DIANTHUS THERAPEUTICS INC DNTH
COM · Common Stock · CUSIP 252828108
Biotechnology company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersNew York, NY
- Websitemagentatx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.9m this quarter). Holder counts are more reliable. Shares outstanding: 29.4m as of 2024-08-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $25.88. Options: 1 managers hold calls ($0 notional), 1 hold puts ($0).
Trends to Q2 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2023 | 31 |
| Q4 2023 | 40 |
| Q1 2024 | 77 |
| Q2 2024 | 75 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2023 | 20 | 7 |
| Q1 2024 | 63 | 10 |
| Q2 2024 | 45 | 47 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2023 | $3.8k | $0 | 0.00 |
| Q4 2023 | $0 | $0 | — |
| Q1 2024 | $0 | $0 | — |
| Q2 2024 | $0 | $0 | — |
Biggest buyers
| BlackRock Inc. | Added | +1.6m |
| VANGUARD GROUP INC | Added | +707.4k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +424.5k |
| STATE STREET CORP | Added | +387.3k |
| BRAIDWELL LP | New | +366.9k |
| Octagon Capital Advisors LP | Added | +366.0k |
| JANUS HENDERSON GROUP PLC | Added | +300.6k |
| Woodline Partners LP | New | +250.3k |
| FMR LLC | Added | +241.4k |
| Avidity Partners Management LP | Added | +199.7k |
Biggest sellers
| MILLENNIUM MANAGEMENT LLC | Sold out | -277.2k |
| Ally Bridge Group (NY) LLC | Sold out | -217.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Sold out | -205.5k |
| Walleye Capital LLC | Sold out | -190.3k |
| Point72 Asset Management, L.P. | Reduced | -177.9k |
| GOLDMAN SACHS GROUP INC | Reduced | -128.3k |
| Soleus Capital Management, L.P. | Sold out | -100.0k |
| JANE STREET GROUP, LLC | Sold out | -82.1k |
| Hudson Bay Capital Management LP | Sold out | -80.0k |
| Qube Research & Technologies Ltd | Reduced | -56.6k |
Biggest calls
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +1.0 pts · filed 2025-11-05 | 15.0% |
| T. Rowe Price Investment Management, Inc. 13G · institution +5.0 pts · filed 2026-08-07 | 12.1% |
| BlackRock, Inc. 13G · institution +1.3 pts · filed 2026-07-28 | 6.4% |
| WELLINGTON MANAGEMENT GROUP LLP 13G · institution +1.1 pts · filed 2026-08-13 | 5.9% |
Fell to 5% or below in the last year: Sirenia Capital Management LP (3.1%, 2026-08-14), Point72 Asset Management, L.P. (1.2%, 2026-05-15), RA CAPITAL MANAGEMENT, L.P. (4.8%, 2026-05-15), Octagon Capital Advisors LP (3.6%, 2026-05-14), Fairmount Funds Management LLC (4.9%, 2025-11-25), Avidity Partners Management LP (4.9%, 2025-11-19), Deep Track Capital, LP (0.0%, 2025-11-14), BCLS Fund III Investments, LP (3.1%, 2025-11-14), Vestal Point Capital, LP (3.0%, 2025-11-14)
Insider purchases and sales in Q2 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 0 | — | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 2 | $1.5m | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 0 | — | — |
None reported in Q2 2024.
Holders, Q2 2024
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.01% of their portfolio | 4.4m $113.9m | Added +241.4k |
| Bain Capital Life Sciences Investors, LLC 8.56% of their portfolio | 3.0m $78.0m | Added +21.4k |
| Avidity Partners Management LP 3.21% of their portfolio | 2.9m $75.5m | Added +199.7k |
| Fairmount Funds Management LLC 8.08% of their portfolio | 2.8m $71.5m | Unchanged |
| RA CAPITAL MANAGEMENT, L.P. 0.80% of their portfolio | 2.3m $60.4m | Unchanged |
| Venrock Adviser, LLC 3.45% of their portfolio | 2.1m $54.2m | Unchanged |
| Octagon Capital Advisors LP 7.46% of their portfolio | 1.7m $45.2m | Added +366.0k |
| BlackRock Inc. 0.00% of their portfolio | 1.6m $41.5m | Added +1.6m |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.2m $32.2m | Added +707.4k |
| 5AM Venture Management, LLC 7.14% of their portfolio | 1.2m $31.9m | Reduced -9.1k |
| GREAT POINT PARTNERS LLC 3.76% of their portfolio | 757.9k $19.6m | Added +132.9k |
| JANUS HENDERSON GROUP PLC 0.01% of their portfolio | 675.7k $17.6m | Added +300.6k |
| RTW INVESTMENTS, LP 0.27% of their portfolio | 666.7k $17.3m | Unchanged |
| Vestal Point Capital, LP 1.16% of their portfolio | 600.0k $15.5m | Added +145.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 498.9k $12.9m | Added +424.5k |
| STATE STREET CORP 0.00% of their portfolio | 407.7k $10.6m | Added +387.3k |
| BRAIDWELL LP 0.30% of their portfolio | 366.9k $9.5m | New |
| TANG CAPITAL MANAGEMENT LLC 0.70% of their portfolio | 264.7k $6.9m | Unchanged |
| Woodline Partners LP 0.06% of their portfolio | 250.3k $6.5m | New |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 250.0k $6.5m | Reduced -48.0k |
| Alphabet Inc. 0.27% of their portfolio | 208.7k $5.4m | Unchanged |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 174.2k $4.5m | Reduced -177.9k |
| Atlas Venture Life Science Advisors, LLC 0.37% of their portfolio | 137.0k $3.5m | Reduced -50.0k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 108.2k $2.8m | Reduced -4.7k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 88.6k $2.3m | Reduced -17.1k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 86.8k $2.2m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 80.9k $2.1m | Added +72.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 68.6k $1.8m | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 54.7k $1.4m | Added +36.2k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 41.9k $1.1m | Reduced -128.3k |
| Point72 Asia (Singapore) Pte. Ltd. 0.21% of their portfolio | 39.5k $1.0m | Added +29.2k |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 37.1k $960.1k | Unchanged |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 32.1k $831.7k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 30.4k $787.6k | Added +8.5k |
| MORGAN STANLEY 0.00% of their portfolio | 27.0k $697.8k | Reduced -36.3k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 25.0k $647.3k | New |
| Alpine Global Management, LLC 0.11% of their portfolio | 23.4k $605.3k | New |
| ALPS ADVISORS INC 0.00% of their portfolio | 22.9k $593.0k | New |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 21.0k $542.9k | Reduced -3.1k |
| ArrowMark Colorado Holdings LLC 0.01% of their portfolio | 20.8k $538.0k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 20.5k $529.4k | Reduced -11.6k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 19.7k $509.5k | Reduced -2.0k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 18.4k $475.5k | Added +2.9k |
| Swiss National Bank 0.00% of their portfolio | 17.3k $447.7k | New |
| BESSEMER GROUP INC 0.00% of their portfolio | 14.8k $384.0k | Unchanged |
| Point72 (DIFC) Ltd 0.03% of their portfolio | 12.9k $333.9k | New |
| Corebridge Financial, Inc. 0.00% of their portfolio | 12.9k $332.9k | First filing |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 11.2k $290.0k | Reduced -56.6k |
| Invesco Ltd. 0.00% of their portfolio | 11.1k $288.2k | New |
| RBF Capital, LLC 0.02% of their portfolio | 10.8k $279.1k | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 10.5k $271.7k | Reduced -27.5k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 10.3k $267.1k | Added +10.1k |
| WINTON GROUP Ltd 0.02% of their portfolio | 10.2k $265.0k | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 10.2k $262.7k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 9.7k $251.3k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 9.7k $251.0k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 9.5k $245.1k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 9.1k $235.6k | New |
| BARCLAYS PLC 0.00% of their portfolio | 8.5k $220.0k | Reduced -5.9k |
| UBS Group AG 0.00% of their portfolio | 8.4k $217.6k | Reduced -6.1k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 8.1k $210.0k | New |
| Legal & General Group Plc 0.00% of their portfolio | 8.1k $207.3k | New |
| FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio | 6.3k $163.5k | Reduced -30.1k |
| CITIGROUP INC 0.00% of their portfolio | 6.1k $157.5k | Reduced -16.7k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 6.1k $157.5k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 4.3k $112.0k | New |
| VIRTUS ADVISERS, LLC 0.04% of their portfolio | 3.4k $86.9k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 2.3k $60.6k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 2.3k $60.0k | Added +2.2k |
| AMALGAMATED BANK 0.00% of their portfolio | 827 $21.0k | New |
| Quarry LP 0.00% of their portfolio | 66 $1.7k | New |
| ROTHSCHILD INVESTMENT LLC 0.00% of their portfolio | 5 $129 | New |
| INSTITUTIONAL & FAMILY ASSET MANAGEMENT, LLC 0.00% of their portfolio | 3 $78 | Unchanged |
| AlphaQuest LLC 0.00% of their portfolio | 1 $26 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |