Vault-13

FULCRUM THERAPEUTICS INC FULC

COM · Common Stock · CUSIP 359616109

Company in Cambridge, United States

89 institutional holders -28 vs Q1 2023
55,466,58955.5m shares reported held*
89.7% of all shares outstanding*
$183.0mreported value*
15 new 26 added 31 reduced 41 sold out net sold ≈ $35.0m (-10.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($172.1k this quarter). Holder counts are more reliable. Shares outstanding: 61.8m as of 2023-07-27, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $3.30. Options: 6 managers hold calls ($2.2m notional), 5 hold puts ($261.8k).

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 106Q4 22: 111Q1 23: 117Q2 23: 8989Q3 22Q4 22Q1 23Q2 23
Numbers
QuarterHolders
Q3 2022106
Q4 2022111
Q1 2023117
Q2 202389

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 65 bought or addedQ4 22: 43 cut or sold outQ4 22Q1 23: 79 bought or addedQ1 23: 43 cut or sold outQ1 23Q2 23: 41 bought or addedQ2 23: 72 cut or sold outQ2 23
Numbers
QuarterBought or addedCut or sold out
Q4 20226543
Q1 20237943
Q2 20234172

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$2m$4m$6mQ3 22 calls: $5.2mQ3 22 puts: $312.0kQ3 22P/C 0.06Q4 22 calls: $4.2mQ4 22 puts: $379.7kQ4 22P/C 0.09Q1 23 calls: $2.0mQ1 23 puts: $137.5kQ1 23P/C 0.07Q2 23 calls: $2.2mQ2 23 puts: $261.8kQ2 23P/C 0.12
Numbers
QuarterCallsPutsP/C
Q3 2022$5.2m$312.0k0.06
Q4 2022$4.2m$379.7k0.09
Q1 2023$2.0m$137.5k0.07
Q2 2023$2.2m$261.8k0.12

Biggest buyers

CITADEL ADVISORS LLC Added +1,295,180+1.3m
COWEN AND COMPANY, LLC Added +940,951+941.0k
Woodline Partners LP New +596,695+596.7k
RTW INVESTMENTS, LP Added +552,284+552.3k
MONTANOVA CAPITAL, LLC Added +541,171+541.2k
ADAGE CAPITAL PARTNERS GP, L.L.C. Added +500,000+500.0k
TWO SIGMA ADVISERS, LP Added +332,700+332.7k
Tekla Capital Management LLC Added +198,351+198.4k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added +188,161+188.2k
RBF Capital, LLC New +154,100+154.1k

Biggest sellers

FMR LLC Reduced -6,758,916-6.8m
BlackRock Inc. Reduced -2,669,313-2.7m
Venrock Adviser, LLC Sold out -1,307,094-1.3m
Cormorant Asset Management, LP Sold out -1,081,490-1.1m
STATE STREET CORP Reduced -759,641-759.6k
Point72 Asset Management, L.P. Reduced -743,704-743.7k
GEODE CAPITAL MANAGEMENT, LLC Reduced -496,825-496.8k
NORTHERN TRUST CORP Reduced -308,525-308.5k
Nuveen Asset Management, LLC Sold out -288,737-288.7k
DIMENSIONAL FUND ADVISORS LP Reduced -279,551-279.6k

Biggest calls

CITADEL ADVISORS LLC Reduced $1.1m340.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $943.8k286.0k shares
WOLVERINE TRADING, LLC Reduced $47.7k14.9k shares
SIMPLEX TRADING, LLC Reduced $37.0k11.5k shares
GROUP ONE TRADING LLC Reduced $6.9k2.1k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $168.0k50.9k shares
CITADEL ADVISORS LLC Reduced $47.2k14.3k shares
SIMPLEX TRADING, LLC Added $43.0k13.2k shares
GROUP ONE TRADING LLC New $3.6k1.1k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
TANG CAPITAL MANAGEMENT LLC 13G · passive investor +2.2 pts · filed 2026-07-15 10.4% +2.2 pts 6.9m≈ $25.3m 2026-07-15
EcoR1 Capital, LLC 13G · institution no change · filed 2026-06-25 9.0% no change 6.0m≈ $22.0m 2026-06-25
Nantahala Capital Management, LLC 13G · institution +3.6 pts · filed 2026-08-14 8.2% +3.6 pts 5.5m≈ $20.0m 2026-08-14
BlackRock Portfolio Management LLC 13G · institution +2.1 pts · filed 2026-10-27 8.1% +2.1 pts 6.2m≈ $22.5m 2026-10-27
BlackRock, Inc. 13G · institution +1.2 pts · filed 2026-07-28 7.2% +1.2 pts 4.8m≈ $17.6m 2026-07-28
MONTANOVA CAPITAL, LLC 13G · institution -3.9 pts · filed 2026-08-14 5.5% -3.9 pts 3.7m≈ $13.5m 2026-08-14

Fell to 5% or below in the last year: BANK OF AMERICA CORP /DE/ (1.5%, 2026-10-28), RA CAPITAL MANAGEMENT, L.P. (0.0%, 2026-08-14), TCG Crossover GP II, LLC (0.0%, 2026-08-14), VANGUARD GROUP INC (0.0%, 2026-03-26)

Insider purchases and sales in Q2 2023

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
101Q3 21: 0 buyingQ3 21: 0 sellingQ4 21: 0 buyingQ4 21: 0 sellingQ4 21Q1 22: 0 buyingQ1 22: 0 sellingQ2 22: 0 buyingQ2 22: 1 sellingQ2 22Q3 22: 0 buyingQ3 22: 0 sellingQ4 22: 0 buyingQ4 22: 0 sellingQ4 22Q1 23: 0 buyingQ1 23: 1 sellingQ2 23: 0 buyingQ2 23: 1 sellingQ2 23
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20210—0——
Q4 20210—0——
Q1 20220—0——
Q2 20220—1$3.5m—
Q3 20220—0——
Q4 20220—0——
Q1 20230—1$101.5k—
Q2 20230—1$695—
DateInsiderTradeSharesPrice ValueTheir holding
2023-05-10 Tourangeau Greg Principal Accounting Officer Sold 210 $3.31 $695210 shares -1%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 RA CAPITAL MANAGEMENT, L.P. 0.72% of their portfolio BOSTON, MA 11,609,70411.6m $38.3m $38.3m 0.72% Unchanged
2 RTW INVESTMENTS, LP 0.38% of their portfolio NEW YORK, NY 6,064,1236.1m $20.0m $20.0m 0.38% Added +552.3k +552,284
3 MONTANOVA CAPITAL, LLC 1.01% of their portfolio New York, NY 5,718,8815.7m $18.9m $18.9m 1.01% Added +541.2k +541,171
4 FMR LLC 0.00% of their portfolio BOSTON, MA 5,553,7405.6m $18.3m $18.3m 0.00% Reduced -6.8m -6,758,916
5 COWEN AND COMPANY, LLC 0.85% of their portfolio NEW YORK, NY 3,116,9963.1m $10.3m $10.3m 0.85% Added +941.0k +940,951
6 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 2,626,0292.6m $8.7m $8.7m 0.00% Reduced -252.5k -252,462
7 TRV GP IV, LLC 6.99% of their portfolio Boston, MA 2,343,1542.3m $7.7m $7.7m 6.99% Unchanged
8 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.02% of their portfolio Boston, MA 2,306,4222.3m $7.6m $7.6m 0.02% Added +500.0k +500,000
9 Point72 Asset Management, L.P. 0.02% of their portfolio STAMFORD, CT 1,899,9681.9m $6.3m $6.3m 0.02% Reduced -743.7k -743,704
10 BlackRock Inc. 0.00% of their portfolio New York, NY 1,514,4251.5m $5.0m $5.0m 0.00% Reduced -2.7m -2,669,313
11 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 1,504,6391.5m $5.0m $5.0m 0.01% Added +1.3m +1,295,180
12 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 1,103,8741.1m $3.6m $3.6m 0.00% Reduced -58.5k -58,494
13 Rock Springs Capital Management LP 0.06% of their portfolio Baltimore, MD 727,673727.7k $2.4m $2.4m 0.06% Unchanged
14 Simplify Asset Management Inc. 0.42% of their portfolio Las Vegas, NV 696,296696.3k $2.3m $2.3m 0.42% Added +57.2k +57,178
15 Woodline Partners LP 0.02% of their portfolio San Francisco, CA 596,695596.7k $2.0m $2.0m 0.02% New
16 TWO SIGMA ADVISERS, LP 0.01% of their portfolio NEW YORK, NY 595,300595.3k $2.0m $2.0m 0.01% Added +332.7k +332,700
17 TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio NEW YORK, NY 577,866577.9k $1.9m $1.9m 0.01% Reduced -71.9k -71,944
18 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 574,857574.9k $1.9m $1.9m 0.00% Reduced -45.7k -45,702
19 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 565,809565.8k $1.9m $1.9m 0.00% Reduced -496.8k -496,825
20 Vivo Capital, LLC 0.13% of their portfolio Palo Alto, CA 550,000550.0k $1.8m $1.8m 0.13% Unchanged
21 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 475,335475.3k $1.6m $1.6m 0.00% Reduced -279.6k -279,551
22 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 387,732387.7k $1.3m $1.3m 0.00% Added +89.9k +89,921
23 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 344,810344.8k $1.1m $1.1m 0.00% Reduced -45.3k -45,290
24 HARVARD MANAGEMENT CO INC 0.11% of their portfolio BOSTON, MA 341,972342.0k $1.1m $1.1m 0.11% Reduced -68.7k -68,742
25 BESSEMER GROUP INC 0.00% of their portfolio WOODBRIDGE, NJ 286,988287.0k $947.0k $947.0k 0.00% Unchanged
26 Tekla Capital Management LLC 0.03% of their portfolio Boston, MA 256,888256.9k $847.7k $847.7k 0.03% Added +198.4k +198,351
27 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 247,228247.2k $815.9k $815.9k 0.00% Added +188.2k +188,161
28 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 205,947205.9k $679.6k $679.6k 0.00% Reduced -759.6k -759,641
29 Alyeska Investment Group, L.P. 0.01% of their portfolio CHICAGO, IL 202,148202.1k $667.1k $667.1k 0.01% Added +50.0k +50,000
30 RBF Capital, LLC 0.03% of their portfolio RENO, NV 154,100154.1k $508.5k $508.5k 0.03% New
31 D. E. Shaw & Co., Inc. 0.00% of their portfolio New York, NY 146,222146.2k $482.5k $482.5k 0.00% Added +130.9k +130,899
32 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 144,983145.0k $478.4k $478.4k 0.00% Added +117.7k +117,730
33 Opaleye Management Inc. 0.11% of their portfolio BOSTON, MA 143,600143.6k $473.9k $473.9k 0.11% New
34 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 143,427143.4k $473.3k $473.3k 0.00% Reduced -308.5k -308,525
35 Fiduciary Trust Co 0.01% of their portfolio Boston, MA 136,555136.6k $450.6k $450.6k 0.01% Unchanged
36 Acuitas Investments, LLC 0.26% of their portfolio Seattle, WA 134,815134.8k $444.9k $444.9k 0.26% New
37 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 132,238132.2k $436.4k $436.4k 0.00% Added +89.9k +89,868
38 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio HOUSTON, TX 126,500126.5k $417.4k $417.4k 0.01% New
39 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 117,000117.0k $386.1k $386.1k 0.00% Added +22.2k +22,230
40 Squarepoint Ops LLC 0.00% of their portfolio NEW YORK, NY 100,791100.8k $332.6k $332.6k 0.00% Reduced -218.9k -218,920
41 XTX Topco Ltd 0.05% of their portfolio LONDON, X0 83,16683.2k $274.4k $274.4k 0.05% Reduced -40.6k -40,602
42 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 66,29366.3k $218.8k $218.8k 0.00% Added +52.0k +52,039
43 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 62,32262.3k $205.7k $205.7k 0.00% Reduced -149.9k -149,879
44 Y-Intercept (Hong Kong) Ltd 0.02% of their portfolio HONG KONG, K3 61,58761.6k $203.2k $203.2k 0.02% Added +31.9k +31,924
45 Verition Fund Management LLC 0.00% of their portfolio GREENWICH, CT 59,54959.5k $196.5k $196.5k 0.00% Added +47.8k +47,777
46 MYDA Advisors LLC 0.06% of their portfolio WOODMERE, NY 50,00050.0k $165.0k $165.0k 0.06% New
47 Ergoteles LLC 0.01% of their portfolio NEW YORK, NY 40,80040.8k $134.6k $134.6k 0.01% New
48 Laurion Capital Management LP 0.00% of their portfolio NEW YORK, NY 33,64533.6k $111.0k $111.0k 0.00% New
49 MIRABELLA FINANCIAL SERVICES LLP 0.01% of their portfolio London, X0 32,76032.8k $108.1k $108.1k 0.01% New
50 Point72 Middle East FZE 0.01% of their portfolio DUBAI, C0 32,14532.1k $106.1k $106.1k 0.01% Added +27.8k +27,834
51 Graham Capital Management, L.P. 0.00% of their portfolio ROWAYTON, CT 31,94831.9k $105.4k $105.4k 0.00% Reduced -115.0k -115,031
52 UBS Group AG 0.00% of their portfolio ZURICH, V8 31,75931.8k $104.8k $104.8k 0.00% Added +31.3k +31,335
53 COUNTRY TRUST BANK 0.00% of their portfolio Bloomington, IL 30,18630.2k $99.6k $99.6k 0.00% Unchanged
54 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 28,41728.4k $93.8k $93.8k 0.00% Added +8.2k +8,214
55 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 28,35628.4k $93.6k $93.6k 0.00% New
56 Marquette Asset Management, LLC 0.02% of their portfolio MINNEAPOLIS, MN 27,86727.9k $92.0k $92.0k 0.02% New
57 BRANDYWINE MANAGERS, LLC 0.06% of their portfolio HOCKESSIN, DE 26,12726.1k $86.2k $86.2k 0.06% Unchanged
58 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 25,69925.7k $73.2k $73.2k 0.00% Unchanged
59 STIFEL FINANCIAL CORP 0.00% of their portfolio ST. LOUIS, MO 25,48825.5k $84.1k $84.1k 0.00% Reduced -8.6k -8,612
60 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 24,48524.5k $80.8k $80.8k 0.00% Reduced -116.8k -116,826
61 OLD MISSION CAPITAL LLC 0.00% of their portfolio CHICAGO, IL 23,90023.9k $78.9k $78.9k 0.00% New
62 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.00% of their portfolio BALA CYNWYD, PA 22,59422.6k $74.6k $74.6k 0.00% Reduced -18.9k -18,940
63 Nantahala Capital Management, LLC 0.01% of their portfolio NEW CANAAN, CT 21,37021.4k $70.5k $70.5k 0.01% Unchanged
64 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 21,20021.2k $70.0k $70.0k 0.00% Reduced -15.3k -15,261
65 Blackstone Inc. 0.00% of their portfolio NEW YORK, NY 19,21619.2k $63.4k $63.4k 0.00% Unchanged
66 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 17,40017.4k $57.4k $57.4k 0.00% Reduced -103.6k -103,600
67 PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio DES MOINES, IA 17,06217.1k $56.3k $56.3k 0.00% Added +1.8k +1,770
68 Alphabet Inc. 0.00% of their portfolio Mountain View, CA 14,26214.3k $47.1k $47.1k 0.00% Unchanged
69 Quantamental Technologies LLC 0.02% of their portfolio WHITE PLAINS, NY 11,85511.9k $39.1k $39.1k 0.02% Reduced -300 -300
70 PRELUDE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio NEW YORK, NY 11,17111.2k $36.9k $36.9k 0.00% New
71 Balyasny Asset Management L.P. 0.00% of their portfolio Chicago, IL 11,08711.1k $36.6k $36.6k 0.00% New
72 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 11,02011.0k $36.4k $36.4k 0.00% Added +5.1k +5,100
73 DRW Securities, LLC 0.00% of their portfolio CHICAGO, IL 11,00011.0k $36.0k $36.0k 0.00% New
74 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 7,9037.9k $26.1k $26.1k 0.00% Added +6.2k +6,193
75 PrairieView Partners, LLC 0.00% of their portfolio ST. PAUL, MN 5,0005.0k $16.0k $16.0k 0.00% Added +1.4k +1,400
76 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 4,7914.8k $15.8k $15.8k 0.00% Reduced -70.7k -70,716
77 Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio ZURICH, V8 2,6912.7k $8.9k $8.9k 0.00% Reduced -7.8k -7,758
78 NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio ST. LOUIS, MO 1,5421.5k $5.1k $5.1k 0.00% Added +42 +42
79 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 1,3141.3k $4.3k $4.3k 0.00% Reduced -189.0k -188,955
80 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 965965 $3.2k $3.2k 0.00% Reduced -8.8k -8,801
81 China Universal Asset Management Co., Ltd. 0.00% of their portfolio SHANGHAI, F4 810810 $2.7k $2.7k 0.00% Reduced -26 -26
82 Steward Partners Investment Advisory, LLC 0.00% of their portfolio STAMFORD, CT 790790 $2.6k $2.6k 0.00% Unchanged
83 NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio MONTREAL, A8 460460 $1.5k $1.5k 0.00% Unchanged
84 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 448448 $1.0k $1.0k 0.00% Reduced -792 -792
85 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 376376 $1.2k $1.2k 0.00% Reduced -15.5k -15,467
86 Daiwa Securities Group Inc. 0.00% of their portfolio CHIYODA-KU,TOKYO, M0 138138 $0 $0 0.00% Unchanged
87 NewSquare Capital LLC 0.00% of their portfolio NEWTOWN SQUARE, PA 3030 $99 $99 0.00% Unchanged
88 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 1010 $0 $0 0.00% Reduced -2.9k -2,884
89 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged