k $2.0m | New |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC 0.63% of their portfolio | 74.5k $2.0m | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 68.9k $1.9m | New |
| LPL Financial LLC 0.00% of their portfolio | 68.1k $1.9m | Added +5.1k |