STANDARD BIOTOOLS INC LAB
COM · Common Stock · CUSIP 34385P108
Company in South San Francisco, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBoston, MA
- Founded1999
- Websitestandardbio.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($771.3k this quarter). Holder counts are more reliable. Shares outstanding: 378.9m as of 2024-04-10, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.71. Options: 5 managers hold calls ($3.1m notional), 3 hold puts ($1.1k).
Trends to Q1 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 66 |
| Q4 2022 | 68 |
| Q1 2023 | 69 |
| Q2 2023 | 67 |
| Q3 2023 | 73 |
| Q4 2023 | 87 |
| Q1 2024 | 146 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 29 | 32 |
| Q1 2023 | 29 | 28 |
| Q2 2023 | 24 | 39 |
| Q3 2023 | 31 | 28 |
| Q4 2023 | 48 | 26 |
| Q1 2024 | 120 | 24 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2023 | $28.8k | $61.8k | 2.14 |
| Q3 2023 | $82.9k | $98.9k | 1.19 |
| Q4 2023 | $29.8k | $663 | 0.02 |
| Q1 2024 | $3.1m | $1.1k | 0.00 |
Biggest buyers
| Casdin Capital, LLC | Added | +60.7m |
| VIKING GLOBAL INVESTORS LP | New | +58.7m |
| MORGAN STANLEY | Added | +15.0m |
| ARK Investment Management LLC | New | +13.0m |
| MILLENNIUM MANAGEMENT LLC | Added | +12.9m |
| VANGUARD GROUP INC | Added | +8.9m |
| Amova Asset Management Americas, Inc. | New | +8.9m |
| Sumitomo Mitsui Trust Group, Inc. | New | +8.9m |
| Tikvah Management LLC | New | +6.6m |
| BlackRock Inc. | Added | +3.8m |
Biggest sellers
| Caligan Partners LP | Sold out | -7.0m |
| Hollow Brook Wealth Management LLC | Sold out | -1.9m |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | -476.2k |
| HighTower Advisors, LLC | Reduced | -116.6k |
| 683 Capital Management, LLC | Sold out | -87.2k |
| Indaba Capital Management, L.P. | Reduced | -83.2k |
| CITADEL ADVISORS LLC | Sold out | -71.3k |
| PRIMECAP MANAGEMENT CO/CA/ | Reduced | -32.1k |
| Dynamic Technology Lab Private Ltd | Sold out | -24.7k |
| Bank of New York Mellon Corp | Reduced | -22.5k |
Biggest calls
| GROUP ONE TRADING LLC | Added | $1.3m474.9k shares |
| SIMPLEX TRADING, LLC | New | $859.0k317.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $826.3k304.9k shares |
| CITADEL ADVISORS LLC | Added | $138.5k51.1k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $1.1k400 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | New | $0200 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Casdin Capital, LLC
13D · may seek influence
-0.3 pts · filed 2026-06-09
Stated purposeItem 4 of the Schedule 13D amendment filed on November 28, 2025 is hereby supplemented by the addition of the following: On June 6, 2026, the Issuer, Treeline Biosciences, Inc., a Delaware corporation (the "Company"), and Siri Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Issuer ("Merger Sub"), entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"), pursuant to which, among other matters, and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, Merger Sub will merge with and into the Company, with the Company continuing as a wholly owned subsidiary of the Issuer and the surviving corporation of the merger (the "Merger"). Upon the terms and subject to the conditions set forth in the Merg… Full filing |
23.9% |
VIKING GLOBAL INVESTORS LP
13D · may seek influence
no change · filed 2026-06-12
Stated purposeThe response to Item 3 of this Schedule 13D is incorporated by reference herein. On June 6, 2026, the Issuer, Treeline Biosciences, Inc., a Delaware corporation ("Treeline"), and Siri Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Issuer ("Merger Sub"), entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"), pursuant to which, among other matters, and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, Merger Sub will merge with and into Treeline, with Treeline continuing as a wholly owned subsidiary of the Issuer and the surviving corporation of the merger (the "Merger"). Upon the terms and subject to the conditions set forth in the Merger Agreement, at the effective time of the Merger… Full filing |
15.0% |
| MAK CAPITAL ONE LLC 13G · passive investor filed 2026-08-14 | 7.3% |
| MAK Capital Fund LP 13G · passive investor +1.5 pts · filed 2026-05-15 | 6.7% |
| Long Focus Capital Management, LLC 13G · institution new · filed 2026-08-14 | 6.0% |
Fell to 5% or below in the last year: BlackRock, Inc. (2.0%, 2026-07-30)
Insider purchases and sales in Q1 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 0 | — | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 3 | $2.8m | 0 | — | — |
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 1 | $646.2k | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-03-05 | Casdin Partners GP, LLC +8 Director | Bought | $3.7k1.4k shares |
| 2024-03-04 | Casdin Partners GP, LLC +8 Director | Bought | $642.5k250.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2024
| Manager | Shares | Change |
|---|---|---|
| Casdin Capital, LLC 12.48% of their portfolio | 61.9m $167.8m | Added +60.7m |
| VIKING GLOBAL INVESTORS LP 0.59% of their portfolio | 58.7m $158.9m | New |
| MORGAN STANLEY 0.00% of their portfolio | 22.9m $61.9m | Added +15.0m |
| MILLENNIUM MANAGEMENT LLC 0.03% of their portfolio | 14.4m $39.0m | Added +12.9m |
| ARK Investment Management LLC 0.24% of their portfolio | 13.0m $35.3m | New |
| VANGUARD GROUP INC 0.00% of their portfolio | 13.0m $35.3m | Added +8.9m |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 8.9m $24.0m | New |
| Amova Asset Management Americas, Inc. 0.24% of their portfolio | 8.9m $24.0m | New |
| Indaba Capital Management, L.P. 13.03% of their portfolio | 7.4m $20.0m | Reduced -83.2k |
| Tikvah Management LLC 5.56% of their portfolio | 6.6m $17.8m | New |
| BlackRock Inc. 0.00% of their portfolio | 5.5m $14.8m | Added +3.8m |
| Balyasny Asset Management L.P. 0.03% of their portfolio | 4.8m $13.1m | Added +2.7m |
| NEUBERGER BERMAN GROUP LLC 0.01% of their portfolio | 4.7m $12.9m | Added +379.1k |
| BARCLAYS PLC 0.00% of their portfolio | 4.0m $10.7m | Added +3.8m |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 3.3m $8.9m | Added +3.1m |
| PRIMECAP MANAGEMENT CO/CA/ 0.01% of their portfolio | 3.0m $8.2m | Reduced -32.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.7m $7.3m | Added +1.9m |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 2.1m $5.7m | Added +1.9m |
| Nan Fung Group Holdings Ltd 4.73% of their portfolio | 1.9m $5.1m | New |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 1.7m $4.7m | New |
| Parkman Healthcare Partners LLC 0.56% of their portfolio | 1.7m $4.5m | Added +1.1m |
| Slate Path Capital LP 0.09% of their portfolio | 1.6m $4.4m | New |
| Magnetar Financial LLC 0.09% of their portfolio | 1.5m $4.1m | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 1.4m $3.7m | Added +1.1m |
| STATE STREET CORP 0.00% of their portfolio | 1.3m $3.6m | Added +1.0m |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 1.3m $3.4m | New |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 1.3m $3.4m | Added +214.3k |
| Schonfeld Strategic Advisors LLC 0.03% of their portfolio | 1.2m $3.3m | Added +1.0m |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.2m $3.2m | Added +896.5k |
| NEEDHAM INVESTMENT MANAGEMENT LLC 0.28% of their portfolio | 1.1m $3.0m | Unchanged |
| Price Jennifer C. 2.51% of their portfolio | 980.1k $2.7m | Unchanged |
| GAGNON SECURITIES LLC 0.55% of their portfolio | 855.1k $2.3m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 784.9k $2.1m | Added +583.8k |
| Meteora Capital, LLC 0.31% of their portfolio | 677.1k $1.8m | New |
| CITIGROUP INC 0.00% of their portfolio | 676.2k $1.8m | Added +352.6k |
| Gagnon Advisors, LLC 1.58% of their portfolio | 672.3k $1.8m | New |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 646.9k $1.8m | Added +490.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 636.3k $1.7m | Added +554.8k |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 578.4k $1.6m | Added +512.9k |
| PARADIGM CAPITAL MANAGEMENT INC/NY 0.07% of their portfolio | 550.0k $1.5m | Added +500.0k |
| HRT FINANCIAL LP 0.01% of their portfolio | 507.4k $1.4m | New |
| Zweig-DiMenna Associates LLC 0.12% of their portfolio | 505.5k $1.4m | New |
| UBS Group AG 0.00% of their portfolio | 483.9k $1.3m | Added +462.7k |
| Bradley & Co. Private Wealth Management, LLC 0.98% of their portfolio | 447.9k $1.2m | Added +397.9k |
| RBF Capital, LLC 0.07% of their portfolio | 441.6k $1.2m | New |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 441.2k $1.2m | Added +413.9k |
| Swiss National Bank 0.00% of their portfolio | 428.7k $1.2m | New |
| Allianz Asset Management GmbH 0.00% of their portfolio | 426.2k $1.2m | New |
| Intellectus Partners, LLC 0.30% of their portfolio | 423.5k $1.1m | Added +360.8k |
| Redmile Group, LLC 0.04% of their portfolio | 411.6k $1.1m | New |
| BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio | 331.7k $898.8k | Reduced -476.2k |
| JOHNSON & JOHNSON 0.02% of their portfolio | 312.0k $845.4k | New |
| Man Group plc 0.00% of their portfolio | 310.6k $841.7k | Added +112.4k |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 304.5k $825.0k | Added +232.5k |
| Point72 Asia (Singapore) Pte. Ltd. 0.21% of their portfolio | 303.2k $821.7k | New |
| Laurion Capital Management LP 0.02% of their portfolio | 300.0k $813.0k | Unchanged |
| COWEN AND COMPANY, LLC 0.03% of their portfolio | 274.4k $743.7k | New |
| Driehaus Capital Management LLC 0.01% of their portfolio | 236.5k $640.9k | New |
| MIRABELLA FINANCIAL SERVICES LLP 0.04% of their portfolio | 215.5k $584.1k | New |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 212.0k $574.5k | Unchanged |
| Jump Financial, LLC 0.02% of their portfolio | 211.9k $574.2k | Added +141.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 195.1k $528.8k | New |
| Legal & General Group Plc 0.00% of their portfolio | 192.8k $522.4k | New |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 159.7k $432.7k | Added +29.0k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 156.7k $424.7k | New |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 156.2k $423.0k | Added +113.3k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 142.3k $385.6k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 132.8k $359.8k | Added +96.4k |
| SILVERBACK ASSET MANAGEMENT LLC 0.05% of their portfolio | 125.0k $338.8k | Unchanged |
| Jefferies Financial Group Inc. 0.01% of their portfolio | 119.4k $323.6k | Added +63.0k |
| Brevan Howard Capital Management LP 0.03% of their portfolio | 116.9k $316.8k | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 111.6k $302.4k | Added +80.4k |
| Y-Intercept (Hong Kong) Ltd 0.02% of their portfolio | 110.9k $300.5k | Added +71.4k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 104.1k $282.0k | New |
| LUMINUS MANAGEMENT LLC 0.15% of their portfolio | 95.0k $257.4k | New |
| FourWorld Capital Management LLC 0.23% of their portfolio | 91.7k $248.5k | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 87.6k $237.4k | Reduced -22.5k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 81.6k $221.2k | Added +58.1k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.00% of their portfolio | 78.1k $211.6k | New |
| HighTower Advisors, LLC 0.00% of their portfolio | 76.1k $206.0k | Reduced -116.6k |
| SACHEM HILL LLC 0.05% of their portfolio | 74.2k $201.1k | New |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 72.1k $195.6k | New |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 69.2k $187.7k | Reduced -2.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 68.9k $187.0k | Added +42.1k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 63.4k $171.9k | New |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 59.7k $161.7k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 58.4k $158.0k | Added +6.2k |
| CTC Alternative Strategies, Ltd. 0.10% of their portfolio | 57.6k $156.1k | New |
| Polar Capital Holdings Plc 0.00% of their portfolio | 56.6k $153.3k | Unchanged |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 49.0k $132.8k | New |
| Engineers Gate Manager LP 0.00% of their portfolio | 45.4k $123.0k | Added +31.0k |
| Corvex Management LP 0.01% of their portfolio | 44.4k $120.3k | New |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 0.00% of their portfolio | 42.6k $115.0k | New |
| OMERS ADMINISTRATION Corp 0.00% of their portfolio | 37.4k $101.4k | New |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 36.9k $100.0k | Added +26.0k |
| DRW Securities, LLC 0.00% of their portfolio | 30.6k $82.9k | New |
| SEI INVESTMENTS CO 0.00% of their portfolio | 30.3k $82.0k | Reduced -518 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 26.8k $72.6k | Added +17.5k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 26.4k $71.5k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 26.1k $71.0k | New |