CLIMB BIO INC CLYM
COM · Common Stock · CUSIP 28658R106
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWellesley Hills, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.9k this quarter). Holder counts are more reliable. Shares outstanding: 67.5m as of 2025-03-21, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.22.
Trends to Q1 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 23 |
| Q4 2022 | 21 |
| Q1 2023 | 20 |
| Q2 2023 | 23 |
| Q3 2023 | 24 |
| Q4 2023 | 24 |
| Q1 2024 | 22 |
| Q2 2024 | 48 |
| Q3 2024 | 72 |
| Q4 2024 | 81 |
| Q1 2025 | 77 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2023 | 9 | 6 |
| Q3 2023 | 8 | 9 |
| Q4 2023 | 8 | 11 |
| Q1 2024 | 8 | 7 |
| Q2 2024 | 40 | 9 |
| Q3 2024 | 57 | 14 |
| Q4 2024 | 46 | 30 |
| Q1 2025 | 33 | 35 |
Biggest buyers
| CITIGROUP INC | Added | +1.8m |
| CANTOR FITZGERALD, L. P. | Added | +1.3m |
| TANG CAPITAL MANAGEMENT LLC | New | +1.0m |
| Affinity Asset Advisors, LLC | Added | +1.0m |
| Peapod Lane Capital LLC | New | +553.8k |
| Kynam Capital Management, LP | Added | +500.0k |
| DIADEMA PARTNERS LP | Added | +295.4k |
| Shay Capital LLC | New | +200.0k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +142.1k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | New | +134.3k |
Biggest sellers
| JANUS HENDERSON GROUP PLC | Sold out | -3.2m |
| SAMSARA BIOCAPITAL, LLC | Sold out | -2.6m |
| Boxer Capital Management, LLC | Reduced | -2.5m |
| BANK OF AMERICA CORP /DE/ | Reduced | -996.4k |
| Ally Bridge Group (NY) LLC | Sold out | -760.2k |
| Parkman Healthcare Partners LLC | Sold out | -290.5k |
| SEGALL BRYANT & HAMILL, LLC | Sold out | -124.0k |
| SUPERSTRING CAPITAL MANAGEMENT LP | Sold out | -98.2k |
| Mariner, LLC | Reduced | -81.1k |
| Walleye Capital LLC | Sold out | -62.0k |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
RA CAPITAL MANAGEMENT, L.P.
13D · may seek influence
no change · filed 2026-07-07
Stated purposeItem 4 of the Statement is hereby amended and supplemented as follows: On June 29, 2026 Dr. Breanna Celebi (O'Reilly), an Analyst of RA Capital, was appointed to the Board of Directors of the Issuer as the designee of RA Capital, replacing Dr. Andrew Levin, who resigned from the Board of Directors effective June 29, 2026. Full filing |
33.0% |
| FMR LLC 13G · institution new · filed 2026-07-08 | 11.9% |
| Pontifax Management 4 G.P. (2015) Ltd. 13G · passive investor new · filed 2025-09-18 | 7.7% |
| Flynn James E 13G · passive investor new · filed 2026-10-28 | 5.2% |
| BlackRock, Inc. 13G · institution new · filed 2026-10-27 | 5.0% |
Fell to 5% or below in the last year: MPM BioImpact LLC (0.0%, 2026-08-14)
Insider purchases and sales in Q1 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 0 | — | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 1 | $50.0m | 1 | $9.0k | — |
| Q3 2024 | 0 | — | 2 | $3.5m | $9.7k |
| Q4 2024 | 0 | — | 1 | $2.5k | $2.5k |
| Q1 2025 | 0 | — | 1 | $1.6k | $1.6k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-03-20 | Pimblett Emily SVP, Finance & CAO | Sold plan | $1.6k1.2k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2025
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 0.64% of their portfolio | 31.4m $38.3m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 2.3m $2.8m | Reduced -9.8k |
| CANTOR FITZGERALD, L. P. 0.09% of their portfolio | 2.0m $2.4m | Added +1.3m |
| CITIGROUP INC 0.00% of their portfolio | 1.9m $2.3m | Added +1.8m |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.5m $1.8m | Reduced -3.7k |
| Affinity Asset Advisors, LLC 0.29% of their portfolio | 1.5m $1.8m | Added +1.0m |
| Kynam Capital Management, LP 0.11% of their portfolio | 1.0m $1.3m | Added +500.0k |
| Deep Track Capital, LP 0.04% of their portfolio | 1.0m $1.3m | Unchanged |
| TANG CAPITAL MANAGEMENT LLC 0.07% of their portfolio | 1.0m $1.2m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 673.8k $822.3k | Added +13.0k |
| DIADEMA PARTNERS LP 0.65% of their portfolio | 669.8k $817.2k | Added +295.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 585.7k $716.0k | Reduced -42.9k |
| Peapod Lane Capital LLC 0.76% of their portfolio | 553.8k $675.7k | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 514.4k $627.6k | Added +142.1k |
| Nan Fung Group Holdings Ltd 0.46% of their portfolio | 463.7k $565.7k | Unchanged |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 442.7k $540.0k | Reduced -22.4k |
| UBS Group AG 0.00% of their portfolio | 382.2k $466.3k | Reduced -33.1k |
| STATE STREET CORP 0.00% of their portfolio | 378.5k $461.8k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 306.4k $373.8k | Added +14.6k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 300.9k $367.1k | Reduced -13.0k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 255.1k $311.2k | Added +17.4k |
| Allostery Investments LP 0.43% of their portfolio | 245.0k $298.9k | Unchanged |
| SPHERA FUNDS MANAGEMENT LTD. 0.07% of their portfolio | 241.9k $295.2k | Reduced -10.0k |
| Shay Capital LLC 0.07% of their portfolio | 200.0k $244.0k | New |
| MORGAN STANLEY 0.00% of their portfolio | 177.0k $215.9k | Reduced -49.9k |
| Ikarian Capital, LLC 0.07% of their portfolio | 175.1k $213.6k | Unchanged |
| Persistent Asset Partners Ltd 0.16% of their portfolio | 145.8k $177.8k | Unchanged |
| Boxer Capital Management, LLC 0.05% of their portfolio | 145.0k $176.9k | Reduced -2.5m |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 134.3k $163.8k | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 120.7k $147.3k | Reduced -4.6k |
| ADAR1 Capital Management, LLC 0.03% of their portfolio | 119.3k $145.6k | Added +71.2k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 114.0k $139.1k | Added +2.3k |
| TD Asset Management Inc 0.00% of their portfolio | 89.4k $109.1k | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 82.8k $101.0k | Added +16.3k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 70.1k $85.5k | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 64.9k $79.2k | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 63.4k $77.3k | New |
| BARCLAYS PLC 0.00% of their portfolio | 58.7k $71.7k | Added +8.9k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.00% of their portfolio | 53.7k $65.5k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 42.5k $51.9k | Added +28.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 40.1k $49.0k | Added +1.2k |
| Nuveen, LLC 0.00% of their portfolio | 39.0k $47.6k | First filing |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 37.3k $45.5k | Reduced -996.4k |
| XTX Topco Ltd 0.00% of their portfolio | 27.7k $33.7k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 24.8k $30.2k | Reduced -7.1k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 21.8k $26.6k | Reduced -3.4k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 21.0k $25.6k | Added +7.3k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 17.6k $21.5k | Added +786 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 17.4k $21.3k | Added +387 |
| Mariner, LLC 0.00% of their portfolio | 17.2k $21.0k | Reduced -81.1k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 16.7k $21.4k | Reduced -22 |
| Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio | 15.2k $18.6k | New |
| Chicago Partners Investment Group LLC 0.00% of their portfolio | 15.0k $18.1k | Reduced -6.7k |
| SG Americas Securities, LLC 0.00% of their portfolio | 14.8k $18.0k | Reduced -16.2k |
| Corebridge Financial, Inc. 0.00% of their portfolio | 14.4k $17.6k | Reduced -213 |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 13.5k $16.4k | Reduced -770 |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 10.5k $12.8k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 8.1k $9.9k | Added +2.5k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 5.9k $7.2k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 5.8k $7.0k | First filing |
| STRS OHIO 0.00% of their portfolio | 5.3k $6.5k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 4.6k $6.0k | Reduced -96 |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.0k $3.6k | Unchanged |
| FMR LLC 0.00% of their portfolio | 2.6k $3.2k | Reduced -10.9k |
| Legal & General Group Plc 0.00% of their portfolio | 2.6k $3.2k | Unchanged |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 2.2k $2.9k | Added +9 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 2.2k $2.6k | Unchanged |
| CWM, LLC 0.00% of their portfolio | 2.0k $2.0k | Added +2.0k |
| Militia Capital Partners, LP 0.00% of their portfolio | 1.7k $2.1k | Unchanged |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 1.6k $2.0k | Added +204 |
| AMALGAMATED BANK 0.00% of their portfolio | 1.0k $1.0k | Added +764 |
| Sterling Capital Management LLC 0.00% of their portfolio | 479 $584 | Reduced -462 |
| COLDSTREAM CAPITAL MANAGEMENT INC 0.00% of their portfolio | 336 $410 | New |
| True Wealth Design, LLC 0.00% of their portfolio | 12 $15 | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 10 $12 | Unchanged |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 9 $11 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. — of their portfolio | 0 $0 | Unchanged |