STANDARD BIOTOOLS INC LAB
COM · Common Stock · CUSIP 34385P108
Company in South San Francisco, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBoston, MA
- Founded1999
- Websitestandardbio.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($7.0m this quarter). Holder counts are more reliable. Shares outstanding: 384.6m as of 2025-11-02, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.30. Options: 4 managers hold calls ($108.6k notional), 3 hold puts ($69.0k).
Trends to Q3 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 66 |
| Q4 2022 | 68 |
| Q1 2023 | 69 |
| Q2 2023 | 67 |
| Q3 2023 | 73 |
| Q4 2023 | 87 |
| Q1 2024 | 146 |
| Q2 2024 | 146 |
| Q3 2024 | 142 |
| Q4 2024 | 143 |
| Q1 2025 | 146 |
| Q2 2025 | 161 |
| Q3 2025 | 155 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2023 | 48 | 26 |
| Q1 2024 | 120 | 24 |
| Q2 2024 | 73 | 70 |
| Q3 2024 | 57 | 67 |
| Q4 2024 | 62 | 62 |
| Q1 2025 | 61 | 57 |
| Q2 2025 | 73 | 58 |
| Q3 2025 | 63 | 60 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2024 | $11.7k | $177.9k | 15.17 |
| Q1 2025 | $6.5k | $62.4k | 9.63 |
| Q2 2025 | $68.1k | $49.1k | 0.72 |
| Q3 2025 | $108.6k | $69.0k | 0.64 |
Biggest buyers
| MAK CAPITAL ONE LLC | Added | +10.3m |
| Casdin Capital, LLC | Added | +1.5m |
| Long Focus Capital Management, LLC | Added | +1.3m |
| JBF Capital, Inc. | New | +770.7k |
| JANE STREET GROUP, LLC | Added | +357.4k |
| VANGUARD GROUP INC | Added | +263.8k |
| NEUBERGER BERMAN GROUP LLC | Added | +212.6k |
| ROYCE & ASSOCIATES LP | Added | +167.6k |
| Hollow Brook Wealth Management LLC | Added | +165.4k |
| CITADEL ADVISORS LLC | Added | +139.3k |
Biggest sellers
| MIRABELLA FINANCIAL SERVICES LLP | Sold out | -3.4m |
| Tikvah Management LLC | Reduced | -1.5m |
| Kent Lake PR LLC | Sold out | -1.0m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -907.2k |
| Sumitomo Mitsui Trust Group, Inc. | Reduced | -773.7k |
| Amova Asset Management Americas, Inc. | Reduced | -764.3k |
| Rockefeller Capital Management L.P. | Reduced | -351.2k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -340.7k |
| GSA CAPITAL PARTNERS LLP | Sold out | -306.5k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | Reduced | -231.0k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $59.1k45.5k shares |
| SIMPLEX TRADING, LLC | Added | $23.0k17.9k shares |
| WOLVERINE TRADING, LLC | New | $18.0k14.2k shares |
| GROUP ONE TRADING LLC | Added | $8.4k6.5k shares |
Biggest puts
| GROUP ONE TRADING LLC | Reduced | $44.7k34.4k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $24.3k18.7k shares |
| SIMPLEX TRADING, LLC | Unchanged | $0400 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Casdin Capital, LLC
13D · may seek influence
-0.3 pts · filed 2026-06-09
Stated purposeItem 4 of the Schedule 13D amendment filed on November 28, 2025 is hereby supplemented by the addition of the following: On June 6, 2026, the Issuer, Treeline Biosciences, Inc., a Delaware corporation (the "Company"), and Siri Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Issuer ("Merger Sub"), entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"), pursuant to which, among other matters, and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, Merger Sub will merge with and into the Company, with the Company continuing as a wholly owned subsidiary of the Issuer and the surviving corporation of the merger (the "Merger"). Upon the terms and subject to the conditions set forth in the Merg… Full filing |
23.9% |
VIKING GLOBAL INVESTORS LP
13D · may seek influence
no change · filed 2026-06-12
Stated purposeThe response to Item 3 of this Schedule 13D is incorporated by reference herein. On June 6, 2026, the Issuer, Treeline Biosciences, Inc., a Delaware corporation ("Treeline"), and Siri Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Issuer ("Merger Sub"), entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"), pursuant to which, among other matters, and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, Merger Sub will merge with and into Treeline, with Treeline continuing as a wholly owned subsidiary of the Issuer and the surviving corporation of the merger (the "Merger"). Upon the terms and subject to the conditions set forth in the Merger Agreement, at the effective time of the Merger… Full filing |
15.0% |
| MAK CAPITAL ONE LLC 13G · passive investor filed 2026-08-14 | 7.3% |
| MAK Capital Fund LP 13G · passive investor +1.5 pts · filed 2026-05-15 | 6.7% |
| Long Focus Capital Management, LLC 13G · institution new · filed 2026-08-14 | 6.0% |
Fell to 5% or below in the last year: BlackRock, Inc. (2.0%, 2026-07-30)
Insider purchases and sales in Q3 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 1 | $646.2k | 0 | — | — |
| Q2 2024 | 1 | $5.3m | 0 | — | — |
| Q3 2024 | 1 | $12.6m | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 1 | $5.2m | 0 | — | — |
| Q2 2025 | 0 | — | 3 | $57.5k | — |
| Q3 2025 | 1 | $1.9m | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-09-09 | Casdin Partners GP, LLC +7 Director · See footnote | Bought | $129.0k100.0k shares |
| 2025-09-04 | Casdin Partners GP, LLC +7 Director · See footnote | Bought | $320.0k250.0k shares |
| 2025-09-03 | Casdin Partners GP, LLC +7 Director · See footnote | Bought | $317.5k250.0k shares |
| 2025-08-26 | Casdin Partners GP, LLC +7 Director · See footnote | Bought | $157.5k125.0k shares |
| 2025-08-25 | Casdin Partners GP, LLC +7 Director · See footnote | Bought | $248.0k200.0k shares |
| 2025-08-22 | Casdin Partners GP, LLC +7 Director · See footnote | Bought | $252.0k200.0k shares |
| 2025-08-15 | Casdin Partners GP, LLC +7 Director · See footnote | Bought | $183.0k150.0k shares |
| 2025-08-14 | Casdin Partners GP, LLC +7 Director · See footnote | Bought | $161.2k133.2k shares |
| 2025-08-13 | Casdin Partners GP, LLC +7 Director · See footnote | Bought | $98.2k75.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2025
| Manager | Shares | Change |
|---|---|---|
| Casdin Capital, LLC 8.41% of their portfolio | 77.6m $100.8m | Added +1.5m |
| VIKING GLOBAL INVESTORS LP 0.20% of their portfolio | 58.7m $76.2m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 24.9m $32.4m | Added +96.2k |
| VANGUARD GROUP INC 0.00% of their portfolio | 17.2m $22.4m | Added +263.8k |
| MAK CAPITAL ONE LLC 4.13% of their portfolio | 15.9m $20.7m | Added +10.3m |
| Long Focus Capital Management, LLC 0.84% of their portfolio | 11.4m $14.8m | Added +1.3m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 7.5m $9.7m | Added +27.8k |
| STATE STREET CORP 0.00% of their portfolio | 6.4m $8.3m | Added +101.4k |
| MORGAN STANLEY 0.00% of their portfolio | 6.4m $8.3m | Added +129.1k |
| Hollow Brook Wealth Management LLC 1.78% of their portfolio | 5.8m $7.5m | Added +165.4k |
| Sumitomo Mitsui Trust Group, Inc. 0.00% of their portfolio | 5.4m $7.0m | Reduced -773.7k |
| Amova Asset Management Americas, Inc. 0.07% of their portfolio | 5.4m $7.0m | Reduced -764.3k |
| NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio | 4.7m $6.1m | Added +212.6k |
| Tikvah Management LLC 1.36% of their portfolio | 3.6m $4.6m | Reduced -1.5m |
| BARCLAYS PLC 0.00% of their portfolio | 3.2m $4.1m | Reduced -131.7k |
| ARK Investment Management LLC 0.02% of their portfolio | 3.0m $3.9m | Reduced -133.3k |
| ROYCE & ASSOCIATES LP 0.04% of their portfolio | 2.8m $3.6m | Added +167.6k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 2.6m $3.4m | Reduced -65.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 2.5m $3.3m | Reduced -37.7k |
| Nan Fung Group Holdings Ltd 4.11% of their portfolio | 1.9m $2.4m | Unchanged |
| Slate Path Capital LP 0.03% of their portfolio | 1.6m $2.1m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 1.5m $1.9m | Reduced -907.2k |
| Pacific Capital Partners Ltd 1.92% of their portfolio | 1.3m $1.7m | Reduced -50.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 1.3m $1.7m | Reduced -23.1k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 798.1k $1.0m | Added +20.4k |
| JBF Capital, Inc. 0.14% of their portfolio | 770.7k $1.0m | New |
| Nuveen, LLC 0.00% of their portfolio | 657.2k $854.4k | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 512.7k $666.5k | Reduced -231.0k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 488.4k $635.0k | Added +139.3k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 488.1k $634.5k | Reduced -124.0k |
| Swiss National Bank 0.00% of their portfolio | 470.7k $611.9k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 455.8k $592.6k | Added +77.9k |
| NEEDHAM INVESTMENT MANAGEMENT LLC 0.04% of their portfolio | 434.4k $564.8k | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 420.6k $546.8k | Reduced -52.4k |
| TANG CAPITAL MANAGEMENT LLC 0.02% of their portfolio | 407.8k $530.1k | Unchanged |
| Intellectus Partners, LLC 0.10% of their portfolio | 404.7k $526.1k | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 393.0k $510.9k | Added +357.4k |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 331.2k $430.6k | Reduced -351.2k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 315.7k $410.4k | Unchanged |
| JOHNSON & JOHNSON 0.08% of their portfolio | 312.0k $405.6k | Unchanged |
| GM Advisory Group, LLC 0.02% of their portfolio | 300.0k $390.0k | Added +100.0k |
| Legal & General Group Plc 0.00% of their portfolio | 291.9k $379.5k | Reduced -18.5k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 282.8k $367.7k | Reduced -158.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 250.7k $325.9k | Added +106.5k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 245.0k $318.5k | Added +27.8k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 243.0k $315.9k | Added +37.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 210.5k $273.7k | Added +18.6k |
| Invesco Ltd. 0.00% of their portfolio | 188.2k $244.6k | Added +8.3k |
| PRIMECAP MANAGEMENT CO/CA/ 0.00% of their portfolio | 176.2k $229.0k | Reduced -112.6k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 157.5k $205.0k | Reduced -52.1k |
| Front Street Capital Management, Inc. 0.03% of their portfolio | 153.2k $199.0k | Added +32.7k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 152.9k $198.8k | Reduced -28.3k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 140.6k $182.8k | Reduced -23.3k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 136.1k $177.0k | Reduced -12.9k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 131.6k $171.8k | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 131.2k $170.6k | Reduced -6.0k |
| Evercore Wealth Management, LLC 0.00% of their portfolio | 125.0k $162.5k | Unchanged |
| Impact Partnership Wealth, LLC 0.02% of their portfolio | 110.4k $143.5k | Added +55.7k |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 108.6k $137.0k | Added +87.1k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 106.1k $138.0k | Reduced -9.2k |
| Abich Financial Wealth Management LLC 0.04% of their portfolio | 91.4k $118.9k | First filing |
| OPPENHEIMER & CO INC 0.00% of their portfolio | 86.6k $112.6k | Unchanged |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 86.0k $111.8k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 86.0k $111.8k | Added +25.3k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 79.0k $102.7k | Unchanged |
| SEI INVESTMENTS CO 0.00% of their portfolio | 73.6k $95.7k | Added +8.0k |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.01% of their portfolio | 73.3k $95.4k | Added +28.1k |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 73.1k $95.0k | Added +1.8k |
| Creative Planning 0.00% of their portfolio | 63.0k $81.9k | Added +1.9k |
| Virtu Financial LLC 0.00% of their portfolio | 58.7k $76.0k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 58.4k $75.9k | Reduced -28.9k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 58.3k $75.8k | Added +28.5k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 58.1k $75.6k | Reduced -340.7k |
| HighTower Advisors, LLC 0.00% of their portfolio | 52.8k $68.6k | Reduced -171.4k |
| ProShare Advisors LLC 0.00% of their portfolio | 51.2k $66.5k | Reduced -10.2k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 50.3k $65.4k | Unchanged |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 46.5k $60.5k | Added +630 |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 45.7k $59.2k | Reduced -10.5k |
| Corvex Management LP 0.00% of their portfolio | 44.4k $57.7k | Unchanged |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 0.00% of their portfolio | 42.6k $55.0k | Unchanged |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 42.1k $54.7k | Reduced -1.5k |
| KLP KAPITALFORVALTNING AS 0.00% of their portfolio | 40.2k $52.2k | Unchanged |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 39.3k $51.1k | Unchanged |
| BOOTHBAY FUND MANAGEMENT, LLC 0.00% of their portfolio | 36.7k $47.7k | New |
| Cerity Partners LLC 0.00% of their portfolio | 36.6k $47.6k | Reduced -913 |
| SG Americas Securities, LLC 0.00% of their portfolio | 33.0k $43.0k | Added +20.7k |
| CIBC Bancorp USA Inc. 0.00% of their portfolio | 31.9k $41.5k | First filing |
| TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio | 31.5k $41.0k | Reduced -5.7k |
| CWM, LLC 0.00% of their portfolio | 30.6k $40.0k | Reduced -1.5k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 29.6k $38.4k | Unchanged |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 28.5k $37.1k | Added +14.5k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 25.5k $33.1k | Reduced -11.2k |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 25.2k $32.7k | Added +35 |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 25.0k $32.5k | Added +24.2k |
| XPONANCE LLC 0.00% of their portfolio | 23.4k $30.4k | Unchanged |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 22.4k $29.1k | Added +6.9k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 21.6k $28.0k | Added +1.1k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 20.7k $27.0k | Added +388 |
| Sterling Capital Management LLC 0.00% of their portfolio | 20.7k $26.9k | Added +12.6k |
| GTS SECURITIES LLC 0.00% of their portfolio | 20.5k $26.7k | New |