DYNE THERAPEUTICS INC DYN
COM · Common Stock · CUSIP 26818M108
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWaltham, MA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 61.0m as of 2023-07-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $11.25. Options: 3 managers hold calls ($45.9k notional), 3 hold puts ($178.9k).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 102 |
| Q4 2022 | 114 |
| Q1 2023 | 128 |
| Q2 2023 | 119 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 53 | 43 |
| Q1 2023 | 76 | 35 |
| Q2 2023 | 72 | 52 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $517.0k | $10.0k | 0.02 |
| Q4 2022 | $860.2k | $48.7k | 0.06 |
| Q1 2023 | $176.2k | $4.6k | 0.03 |
| Q2 2023 | $45.9k | $178.9k | 3.90 |
Biggest buyers
| Venrock Adviser, LLC | New | +2.2m |
| STATE STREET CORP | Added | +1.2m |
| VANGUARD GROUP INC | Added | +942.0k |
| ARMISTICE CAPITAL, LLC | New | +912.0k |
| BlackRock Inc. | Added | +703.0k |
| GOLDMAN SACHS GROUP INC | Added | +515.1k |
| Polar Capital Holdings Plc | New | +500.0k |
| Sofinnova Investments, Inc. | New | +441.0k |
| Nantahala Capital Management, LLC | Added | +414.3k |
| Woodline Partners LP | New | +382.6k |
Biggest sellers
| EcoR1 Capital, LLC | Reduced | -1.5m |
| WASATCH ADVISORS LP | Reduced | -667.7k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Reduced | -500.0k |
| Point72 Asset Management, L.P. | Reduced | -492.6k |
| HHLR ADVISORS, LTD. | Sold out | -478.4k |
| CITADEL ADVISORS LLC | Reduced | -322.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -280.4k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Reduced | -204.5k |
| MILLENNIUM MANAGEMENT LLC | Sold out | -190.4k |
| FEDERATED HERMES, INC. | Reduced | -180.8k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $43.9k3.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.0k200 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $135.0k12.0k shares |
| CITADEL ADVISORS LLC | Added | $43.9k3.9k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| T. Rowe Price Investment Management, Inc. 13G · institution +2.5 pts · filed 2026-05-15 | 18.7% |
| Janus Henderson Group Ltd. 13G · institution -1.0 pts · filed 2026-08-13 | 7.3% |
| BlackRock, Inc. 13G · institution +1.2 pts · filed 2026-07-28 | 7.0% |
| FMR LLC 13G · institution +1.4 pts · filed 2026-08-06 | 6.8% |
Fell to 5% or below in the last year: Atlas Venture Fund XI, L.P. (2.4%, 2026-08-13), VANGUARD GROUP INC (0.0%, 2026-03-26), RA CAPITAL MANAGEMENT, L.P. (0.0%, 2025-11-14)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 0 | — | — |
| Q1 2022 | 0 | — | 6 | $102.8k | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 1 | $10.0m | 6 | $2.7m | — |
| Q1 2023 | 0 | — | 6 | $772.1k | — |
| Q2 2023 | 0 | — | 6 | $4.9m | $28.6k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-06-15 | Scalzo Richard William Officer | Sold | $120.3k10.0k shares |
| 2023-06-13 | Scalzo Richard William Officer | Sold | $532.9k41.4k shares |
| 2023-06-13 | Farwell Wildon Chief Medical Officer | Sold | $21.1k1.7k shares |
| 2023-06-13 | HIGH SUSANNA GATTI Chief Operating Officer | Sold | $20.2k1.6k shares |
| 2023-06-13 | Beskrovnaya Oxana Chief Scientific Officer | Sold | $18.3k1.5k shares |
| 2023-06-13 | McNeill Jonathan Officer | Sold plan | $15.6k1.3k shares |
| 2023-06-12 | Brumm Joshua T Officer, director | Sold | $2.4m187.7k shares |
| 2023-06-12 | McNeill Jonathan Officer | Sold plan | $13.0k1.0k shares |
| 2023-06-09 | Brumm Joshua T Officer, director | Sold | $1.0m76.6k shares |
| 2023-06-08 | Brumm Joshua T Officer, director | Sold | $806.7k61.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| Atlas Venture Life Science Advisors, LLC 13.84% of their portfolio | 9.9m $111.2m | Unchanged |
| MPM ASSET MANAGEMENT LLC 27.32% of their portfolio | 5.0m $55.7m | Unchanged |
| BlackRock Inc. 0.00% of their portfolio | 3.3m $37.4m | Added +703.0k |
| CITADEL ADVISORS LLC 0.03% of their portfolio | 2.7m $30.4m | Reduced -322.8k |
| Deep Track Capital, LP 1.31% of their portfolio | 2.5m $28.1m | Added +165.3k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.4m $26.9m | Added +942.0k |
| WASATCH ADVISORS LP 0.15% of their portfolio | 2.3m $25.4m | Reduced -667.7k |
| Vida Ventures Advisors, LLC 32.61% of their portfolio | 2.2m $25.0m | Unchanged |
| Venrock Adviser, LLC 3.91% of their portfolio | 2.2m $24.5m | New |
| GOLDMAN SACHS GROUP INC 0.01% of their portfolio | 2.0m $22.6m | Added +515.1k |
| FRANKLIN RESOURCES INC 0.01% of their portfolio | 1.9m $21.5m | Added +21.1k |
| Logos Global Management LP 2.77% of their portfolio | 1.8m $20.0m | Added +80.0k |
| STATE STREET CORP 0.00% of their portfolio | 1.8m $20.0m | Added +1.2m |
| TCG Crossover Management, LLC 3.04% of their portfolio | 1.7m $18.6m | Unchanged |
| BRAIDWELL LP 0.51% of their portfolio | 1.4m $15.5m | Unchanged |
| ARMISTICE CAPITAL, LLC 0.26% of their portfolio | 912.0k $10.3m | New |
| FMR LLC 0.00% of their portfolio | 899.3k $10.1m | Added +81.2k |
| Artal Group S.A. 0.29% of their portfolio | 815.1k $9.2m | Added +282.5k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 800.2k $9.0m | Added +139.6k |
| EcoR1 Capital, LLC 0.24% of their portfolio | 798.7k $9.0m | Reduced -1.5m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 739.2k $8.3m | Added +170.7k |
| Candriam S.C.A. 0.06% of their portfolio | 723.6k $8.1m | Added +90.0k |
| Octagon Capital Advisors LP 1.09% of their portfolio | 692.9k $7.8m | Unchanged |
| Nantahala Capital Management, LLC 0.81% of their portfolio | 593.2k $6.7m | Added +414.3k |
| Assenagon Asset Management S.A. 0.03% of their portfolio | 579.4k $6.5m | Added +540 |
| Vivo Capital, LLC 0.45% of their portfolio | 577.6k $6.5m | Unchanged |
| Ensign Peak Advisors, Inc 0.01% of their portfolio | 511.3k $5.8m | Added +284.7k |
| Polar Capital Holdings Plc 0.04% of their portfolio | 500.0k $5.6m | New |
| AXA S.A. 0.02% of their portfolio | 477.7k $5.4m | Added +53.6k |
| Sofinnova Investments, Inc. 0.33% of their portfolio | 441.0k $5.0m | New |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 428.5k $4.8m | Reduced -492.6k |
| Woodline Partners LP 0.05% of their portfolio | 382.6k $4.3m | New |
| ArrowMark Colorado Holdings LLC 0.05% of their portfolio | 382.4k $4.3m | Added +107.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 380.9k $4.3m | Added +106.5k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 365.8k $4.1m | Added +37.7k |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC 1.03% of their portfolio | 300.8k $3.4m | Reduced -133.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 285.1k $3.2m | Added +57.5k |
| ALGERT GLOBAL LLC 0.12% of their portfolio | 239.1k $2.7m | Added +47.2k |
| NORGES BANK 0.00% of their portfolio | 195.6k $2.2m | Reduced -168.0k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.04% of their portfolio | 175.8k $2.0m | Reduced -849 |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 160.9k $1.8m | Reduced -75.6k |
| Altium Capital Management LLC 1.36% of their portfolio | 155.0k $1.7m | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 150.2k $1.7m | Added +23.4k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 149.0k $1.7m | Added +14.4k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 120.9k $1.4m | Added +66.6k |
| SPHERA FUNDS MANAGEMENT LTD. 0.29% of their portfolio | 119.9k $1.3m | Reduced -99.4k |
| Rafferty Asset Management, LLC 0.01% of their portfolio | 117.3k $1.3m | New |
| MORGAN STANLEY 0.00% of their portfolio | 114.8k $1.3m | Added +1.2k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 111.3k $1.3m | Added +87.7k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 110.6k $1.2m | Added +34.3k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio | 100.0k $1.1m | Reduced -500.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 91.7k $1.0m | Added +19.8k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 82.4k $927.0k | Reduced -180.8k |
| BARCLAYS PLC 0.00% of their portfolio | 82.0k $922.2k | Added +49.9k |
| ACUTA CAPITAL PARTNERS, LLC 0.56% of their portfolio | 73.0k $821.2k | New |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 72.0k $810.0k | Reduced -5.2k |
| Invesco Ltd. 0.00% of their portfolio | 69.0k $776.7k | Reduced -171.9k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 63.9k $719.0k | Added +12.7k |
| Swiss National Bank 0.00% of their portfolio | 63.5k $714.4k | Added +7.2k |
| Integral Health Asset Management, LLC 0.09% of their portfolio | 62.0k $697.5k | Added +5.0k |
| CITIGROUP INC 0.00% of their portfolio | 50.4k $566.9k | Added +45.9k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 40.0k $417.0k | Added +25.0k |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 39.8k $448.0k | Reduced -54.4k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 39.8k $447.5k | Added +5.1k |
| B. Metzler seel. Sohn & Co. AG 0.01% of their portfolio | 37.9k $426.9k | Added +19.0k |
| PUTNAM INVESTMENTS LLC 0.00% of their portfolio | 37.0k $416.8k | Reduced -1.2k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 36.3k $408.6k | Added +30.5k |
| New York Life Investment Management LLC 0.00% of their portfolio | 35.8k $402.5k | Reduced -6.6k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 35.6k $400.6k | Added +8.7k |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 34.5k $388.0k | Added +8.5k |
| Squarepoint Ops LLC 0.00% of their portfolio | 34.1k $383.2k | Added +9.7k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 33.6k $378.5k | Added +9.9k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 32.5k $365.6k | Reduced -126.5k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 29.5k $331.6k | Reduced -1.6k |
| Trexquant Investment LP 0.01% of their portfolio | 27.4k $308.0k | Reduced -15.1k |
| Legal & General Group Plc 0.00% of their portfolio | 24.5k $275.8k | Added +13.8k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 24.3k $273.1k | Reduced -204.5k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 22.9k $258.0k | Added +3.2k |
| UBS Group AG 0.00% of their portfolio | 22.6k $253.9k | Added +21.1k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 22.1k $248.1k | Reduced -110.3k |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 21.7k $243.7k | New |
| CORNERCAP INVESTMENT COUNSEL INC 0.04% of their portfolio | 21.2k $238.9k | New |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 21.1k $234.4k | Added +4.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 21.0k $236.3k | Reduced -29.5k |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 20.5k $230.2k | Added +5.2k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 20.2k $226.9k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 20.0k $225.2k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 17.4k $195.7k | Reduced -2.1k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 17.3k $194.4k | Reduced -9.2k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 16.1k $181.5k | Reduced -3.5k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 13.8k $154.7k | Added +2.1k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 13.3k $149.6k | Reduced -36.2k |
| Redmond Asset Management, LLC 0.05% of their portfolio | 13.2k $148.7k | Unchanged |
| Corton Capital Inc. 0.07% of their portfolio | 13.1k $147.7k | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 12.2k $140.8k | Unchanged |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 12.1k $135.7k | New |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 11.3k $127.8k | Added +11 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 10.9k $124.0k | Reduced -280.4k |
| VIRTUS ADVISERS, LLC 0.06% of their portfolio | 8.8k $98.7k | Added +1.4k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 8.4k $94.5k | Added +7.1k |