Vault-13

EXACT SCIENCES CORP EXAS

COM · Common Stock · CUSIP 30063P105 · ISIN US30063P1057

560 institutional holders +0 vs Q1 2025
178,106,549178.1m shares reported held*
$9.5bnreported value*
91 new 179 added 185 reduced 93 sold out net sold ≈ $193.7m (-3.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($30.7m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $53.15. Options: 20 managers hold calls ($84.9m notional), 25 hold puts ($130.3m).

Trends to Q2 2025

Institutional holders

Managers reporting a position, each quarter

0250500750Q3 22: 479Q4 22: 551Q1 23: 584Q2 23: 655Q3 23: 626Q4 23: 648Q1 24: 625Q2 24: 545Q3 24: 602Q4 24: 596Q1 25: 560Q2 25: 560560Q3 22Q2 23Q1 24Q4 24Q2 25
Numbers
QuarterHolders
Q3 2022479
Q4 2022551
Q1 2023584
Q2 2023655
Q3 2023626
Q4 2023648
Q1 2024625
Q2 2024545
Q3 2024602
Q4 2024596
Q1 2025560
Q2 2025560

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
4000400Q3 23: 292 bought or addedQ3 23: 292 cut or sold outQ4 23: 285 bought or addedQ4 23: 287 cut or sold outQ4 23Q1 24: 298 bought or addedQ1 24: 292 cut or sold outQ2 24: 266 bought or addedQ2 24: 315 cut or sold outQ2 24Q3 24: 283 bought or addedQ3 24: 256 cut or sold outQ4 24: 238 bought or addedQ4 24: 294 cut or sold outQ4 24Q1 25: 233 bought or addedQ1 25: 293 cut or sold outQ2 25: 270 bought or addedQ2 25: 278 cut or sold outQ2 25
Numbers
QuarterBought or addedCut or sold out
Q3 2023292292
Q4 2023285287
Q1 2024298292
Q2 2024266315
Q3 2024283256
Q4 2024238294
Q1 2025233293
Q2 2025270278

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$100m$200m$300mQ3 24 calls: $194.3mQ3 24 puts: $169.7mQ3 24P/C 0.87Q4 24 calls: $251.0mQ4 24 puts: $112.5mQ4 24P/C 0.45Q1 25 calls: $83.1mQ1 25 puts: $71.4mQ1 25P/C 0.86Q2 25 calls: $84.9mQ2 25 puts: $130.3mQ2 25P/C 1.54
Numbers
QuarterCallsPutsP/C
Q3 2024$194.3m$169.7m0.87
Q4 2024$251.0m$112.5m0.45
Q1 2025$83.1m$71.4m0.86
Q2 2025$84.9m$130.3m1.54

Biggest buyers

MASSACHUSETTS FINANCIAL SERVICES CO /MA/ New +2,969,613+3.0m
GOLDMAN SACHS GROUP INC Added +1,486,137+1.5m
Holocene Advisors, LP Added +1,404,086+1.4m
READYSTATE ASSET MANAGEMENT LP Added +893,827+893.8k
AQR CAPITAL MANAGEMENT LLC Added +741,517+741.5k
MILLENNIUM MANAGEMENT LLC Added +727,457+727.5k
Vestal Point Capital, LP New +700,000+700.0k
Woodline Partners LP Added +696,225+696.2k
Stephens Investment Management Group LLC New +530,083+530.1k
RENAISSANCE TECHNOLOGIES LLC Added +494,904+494.9k

Biggest sellers

PRICE T ROWE ASSOCIATES INC /MD/ Reduced -2,700,607-2.7m
T. Rowe Price Investment Management, Inc. Reduced -2,596,623-2.6m
BlackRock, Inc. Reduced -1,388,121-1.4m
STATE STREET CORP Reduced -1,234,872-1.2m
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC Reduced -1,219,545-1.2m
AMERIPRISE FINANCIAL INC Reduced -1,140,737-1.1m
CITIGROUP INC Reduced -1,048,743-1.0m
ARMISTICE CAPITAL, LLC Reduced -1,030,413-1.0m
FMR LLC Reduced -831,230-831.2k
UBS Group AG Reduced -789,231-789.2k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $27.7m520.4k shares
CITADEL ADVISORS LLC Reduced $14.1m264.8k shares
GROUP ONE TRADING LLC Added $6.9m129.7k shares
Walleye Trading LLC Added $6.5m121.4k shares
JANE STREET GROUP, LLC Reduced $4.9m91.4k shares
BANQUE PICTET & CIE SA New $4.6m86.7k shares
Caption Management, LLC New $4.1m76.5k shares
SIMPLEX TRADING, LLC Reduced $3.5m66.1k shares
IMC-Chicago, LLC Added $2.9m53.9k shares
Balyasny Asset Management L.P. New $2.6m48.4k shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $24.9m468.7k shares
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC New $15.9m300.0k shares
Walleye Trading LLC Reduced $13.5m254.9k shares
Balyasny Asset Management L.P. New $12.6m238.0k shares
JANE STREET GROUP, LLC Added $9.5m179.6k shares
BANK OF AMERICA CORP /DE/ Reduced $7.7m144.2k shares
CITADEL ADVISORS LLC Reduced $5.5m103.1k shares
Walleye Capital LLC Added $4.3m81.3k shares
MILLENNIUM MANAGEMENT LLC Added $3.2m60.0k shares
LMR Partners LLP Added $3.2m60.0k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

No one currently above 5% in the filings since 19 Dec 2024.

Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26), Capital World Investors (0.5%, 2026-02-13), FMR LLC (2.9%, 2025-12-05)

Holders, Q2 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FMR LLC 0.08% of their portfolio BOSTON, MA 26,892,31626.9m $1.4bn $1.4bn 0.08% Reduced -831.2k -831,230
2 Capital World Investors 0.14% of their portfolio LOS ANGELES, CA 18,200,02218.2m $967.2m $967.2m 0.14% Added +364.7k +364,745
3 VANGUARD GROUP INC 0.02% of their portfolio Valley Forge, PA 17,907,45917.9m $951.6m $951.6m 0.02% Added +269.8k +269,785
4 WELLINGTON MANAGEMENT GROUP LLP 0.12% of their portfolio Boston, MA 12,003,79012.0m $637.9m $637.9m 0.12% Reduced -497.5k -497,526
5 BlackRock, Inc. 0.01% of their portfolio New York, NY 10,532,60010.5m $559.7m $559.7m 0.01% Reduced -1.4m -1,388,121
6 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 5,379,0275.4m $285.8m $285.8m 0.01% Reduced -1.2m -1,234,872
7 PRICE T ROWE ASSOCIATES INC /MD/ 0.02% of their portfolio BALTIMORE, MD 3,703,2653.7m $196.8m $196.8m 0.02% Reduced -2.7m -2,700,607
8 GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio BOSTON, MA 3,237,0403.2m $172.0m $172.0m 0.01% Reduced -29.4k -29,399
9 MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.05% of their portfolio Boston, MA 2,969,6133.0m $157.8m $157.8m 0.05% New
10 MACKENZIE FINANCIAL CORP 0.20% of their portfolio TORONTO ONTARIO, A6 2,855,8012.9m $151.8m $151.8m 0.20% Reduced -425.8k -425,838
11 Champlain Investment Partners, LLC 0.94% of their portfolio BURLINGTON, VT 2,529,8202.5m $134.4m $134.4m 0.94% Added +282.8k +282,825
12 AMERIPRISE FINANCIAL INC 0.03% of their portfolio MINNEAPOLIS, MN 2,223,0462.2m $118.1m $118.1m 0.03% Reduced -1.1m -1,140,737
13 GOLDMAN SACHS GROUP INC 0.02% of their portfolio NEW YORK, NY 2,214,1982.2m $117.7m $117.7m 0.02% Added +1.5m +1,486,137
14 MILLENNIUM MANAGEMENT LLC 0.10% of their portfolio NEW YORK, NY 2,201,6432.2m $117.0m $117.0m 0.10% Added +727.5k +727,457
15 Holocene Advisors, LP 0.28% of their portfolio New York, NY 2,145,1812.1m $114.0m $114.0m 0.28% Added +1.4m +1,404,086
16 WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.28% of their portfolio CHICAGO, IL 2,020,1702.0m $107.4m $107.4m 0.28% Reduced -228.9k -228,868
17 DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio AUSTIN, TX 1,949,5511.9m $103.6m $103.6m 0.02% Added +348.3k +348,345
18 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.02% of their portfolio NEW YORK, NY 1,909,4131.9m $101.5m $101.5m 0.02% Reduced -1.2m -1,219,545
19 BAMCO INC /NY/ 0.27% of their portfolio NEW YORK, NY 1,861,3411.9m $98.9m $98.9m 0.27% Added +388.6k +388,627
20 AQR CAPITAL MANAGEMENT LLC 0.08% of their portfolio Greenwich, CT 1,753,2831.8m $93.2m $93.2m 0.08% Added +741.5k +741,517
21 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio SAN FRANCISCO, CA 1,434,8551.4m $76.2m $76.2m 0.01% Added +43.3k +43,256
22 Ensign Peak Advisors, Inc 0.13% of their portfolio SALT LAKE CITY, UT 1,387,7971.4m $73.7m $73.7m 0.13% Added +168.3k +168,345
23 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 1,383,7611.4m $73.5m $73.5m 0.00% Reduced -391.6k -391,564
24 Spyglass Capital Management LLC 4.26% of their portfolio Greenbrae, CA 1,358,6631.4m $72.2m $72.2m 4.26% Reduced -218.0k -217,971
25 Woodline Partners LP 0.35% of their portfolio San Francisco, CA 1,234,0881.2m $65.6m $65.6m 0.35% Added +696.2k +696,225
26 GROUPAMA ASSET MANAGMENT 0.02% of their portfolio PARIS, I0 1,200,0001.2m $1.1m $1.1m 0.02% Unchanged
27 NORTHERN TRUST CORP 0.01% of their portfolio CHICAGO, IL 1,113,5991.1m $59.2m $59.2m 0.01% Reduced -23.3k -23,330
28 ZEVENBERGEN CAPITAL INVESTMENTS LLC 1.06% of their portfolio EDMONDS, WA 1,018,1831.0m $54.1m $54.1m 1.06% Reduced -149.8k -149,781
29 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 998,606998.6k $53.1m $53.1m 0.00% Added +22.0k +21,980
30 NORGES BANK 0.01% of their portfolio OSLO, Q8 910,277910.3k $48.4m $48.4m 0.01% Added +435.2k +435,158
31 READYSTATE ASSET MANAGEMENT LP 1.99% of their portfolio CHICAGO, IL 900,231900.2k $47.8m $47.8m 1.99% Added +893.8k +893,827
32 Connor, Clark & Lunn Investment Management Ltd. 0.17% of their portfolio VANCOUVER, A1 884,637884.6k $47.0m $47.0m 0.17% Added +115.4k +115,387
33 C WorldWide Group Holding A/S 0.60% of their portfolio COPENHAGEN, G7 834,272834.3k $44.3m $44.3m 0.60% Reduced -2.3k -2,346
34 PEREGRINE CAPITAL MANAGEMENT LLC 1.32% of their portfolio MINNEAPOLIS, MN 822,617822.6k $43.7m $43.7m 1.32% Added +117.3k +117,331
35 Nuveen, LLC 0.01% of their portfolio CHARLOTTE, NC 817,149817.1k $43.4m $43.4m 0.01% Reduced -230.1k -230,067
36 SCHRODER INVESTMENT MANAGEMENT GROUP 0.04% of their portfolio London, X0 811,200811.2k $43.1m $43.1m 0.04% Added +53.8k +53,792
37 BAILLIE GIFFORD & CO 0.03% of their portfolio EDINBURGH, X0 780,016780.0k $41.5m $41.5m 0.03% Reduced -52.6k -52,552
38 ARMISTICE CAPITAL, LLC 1.49% of their portfolio NEW YORK, NY 741,956742.0k $39.4m $39.4m 1.49% Reduced -1.0m -1,030,413
39 PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio DES MOINES, IA 738,804738.8k $39.3m $39.3m 0.02% Reduced -35.2k -35,171
40 FIRST TRUST ADVISORS LP 0.03% of their portfolio Wheaton, IL 729,930729.9k $38.8m $38.8m 0.03% Reduced -19.0k -18,983
41 Vestal Point Capital, LP 1.96% of their portfolio NEW YORK, NY 700,000700.0k $37.2m $37.2m 1.96% New
42 Amundi 0.01% of their portfolio Paris, I0 626,129626.1k $33.7m $33.7m 0.01% Reduced -147.8k -147,842
43 DEUTSCHE BANK AG\ 0.01% of their portfolio FRANKFURT AM MAIN, 2M 608,692608.7k $32.3m $32.3m 0.01% Reduced -335.3k -335,329
44 Bank of New York Mellon Corp 0.01% of their portfolio NEW YORK, NY 607,964608.0k $32.3m $32.3m 0.01% Reduced -197.7k -197,654
45 ORBIMED ADVISORS LLC 0.81% of their portfolio New York, NY 607,316607.3k $32.3m $32.3m 0.81% Reduced -72.5k -72,500
46 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 593,258593.3k $31.5m $31.5m 0.00% Added +89.3k +89,289
47 AXA S.A. 0.09% of their portfolio PARIS, I0 574,143574.1k $30.5m $30.5m 0.09% Added +17.5k +17,493
48 Rock Springs Capital Management LP 1.89% of their portfolio Baltimore, MD 572,000572.0k $30.4m $30.4m 1.89% Added +92.0k +92,000
49 EVENTIDE ASSET MANAGEMENT, LLC 0.53% of their portfolio Boston, MA 565,546565.5k $30.1m $30.1m 0.53% Unchanged
50 Artemis Investment Management LLP 0.38% of their portfolio EDINBURGH, X0 549,614549.6k $29.2m $29.2m 0.38% Added +281.0k +281,014
51 HighTower Advisors, LLC 0.04% of their portfolio CHICAGO, IL 534,149534.1k $28.4m $28.4m 0.04% Added +4.3k +4,276
52 Stephens Investment Management Group LLC 0.37% of their portfolio LITTLE ROCK, AR 530,083530.1k $28.2m $28.2m 0.37% New
53 RENAISSANCE TECHNOLOGIES LLC 0.04% of their portfolio NEW YORK, NY 528,804528.8k $28.1m $28.1m 0.04% Added +494.9k +494,904
54 JENNISON ASSOCIATES LLC 0.02% of their portfolio NEW YORK, NY 505,265505.3k $26.8m $26.8m 0.02% Reduced -193.4k -193,423
55 ArrowMark Colorado Holdings LLC 0.46% of their portfolio Denver, CO 484,328484.3k $25.7m $25.7m 0.46% Reduced -105.9k -105,873
56 Man Group plc 0.06% of their portfolio LONDON, X0 483,209483.2k $25.7m $25.7m 0.06% Added +355.2k +355,165
57 JANE STREET GROUP, LLC 0.04% of their portfolio NEW YORK, NY 468,751468.8k $24.9m $24.9m 0.04% Added +448.5k +448,451
58 UBS Group AG 0.01% of their portfolio ZURICH, V8 464,446464.4k $24.7m $24.7m 0.01% Reduced -789.2k -789,231
59 BARCLAYS PLC 0.01% of their portfolio LONDON, X0 446,641446.6k $23.7m $23.7m 0.01% Added +140.0k +139,954
60 Erste Asset Management GmbH 0.20% of their portfolio VIENNA, C4 436,323436.3k $23.2m $23.2m 0.20% Added +1.1k +1,051
61 CITADEL ADVISORS LLC 0.02% of their portfolio MIAMI, FL 435,503435.5k $23.1m $23.1m 0.02% Added +206.4k +206,449
62 MARSHALL WACE, LLP 0.03% of their portfolio LONDON, X0 429,719429.7k $22.8m $22.8m 0.03% Added +403.7k +403,724
63 WASATCH ADVISORS LP 0.12% of their portfolio SALT LAKE CITY, UT 418,147418.1k $22.2m $22.2m 0.12% Reduced -78.0k -77,975
64 BNP PARIBAS FINANCIAL MARKETS 0.02% of their portfolio PARIS, I0 410,478410.5k $21.8m $21.8m 0.02% Reduced -138.5k -138,525
65 Meridiem Capital Partners LP 1.47% of their portfolio DALLAS, TX 382,424382.4k $20.3m $20.3m 1.47% New
66 PRIMECAP MANAGEMENT CO/CA/ 0.02% of their portfolio PASADENA, CA 378,400378.4k $20.1m $20.1m 0.02% Reduced -100.9k -100,900
67 Avidity Partners Management LP 3.78% of their portfolio DALLAS, TX 355,000355.0k $18.9m $18.9m 3.78% Added +2.0k +2,000
68 Swiss National Bank 0.01% of their portfolio ZURICH, V8 354,380354.4k $18.8m $18.8m 0.01% Reduced -167.5k -167,500
69 Rhenman & Partners Asset Management AB 2.35% of their portfolio Stockholm, V7 350,000350.0k $18.6m $18.6m 2.35% Reduced -90.0k -90,000
70 HSBC HOLDINGS PLC 0.01% of their portfolio LONDON, X0 347,177347.2k $18.4m $18.4m 0.01% Reduced -1.1k -1,062
71 Candriam S.C.A. 0.11% of their portfolio STRASSEN, N4 345,399345.4k $18.4m $18.4m 0.11% Reduced -11.6k -11,576
72 Legal & General Group Plc 0.00% of their portfolio London, X0 344,069344.1k $18.3m $18.3m 0.00% Reduced -91.6k -91,562
73 Skandinaviska Enskilda Banken AB (publ) 0.08% of their portfolio STOCKHOLM, V7 332,180332.2k $17.6m $17.6m 0.08% Reduced -37.5k -37,549
74 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 329,176329.2k $17.5m $17.5m 0.00% Added +225.9k +225,890
75 Granahan Investment Management, LLC 0.70% of their portfolio WALTHAM, MA 322,507322.5k $17.1m $17.1m 0.70% Reduced -15.4k -15,368
76 T. Rowe Price Investment Management, Inc. 0.01% of their portfolio BALTIMORE, MD 322,406322.4k $17.1m $17.1m 0.01% Reduced -2.6m -2,596,623
77 Schonfeld Strategic Advisors LLC 0.13% of their portfolio NEW YORK, NY 319,311319.3k $17.0m $17.0m 0.13% Added +299.0k +299,041
78 California Public Employees Retirement System 0.01% of their portfolio Sacramento, CA 313,346313.3k $16.7m $16.7m 0.01% Added +80.0k +79,988
79 Polar Capital Holdings Plc 0.09% of their portfolio London, X0 306,932306.9k $16.3m $16.3m 0.09% Added +10.7k +10,715
80 Iron Triangle Partners LP 2.52% of their portfolio Cos Cob, CT 300,000300.0k $15.9m $15.9m 2.52% New
81 SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 0.62% of their portfolio Boston, MA 299,985300.0k $15.9m $15.9m 0.62% New
82 SEI INVESTMENTS CO 0.02% of their portfolio OAKS, PA 296,323296.3k $15.7m $15.7m 0.02% Added +73.9k +73,916
83 WORLDQUANT MILLENNIUM ADVISORS LLC 0.08% of their portfolio NEW YORK, NY 294,199294.2k $15.6m $15.6m 0.08% Reduced -60.1k -60,137
84 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 286,764286.8k $15.2m $15.2m 0.00% Reduced -91.9k -91,887
85 Bellevue Group AG 0.33% of their portfolio ZURICH, V8 284,201284.2k $15.1m $15.1m 0.33% Reduced -294.9k -294,873
86 EULAV Asset Management 0.35% of their portfolio SARASOTA, FL 283,000283.0k $15.0m $15.0m 0.35% Reduced -52.0k -52,000
87 MACQUARIE GROUP LTD 0.02% of their portfolio Sydney, NSW 2000, C3 280,727280.7k $14.9m $14.9m 0.02% Added +21.1k +21,068
88 Baird Financial Group, Inc. 0.03% of their portfolio MILWAUKEE, WI 280,348280.3k $14.9m $14.9m 0.03% Reduced -30.2k -30,218
89 GAGNON SECURITIES LLC 3.01% of their portfolio New York, NY 278,789278.8k $14.8m $14.8m 3.01% Added +8.1k +8,125
90 Empire Life Investments Inc. 0.91% of their portfolio Toronto, A6 268,909268.9k $14.3m $14.3m 0.91% Reduced -25.0k -24,969
91 FACTORY MUTUAL INSURANCE CO 0.15% of their portfolio WALTHAM, MA 253,500253.5k $13.5m $13.5m 0.15% Unchanged
92 ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio Berwyn, PA 248,535248.5k $13.2m $13.2m 0.00% Added +2.2k +2,182
93 THOMPSON INVESTMENT MANAGEMENT, INC. 1.80% of their portfolio MADISON, WI 239,658239.7k $12.7m $12.7m 1.80% Reduced -12.3k -12,297
94 CITIGROUP INC 0.01% of their portfolio NEW YORK, NY 233,162233.2k $12.4m $12.4m 0.01% Reduced -1.0m -1,048,743
95 Eagle Health Investments LP 2.93% of their portfolio Greenwich, CT 223,750223.8k $11.9m $11.9m 2.93% Reduced -164.9k -164,900
96 FRONTIER CAPITAL MANAGEMENT CO LLC 0.11% of their portfolio Boston, MA 218,445218.4k $11.6m $11.6m 0.11% Reduced -644 -644
97 Freestone Grove Partners LP 0.09% of their portfolio San Francisco, CA 214,411214.4k $11.4m $11.4m 0.09% New
98 DNB Asset Management AS 0.05% of their portfolio Oslo, Q8 213,568213.6k $11.3m $11.3m 0.05% Reduced -32.2k -32,191
99 Sofinnova Investments, Inc. 0.75% of their portfolio Menlo Park, CA 208,300208.3k $11.1m $11.1m 0.75% New
100 EDMOND DE ROTHSCHILD HOLDING S.A. 0.18% of their portfolio CHAMBESY, V8 208,000208.0k $11.1m $11.1m 0.18% Reduced -79.6k -79,648