4D MOLECULAR THERAPEUTICS IN FDMT
COM · Common Stock · CUSIP 35104E100
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersEmeryville, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($18 this quarter). Holder counts are more reliable. Shares outstanding: 42.1m as of 2023-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $18.07. Options: 5 managers hold calls ($1.3m notional), 6 hold puts ($1.9m).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 88 |
| Q4 2022 | 97 |
| Q1 2023 | 95 |
| Q2 2023 | 101 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 52 | 52 |
| Q1 2023 | 53 | 40 |
| Q2 2023 | 68 | 35 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $760.0k | $0 | 0.00 |
| Q4 2022 | $2.7m | $980.8k | 0.36 |
| Q1 2023 | $1.9m | $2.6m | 1.40 |
| Q2 2023 | $1.3m | $1.9m | 1.46 |
Biggest buyers
| RA CAPITAL MANAGEMENT, L.P. | New | +3.1m |
| Venrock Adviser, LLC | New | +3.0m |
| JANUS HENDERSON GROUP PLC | Added | +961.5k |
| VIKING GLOBAL INVESTORS LP | Added | +850.0k |
| DEERFIELD MANAGEMENT COMPANY, L.P. | New | +650.0k |
| DEUTSCHE BANK AG\ | Added | +595.9k |
| Deep Track Capital, LP | Added | +500.0k |
| VANGUARD GROUP INC | Added | +427.2k |
| BlackRock Inc. | Added | +363.7k |
| GREAT POINT PARTNERS LLC | New | +350.0k |
Biggest sellers
| Octagon Capital Advisors LP | Sold out | -500.0k |
| Soleus Capital Management, L.P. | Reduced | -250.3k |
| MORGAN STANLEY | Reduced | -174.1k |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | Reduced | -138.2k |
| ACUTA CAPITAL PARTNERS, LLC | Sold out | -104.8k |
| Opaleye Management Inc. | Reduced | -92.3k |
| BANK OF AMERICA CORP /DE/ | Reduced | -90.4k |
| D. E. Shaw & Co., Inc. | Sold out | -81.5k |
| Vontobel Holding Ltd. | Sold out | -80.5k |
| SECTORAL ASSET MANAGEMENT INC | Sold out | -80.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $910.7k50.4k shares |
| CITADEL ADVISORS LLC | Added | $182.5k10.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $130.0k7.2k shares |
| GROUP ONE TRADING LLC | Added | $72.3k4.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| Caption Management, LLC | New | $1.3m71.9k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $309.0k17.1k shares |
| CITADEL ADVISORS LLC | Added | $216.8k12.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $48.0k2.7k shares |
| GROUP ONE TRADING LLC | New | $18.1k1.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| JANUS HENDERSON GROUP PLC 13G · institution +2.2 pts · filed 2026-04-07 | 10.3% |
| BIOTECHNOLOGY VALUE FUND L P 13G · passive investor no change · filed 2026-05-15 | 10.0% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor no change · filed 2026-05-15 | 9.9% |
| GOLDMAN SACHS GROUP INC 13G · institution -2.1 pts · filed 2026-02-09 | 7.5% |
| BlackRock, Inc. 13G · institution -1.2 pts · filed 2025-10-17 | 6.6% |
| Novo Holdings A/S 13G · passive investor -0.4 pts · filed 2026-02-17 | 6.4% |
| STATE STREET CORP 13G · institution new · filed 2026-05-12 | 5.3% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 1 | $1.1m | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 2 | $2.2m | — |
| Q1 2023 | 0 | — | 2 | $1.1m | — |
| Q2 2023 | 0 | — | 2 | $294.6k | $175.2k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-06-08 | Bizily Scott Chief Legal and HR Officer | Sold | $78.2k3.8k shares |
| 2023-06-01 | Bizily Scott Chief Legal and HR Officer | Sold | $41.1k2.2k shares |
| 2023-05-09 | VIKING GLOBAL INVESTORS LP +7 10% owner · See Explanation Responses | Bought | $13.6m850.0k shares |
| 2023-04-21 | Chacko Jacob Director | Sold plan | $100.2k5.0k shares |
| 2023-04-21 | Bizily Scott Chief Legal and HR Officer | Sold plan | $75.0k3.8k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| VIKING GLOBAL INVESTORS LP 0.35% of their portfolio | 4.8m $86.5m | Added +850.0k |
| BVF INC/IL 2.02% of their portfolio | 4.0m $72.4m | Unchanged |
| RA CAPITAL MANAGEMENT, L.P. 1.05% of their portfolio | 3.1m $55.5m | New |
| Venrock Adviser, LLC 8.67% of their portfolio | 3.0m $54.2m | New |
| BlackRock Inc. 0.00% of their portfolio | 2.9m $52.7m | Added +363.7k |
| JANUS HENDERSON GROUP PLC 0.03% of their portfolio | 2.8m $51.3m | Added +961.5k |
| Deep Track Capital, LP 2.34% of their portfolio | 2.8m $50.2m | Added +500.0k |
| STATE STREET CORP 0.00% of their portfolio | 2.1m $37.1m | Added +8.2k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.0m $35.7m | Added +427.2k |
| MORGAN STANLEY 0.00% of their portfolio | 1.6m $28.3m | Reduced -174.1k |
| Casdin Capital, LLC 1.69% of their portfolio | 1.1m $19.3m | Unchanged |
| ArrowMark Colorado Holdings LLC 0.20% of their portfolio | 1.0m $18.6m | Reduced -1.3k |
| NOVO HOLDINGS A/S 1.40% of their portfolio | 1.0m $18.1m | Added +300.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 689.8k $12.5m | Added +111.9k |
| DEUTSCHE BANK AG\ 0.01% of their portfolio | 676.2k $12.2m | Added +595.9k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.25% of their portfolio | 650.0k $11.7m | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 457.2k $8.3m | Added +16.9k |
| Eagle Health Investments LP 1.48% of their portfolio | 437.9k $7.9m | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 431.1k $7.8m | Added +284.2k |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 370.9k $6.7m | Added +162.0k |
| GREAT POINT PARTNERS LLC 1.27% of their portfolio | 350.0k $6.3m | New |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.03% of their portfolio | 334.3k $6.0m | Reduced -138.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 332.4k $6.0m | Added +57.9k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 278.7k $5.0m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 266.1k $4.8m | Added +48.0k |
| Perigon Wealth Management, LLC 0.17% of their portfolio | 246.1k $4.4m | Unchanged |
| Opaleye Management Inc. 0.96% of their portfolio | 221.7k $4.0m | Reduced -92.3k |
| Soleus Capital Management, L.P. 0.44% of their portfolio | 219.1k $4.0m | Reduced -250.3k |
| Invesco Ltd. 0.00% of their portfolio | 215.6k $3.9m | New |
| Rafferty Asset Management, LLC 0.02% of their portfolio | 197.2k $3.6m | Added +62.4k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 194.3k $3.5m | Reduced -3.5k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 185.1k $3.3m | Reduced -15.7k |
| Candriam S.C.A. 0.02% of their portfolio | 173.0k $3.1m | Reduced -62.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 169.1k $3.1m | Reduced -6.4k |
| FIRST MANHATTAN CO. LLC. 0.01% of their portfolio | 144.5k $2.6m | New |
| BARCLAYS PLC 0.00% of their portfolio | 142.5k $2.6m | Added +85.2k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.01% of their portfolio | 135.7k $2.5m | Added +23.6k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 116.3k $2.1m | Added +7.8k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 112.3k $2.0m | Added +12.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 102.5k $1.9m | Reduced -90.4k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 97.3k $1.8m | Reduced -59.3k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 88.6k $1.6m | Added +71.5k |
| Verition Fund Management LLC 0.02% of their portfolio | 72.7k $1.3m | New |
| EcoR1 Capital, LLC 0.03% of their portfolio | 67.0k $1.2m | New |
| Swiss National Bank 0.00% of their portfolio | 61.6k $1.1m | Added +23.1k |
| CITIGROUP INC 0.00% of their portfolio | 58.2k $1.1m | Reduced -53.5k |
| UBS Group AG 0.00% of their portfolio | 53.9k $973.1k | Added +1.5k |
| Blackstone Inc. 0.00% of their portfolio | 50.0k $903.5k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 49.0k $885.2k | Added +1.5k |
| Bellevue Group AG 0.01% of their portfolio | 45.0k $813.1k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 41.8k $755.0k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 39.1k $706.2k | Added +11.1k |
| Ergoteles LLC 0.03% of their portfolio | 35.9k $649.1k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 35.6k $643.2k | Added +8.8k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 35.1k $633.6k | Added +18.6k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 34.6k $625.5k | Added +21.2k |
| M&T Bank Corp 0.00% of their portfolio | 28.8k $520.3k | Unchanged |
| PROFUND ADVISORS LLC 0.03% of their portfolio | 28.8k $520.0k | Added +3.7k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 27.4k $495.1k | Unchanged |
| Ghisallo Capital Management LLC 0.05% of their portfolio | 25.0k $451.8k | New |
| Legal & General Group Plc 0.00% of their portfolio | 24.2k $436.9k | Added +17.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 22.5k $407.4k | Reduced -56.0k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 21.8k $394.4k | Reduced -27.0k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 20.3k $364.8k | Added +466 |
| Elmwood Wealth Management, Inc. 0.17% of their portfolio | 19.8k $357.8k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 18.9k $342.0k | Added +539 |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 18.9k $341.3k | Added +14.0k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 17.4k $314.0k | Unchanged |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 15.2k $274.7k | Added +718 |
| Squarepoint Ops LLC 0.00% of their portfolio | 14.7k $265.5k | Reduced -46.7k |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.00% of their portfolio | 14.5k $261.3k | Added +2.4k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 14.4k $260.5k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 13.6k $246.0k | Reduced -2.5k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 12.7k $229.7k | Added +689 |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 12.6k $227.4k | Added +876 |
| Caption Management, LLC 0.04% of their portfolio | 11.9k $215.8k | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 10.1k $174.5k | Unchanged |
| Sandia Investment Management LP 0.04% of their portfolio | 7.5k $135.5k | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 7.0k $126.3k | Added +5.9k |
| VIRTUS ADVISERS, LLC 0.05% of their portfolio | 4.9k $89.0k | Added +783 |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 4.8k $86.0k | Added +4.6k |
| AMALGAMATED BANK 0.00% of their portfolio | 3.3k $59.0k | Added +80 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 3.2k $59.0k | Added +1.5k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 3.0k $54.8k | Reduced -5.3k |
| FMR LLC 0.00% of their portfolio | 2.8k $51.2k | Reduced -2.6k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 2.6k $47.1k | Added +449 |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 2.2k $38.0k | Added +671 |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 1.9k $34.0k | Added +682 |
| Metropolitan Life Insurance Co/NY 0.00% of their portfolio | 1.8k $31.8k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 1.6k $28.5k | Reduced -211 |
| Itau Unibanco Holding S.A. 0.00% of their portfolio | 1.1k $20.5k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 1.1k $20.3k | Unchanged |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 1.0k $18.8k | Added +250 |
| Cutler Group LLC / CA 0.00% of their portfolio | 1.0k $18.0k | Added +900 |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 549 $9.9k | Added +110 |
| US BANCORP \DE\ 0.00% of their portfolio | 264 $4.8k | New |
| Impact Partnership Wealth, LLC 0.00% of their portfolio | 57 $1.0k | First filing |
| NFSG Corp 0.00% of their portfolio | 30 $542 | Unchanged |
| SIGNATUREFD, LLC 0.00% of their portfolio | 22 $398 | New |
| Cubist Systematic Strategies, LLC 0.00% of their portfolio | 1 $18 | Reduced -1.8k |