FATE THERAPEUTICS INC FATE
COM · Common Stock · CUSIP 31189P102 · ISIN US31189P1021
A clinical-stage biopharmaceutical company in San Diego, United States
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSan Diego, CA
- Websitefatetherapeutics.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($160.5k this quarter). Holder counts are more reliable. Shares outstanding: 114.6m as of 2025-02-25, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.64. Options: 5 managers hold calls ($91.5k notional), 4 hold puts ($39.4k).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 240 |
| Q4 2022 | 229 |
| Q1 2023 | 184 |
| Q2 2023 | 190 |
| Q3 2023 | 172 |
| Q4 2023 | 160 |
| Q1 2024 | 168 |
| Q2 2024 | 184 |
| Q3 2024 | 165 |
| Q4 2024 | 160 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2023 | 94 | 121 |
| Q2 2023 | 92 | 83 |
| Q3 2023 | 80 | 93 |
| Q4 2023 | 65 | 96 |
| Q1 2024 | 87 | 82 |
| Q2 2024 | 91 | 72 |
| Q3 2024 | 58 | 96 |
| Q4 2024 | 73 | 87 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $1.7m | $399.5k | 0.24 |
| Q2 2024 | $115.5k | $47.9k | 0.41 |
| Q3 2024 | $238.9k | $34.5k | 0.14 |
| Q4 2024 | $91.5k | $39.4k | 0.43 |
Biggest buyers
| EcoR1 Capital, LLC | New | +3.0m |
| TANG CAPITAL MANAGEMENT LLC | Added | +1.2m |
| Walleye Capital LLC | Added | +1.0m |
| Cerity Partners LLC | Added | +806.8k |
| Vestal Point Capital, LP | Added | +780.0k |
| CITIGROUP INC | Added | +707.7k |
| UBS Group AG | Added | +699.1k |
| MARSHALL WACE, LLP | New | +512.6k |
| BlackRock, Inc. | Added | +468.3k |
| SPHERA FUNDS MANAGEMENT LTD. | New | +397.2k |
Biggest sellers
| Deep Track Capital, LP | Sold out | -5.6m |
| Boxer Capital, LLC | Sold out | -5.0m |
| STATE STREET CORP | Reduced | -3.0m |
| Assenagon Asset Management S.A. | Reduced | -2.1m |
| JPMORGAN CHASE & CO | Reduced | -2.0m |
| D. E. Shaw & Co., Inc. | Reduced | -1.8m |
| Woodline Partners LP | Reduced | -1.6m |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Sold out | -870.0k |
| BANK OF AMERICA CORP /DE/ | Reduced | -550.1k |
| GCM Grosvenor Holdings, LLC | Sold out | -495.9k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $42.1k25.5k shares |
| CITADEL ADVISORS LLC | Added | $26.1k15.8k shares |
| SIMPLEX TRADING, LLC | Added | $21.0k13.0k shares |
| GROUP ONE TRADING LLC | Reduced | $2.3k1.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $26.2k15.9k shares |
| GROUP ONE TRADING LLC | New | $13.2k8.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| SIMPLEX TRADING, LLC | Reduced | $0400 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Redmile Group, LLC 13D · may seek influence no change · filed 2026-04-22 | 14.9% |
Fell to 5% or below in the last year: BlackRock, Inc. (1.9%, 2026-07-08), VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 1 | $698.1k | 6 | $455.6k | — |
| Q2 2023 | 1 | $1.9m | 3 | $1.8m | $36.0k |
| Q3 2023 | 0 | — | 3 | $59.4k | $27.4k |
| Q4 2023 | 1 | $166.0k | 2 | $64.0k | $64.0k |
| Q1 2024 | 0 | — | 4 | $237.7k | $47.2k |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 1 | $2.7k | $2.7k |
| Q4 2024 | 1 | $668.6k | 1 | $573.9k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-12-20 | Redmile Group, LLC +1 Director · See Footnote | Bought | $668.6k398.0k shares |
| 2024-12-20 | Redmile Group, LLC +1 Director · See Footnote | Sold | $573.9k341.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| Redmile Group, LLC 1.48% of their portfolio | 12.9m $21.2m | Reduced -296.1k |
| BlackRock, Inc. 0.00% of their portfolio | 10.9m $18.1m | Added +468.3k |
| VANGUARD GROUP INC 0.00% of their portfolio | 10.3m $17.0m | Reduced -71.1k |
| Bellevue Group AG 0.15% of their portfolio | 4.8m $8.0m | Unchanged |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 4.4m $7.2m | Added +100.2k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.11% of their portfolio | 3.6m $5.9m | Unchanged |
| JOHNSON & JOHNSON 1.44% of their portfolio | 3.4m $5.6m | Unchanged |
| BAKER BROS. ADVISORS LP 0.06% of their portfolio | 3.3m $5.4m | Added +260.6k |
| EcoR1 Capital, LLC 0.20% of their portfolio | 3.0m $5.0m | New |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 2.9m $4.8m | Added +279.4k |
| MORGAN STANLEY 0.00% of their portfolio | 2.8m $4.7m | Reduced -241.2k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 2.5m $4.1m | Reduced -347.0k |
| Vestal Point Capital, LP 0.24% of their portfolio | 2.5m $4.1m | Added +780.0k |
| STATE STREET CORP 0.00% of their portfolio | 2.2m $3.7m | Reduced -3.0m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.2m $3.7m | Reduced -31.3k |
| TANG CAPITAL MANAGEMENT LLC 0.20% of their portfolio | 1.9m $3.1m | Added +1.2m |
| ORBIMED ADVISORS LLC 0.06% of their portfolio | 1.7m $2.8m | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.7m $2.8m | Reduced -2.0m |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.01% of their portfolio | 1.6m $2.6m | Reduced -913 |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 1.5m $2.5m | Reduced -1.8m |
| ACADIAN ASSET MANAGEMENT LLC 0.01% of their portfolio | 1.5m $2.4m | Reduced -128.3k |
| Woodline Partners LP 0.02% of their portfolio | 1.4m $2.3m | Reduced -1.6m |
| SUPERSTRING CAPITAL MANAGEMENT LP 2.00% of their portfolio | 1.4m $2.3m | Reduced -87.4k |
| UBS Group AG 0.00% of their portfolio | 1.1m $1.8m | Added +699.1k |
| Walleye Capital LLC 0.02% of their portfolio | 1.1m $1.8m | Added +1.0m |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 828.1k $1.4m | Reduced -99.1k |
| Cerity Partners LLC 0.00% of their portfolio | 823.1k $28.2k | Added +806.8k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 805.5k $1.3m | Reduced -9.6k |
| CITIGROUP INC 0.00% of their portfolio | 781.9k $1.3m | Added +707.7k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 770.3k $1.3m | Added +6.5k |
| Integral Health Asset Management, LLC 0.09% of their portfolio | 600.0k $990.0k | Reduced -375.0k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 543.0k $896.0k | Reduced -10.1k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 512.6k $845.9k | New |
| BARCLAYS PLC 0.00% of their portfolio | 416.7k $687.6k | Reduced -7.5k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 413.2k $681.8k | Added +142.6k |
| SPHERA FUNDS MANAGEMENT LTD. 0.12% of their portfolio | 397.2k $655.3k | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 378.6k $624.7k | Added +16.0k |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 372.5k $614.6k | Reduced -2.1m |
| FMR LLC 0.00% of their portfolio | 357.0k $589.0k | Added +129.0k |
| Bruce & Co., Inc. 0.19% of their portfolio | 350.0k $577.5k | Unchanged |
| E Fund Management Co., Ltd. 0.03% of their portfolio | 340.0k $561.0k | Reduced -13.8k |
| Monaco Asset Management SAM 0.24% of their portfolio | 327.7k $540.7k | Added +190.0k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 321.4k $530.3k | Reduced -35.2k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 317.3k $523.5k | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 304.1k $501.8k | Reduced -550.1k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 297.1k $490.2k | Reduced -162.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 293.0k $483.5k | Reduced -6.3k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 287.7k $474.7k | Added +113.6k |
| XTX Topco Ltd 0.03% of their portfolio | 249.8k $412.2k | New |
| BIT Capital GmbH 0.04% of their portfolio | 247.6k $408.5k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 197.7k $326.2k | Added +12.3k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 177.2k $292.3k | Reduced -72.6k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 165.4k $272.8k | Added +14.5k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 159.2k $262.6k | Added +2.2k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 147.6k $243.5k | Added +123.5k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 146.6k $241.9k | Unchanged |
| Jain Global LLC 0.01% of their portfolio | 131.5k $216.9k | First filing |
| National Philanthropic Trust 0.00% of their portfolio | 125.0k $206.2k | Unchanged |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.00% of their portfolio | 118.2k $195.0k | First filing |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 109.4k $178.9k | Added +19.7k |
| Invesco Ltd. 0.00% of their portfolio | 108.9k $179.7k | Added +7.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 107.4k $177.2k | Added +50.7k |
| Aristides Capital LLC 0.05% of their portfolio | 100.6k $165.9k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 92.4k $152.5k | Added +33.3k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 89.8k $148.2k | Added +27.0k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 89.3k $148.0k | Reduced -36.0k |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 88.8k $146.5k | Reduced -46.1k |
| Privium Fund Management B.V. 0.03% of their portfolio | 87.0k $143.6k | Added +37.0k |
| LPL Financial LLC 0.00% of their portfolio | 73.1k $120.6k | New |
| Leo Wealth, LLC 0.01% of their portfolio | 70.4k $116.2k | Added +60.0k |
| Institute for Wealth Management, LLC. 0.01% of their portfolio | 66.9k $110.4k | New |
| ALGERT GLOBAL LLC 0.00% of their portfolio | 65.5k $108.1k | Reduced -101 |
| DARK FOREST CAPITAL MANAGEMENT LP 0.01% of their portfolio | 61.2k $101.0k | Added +34.4k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 57.3k $94.5k | Reduced -6.0k |
| Verition Fund Management LLC 0.00% of their portfolio | 53.6k $88.4k | New |
| Corebridge Financial, Inc. 0.00% of their portfolio | 49.8k $82.1k | Reduced -3.8k |
| Focus Partners Wealth 0.00% of their portfolio | 48.4k $79.8k | Added +24.7k |
| SG Americas Securities, LLC 0.00% of their portfolio | 44.9k $74.0k | Added +10.5k |
| EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio | 42.3k $69.8k | Unchanged |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 39.4k $65.1k | Added +8.5k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 38.4k $63.4k | Reduced -61 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 38.0k $63.0k | Reduced -27.2k |
| Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio | 35.4k $58.3k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 34.3k $56.6k | Added +20.8k |
| ProShare Advisors LLC 0.00% of their portfolio | 33.6k $55.5k | Added +14.7k |
| Point72 Asia (Singapore) Pte. Ltd. 0.01% of their portfolio | 33.1k $54.6k | New |
| Point72 (DIFC) Ltd 0.00% of their portfolio | 31.7k $52.3k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 31.3k $51.6k | Reduced -2.2k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 30.8k $50.8k | Reduced -117.1k |
| Corient Private Wealth LP 0.00% of their portfolio | 29.6k $48.9k | Unchanged |
| HRT FINANCIAL LP 0.00% of their portfolio | 29.2k $48.0k | Reduced -180.0k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 28.0k $46.2k | Unchanged |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 28.0k $46.2k | Unchanged |
| Parcion Private Wealth LLC 0.00% of their portfolio | 28.0k $46.2k | Unchanged |
| Engineers Gate Manager LP 0.00% of their portfolio | 26.5k $43.8k | New |
| FPC INVESTMENT ADVISORY, INC. 0.03% of their portfolio | 26.5k $34.4k | New |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.00% of their portfolio | 25.6k $42.2k | Reduced -6.5k |
| Brevan Howard Capital Management LP 0.00% of their portfolio | 24.6k $40.6k | New |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 24.1k $39.8k | New |
| Graham Capital Management, L.P. 0.00% of their portfolio | 22.3k $36.9k | New |