STANDARD BIOTOOLS INC LAB
COM · Common Stock · CUSIP 34385P108
Company in South San Francisco, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBoston, MA
- Founded1999
- Websitestandardbio.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($17.9k this quarter). Holder counts are more reliable. Shares outstanding: 79.4m as of 2023-11-03, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.90. Options: 4 managers hold calls ($82.9k notional), 4 hold puts ($98.9k).
Trends to Q3 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 66 |
| Q4 2022 | 68 |
| Q1 2023 | 69 |
| Q2 2023 | 67 |
| Q3 2023 | 73 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 29 | 32 |
| Q1 2023 | 29 | 28 |
| Q2 2023 | 24 | 39 |
| Q3 2023 | 31 | 28 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2022 | $36.5k | $107.0k | 2.93 |
| Q1 2023 | $21.6k | $254.6k | 11.76 |
| Q2 2023 | $28.8k | $61.8k | 2.14 |
| Q3 2023 | $82.9k | $98.9k | 1.19 |
Biggest buyers
| Hollow Brook Wealth Management LLC | New | +1.8m |
| MORGAN STANLEY | Added | +1.4m |
| Balyasny Asset Management L.P. | Added | +595.0k |
| Parkman Healthcare Partners LLC | New | +500.0k |
| Informed Momentum Co LLC | New | +474.0k |
| CITIGROUP INC | New | +189.8k |
| Schonfeld Strategic Advisors LLC | New | +143.0k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +69.9k |
| Jefferies Financial Group Inc. | New | +56.4k |
| BARCLAYS PLC | New | +48.2k |
Biggest sellers
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | -1.1m |
| Caligan Partners LP | Reduced | -845.5k |
| NEEDHAM INVESTMENT MANAGEMENT LLC | Reduced | -810.0k |
| HighTower Advisors, LLC | Reduced | -593.6k |
| D. E. Shaw & Co., Inc. | Reduced | -199.1k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -157.7k |
| SILVERBACK ASSET MANAGEMENT LLC | Reduced | -150.0k |
| PRIMECAP MANAGEMENT CO/CA/ | Reduced | -137.8k |
| TUDOR INVESTMENT CORP ET AL | Sold out | -85.1k |
| BlackRock Inc. | Reduced | -72.1k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $29.9k10.3k shares |
| GROUP ONE TRADING LLC | Added | $29.0k10.0k shares |
| SIMPLEX TRADING, LLC | Added | $24.0k8.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| GROUP ONE TRADING LLC | Reduced | $53.1k18.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $45.5k15.7k shares |
| CITADEL ADVISORS LLC | New | $290100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Casdin Capital, LLC
13D · may seek influence
-0.3 pts · filed 2026-06-09
Stated purposeItem 4 of the Schedule 13D amendment filed on November 28, 2025 is hereby supplemented by the addition of the following: On June 6, 2026, the Issuer, Treeline Biosciences, Inc., a Delaware corporation (the "Company"), and Siri Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Issuer ("Merger Sub"), entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"), pursuant to which, among other matters, and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, Merger Sub will merge with and into the Company, with the Company continuing as a wholly owned subsidiary of the Issuer and the surviving corporation of the merger (the "Merger"). Upon the terms and subject to the conditions set forth in the Merg… Full filing |
23.9% |
VIKING GLOBAL INVESTORS LP
13D · may seek influence
no change · filed 2026-06-12
Stated purposeThe response to Item 3 of this Schedule 13D is incorporated by reference herein. On June 6, 2026, the Issuer, Treeline Biosciences, Inc., a Delaware corporation ("Treeline"), and Siri Merger Sub, Inc., a Delaware corporation and a wholly owned subsidiary of the Issuer ("Merger Sub"), entered into an Agreement and Plan of Merger and Reorganization (the "Merger Agreement"), pursuant to which, among other matters, and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, Merger Sub will merge with and into Treeline, with Treeline continuing as a wholly owned subsidiary of the Issuer and the surviving corporation of the merger (the "Merger"). Upon the terms and subject to the conditions set forth in the Merger Agreement, at the effective time of the Merger… Full filing |
15.0% |
| MAK CAPITAL ONE LLC 13G · passive investor filed 2026-08-14 | 7.3% |
| MAK Capital Fund LP 13G · passive investor +1.5 pts · filed 2026-05-15 | 6.7% |
| Long Focus Capital Management, LLC 13G · institution new · filed 2026-08-14 | 6.0% |
Fell to 5% or below in the last year: BlackRock, Inc. (2.0%, 2026-07-30)
Insider purchases and sales in Q3 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2021 | 0 | — | 0 | — | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 0 | — | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 3 | $2.8m | 0 | — | — |
| Q3 2023 | 0 | — | 0 | — | — |
None reported in Q3 2023.
Holders, Q3 2023
| Manager | Shares | Change |
|---|---|---|
| Caligan Partners LP 11.31% of their portfolio | 7.6m $22.1m | Reduced -845.5k |
| Indaba Capital Management, L.P. 6.36% of their portfolio | 7.4m $21.6m | Unchanged |
| NEUBERGER BERMAN GROUP LLC 0.01% of their portfolio | 4.5m $13.2m | Added +38.6k |
| MORGAN STANLEY 0.00% of their portfolio | 4.5m $12.9m | Added +1.4m |
| VANGUARD GROUP INC 0.00% of their portfolio | 4.0m $11.5m | Added +31.6k |
| PRIMECAP MANAGEMENT CO/CA/ 0.01% of their portfolio | 3.1m $8.9m | Reduced -137.8k |
| Balyasny Asset Management L.P. 0.02% of their portfolio | 2.7m $7.8m | Added +595.0k |
| Hollow Brook Wealth Management LLC 2.16% of their portfolio | 1.8m $5.2m | New |
| BlackRock Inc. 0.00% of their portfolio | 1.4m $4.0m | Reduced -72.1k |
| NEEDHAM INVESTMENT MANAGEMENT LLC 0.60% of their portfolio | 1.2m $3.6m | Reduced -810.0k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.11% of their portfolio | 1.2m $3.5m | Reduced -1.1m |
| Casdin Capital, LLC 0.39% of their portfolio | 1.2m $3.5m | Unchanged |
| Price Jennifer C. 1.64% of their portfolio | 980.1k $2.8m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 757.8k $2.2m | Added +69.9k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 613.4k $1.8m | Reduced -11.9k |
| Parkman Healthcare Partners LLC 0.27% of their portfolio | 500.0k $1.4m | New |
| Informed Momentum Co LLC 0.27% of their portfolio | 474.0k $1.4m | New |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 428.6k $1.2m | Reduced -157.7k |
| SILVERBACK ASSET MANAGEMENT LLC 0.12% of their portfolio | 300.0k $870.0k | Reduced -150.0k |
| STATE STREET CORP 0.00% of their portfolio | 279.5k $810.7k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 212.0k $614.8k | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 202.2k $586.5k | Added +27.5k |
| HighTower Advisors, LLC 0.00% of their portfolio | 192.7k $559.0k | Reduced -593.6k |
| CITIGROUP INC 0.00% of their portfolio | 189.8k $550.4k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 144.6k $419.3k | Reduced -199.1k |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 143.0k $414.7k | New |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 131.8k $382.1k | Added +728 |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 113.5k $329.2k | Added +33.5k |
| Polar Capital Holdings Plc 0.00% of their portfolio | 100.0k $290.0k | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 97.7k $283.3k | Reduced -2.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 96.2k $279.1k | Added +25.0k |
| Intellectus Partners, LLC 0.06% of their portfolio | 62.8k $182.0k | Unchanged |
| Jefferies Financial Group Inc. 0.00% of their portfolio | 56.4k $163.6k | New |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 54.4k $157.8k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 50.2k $146.0k | Reduced -13.1k |
| Bradley & Co. Private Wealth Management, LLC 0.15% of their portfolio | 50.0k $145.0k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 48.2k $139.8k | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 47.6k $138.0k | Added +20.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 38.4k $112.0k | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 35.6k $103.3k | Reduced -2.9k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 34.6k $100.3k | New |
| SEI INVESTMENTS CO 0.00% of their portfolio | 33.8k $98.0k | Added +1.9k |
| Jump Financial, LLC 0.00% of their portfolio | 32.5k $94.1k | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 31.2k $90.5k | Unchanged |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 30.1k $87.0k | Unchanged |
| EverSource Wealth Advisors, LLC 0.01% of their portfolio | 27.8k $80.6k | Unchanged |
| ALGERT GLOBAL LLC 0.00% of their portfolio | 26.1k $75.7k | Unchanged |
| MARSHALL WACE, LLP 0.00% of their portfolio | 23.5k $68.1k | Added +7.3k |
| FREEDOM WEALTH ALLIANCE, LLC 0.10% of their portfolio | 20.4k $59.1k | New |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 19.9k $57.7k | Reduced -10.2k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 19.1k $55.3k | New |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 17.6k $50.0k | New |
| MEYER HANDELMAN CO 0.00% of their portfolio | 17.5k $50.8k | Unchanged |
| Engineers Gate Manager LP 0.00% of their portfolio | 16.3k $47.4k | Reduced -1.2k |
| UBS Group AG 0.00% of their portfolio | 15.6k $45.3k | Reduced -3.2k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 15.0k $43.5k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 10.4k $30.2k | Added +9.9k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 9.5k $27.6k | Reduced -214 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 6.4k $18.6k | Added +485 |
| Cubist Systematic Strategies, LLC 0.00% of their portfolio | 6.2k $17.9k | Reduced -9.6k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 2.9k $8.4k | Unchanged |
| Park Place Capital Corp 0.00% of their portfolio | 2.8k $8.1k | Unchanged |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 1.4k $4.0k | Reduced -7.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.3k $3.8k | Unchanged |
| COMERICA BANK 0.00% of their portfolio | 1.2k $3.4k | New |
| Sandy Spring Bank 0.00% of their portfolio | 1.0k $2.9k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 947 $2.7k | Added +64 |
| Global Retirement Partners, LLC 0.00% of their portfolio | 880 $1.8k | Unchanged |
| Allworth Financial LP 0.00% of their portfolio | 845 $2.5k | Added +145 |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 498 $1.4k | New |
| FMR LLC 0.00% of their portfolio | 51 $148 | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 1 $3 | Unchanged |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |