Vault-13

GENERATE BIOMEDICINES INC GENB

COM SHS · Common Stock · CUSIP 370920100

57 institutional holders
92,784,03892.8m shares reported held*
72.4% of all shares outstanding*
$1.2bnreported value*

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($499.5k this quarter). Holder counts are more reliable. Shares outstanding: 128.2m as of 2026-04-29, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $12.47. Options: 1 managers hold calls ($157.1k notional), 0 hold puts (—).

Trends to Q1 2026

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$50k$100k$150k$200kQ2 25 calls: $0Q2 25 puts: $0Q2 25P/C —Q3 25 calls: $0Q3 25 puts: $0Q3 25P/C —Q4 25 calls: $0Q4 25 puts: $0Q4 25P/C —Q1 26 calls: $157.1kQ1 26 puts: $0Q1 26P/C 0.00
Numbers
QuarterCallsPutsP/C
Q2 2025$0$0—
Q3 2025$0$0—
Q4 2025$0$0—
Q1 2026$157.1k$00.00

Biggest buyers

Flagship Pioneering, LLC New +62,673,117+62.7m
FMR LLC New +4,217,524+4.2m
Capital World Investors New +4,004,149+4.0m
BRAIDWELL LP New +3,592,999+3.6m
JPMORGAN CHASE & CO New +2,947,259+2.9m
PRICE T ROWE ASSOCIATES INC /MD/ New +2,109,633+2.1m
ARCH Venture Management, LLC New +1,944,426+1.9m
HarbourVest Partners LLC New +1,722,210+1.7m
BAKER BROS. ADVISORS LP New +1,423,602+1.4m
HARVARD MANAGEMENT CO INC New +1,111,100+1.1m

Biggest sellers

None

Biggest calls

Brevan Howard Capital Management LP New $157.1k12.6k shares

Biggest puts

None

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Flagship Pioneering, LLC 13G · exempt (held before listing) new · filed 2026-05-15 48.9% new 62.7m≈ $1.1bn 2026-05-15
Nally Michael 13G · exempt (held before listing) new · filed 2026-05-15 5.2% new 6.9m≈ $116.7m 2026-05-15

Insider purchases and sales in Q1 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
505Q2 24: 0 buyingQ2 24: 0 sellingQ3 24: 0 buyingQ3 24: 0 sellingQ3 24Q4 24: 0 buyingQ4 24: 0 sellingQ1 25: 0 buyingQ1 25: 0 sellingQ1 25Q2 25: 0 buyingQ2 25: 0 sellingQ3 25: 0 buyingQ3 25: 0 sellingQ3 25Q4 25: 0 buyingQ4 25: 0 sellingQ1 26: 5 buyingQ1 26: 0 sellingQ1 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q2 20240—0——
Q3 20240—0——
Q4 20240—0——
Q1 20250—0——
Q2 20250—0——
Q3 20250—0——
Q4 20250—0——
Q1 20265$75.3m0——
DateInsiderTradeSharesPrice ValueTheir holding
2026-03-04 Nally Michael Chief Executive Officer, director Bought 20,000 $12.00 $240.0k20.0k shares +4%
2026-03-02 AFEYAN NOUBAR +6 Director · By FPN II, L.P. Bought 1,562,500 $16.00 $25.0m1.6m shares +56%
2026-03-02 AFEYAN NOUBAR +6 Director · By Flagship Pioneering Fund VII, L.P. Bought 1,562,500 $16.00 $25.0m1.6m shares +11%
2026-03-02 AFEYAN NOUBAR +6 Director · By Pioneering Medicines 02, LLC Bought 1,562,500 $16.00 $25.0m1.6m shares new
2026-03-02 AFEYAN NOUBAR +7 Director · By FPN II, L.P. Bought 1,562,500 $16.00 $25.0m1.6m shares +56%
2026-03-02 AFEYAN NOUBAR +7 Director · By Flagship Pioneering Fund VII, L.P. Bought 1,562,500 $16.00 $25.0m1.6m shares +11%
2026-03-02 AFEYAN NOUBAR +7 Director · By Pioneering Medicines 02, LLC Bought 1,562,500 $16.00 $25.0m1.6m shares new
2026-03-02 Mendillo Jane L Director Bought 1,500 $16.00 $24.0k1.5k shares new
2026-03-02 Silvers Jason President & CFO · By daughter Bought 1,000 $16.00 $16.0k1.0k shares new
2026-03-02 Silvers Jason President & CFO · By son Bought 1,000 $16.00 $16.0k1.0k shares new
2026-03-02 Grous Beth Chief People Officer · By Spouse Bought 300 $16.00 $4.8k300 shares new

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q1 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Flagship Pioneering, LLC 67.44% of their portfolio CAMBRIDGE, MA 62,673,11762.7m $783.4m $783.4m 67.44% New
2 FMR LLC 0.00% of their portfolio BOSTON, MA 4,217,5244.2m $52.7m $52.7m 0.00% New
3 Capital World Investors 0.01% of their portfolio LOS ANGELES, CA 4,004,1494.0m $50.1m $50.1m 0.01% New
4 BRAIDWELL LP 1.50% of their portfolio STAMFORD, CT 3,592,9993.6m $44.9m $44.9m 1.50% New
5 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 2,947,2592.9m $33.9m $33.9m 0.00% New
6 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 2,109,6332.1m $26.4m $26.4m 0.00% New
7 ARCH Venture Management, LLC 3.59% of their portfolio CHICAGO, IL 1,944,4261.9m $24.3m $24.3m 3.59% New
8 HarbourVest Partners LLC 21.33% of their portfolio Boston, MA 1,722,2101.7m $21.5m $21.5m 21.33% New
9 BAKER BROS. ADVISORS LP 0.10% of their portfolio NEW YORK, NY 1,423,6021.4m $17.8m $17.8m 0.10% New
10 HARVARD MANAGEMENT CO INC 0.76% of their portfolio BOSTON, MA 1,111,1001.1m $13.9m $13.9m 0.76% New
11 NVIDIA CORP 0.06% of their portfolio SANTA CLARA, CA 833,325833.3k $10.4m $10.4m 0.06% New
12 Siren, L.L.C. 0.26% of their portfolio New York, NY 736,104736.1k $9.2m $9.2m 0.26% New
13 Davern Capital Partners, LP 2.03% of their portfolio NY, NY 591,800591.8k $7.4m $7.4m 2.03% New
14 Alyeska Investment Group, L.P. 0.02% of their portfolio CHICAGO, IL 500,000500.0k $6.2m $6.2m 0.02% New
15 ARK Investment Management LLC 0.05% of their portfolio ST. PETERSBURG, FL 498,408498.4k $6.2m $6.2m 0.05% New
16 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 376,893376.9k $4.7m $4.7m 0.00% New
17 UBS Group AG 0.00% of their portfolio ZURICH, V8 356,704356.7k $4.5m $4.5m 0.00% New
18 Affinity Asset Advisors, LLC 0.26% of their portfolio NEW YORK, NY 350,000350.0k $4.4m $4.4m 0.26% New
19 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 337,302337.3k $4.2m $4.2m 0.00% New
20 ExodusPoint Capital Management, LP 0.04% of their portfolio NEW YORK, NY 311,986312.0k $3.9m $3.9m 0.04% New
21 CenterBook Partners LP 0.18% of their portfolio GREENWICH, CT 266,813266.8k $3.3m $3.3m 0.18% New
22 SPHERA FUNDS MANAGEMENT LTD. 0.40% of their portfolio TEL AVIV, L3 185,000185.0k $2.3m $2.3m 0.40% New
23 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 170,695170.7k $2.1m $2.1m 0.00% New
24 VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio MALVERN, PA 131,319131.3k $1.6m $1.6m 0.00% First filing
25 SEVEN GRAND MANAGERS, LLC 0.10% of their portfolio BRONXVILLE, NY 125,000125.0k $1.6m $1.6m 0.10% New
26 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 123,371123.4k $1.5m $1.5m 0.00% New
27 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 118,243118.2k $1.5m $1.5m 0.00% New
28 LMR Partners LLP 0.01% of their portfolio LONDON, X0 100,000100.0k $1.2m $1.2m 0.01% New
29 SILVERARC CAPITAL MANAGEMENT, LLC 0.15% of their portfolio BOSTON, MA 100,000100.0k $1.2m $1.2m 0.15% New
30 D. E. Shaw & Co., Inc. 0.00% of their portfolio New York, NY 95,00095.0k $1.2m $1.2m 0.00% New
31 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 87,33587.3k $1.1m $1.1m 0.00% New
32 Balyasny Asset Management L.P. 0.00% of their portfolio Chicago, IL 79,48979.5k $993.6k $993.6k 0.00% New
33 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 74,31274.3k $928.9k $928.9k 0.00% New
34 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 70,89470.9k $886.2k $886.2k 0.00% New
35 HRT FINANCIAL LP 0.00% of their portfolio NEW YORK, NY 58,76258.8k $734.0k $734.0k 0.00% New
36 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 50,22150.2k $627.8k $627.8k 0.00% New
37 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 42,86642.9k $535.8k $535.8k 0.00% New
38 Sumitomo Mitsui Trust Group, Inc. 0.00% of their portfolio CHIYODA-KU, TOKYO, M0 40,34440.3k $504.3k $504.3k 0.00% New
39 Amova Asset Management Americas, Inc. 0.01% of their portfolio New York, NY 40,34440.3k $499.5k $499.5k 0.01% New
40 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 37,20337.2k $465.0k $465.0k 0.00% New
41 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 34,19634.2k $427.4k $427.4k 0.00% New
42 FEDERATED HERMES, INC. 0.00% of their portfolio PITTSBURGH, PA 30,00030.0k $375.0k $375.0k 0.00% New
43 TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio STAMFORD, CT 23,83323.8k $297.9k $297.9k 0.00% New
44 IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.02% of their portfolio DUBLIN 2, L2 19,20319.2k $240.0k $240.0k 0.02% New
45 Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio HONG KONG, K3 18,36218.4k $229.5k $229.5k 0.00% New
46 VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio MALVERN, PA 17,45617.5k $218.2k $218.2k 0.00% First filing
47 Hudson Bay Capital Management LP 0.00% of their portfolio STAMFORD, CT 16,67816.7k $208.5k $208.5k 0.00% New
48 Diametric Capital, LP 0.03% of their portfolio BOSTON, MA 10,49710.5k $131.2k $131.2k 0.03% New
49 Parallel Advisors, LLC 0.00% of their portfolio SAN FRANCISCO, CA 5,5505.5k $69.4k $69.4k 0.00% New
50 ALBION FINANCIAL GROUP /UT 0.00% of their portfolio SALT LAKE CITY, UT 4,8544.9k $60.7k $60.7k 0.00% New
51 FNY Investment Advisers, LLC 0.02% of their portfolio NEW YORK, NY 3,0003.0k $37.0k $37.0k 0.02% New
52 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 2,2442.2k $28.1k $28.1k 0.00% New
53 Vanguard Global Advisers, LLC 0.00% of their portfolio MALVERN, PA 1,2251.2k $15.3k $15.3k 0.00% First filing
54 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 1,2001.2k $15.0k $15.0k 0.00% New
55 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 231231 $3.0k $3.0k 0.00% New
56 Avion Wealth 0.00% of their portfolio THE WOODLANDS, TX 100100 $1.0k $1.0k 0.00% New
57 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 11 $12 $12 0.00% New