FATE THERAPEUTICS INC FATE
COM · Common Stock · CUSIP 31189P102 · ISIN US31189P1021
A clinical-stage biopharmaceutical company in San Diego, United States
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSan Diego, CA
- Websitefatetherapeutics.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($46.8k this quarter). Holder counts are more reliable. Shares outstanding: 115.3m as of 2025-08-05, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.12. Options: 6 managers hold calls ($263.7k notional), 4 hold puts ($40.4k).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 240 |
| Q4 2022 | 229 |
| Q1 2023 | 184 |
| Q2 2023 | 190 |
| Q3 2023 | 172 |
| Q4 2023 | 160 |
| Q1 2024 | 168 |
| Q2 2024 | 184 |
| Q3 2024 | 165 |
| Q4 2024 | 160 |
| Q1 2025 | 133 |
| Q2 2025 | 140 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 80 | 93 |
| Q4 2023 | 65 | 96 |
| Q1 2024 | 87 | 82 |
| Q2 2024 | 91 | 72 |
| Q3 2024 | 58 | 96 |
| Q4 2024 | 73 | 87 |
| Q1 2025 | 56 | 81 |
| Q2 2025 | 69 | 62 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2024 | $238.9k | $34.5k | 0.14 |
| Q4 2024 | $91.5k | $39.4k | 0.43 |
| Q1 2025 | $63.7k | $6.2k | 0.10 |
| Q2 2025 | $263.7k | $40.4k | 0.15 |
Biggest buyers
| MILLENNIUM MANAGEMENT LLC | Added | +564.8k |
| JANE STREET GROUP, LLC | Added | +402.1k |
| ROYAL BANK OF CANADA | Added | +291.3k |
| AQR CAPITAL MANAGEMENT LLC | Added | +261.2k |
| GSA CAPITAL PARTNERS LLP | New | +256.7k |
| CITADEL ADVISORS LLC | Added | +254.7k |
| RENAISSANCE TECHNOLOGIES LLC | New | +214.5k |
| MORGAN STANLEY | Added | +193.5k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +159.6k |
| BlackRock, Inc. | Added | +128.7k |
Biggest sellers
| Schonfeld Strategic Advisors LLC | Reduced | -6.9m |
| JPMORGAN CHASE & CO | Reduced | -3.3m |
| ORBIMED ADVISORS LLC | Sold out | -1.7m |
| VANGUARD GROUP INC | Reduced | -1.5m |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Reduced | -989.6k |
| BAKER BROS. ADVISORS LP | Reduced | -773.4k |
| Woodline Partners LP | Reduced | -711.5k |
| Integral Health Asset Management, LLC | Sold out | -700.0k |
| UBS Group AG | Reduced | -588.4k |
| Monaco Asset Management SAM | Reduced | -474.7k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $110.1k98.3k shares |
| CITADEL ADVISORS LLC | Added | $68.4k61.1k shares |
| GROUP ONE TRADING LLC | Added | $58.8k52.5k shares |
| LPL Financial LLC | Reduced | $22.4k20.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $4.0k4.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| GROUP ONE TRADING LLC | Added | $25.4k22.7k shares |
| CITADEL ADVISORS LLC | Added | $15.0k13.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | Added | $0300 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Redmile Group, LLC 13D · may seek influence no change · filed 2026-04-22 | 14.9% |
Fell to 5% or below in the last year: BlackRock, Inc. (1.9%, 2026-07-08), VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 3 | $59.4k | $27.4k |
| Q4 2023 | 1 | $166.0k | 2 | $64.0k | $64.0k |
| Q1 2024 | 0 | — | 4 | $237.7k | $47.2k |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 1 | $2.7k | $2.7k |
| Q4 2024 | 1 | $668.6k | 1 | $573.9k | — |
| Q1 2025 | 0 | — | 3 | $31.4k | — |
| Q2 2025 | 0 | — | 0 | — | — |
None reported in Q2 2025.
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| Redmile Group, LLC 1.53% of their portfolio | 12.9m $14.4m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 10.8m $12.1m | Added +128.7k |
| VANGUARD GROUP INC 0.00% of their portfolio | 8.8m $9.8m | Reduced -1.5m |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 4.5m $5.1m | Added +254.7k |
| JOHNSON & JOHNSON 1.05% of their portfolio | 3.4m $3.5m | Unchanged |
| Vestal Point Capital, LP 0.15% of their portfolio | 2.5m $2.8m | Reduced -850 |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 2.5m $2.8m | Added +52.7k |
| BAKER BROS. ADVISORS LP 0.03% of their portfolio | 2.5m $2.8m | Reduced -773.4k |
| ACADIAN ASSET MANAGEMENT LLC 0.01% of their portfolio | 2.5m $2.8m | Reduced -13.6k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 2.4m $2.7m | Reduced -153.8k |
| MORGAN STANLEY 0.00% of their portfolio | 2.4m $2.7m | Added +193.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.4m $2.7m | Added +159.6k |
| STATE STREET CORP 0.00% of their portfolio | 2.2m $2.5m | Added +119.1k |
| CITIGROUP INC 0.00% of their portfolio | 1.9m $2.1m | Reduced -33.4k |
| TANG CAPITAL MANAGEMENT LLC 0.11% of their portfolio | 1.9m $2.1m | Unchanged |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.01% of their portfolio | 1.2m $1.4m | Reduced -989.6k |
| UBS Group AG 0.00% of their portfolio | 962.7k $1.1m | Reduced -588.4k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 930.8k $1.0m | Reduced -6.9m |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 879.7k $985.3k | Added +564.8k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 846.2k $947.8k | Added +261.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 844.4k $945.7k | Added +49.4k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 733.9k $822.0k | Added +30.1k |
| Woodline Partners LP 0.00% of their portfolio | 712.6k $798.2k | Reduced -711.5k |
| Monaco Asset Management SAM 0.29% of their portfolio | 675.0k $756.0k | Reduced -474.7k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 493.1k $552.3k | Reduced -293.9k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 465.8k $521.7k | Added +402.1k |
| BARCLAYS PLC 0.00% of their portfolio | 453.1k $507.4k | Added +85.8k |
| XTX Topco Ltd 0.02% of their portfolio | 432.3k $484.2k | Reduced -27.0k |
| Bruce & Co., Inc. 0.16% of their portfolio | 429.2k $480.7k | Reduced -120.8k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 339.7k $380.5k | Reduced -71.6k |
| Nuveen, LLC 0.00% of their portfolio | 336.9k $377.3k | Reduced -42.2k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 299.9k $336.0k | Added +291.3k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 290.7k $325.5k | Reduced -1.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 289.2k $323.9k | Added +111.9k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 287.4k $321.9k | Reduced -54.8k |
| GSA CAPITAL PARTNERS LLP 0.02% of their portfolio | 256.7k $288.0k | New |
| Invesco Ltd. 0.00% of their portfolio | 255.4k $286.0k | Added +41.9k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 228.4k $255.8k | Reduced -13.5k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 214.5k $240.2k | New |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 212.3k $237.8k | Reduced -90.6k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 187.7k $210.2k | Added +41.1k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 155.9k $174.6k | Added +5.6k |
| National Philanthropic Trust 0.00% of their portfolio | 125.0k $140.0k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 122.2k $136.9k | Added +19.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 122.1k $136.8k | Reduced -266.3k |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 117.1k $131.1k | Added +42.6k |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 113.7k $127.3k | Reduced -49.0k |
| Cubist Systematic Strategies, LLC 0.00% of their portfolio | 111.5k $124.9k | New |
| Privium Fund Management B.V. 0.03% of their portfolio | 111.1k $126.6k | Added +2.1k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 103.0k $117.9k | Reduced -6.4k |
| Virtu Financial LLC 0.01% of their portfolio | 100.9k $113.0k | New |
| Graham Capital Management, L.P. 0.00% of their portfolio | 85.6k $95.9k | Reduced -54.4k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 73.4k $82.2k | Reduced -5.0k |
| Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio | 71.4k $79.9k | Added +28.3k |
| Leo Wealth, LLC 0.01% of their portfolio | 70.4k $78.9k | Unchanged |
| MetLife Investment Management, LLC 0.00% of their portfolio | 68.0k $76.1k | New |
| SEI INVESTMENTS CO 0.00% of their portfolio | 67.7k $75.9k | Reduced -122 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 58.6k $65.6k | Reduced -3.3m |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 57.3k $64.2k | Reduced -2.5k |
| SG Americas Securities, LLC 0.00% of their portfolio | 52.6k $59.0k | Added +18.1k |
| Headlands Technologies LLC 0.01% of their portfolio | 49.6k $55.5k | New |
| CWM, LLC 0.00% of their portfolio | 49.4k $55.0k | Added +8.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 46.9k $53.0k | Added +8.8k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 41.1k $46.1k | Added +4.0k |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 38.0k $42.0k | Added +23.6k |
| HighTower Advisors, LLC 0.00% of their portfolio | 37.2k $41.7k | Added +27.0k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 37.1k $41.0k | Reduced -52.2k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 35.3k $39.6k | Added +5.4k |
| FMR LLC 0.00% of their portfolio | 34.1k $38.2k | Reduced -23.8k |
| Focus Partners Wealth 0.00% of their portfolio | 32.7k $36.6k | Added +2.5k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 32.1k $36.0k | Reduced -27.2k |
| Cerity Partners LLC 0.00% of their portfolio | 31.0k $32.9k | Added +1.1k |
| Parcion Private Wealth LLC 0.00% of their portfolio | 30.8k $34.5k | Added +392 |
| Corient Private Wealth LP 0.00% of their portfolio | 29.7k $33.3k | Added +75 |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 28.0k $31.4k | Unchanged |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 28.0k $31.4k | Unchanged |
| ProShare Advisors LLC 0.00% of their portfolio | 26.6k $29.8k | Reduced -171 |
| FPC INVESTMENT ADVISORY, INC. 0.02% of their portfolio | 26.5k $31.0k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 25.0k $28.0k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 23.8k $26.6k | Added +6.9k |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 23.0k $25.8k | Added +179 |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 22.8k $26.0k | Added +2.4k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 21.8k $24.4k | Reduced -51.5k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 20.8k $23.3k | Unchanged |
| Quinn Opportunity Partners LLC 0.00% of their portfolio | 20.0k $22.4k | New |
| CAPTRUST FINANCIAL ADVISORS 0.00% of their portfolio | 19.6k $22.0k | Added +3.2k |
| TITLEIST ASSET MANAGEMENT, LLC 0.00% of their portfolio | 19.0k $21.3k | New |
| Parametrica Management Ltd 0.04% of their portfolio | 18.5k $20.7k | Unchanged |
| Grassi Investment Management 0.00% of their portfolio | 18.0k $20.0k | Unchanged |
| Squarepoint Ops LLC 0.00% of their portfolio | 17.8k $19.9k | New |
| TIAA TRUST, NATIONAL ASSOCIATION 0.00% of their portfolio | 17.6k $19.7k | Unchanged |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 16.6k $18.5k | Reduced -62.8k |
| Pallas Capital Advisors LLC 0.00% of their portfolio | 15.3k $17.2k | Added +1.1k |
| LPL Financial LLC 0.00% of their portfolio | 13.9k $15.6k | Reduced -76.6k |
| CIBC WORLD MARKETS CORP 0.00% of their portfolio | 13.4k $15.0k | Reduced -8.8k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 12.8k $14.3k | Added +898 |
| Narwhal Capital Management 0.00% of their portfolio | 12.7k $14.2k | New |
| HBK Sorce Advisory LLC 0.00% of their portfolio | 12.1k $13.6k | New |
| Mariner, LLC 0.00% of their portfolio | 11.5k $12.9k | New |
| Point72 (DIFC) Ltd 0.00% of their portfolio | 10.5k $11.7k | New |