EYEPOINT PHARMACEUTICALS INC EYPT
COM NEW · Common Stock · CUSIP 30233G209
Company specialising in the application of microelectromechanical systems (MEMS) and nanotechnology to drug delivery
- SectorTechnology
- IndustryLaboratory Analytical Instruments
- HeadquartersWatertown, MA
- Websitepsivida.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($93.3k this quarter). Holder counts are more reliable. Shares outstanding: 83.8m as of 2026-05-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $12.87. Options: 16 managers hold calls ($24.1m notional), 6 hold puts ($7.6m).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 85 |
| Q4 2022 | 75 |
| Q1 2023 | 67 |
| Q2 2023 | 84 |
| Q3 2023 | 99 |
| Q4 2023 | 139 |
| Q1 2024 | 164 |
| Q2 2024 | 153 |
| Q3 2024 | 139 |
| Q4 2024 | 147 |
| Q1 2025 | 153 |
| Q2 2025 | 144 |
| Q3 2025 | 151 |
| Q4 2025 | 166 |
| Q1 2026 | 189 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 87 | 82 |
| Q3 2024 | 66 | 83 |
| Q4 2024 | 86 | 46 |
| Q1 2025 | 79 | 62 |
| Q2 2025 | 70 | 67 |
| Q3 2025 | 68 | 67 |
| Q4 2025 | 98 | 52 |
| Q1 2026 | 114 | 62 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $2.9m | $11.4m | 3.99 |
| Q3 2025 | $7.5m | $6.3m | 0.83 |
| Q4 2025 | $14.2m | $4.0m | 0.28 |
| Q1 2026 | $24.1m | $7.6m | 0.32 |
Biggest buyers
| Commodore Capital LP | New | +2.8m |
| CITADEL ADVISORS LLC | New | +1.9m |
| STEMPOINT CAPITAL LP | Added | +1.3m |
| EVENTIDE ASSET MANAGEMENT, LLC | New | +1.2m |
| MORGAN STANLEY | Added | +872.4k |
| Balyasny Asset Management L.P. | Added | +843.3k |
| HSBC HOLDINGS PLC | New | +833.5k |
| Sio Capital Management, LLC | New | +721.8k |
| JANUS HENDERSON GROUP PLC | Added | +663.4k |
| Blue Owl Capital Holdings LP | Added | +520.0k |
Biggest sellers
| TCG Crossover Management, LLC | Sold out | -3.6m |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -1.4m |
| ORBIMED ADVISORS LLC | Reduced | -1.4m |
| Spruce Street Capital LP | Sold out | -981.5k |
| GOLDMAN SACHS GROUP INC | Reduced | -550.1k |
| Paradigm Biocapital Advisors LP | Reduced | -549.0k |
| Schonfeld Strategic Advisors LLC | Reduced | -454.3k |
| FEDERATED HERMES, INC. | Reduced | -347.8k |
| Alyeska Investment Group, L.P. | Reduced | -275.0k |
| Invesco Ltd. | Reduced | -207.1k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $7.3m570.2k shares |
| Ikarian Capital, LLC | New | $4.8m370.4k shares |
| GROUP ONE TRADING LLC | Added | $1.7m133.5k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | New | $1.4m108.3k shares |
| DIADEMA PARTNERS LP | New | $1.4m106.3k shares |
| SILVERBACK ASSET MANAGEMENT LLC | New | $1.3m100.0k shares |
| CITADEL ADVISORS LLC | Added | $1.3m99.4k shares |
| Centiva Capital, LP | Reduced | $1.0m77.8k shares |
| Caption Management, LLC | New | $934.5k72.5k shares |
| GOLDMAN SACHS GROUP INC | New | $903.6k70.1k shares |
Biggest puts
| Ikarian Capital, LLC | New | $4.8m370.4k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | New | $1.4m108.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.1m84.4k shares |
| Point72 Asset Management, L.P. | New | $171.4k13.3k shares |
| GROUP ONE TRADING LLC | Added | $153.4k11.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $20.6k1.6k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Janus Henderson Group Ltd. 13G · institution new · filed 2026-09-08 | 10.9% |
| TANG CAPITAL MANAGEMENT LLC 13G · passive investor new · filed 2026-10-27 | 9.6% |
| Cormorant Asset Management, LP 13G · institution -1.6 pts · filed 2026-08-14 | 8.3% |
| FEDERATED HERMES, INC. 13G · institution +1.4 pts · filed 2026-10-07 | 8.0% |
| BlackRock, Inc. 13G · institution +1.2 pts · filed 2026-07-28 | 7.7% |
| FRANKLIN RESOURCES INC 13G · institution -1.4 pts · filed 2025-01-27 | 6.1% |
| Adage Capital Management, L.P. 13G · institution +1.8 pts · filed 2026-08-12 | 5.7% |
| Commodore Capital LP 13G · passive investor new · filed 2026-06-03 | 5.1% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.0% |
Fell to 5% or below in the last year: Paradigm Biocapital Advisors LP (3.8%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26; now reported by VANGUARD CAPITAL MANAGEMENT LLC), TCG Crossover GP II, LLC (4.3%, 2026-02-17)
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 0 | — | 1 | $266.8k | $266.8k |
| Q3 2024 | 4 | $184.5k | 1 | $116.9k | $116.9k |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 1 | $113.5k | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 2 | $182.6k | $182.6k |
| Q1 2026 | 1 | $19.7k | 1 | $807.6k | $807.6k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-03-16 | Duker Jay S. President and CEO, director · By Family Trust | Bought | $19.7k1.5k shares |
| 2026-03-04 | Ribeiro Ramiro Chief Medical Officer | Sold plan | $43.6k2.4k shares |
| 2026-02-17 | Ribeiro Ramiro Chief Medical Officer | Sold plan | $36.6k2.4k shares |
| 2026-01-05 | Ribeiro Ramiro Chief Medical Officer | Sold plan | $727.5k42.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| MONTANOVA CAPITAL, LLC 2.90% of their portfolio | 8.3m $106.9m | Added +468.7k |
| Cormorant Asset Management, LP 5.37% of their portfolio | 8.3m $106.5m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 7.2m $92.5m | Added +389.5k |
| FEDERATED HERMES, INC. 0.12% of their portfolio | 5.7m $73.1m | Reduced -347.8k |
| FRANKLIN RESOURCES INC 0.02% of their portfolio | 5.0m $65.1m | Added +71.7k |
| JANUS HENDERSON GROUP PLC 0.02% of their portfolio | 3.6m $46.4m | Added +663.4k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 3.6m $45.9m | First filing |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.07% of their portfolio | 3.3m $42.5m | Reduced -1.4m |
| Paradigm Biocapital Advisors LP 0.83% of their portfolio | 3.1m $40.5m | Reduced -549.0k |
| Commodore Capital LP 2.11% of their portfolio | 2.8m $36.4m | New |
| STATE STREET CORP 0.00% of their portfolio | 2.1m $27.0m | Added +262.4k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.0m $25.6m | Added +84.3k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 1.9m $24.6m | New |
| Aberdeen Group plc 0.04% of their portfolio | 1.7m $22.4m | Added +132.4k |
| STEMPOINT CAPITAL LP 2.02% of their portfolio | 1.6m $20.9m | Added +1.3m |
| Balyasny Asset Management L.P. 0.04% of their portfolio | 1.4m $18.5m | Added +843.3k |
| Parkman Healthcare Partners LLC 1.81% of their portfolio | 1.4m $17.5m | Added +266.8k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.27% of their portfolio | 1.2m $16.1m | New |
| MORGAN STANLEY 0.00% of their portfolio | 1.1m $14.1m | Added +872.4k |
| Essex Woodlands Management, Inc. 5.58% of their portfolio | 1.1m $14.0m | Unchanged |
| ORBIMED ADVISORS LLC 0.30% of their portfolio | 1.1m $13.8m | Reduced -1.4m |
| 5AM Venture Management, LLC 3.76% of their portfolio | 1.1m $13.5m | Unchanged |
| Rosalind Advisors, Inc. 5.48% of their portfolio | 1.0m $13.4m | Added +346.7k |
| Blue Owl Capital Holdings LP 3.23% of their portfolio | 912.6k $11.8m | Added +520.0k |
| HSBC HOLDINGS PLC 0.01% of their portfolio | 833.5k $10.7m | New |
| Patient Square Capital LP 1.82% of their portfolio | 795.0k $10.2m | Added +15.0k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 793.9k $10.2m | First filing |
| Artia Global Partners LP 2.23% of their portfolio | 767.1k $9.9m | Unchanged |
| Sio Capital Management, LLC 1.34% of their portfolio | 721.8k $9.3m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 699.7k $9.0m | Reduced -550.1k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 676.8k $8.7m | Added +99.2k |
| Candriam S.C.A. 0.05% of their portfolio | 674.4k $8.7m | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 640.1k $8.3m | Reduced -8.4k |
| Principia Wealth Advisory, LLC 4.62% of their portfolio | 633.8k $8.2m | Added +103.0k |
| Alyeska Investment Group, L.P. 0.02% of their portfolio | 509.4k $6.6m | Reduced -275.0k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 504.5k $6.5m | First filing |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 475.2k $6.1m | Reduced -81.3k |
| ExodusPoint Capital Management, LP 0.06% of their portfolio | 458.1k $5.9m | Reduced -86.0k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 430.3k $5.5m | Added +291.9k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 423.3k $5.5m | Added +210.0k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 401.1k $5.2m | Reduced -942 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 383.4k $4.9m | Reduced -32.7k |
| MYDA Advisors LLC 1.00% of their portfolio | 330.0k $4.3m | Added +30.0k |
| Simplify Asset Management Inc. 0.06% of their portfolio | 326.1k $4.2m | Reduced -49.1k |
| Bleichroeder LP 0.71% of their portfolio | 316.5k $4.1m | Unchanged |
| Walleye Capital LLC 0.02% of their portfolio | 300.2k $3.9m | New |
| Granahan Investment Management, LLC 0.19% of their portfolio | 297.1k $3.8m | Reduced -69.6k |
| Nuveen, LLC 0.00% of their portfolio | 260.3k $3.4m | Added +79.0k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 258.9k $3.3m | Added +70.7k |
| Rock Springs Capital Management LP 0.20% of their portfolio | 258.7k $3.3m | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 255.4k $3.3m | Reduced -1.4k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% of their portfolio | 245.4k $3.2m | Reduced -920 |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 239.1k $3.1m | Added +12.3k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 218.6k $2.6m | Added +50.2k |
| Propel Bio Management, LLC 1.76% of their portfolio | 215.8k $2.8m | New |
| Schonfeld Strategic Advisors LLC 0.02% of their portfolio | 207.1k $2.7m | Reduced -454.3k |
| Jump Financial, LLC 0.04% of their portfolio | 198.4k $2.6m | New |
| HighVista Strategies LLC 0.65% of their portfolio | 183.0k $2.4m | New |
| DIADEMA PARTNERS LP 0.95% of their portfolio | 178.5k $2.3m | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 161.8k $2.1m | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 149.9k $1.9m | Added +148.7k |
| Swiss National Bank 0.00% of their portfolio | 147.4k $1.9m | New |
| Susquehanna Portfolio Strategies, LLC 0.03% of their portfolio | 139.4k $1.8m | Added +64.4k |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 132.2k $1.7m | Unchanged |
| Invesco Ltd. 0.00% of their portfolio | 131.9k $1.7m | Reduced -207.1k |
| UBS Group AG 0.00% of their portfolio | 129.5k $1.7m | Reduced -59.2k |
| FMR LLC 0.00% of their portfolio | 129.4k $1.7m | Added +110.3k |
| Corient Private Wealth LP 0.00% of their portfolio | 127.5k $9.5k | Reduced -127.5k |
| ESSEX INVESTMENT MANAGEMENT CO LLC 0.26% of their portfolio | 127.2k $1.6m | Added +2.3k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 126.7k $1.6m | Added +66.4k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 117.3k $1.5m | Added +55.7k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 116.5k $1.5m | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 106.1k $1.4m | Added +13.6k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 105.1k $1.4m | Added +100.4k |
| Woodline Partners LP 0.00% of their portfolio | 100.5k $1.3m | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 96.7k $1.2m | Added +7.6k |
| E Fund Management Co., Ltd. 0.04% of their portfolio | 94.5k $1.2m | First filing |
| Squarepoint Ops LLC 0.00% of their portfolio | 80.1k $1.0m | New |
| Waverly Advisors, LLC 0.01% of their portfolio | 77.9k $1.0m | Reduced -149 |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 75.3k $1.4m | Added +246 |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 71.6k $923.3k | Added +65.7k |
| WOODSTOCK CORP 0.08% of their portfolio | 68.5k $882.5k | Unchanged |
| XTX Topco Ltd 0.01% of their portfolio | 66.6k $859.1k | New |
| Persistent Asset Partners Ltd 0.30% of their portfolio | 59.0k $760.4k | Added +53.6k |
| Marex Group Ltd 0.01% of their portfolio | 56.3k $725.9k | Added +8.5k |
| TWINBEECH CAPITAL LP 0.08% of their portfolio | 56.3k $725.7k | New |
| Legal & General Group Plc 0.00% of their portfolio | 53.1k $684.7k | Added +46.4k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 50.5k $651.0k | Added +21.7k |
| SILVERBACK ASSET MANAGEMENT LLC 0.13% of their portfolio | 50.0k $644.5k | New |
| Erste Asset Management GmbH 0.01% of their portfolio | 50.0k $592.5k | Unchanged |
| VANGUARD ASSET MANAGEMENT, Ltd 0.00% of their portfolio | 49.1k $633.3k | First filing |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 47.8k $615.8k | Reduced -170 |
| SBI Okasan Asset Management Co.Ltd. 0.02% of their portfolio | 45.7k $541.5k | Added +12.1k |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 44.5k $573.2k | Added +1.8k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 43.5k $560.3k | Added +1.7k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 42.5k $548.1k | Reduced -563 |
| SCOTIA CAPITAL INC. 0.00% of their portfolio | 41.8k $538.2k | Added +10.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 40.1k $475.3k | Added +2.9k |
| Legato Capital Management LLC 0.05% of their portfolio | 39.9k $514.0k | Reduced -556 |
| China Universal Asset Management Co., Ltd. 0.04% of their portfolio | 39.7k $511.6k | Added +10.2k |