EYEPOINT PHARMACEUTICALS INC EYPT
COM NEW · Common Stock · CUSIP 30233G209
Company specialising in the application of microelectromechanical systems (MEMS) and nanotechnology to drug delivery
- SectorTechnology
- IndustryLaboratory Analytical Instruments
- HeadquartersWatertown, MA
- Websitepsivida.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.8m this quarter). Holder counts are more reliable. Shares outstanding: 86.2m as of 2026-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $14.30. Options: 15 managers hold calls ($24.6m notional), 10 hold puts ($42.6m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 85 |
| Q4 2022 | 75 |
| Q1 2023 | 67 |
| Q2 2023 | 84 |
| Q3 2023 | 99 |
| Q4 2023 | 139 |
| Q1 2024 | 164 |
| Q2 2024 | 153 |
| Q3 2024 | 139 |
| Q4 2024 | 147 |
| Q1 2025 | 153 |
| Q2 2025 | 144 |
| Q3 2025 | 151 |
| Q4 2025 | 166 |
| Q1 2026 | 189 |
| Q2 2026 | 189 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 66 | 83 |
| Q4 2024 | 86 | 46 |
| Q1 2025 | 79 | 62 |
| Q2 2025 | 70 | 67 |
| Q3 2025 | 68 | 67 |
| Q4 2025 | 98 | 52 |
| Q1 2026 | 114 | 62 |
| Q2 2026 | 88 | 83 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $7.5m | $6.3m | 0.83 |
| Q4 2025 | $14.2m | $4.0m | 0.28 |
| Q1 2026 | $24.1m | $7.6m | 0.32 |
| Q2 2026 | $24.6m | $42.6m | 1.73 |
Biggest buyers
| Commodore Capital LP | Added | +1.8m |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Added | +1.5m |
| TWO SIGMA INVESTMENTS, LP | Added | +750.8k |
| DIMENSIONAL FUND ADVISORS LP | Added | +440.6k |
| AMERIPRISE FINANCIAL INC | Added | +425.1k |
| Balyasny Asset Management L.P. | Added | +373.6k |
| Ghisallo Capital Management LLC | New | +350.0k |
| Eversept Partners, LP | New | +297.7k |
| BlackRock, Inc. | Added | +285.9k |
| Aberdeen Group plc | Added | +270.4k |
Biggest sellers
| STEMPOINT CAPITAL LP | Reduced | -1.3m |
| Cormorant Asset Management, LP | Reduced | -1.3m |
| MORGAN STANLEY | Reduced | -759.4k |
| ExodusPoint Capital Management, LP | Sold out | -458.1k |
| BANK OF AMERICA CORP /DE/ | Reduced | -318.4k |
| Paradigm Biocapital Advisors LP | Reduced | -252.0k |
| FRANKLIN RESOURCES INC | Reduced | -241.5k |
| GOLDMAN SACHS GROUP INC | Reduced | -234.6k |
| DIADEMA PARTNERS LP | Sold out | -178.5k |
| Blue Owl Capital Holdings LP | Reduced | -150.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $7.9m552.4k shares |
| Ikarian Capital, LLC | Unchanged | $5.3m370.4k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Unchanged | $1.5m108.3k shares |
| DIADEMA PARTNERS LP | Unchanged | $1.5m106.3k shares |
| GROUP ONE TRADING LLC | Reduced | $1.5m104.3k shares |
| SILVERBACK ASSET MANAGEMENT LLC | Unchanged | $1.4m100.0k shares |
| CITADEL ADVISORS LLC | Reduced | $1.4m94.9k shares |
| Caption Management, LLC | Unchanged | $1.0m72.5k shares |
| GOLDMAN SACHS GROUP INC | Unchanged | $1.0m70.1k shares |
| JANE STREET GROUP, LLC | Reduced | $715.0k50.0k shares |
Biggest puts
| PERCEPTIVE ADVISORS LLC | New | $28.6m2.0m shares |
| Ikarian Capital, LLC | Unchanged | $5.3m370.4k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $3.0m212.5k shares |
| CITADEL ADVISORS LLC | New | $2.6m179.0k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Unchanged | $1.5m108.3k shares |
| SIMPLEX TRADING, LLC | Added | $780.8k54.6k shares |
| Caption Management, LLC | New | $326.0k22.8k shares |
| Point72 Asset Management, L.P. | Added | $214.5k15.0k shares |
| JANE STREET GROUP, LLC | New | $193.1k13.5k shares |
| GROUP ONE TRADING LLC | Reduced | $21.4k1.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Janus Henderson Group Ltd. 13G · institution new · filed 2026-09-08 | 10.9% |
| TANG CAPITAL MANAGEMENT LLC 13G · passive investor new · filed 2026-10-27 | 9.6% |
| Cormorant Asset Management, LP 13G · institution -1.6 pts · filed 2026-08-14 | 8.3% |
| FEDERATED HERMES, INC. 13G · institution +1.4 pts · filed 2026-10-07 | 8.0% |
| BlackRock, Inc. 13G · institution +1.2 pts · filed 2026-07-28 | 7.7% |
| FRANKLIN RESOURCES INC 13G · institution -1.4 pts · filed 2025-01-27 | 6.1% |
| Adage Capital Management, L.P. 13G · institution +1.8 pts · filed 2026-08-12 | 5.7% |
| Commodore Capital LP 13G · passive investor new · filed 2026-06-03 | 5.1% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.0% |
Fell to 5% or below in the last year: Paradigm Biocapital Advisors LP (3.8%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26; now reported by VANGUARD CAPITAL MANAGEMENT LLC), TCG Crossover GP II, LLC (4.3%, 2026-02-17)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 1 | $113.5k | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 2 | $182.6k | $182.6k |
| Q1 2026 | 1 | $19.7k | 1 | $807.6k | $807.6k |
| Q2 2026 | 0 | — | 1 | $109.7k | $109.7k |
| Q3 2026 | 1 | $52.3k | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-08-18 | Zaderej Karen L. Director | Bought | $52.3k10.6k shares |
| 2026-06-30 | Ribeiro Ramiro Chief Medical Officer | Sold plan | $73.2k4.9k shares |
| 2026-04-17 | Ribeiro Ramiro Chief Medical Officer | Sold plan | $36.6k2.4k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| MONTANOVA CAPITAL, LLC 2.49% of their portfolio | 8.3m $118.6m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 7.5m $106.7m | Added +285.9k |
| Cormorant Asset Management, LP 5.13% of their portfolio | 7.0m $100.1m | Reduced -1.3m |
| FEDERATED HERMES, INC. 0.12% of their portfolio | 5.7m $81.2m | Added +11.5k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.10% of their portfolio | 4.8m $69.0m | Added +1.5m |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 4.8m $68.7m | Reduced -241.5k |
| Commodore Capital LP 3.92% of their portfolio | 4.6m $65.8m | Added +1.8m |
| Jupiter Topco LLC 0.02% of their portfolio | 3.8m $53.9m | First filing |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 3.6m $51.9m | Added +70.7k |
| Paradigm Biocapital Advisors LP 0.77% of their portfolio | 2.9m $41.3m | Reduced -252.0k |
| STATE STREET CORP 0.00% of their portfolio | 2.4m $33.7m | Added +260.3k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 2.1m $29.5m | Added +78.7k |
| Aberdeen Group plc 0.04% of their portfolio | 2.0m $28.7m | Added +270.4k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 2.0m $28.3m | Added +71.7k |
| Balyasny Asset Management L.P. 0.05% of their portfolio | 1.8m $25.9m | Added +373.6k |
| Parkman Healthcare Partners LLC 1.89% of their portfolio | 1.3m $18.4m | Reduced -66.6k |
| EVENTIDE ASSET MANAGEMENT, LLC 0.24% of their portfolio | 1.2m $17.8m | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 1.2m $16.9m | Added +750.8k |
| Essex Woodlands Management, Inc. 6.10% of their portfolio | 1.1m $15.5m | Unchanged |
| ORBIMED ADVISORS LLC 0.29% of their portfolio | 1.1m $15.3m | Unchanged |
| 5AM Venture Management, LLC 5.22% of their portfolio | 1.1m $15.0m | Unchanged |
| Rosalind Advisors, Inc. 5.31% of their portfolio | 988.2k $14.1m | Reduced -48.5k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 971.0k $13.9m | Added +177.1k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 848.4k $12.1m | Added +425.1k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 841.7k $12.0m | Added +440.6k |
| HSBC HOLDINGS PLC 0.01% of their portfolio | 833.5k $11.9m | Unchanged |
| Candriam S.C.A. 0.05% of their portfolio | 787.8k $11.3m | Added +113.4k |
| Artia Global Partners LP 2.09% of their portfolio | 767.1k $11.0m | Unchanged |
| Blue Owl Capital Holdings LP 1.66% of their portfolio | 762.6k $10.9m | Reduced -150.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 720.9k $10.3m | Added +44.1k |
| Patient Square Capital LP 1.59% of their portfolio | 720.0k $10.3m | Reduced -75.0k |
| Principia Wealth Advisory, LLC 4.65% of their portfolio | 649.9k $9.3m | Added +16.2k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 647.6k $9.3m | Added +7.5k |
| Sio Capital Management, LLC 1.53% of their portfolio | 623.1k $8.9m | Reduced -98.7k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 559.2k $8.0m | Added +54.7k |
| Alyeska Investment Group, L.P. 0.02% of their portfolio | 509.4k $7.3m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 500.1k $7.2m | Added +24.9k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 465.1k $6.7m | Reduced -234.6k |
| Simplify Asset Management Inc. 0.08% of their portfolio | 400.0k $5.7m | Added +73.9k |
| Ghisallo Capital Management LLC 0.10% of their portfolio | 350.0k $5.0m | New |
| STEMPOINT CAPITAL LP 0.84% of their portfolio | 338.5k $4.8m | Reduced -1.3m |
| MORGAN STANLEY 0.00% of their portfolio | 336.7k $4.8m | Reduced -759.4k |
| E Fund Management Co., Ltd. 0.11% of their portfolio | 330.8k $4.7m | Added +236.3k |
| Jump Financial, LLC 0.04% of their portfolio | 320.8k $4.6m | Added +122.4k |
| Bleichroeder LP 0.81% of their portfolio | 316.5k $4.5m | Unchanged |
| Woodline Partners LP 0.01% of their portfolio | 300.5k $4.3m | Added +200.0k |
| Eversept Partners, LP 0.23% of their portfolio | 297.7k $4.3m | New |
| Rock Springs Capital Management LP 0.19% of their portfolio | 268.5k $3.8m | Added +9.8k |
| CITIGROUP INC 0.00% of their portfolio | 266.9k $3.8m | Added +238.0k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 250.8k $3.6m | Reduced -4.6k |
| MYDA Advisors LLC 0.87% of their portfolio | 250.0k $3.6m | Reduced -80.0k |
| UBS Group AG 0.00% of their portfolio | 241.4k $3.5m | Added +111.9k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% of their portfolio | 234.8k $3.4m | Reduced -10.6k |
| Schonfeld Strategic Advisors LLC 0.02% of their portfolio | 229.8k $3.3m | Added +22.7k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 228.6k $3.3m | Reduced -30.4k |
| Nuveen, LLC 0.00% of their portfolio | 193.5k $2.8m | Reduced -66.8k |
| Propel Bio Management, LLC 1.43% of their portfolio | 191.7k $2.7m | Reduced -24.1k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 189.1k $2.7m | Added +72.6k |
| Walleye Capital LLC 0.01% of their portfolio | 188.2k $2.7m | Reduced -112.0k |
| Susquehanna Portfolio Strategies, LLC 0.04% of their portfolio | 187.8k $2.7m | Added +48.4k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 169.3k $2.4m | Reduced -49.2k |
| HighVista Strategies LLC 0.51% of their portfolio | 155.7k $2.2m | Reduced -27.3k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 152.8k $2.2m | Reduced -86.3k |
| Granahan Investment Management, LLC 0.08% of their portfolio | 149.4k $2.1m | Reduced -147.7k |
| Swiss National Bank 0.00% of their portfolio | 142.3k $2.0m | Reduced -5.1k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 139.8k $2.0m | Added +13.1k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 135.3k $1.9m | Reduced -14.5k |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 132.2k $1.9m | Unchanged |
| Corient Private Wealth LP 0.00% of their portfolio | 127.2k $1.8m | Reduced -303 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 125.0k $1.8m | Added +18.9k |
| ESSEX INVESTMENT MANAGEMENT CO LLC 0.23% of their portfolio | 121.7k $1.7m | Reduced -5.5k |
| Invesco Ltd. 0.00% of their portfolio | 116.2k $1.7m | Reduced -15.7k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 110.1k $1.6m | Added +38.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 102.6k $1.5m | Reduced -2.5k |
| Squarepoint Ops LLC 0.00% of their portfolio | 98.0k $1.4m | Added +17.9k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 97.4k $1.4m | Added +760 |
| SG Americas Securities, LLC 0.00% of their portfolio | 88.8k $1.3m | New |
| ALGERT GLOBAL LLC 0.01% of their portfolio | 79.0k $1.1m | New |
| Waverly Advisors, LLC 0.01% of their portfolio | 77.9k $1.1m | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 75.3k $971.1k | Unchanged |
| Cinctive Capital Management LP 0.04% of their portfolio | 72.6k $1.0m | Added +44.7k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 70.7k $1.0m | Added +41.4k |
| WOODSTOCK CORP 0.08% of their portfolio | 68.5k $979.0k | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 65.0k $930.2k | Reduced -318.4k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 62.9k $900.0k | Added +26.0k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 60.5k $865.7k | Added +38.9k |
| Legal & General Group Plc 0.00% of their portfolio | 59.2k $846.8k | Added +6.1k |
| FOX RUN MANAGEMENT, L.L.C. 0.14% of their portfolio | 58.5k $837.0k | New |
| HRT FINANCIAL LP 0.00% of their portfolio | 57.2k $818.0k | New |
| Y-Intercept (Hong Kong) Ltd 0.01% of their portfolio | 51.2k $732.0k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 50.1k $716.3k | Added +2.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 50.1k $706.2k | Added +9.9k |
| SILVERBACK ASSET MANAGEMENT LLC 0.09% of their portfolio | 50.0k $715.0k | Unchanged |
| Erste Asset Management GmbH 0.01% of their portfolio | 50.0k $705.5k | Unchanged |
| VANGUARD ASSET MANAGEMENT, Ltd 0.00% of their portfolio | 49.1k $702.5k | Unchanged |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 48.6k $694.6k | New |
| SBI Okasan Asset Management Co.Ltd. 0.02% of their portfolio | 45.7k $644.8k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 43.9k $628.5k | Added +17.8k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 43.5k $621.6k | Unchanged |
| SCOTIA CAPITAL INC. 0.00% of their portfolio | 41.8k $597.0k | Unchanged |