Vault-13

ENGENE HOLDINGS INC

COM · CUSIP 29286M105

58 institutional holders +21 vs Q3 2025
58,789,54358.8m shares reported held*
$530.8mreported value*
25 new 17 added 8 reduced 6 sold out net bought ≈ $159.2m (+17.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $9.03.

Trends to Q4 2025

Institutional holders

Managers reporting a position, each quarter

0204060Q4 23: 12Q1 24: 32Q2 24: 31Q3 24: 31Q4 24: 35Q1 25: 32Q2 25: 37Q3 25: 37Q4 25: 5858Q4 23Q2 24Q4 24Q2 25Q4 25
Numbers
QuarterHolders
Q4 202312
Q1 202432
Q2 202431
Q3 202431
Q4 202435
Q1 202532
Q2 202537
Q3 202537
Q4 202558

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
50050Q1 24: 25 bought or addedQ1 24: 5 cut or sold outQ2 24: 14 bought or addedQ2 24: 13 cut or sold outQ2 24Q3 24: 16 bought or addedQ3 24: 10 cut or sold outQ4 24: 21 bought or addedQ4 24: 14 cut or sold outQ4 24Q1 25: 9 bought or addedQ1 25: 13 cut or sold outQ2 25: 13 bought or addedQ2 25: 12 cut or sold outQ2 25Q3 25: 14 bought or addedQ3 25: 15 cut or sold outQ4 25: 42 bought or addedQ4 25: 14 cut or sold outQ4 25
Numbers
QuarterBought or addedCut or sold out
Q1 2024255
Q2 20241413
Q3 20241610
Q4 20242114
Q1 2025913
Q2 20251312
Q3 20251415
Q4 20254214

Biggest buyers

PERCEPTIVE ADVISORS LLC Added +3,771,840+3.8m
Siren, L.L.C. New +3,336,264+3.3m
Deep Track Capital, LP Added +2,138,219+2.1m
Nextech Invest Ltd. New +2,124,943+2.1m
JANUS HENDERSON GROUP PLC New +1,900,000+1.9m
Cormorant Asset Management, LP Added +1,676,405+1.7m
MILLENNIUM MANAGEMENT LLC Added +1,479,018+1.5m
MPM BIOIMPACT LLC Added +1,310,599+1.3m
Polar Capital Holdings Plc New +1,142,982+1.1m
EVENTIDE ASSET MANAGEMENT, LLC New +950,000+950.0k

Biggest sellers

Kynam Capital Management, LP Reduced -3,501,192-3.5m
Frazier Life Sciences Management, L.P. Sold out -1,157,380-1.2m
ADAGE CAPITAL PARTNERS GP, L.L.C. Sold out -1,000,000-1.0m
BANK OF AMERICA CORP /DE/ Sold out -647,192-647.2k
Point72 Asset Management, L.P. Reduced -646,602-646.6k
SPHERA FUNDS MANAGEMENT LTD. Sold out -504,409-504.4k
Venrock Adviser, LLC Reduced -275,000-275.0k
CITADEL ADVISORS LLC Reduced -32,987-33.0k
Hudson Bay Capital Management LP Sold out -11,074-11.1k
TORONTO DOMINION BANK Sold out -10,000-10.0k

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
PERCEPTIVE ADVISORS LLC 13G · passive investor no change · filed 2026-08-14 10.0% no change 6.9m 2026-08-14
BML Investment Partners, L.P. 13G · passive investor +2.1 pts · filed 2026-05-14 9.9% +2.1 pts 6.7m 2026-05-14
Deep Track Capital, LP 13G · passive investor +2.3 pts · filed 2025-11-18 6.7% +2.3 pts 4.3m 2025-11-18
Invus Global Management, LLC 13G · passive investor new · filed 2026-01-27 6.3% new 4.2m 2026-01-27
ACORN BIOVENTURES, L.P. 13G · passive investor new · filed 2026-07-22 5.0% new 3.4m 2026-07-22

Fell to 5% or below in the last year: Venrock Healthcare Capital Partners III, L.P. (0.0%, 2026-08-14), Cormorant Asset Management, LP (0.0%, 2026-05-15), Kynam Capital Management, LP (2.2%, 2026-02-17)

Holders, Q4 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FCPM III SERVICES B.V. 11.40% of their portfolio NAARDEN, P7 9,632,5619.6m $87.0m $87.0m 11.40% Unchanged
2 PERCEPTIVE ADVISORS LLC 0.97% of their portfolio NEW YORK, NY 5,869,0765.9m $53.0m $53.0m 0.97% Added +3.8m +3,771,840
3 Venrock Adviser, LLC 2.13% of their portfolio NEW YORK, NY 4,771,4144.8m $43.1m $43.1m 2.13% Reduced -275.0k -275,000
4 Deep Track Capital, LP 0.90% of their portfolio GREENWICH, CT 4,377,5724.4m $39.5m $39.5m 0.90% Added +2.1m +2,138,219
5 Cormorant Asset Management, LP 2.05% of their portfolio BOSTON, MA 4,000,0004.0m $36.1m $36.1m 2.05% Added +1.7m +1,676,405
6 Blue Owl Capital Holdings LP 9.37% of their portfolio New York, NY 3,360,9373.4m $30.3m $30.3m 9.37% Added +82.8k +82,831
7 Siren, L.L.C. 0.90% of their portfolio New York, NY 3,336,2643.3m $30.1m $30.1m 0.90% New
8 BRAIDWELL LP 0.90% of their portfolio STAMFORD, CT 3,131,3193.1m $28.3m $28.3m 0.90% Added +865.0k +865,000
9 Nextech Invest Ltd. 1.85% of their portfolio Zurich, V8 2,124,9432.1m $19.2m $19.2m 1.85% New
10 JANUS HENDERSON GROUP PLC 0.01% of their portfolio LONDON, X0 1,900,0001.9m $17.1m $17.1m 0.01% New
11 MPM BIOIMPACT LLC 1.90% of their portfolio BOSTON, MA 1,840,8981.8m $16.6m $16.6m 1.90% Added +1.3m +1,310,599
12 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 1,499,5201.5m $13.5m $13.5m 0.01% Added +1.5m +1,479,018
13 Kynam Capital Management, LP 0.88% of their portfolio PRINCETON, NJ 1,492,8981.5m $13.5m $13.5m 0.88% Reduced -3.5m -3,501,192
14 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 1,388,0001.4m $12.5m $12.5m 0.00% Added +350.0k +350,000
15 Polar Capital Holdings Plc 0.05% of their portfolio London, X0 1,142,9821.1m $10.3m $10.3m 0.05% New
16 Vestal Point Capital, LP 0.35% of their portfolio NEW YORK, NY 1,055,0001.1m $9.5m $9.5m 0.35% Added +685.0k +685,000
17 EVENTIDE ASSET MANAGEMENT, LLC 0.13% of their portfolio Boston, MA 950,000950.0k $8.6m $8.6m 0.13% New
18 Omega Fund Management, LLC 2.76% of their portfolio Boston, MA 876,357876.4k $7.9m $7.9m 2.76% Added +350.0k +350,000
19 SR One Capital Management, LP 0.96% of their portfolio Redwood City, CA 747,750747.8k $6.8m $6.8m 0.96% Unchanged
20 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 718,485718.5k $6.5m $6.5m 0.00% Added +283.2k +283,194
21 Affinity Asset Advisors, LLC 0.42% of their portfolio NEW YORK, NY 643,370643.4k $5.8m $5.8m 0.42% Added +566.4k +566,370
22 Point72 Asset Management, L.P. 0.01% of their portfolio STAMFORD, CT 561,797561.8k $5.1m $5.1m 0.01% Reduced -646.6k -646,602
23 Eversept Partners, LP 0.23% of their portfolio NEW YORK, NY 455,835455.8k $4.1m $4.1m 0.23% New
24 Privium Fund Management B.V. 0.59% of their portfolio AMSTERDAM, P7 352,087352.1k $3.2m $3.2m 0.59% New
25 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 343,928343.9k $3.1m $3.1m 0.00% Unchanged
26 ADAR1 Capital Management, LLC 0.21% of their portfolio AUSTIN, TX 303,686303.7k $2.7m $2.7m 0.21% New
27 Monashee Investment Management LLC 1.50% of their portfolio Boston, MA 295,000295.0k $2.7m $2.7m 1.50% New
28 Woodline Partners LP 0.01% of their portfolio San Francisco, CA 250,000250.0k $2.3m $2.3m 0.01% New
29 Elmind Capital, LP 0.56% of their portfolio NEW YORK, NY 210,000210.0k $1.9m $1.9m 0.56% First filing
30 DAFNA Capital Management LLC 0.34% of their portfolio LOS ANGELES, CA 163,645163.6k $1.5m $1.5m 0.34% New
31 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 161,512161.5k $1.5m $1.5m 0.00% New
32 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 147,889147.9k $1.3m $1.3m 0.00% Added +287 +287
33 Deeter Investments LLP 0.18% of their portfolio AUSTIN, TX 90,00090.0k $812.7k $812.7k 0.18% First filing
34 KENNEDY CAPITAL MANAGEMENT LLC 0.01% of their portfolio ST LOUIS, MO 76,76576.8k $693.2k $693.2k 0.01% New
35 HRT FINANCIAL LP 0.00% of their portfolio NEW YORK, NY 64,38064.4k $581.0k $581.0k 0.00% New
36 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 56,45456.5k $509.8k $509.8k 0.00% New
37 Quadrature Capital Ltd 0.00% of their portfolio LONDON, X0 48,58348.6k $438.7k $438.7k 0.00% New
38 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 35,87735.9k $324.0k $324.0k 0.00% New
39 Virtus Investment Advisers, LLC 0.08% of their portfolio HARTFORD, CT 31,44531.4k $283.9k $283.9k 0.08% New
40 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 30,08530.1k $271.7k $271.7k 0.00% Reduced -210 -210
41 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 29,01829.0k $262.0k $262.0k 0.00% Unchanged
42 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 25,38325.4k $229.2k $229.2k 0.00% Reduced -33.0k -32,987
43 Pale Fire Capital SE 0.03% of their portfolio Prague, 2N 24,00424.0k $216.8k $216.8k 0.03% Added +6.8k +6,750
44 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 23,98024.0k $216.5k $216.5k 0.00% New
45 XTX Topco Ltd 0.01% of their portfolio LONDON, X0 23,92223.9k $216.0k $216.0k 0.01% New
46 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 20,78220.8k $187.7k $187.7k 0.00% New
47 RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio ST. PETERSBURG, FL 19,96020.0k $180.2k $180.2k 0.00% Added +10.0k +9,960
48 TWO SIGMA ADVISERS, LP 0.00% of their portfolio NEW YORK, NY 17,30017.3k $156.2k $156.2k 0.00% New
49 Schonfeld Strategic Advisors LLC 0.00% of their portfolio NEW YORK, NY 16,64516.6k $150.3k $150.3k 0.00% Reduced -8.4k -8,425
50 Jump Financial, LLC 0.00% of their portfolio Chicago, IL 13,40013.4k $121.0k $121.0k 0.00% New
51 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 11,21711.2k $101.3k $101.3k 0.00% Reduced -6.7k -6,693
52 PFS Partners, LLC 0.05% of their portfolio MINE HILL, NJ 11,00011.0k $99.3k $99.3k 0.05% Added +2.0k +2,000
53 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 7,9157.9k $71.0k $71.0k 0.00% Unchanged
54 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 2,6142.6k $23.6k $23.6k 0.00% New
55 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 1,6881.7k $15.2k $15.2k 0.00% Added +1.7k +1,687
56 UBS Group AG 0.00% of their portfolio ZURICH, V8 1,5971.6k $14.4k $14.4k 0.00% New
57 MAI Capital Management 0.00% of their portfolio INDEPENDENCE, OH 776776 $7.0k $7.0k 0.00% Unchanged
58 SBI Securities Co., Ltd. 0.00% of their portfolio TOKYO, M0 2828 $253 $253 0.00% Reduced -3 -3