CLIMB BIO INC CLYM
COM · Common Stock · CUSIP 28658R106
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWellesley Hills, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($180.0k this quarter). Holder counts are more reliable. Shares outstanding: 67.8m as of 2025-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.24.
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 23 |
| Q4 2022 | 21 |
| Q1 2023 | 20 |
| Q2 2023 | 23 |
| Q3 2023 | 24 |
| Q4 2023 | 24 |
| Q1 2024 | 22 |
| Q2 2024 | 48 |
| Q3 2024 | 72 |
| Q4 2024 | 81 |
| Q1 2025 | 77 |
| Q2 2025 | 70 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2023 | 8 | 9 |
| Q4 2023 | 8 | 11 |
| Q1 2024 | 8 | 7 |
| Q2 2024 | 40 | 9 |
| Q3 2024 | 57 | 14 |
| Q4 2024 | 46 | 30 |
| Q1 2025 | 33 | 35 |
| Q2 2025 | 38 | 48 |
Biggest buyers
| CANTOR FITZGERALD, L. P. | Added | +503.1k |
| Alyeska Investment Group, L.P. | New | +485.4k |
| NAN FUNG TRINITY (HK) LTD | New | +463.7k |
| MILLENNIUM MANAGEMENT LLC | Added | +416.7k |
| Shay Capital LLC | Added | +215.0k |
| JANE STREET GROUP, LLC | New | +148.2k |
| Y-Intercept (Hong Kong) Ltd | New | +128.0k |
| Stonepine Capital Management, LLC | New | +116.1k |
| GOLDMAN SACHS GROUP INC | Added | +80.6k |
| Cubist Systematic Strategies, LLC | New | +62.2k |
Biggest sellers
| BlackRock, Inc. | Reduced | -1.4m |
| Nan Fung Group Holdings Ltd | Sold out | -463.7k |
| Schonfeld Strategic Advisors LLC | Sold out | -442.7k |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | -362.1k |
| STATE STREET CORP | Reduced | -275.4k |
| Allostery Investments LP | Sold out | -245.0k |
| CITIGROUP INC | Reduced | -238.2k |
| Ikarian Capital, LLC | Sold out | -175.1k |
| VANGUARD GROUP INC | Reduced | -171.3k |
| NORTHERN TRUST CORP | Reduced | -159.5k |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
RA CAPITAL MANAGEMENT, L.P.
13D · may seek influence
no change · filed 2026-07-07
Stated purposeItem 4 of the Statement is hereby amended and supplemented as follows: On June 29, 2026 Dr. Breanna Celebi (O'Reilly), an Analyst of RA Capital, was appointed to the Board of Directors of the Issuer as the designee of RA Capital, replacing Dr. Andrew Levin, who resigned from the Board of Directors effective June 29, 2026. Full filing |
33.0% |
| FMR LLC 13G · institution new · filed 2026-07-08 | 11.9% |
| Pontifax Management 4 G.P. (2015) Ltd. 13G · passive investor new · filed 2025-09-18 | 7.7% |
| Flynn James E 13G · passive investor new · filed 2026-10-28 | 5.2% |
| BlackRock, Inc. 13G · institution new · filed 2026-10-27 | 5.0% |
Fell to 5% or below in the last year: MPM BioImpact LLC (0.0%, 2026-08-14)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 1 | $50.0m | 1 | $9.0k | — |
| Q3 2024 | 0 | — | 2 | $3.5m | $9.7k |
| Q4 2024 | 0 | — | 1 | $2.5k | $2.5k |
| Q1 2025 | 0 | — | 1 | $1.6k | $1.6k |
| Q2 2025 | 0 | — | 2 | $26.7k | $26.7k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-06-30 | Brennan Aoife President and CEO, director | Sold plan | $25.2k20.6k shares |
| 2025-06-20 | Pimblett Emily SVP, Finance & CAO | Sold plan | $1.5k1.2k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 0.66% of their portfolio | 31.4m $39.0m | Unchanged |
| CANTOR FITZGERALD, L. P. 0.08% of their portfolio | 2.5m $3.1m | Added +503.1k |
| CITIGROUP INC 0.00% of their portfolio | 1.6m $2.0m | Reduced -238.2k |
| Affinity Asset Advisors, LLC 0.28% of their portfolio | 1.5m $1.9m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.3m $1.7m | Reduced -171.3k |
| Deep Track Capital, LP 0.04% of their portfolio | 1.0m $1.3m | Unchanged |
| Kynam Capital Management, LP 0.14% of their portfolio | 1.0m $1.3m | Reduced -18.7k |
| TANG CAPITAL MANAGEMENT LLC 0.06% of their portfolio | 1.0m $1.2m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 878.0k $1.1m | Reduced -1.4m |
| DIADEMA PARTNERS LP 0.54% of their portfolio | 702.1k $870.6k | Added +32.3k |
| Peapod Lane Capital LLC 0.69% of their portfolio | 555.7k $689.0k | Added +1.9k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 548.0k $680.0k | Reduced -37.8k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 495.5k $614.4k | Reduced -18.9k |
| Alyeska Investment Group, L.P. 0.00% of their portfolio | 485.4k $601.9k | New |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 480.1k $595.3k | Added +416.7k |
| NAN FUNG TRINITY (HK) LTD 0.07% of their portfolio | 463.7k $574.9k | New |
| Shay Capital LLC 0.12% of their portfolio | 415.0k $514.6k | Added +215.0k |
| UBS Group AG 0.00% of their portfolio | 382.5k $474.3k | Added +257 |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 311.7k $386.7k | Reduced -362.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 210.1k $260.6k | Reduced -96.3k |
| SPHERA FUNDS MANAGEMENT LTD. 0.07% of their portfolio | 209.8k $260.2k | Reduced -32.1k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 201.3k $249.6k | Added +80.6k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 179.6k $222.7k | Reduced -75.5k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 148.2k $183.7k | New |
| Persistent Asset Partners Ltd 0.16% of their portfolio | 145.2k $180.0k | Reduced -581 |
| NORTHERN TRUST CORP 0.00% of their portfolio | 141.4k $175.4k | Reduced -159.5k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 138.4k $171.6k | Added +55.6k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 134.3k $166.5k | Unchanged |
| Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio | 128.0k $158.7k | New |
| ADAR1 Capital Management, LLC 0.02% of their portfolio | 119.3k $148.0k | Unchanged |
| Stonepine Capital Management, LLC 0.14% of their portfolio | 116.1k $144.0k | New |
| STATE STREET CORP 0.00% of their portfolio | 103.1k $127.8k | Reduced -275.4k |
| MORGAN STANLEY 0.00% of their portfolio | 99.5k $123.3k | Reduced -77.5k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 94.9k $117.7k | Reduced -19.1k |
| TD Asset Management Inc 0.00% of their portfolio | 89.4k $110.9k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 62.4k $77.3k | Added +19.9k |
| Cubist Systematic Strategies, LLC 0.00% of their portfolio | 62.2k $77.1k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 38.9k $48.2k | Reduced -1.2k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 36.7k $45.6k | New |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 34.3k $42.5k | New |
| BARCLAYS PLC 0.00% of their portfolio | 29.4k $36.4k | Reduced -29.4k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 28.9k $35.8k | Added +7.1k |
| Jain Global LLC 0.00% of their portfolio | 25.7k $31.9k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 19.6k $24.4k | New |
| HRT FINANCIAL LP 0.00% of their portfolio | 18.5k $22.0k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 14.1k $17.5k | Added +6.0k |
| Point72 Asia (Singapore) Pte. Ltd. 0.00% of their portfolio | 14.1k $17.5k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 13.8k $17.0k | Reduced -993 |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 13.6k $16.8k | Added +88 |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 13.3k $16.2k | Reduced -3.4k |
| Chicago Partners Investment Group LLC 0.00% of their portfolio | 12.8k $19.0k | Reduced -2.1k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 12.4k $15.4k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 7.7k $9.5k | Added +1.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 7.6k $9.5k | Reduced -29.7k |
| FMR LLC 0.00% of their portfolio | 7.6k $9.5k | Added +5.0k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 5.7k $8.0k | Added +1.1k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 2.6k $3.2k | Added +361 |
| CWM, LLC 0.00% of their portfolio | 2.4k $3.0k | Added +387 |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.6k $2.0k | Unchanged |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 573 $711 | New |
| Point72 (DIFC) Ltd 0.00% of their portfolio | 421 $522 | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 295 $360 | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 244 $303 | Reduced -17.2k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 200 $248 | New |
| Essential Partners LLC 0.00% of their portfolio | 63 $78 | First filing |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 51 $63 | Added +42 |
| True Wealth Design, LLC 0.00% of their portfolio | 19 $24 | Added +7 |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 12 $15 | Added +2 |
| Clearstead Advisors, LLC 0.00% of their portfolio | 11 $14 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. — of their portfolio | 0 $0 | Unchanged |