Vault-13

DIANTHUS THERAPEUTICS INC DNTH

COM · Common Stock · CUSIP 252828108

Biotechnology company

75 institutional holders -2 vs Q1 2024
29,639,38229.6m shares reported held*
101.0% of all shares outstanding*
$767.1mreported value*
27 new 18 added 17 reduced 30 sold out net bought ≈ $92.3m (+3.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.9m this quarter). Holder counts are more reliable. Shares outstanding: 29.4m as of 2024-08-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $25.88. Options: 1 managers hold calls ($0 notional), 1 hold puts ($0).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

050100Q3 23: 31Q4 23: 40Q1 24: 77Q2 24: 7575Q3 23Q4 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 202331
Q4 202340
Q1 202477
Q2 202475

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 23: 20 bought or addedQ4 23: 7 cut or sold outQ4 23Q1 24: 63 bought or addedQ1 24: 10 cut or sold outQ1 24Q2 24: 45 bought or addedQ2 24: 47 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 2023207
Q1 20246310
Q2 20244547

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$1k$2k$3k$4kQ3 23 calls: $3.8kQ3 23 puts: $0Q3 23P/C 0.00Q4 23 calls: $0Q4 23 puts: $0Q4 23P/C —Q1 24 calls: $0Q1 24 puts: $0Q1 24P/C —Q2 24 calls: $0Q2 24 puts: $0Q2 24P/C —
Numbers
QuarterCallsPutsP/C
Q3 2023$3.8k$00.00
Q4 2023$0$0—
Q1 2024$0$0—
Q2 2024$0$0—

Biggest buyers

BlackRock Inc. Added +1,556,932+1.6m
VANGUARD GROUP INC Added +707,400+707.4k
GEODE CAPITAL MANAGEMENT, LLC Added +424,520+424.5k
STATE STREET CORP Added +387,308+387.3k
BRAIDWELL LP New +366,851+366.9k
Octagon Capital Advisors LP Added +366,000+366.0k
JANUS HENDERSON GROUP PLC Added +300,620+300.6k
Woodline Partners LP New +250,333+250.3k
FMR LLC Added +241,375+241.4k
Avidity Partners Management LP Added +199,677+199.7k

Biggest sellers

MILLENNIUM MANAGEMENT LLC Sold out -277,213-277.2k
Ally Bridge Group (NY) LLC Sold out -216,968-217.0k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Sold out -205,487-205.5k
Walleye Capital LLC Sold out -190,266-190.3k
Point72 Asset Management, L.P. Reduced -177,900-177.9k
GOLDMAN SACHS GROUP INC Reduced -128,348-128.3k
Soleus Capital Management, L.P. Sold out -100,000-100.0k
JANE STREET GROUP, LLC Sold out -82,051-82.1k
Hudson Bay Capital Management LP Sold out -80,000-80.0k
Qube Research & Technologies Ltd Reduced -56,641-56.6k

Biggest calls

Biggest puts

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
FMR LLC 13G · institution +1.0 pts · filed 2025-11-05 15.0% +1.0 pts 6.0m≈ $582.0m 2025-11-05
T. Rowe Price Investment Management, Inc. 13G · institution +5.0 pts · filed 2026-08-07 12.1% +5.0 pts 6.6m≈ $646.5m 2026-08-07
BlackRock, Inc. 13G · institution +1.3 pts · filed 2026-07-28 6.4% +1.3 pts 3.5m≈ $341.6m 2026-07-28
WELLINGTON MANAGEMENT GROUP LLP 13G · institution +1.1 pts · filed 2026-08-13 5.9% +1.1 pts 3.2m≈ $314.8m 2026-08-13

Fell to 5% or below in the last year: Sirenia Capital Management LP (3.1%, 2026-08-14), Point72 Asset Management, L.P. (1.2%, 2026-05-15), RA CAPITAL MANAGEMENT, L.P. (4.8%, 2026-05-15), Octagon Capital Advisors LP (3.6%, 2026-05-14), Fairmount Funds Management LLC (4.9%, 2025-11-25), Avidity Partners Management LP (4.9%, 2025-11-19), Deep Track Capital, LP (0.0%, 2025-11-14), BCLS Fund III Investments, LP (3.1%, 2025-11-14), Vestal Point Capital, LP (3.0%, 2025-11-14)

Insider purchases and sales in Q2 2024

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
202Q3 22: 0 buyingQ3 22: 0 sellingQ4 22: 0 buyingQ4 22: 0 sellingQ4 22Q1 23: 0 buyingQ1 23: 0 sellingQ2 23: 0 buyingQ2 23: 0 sellingQ2 23Q3 23: 2 buyingQ3 23: 0 sellingQ4 23: 0 buyingQ4 23: 0 sellingQ4 23Q1 24: 0 buyingQ1 24: 0 sellingQ2 24: 0 buyingQ2 24: 0 sellingQ2 24
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20220—0——
Q4 20220—0——
Q1 20230—0——
Q2 20230—0——
Q3 20232$1.5m0——
Q4 20230—0——
Q1 20240—0——
Q2 20240—0——

None reported in Q2 2024.

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FMR LLC 0.01% of their portfolio BOSTON, MA 4,402,4204.4m $113.9m $113.9m 0.01% Added +241.4k +241,375
2 Bain Capital Life Sciences Investors, LLC 8.56% of their portfolio Boston, MA 3,013,4233.0m $78.0m $78.0m 8.56% Added +21.4k +21,395
3 Avidity Partners Management LP 3.21% of their portfolio DALLAS, TX 2,917,2312.9m $75.5m $75.5m 3.21% Added +199.7k +199,677
4 Fairmount Funds Management LLC 8.08% of their portfolio WEST CONSHOHOCKEN, PA 2,762,8372.8m $71.5m $71.5m 8.08% Unchanged
5 RA CAPITAL MANAGEMENT, L.P. 0.80% of their portfolio BOSTON, MA 2,333,0002.3m $60.4m $60.4m 0.80% Unchanged
6 Venrock Adviser, LLC 3.45% of their portfolio NEW YORK, NY 2,094,3732.1m $54.2m $54.2m 3.45% Unchanged
7 Octagon Capital Advisors LP 7.46% of their portfolio NEW YORK, NY 1,746,6671.7m $45.2m $45.2m 7.46% Added +366.0k +366,000
8 BlackRock Inc. 0.00% of their portfolio New York, NY 1,603,5471.6m $41.5m $41.5m 0.00% Added +1.6m +1,556,932
9 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 1,245,2281.2m $32.2m $32.2m 0.00% Added +707.4k +707,400
10 5AM Venture Management, LLC 7.14% of their portfolio SAN FRANCISCO, CA 1,232,9651.2m $31.9m $31.9m 7.14% Reduced -9.1k -9,064
11 GREAT POINT PARTNERS LLC 3.76% of their portfolio Greenwich, CT 757,929757.9k $19.6m $19.6m 3.76% Added +132.9k +132,929
12 JANUS HENDERSON GROUP PLC 0.01% of their portfolio LONDON, X0 675,664675.7k $17.6m $17.6m 0.01% Added +300.6k +300,620
13 RTW INVESTMENTS, LP 0.27% of their portfolio NEW YORK, NY 666,667666.7k $17.3m $17.3m 0.27% Unchanged
14 Vestal Point Capital, LP 1.16% of their portfolio NEW YORK, NY 600,000600.0k $15.5m $15.5m 1.16% Added +145.0k +145,000
15 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 498,920498.9k $12.9m $12.9m 0.00% Added +424.5k +424,520
16 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 407,706407.7k $10.6m $10.6m 0.00% Added +387.3k +387,308
17 BRAIDWELL LP 0.30% of their portfolio STAMFORD, CT 366,851366.9k $9.5m $9.5m 0.30% New
18 TANG CAPITAL MANAGEMENT LLC 0.70% of their portfolio SAN DIEGO, CA 264,692264.7k $6.9m $6.9m 0.70% Unchanged
19 Woodline Partners LP 0.06% of their portfolio San Francisco, CA 250,333250.3k $6.5m $6.5m 0.06% New
20 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio Boston, MA 250,000250.0k $6.5m $6.5m 0.01% Reduced -48.0k -48,000
21 Alphabet Inc. 0.27% of their portfolio Mountain View, CA 208,697208.7k $5.4m $5.4m 0.27% Unchanged
22 Point72 Asset Management, L.P. 0.01% of their portfolio STAMFORD, CT 174,200174.2k $4.5m $4.5m 0.01% Reduced -177.9k -177,900
23 Atlas Venture Life Science Advisors, LLC 0.37% of their portfolio CAMBRIDGE, MA 136,979137.0k $3.5m $3.5m 0.37% Reduced -50.0k -50,000
24 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 108,199108.2k $2.8m $2.8m 0.00% Reduced -4.7k -4,731
25 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 88,60488.6k $2.3m $2.3m 0.00% Reduced -17.1k -17,100
26 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 86,77186.8k $2.2m $2.2m 0.00% New
27 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 80,93580.9k $2.1m $2.1m 0.00% Added +72.5k +72,509
28 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 68,56768.6k $1.8m $1.8m 0.00% New
29 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 54,68954.7k $1.4m $1.4m 0.00% Added +36.2k +36,198
30 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 41,86941.9k $1.1m $1.1m 0.00% Reduced -128.3k -128,348
31 Point72 Asia (Singapore) Pte. Ltd. 0.21% of their portfolio SINGAPORE, U0 39,50439.5k $1.0m $1.0m 0.21% Added +29.2k +29,159
32 PNC Financial Services Group, Inc. 0.00% of their portfolio Pittsburgh, PA 37,10037.1k $960.1k $960.1k 0.00% Unchanged
33 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 32,13832.1k $831.7k $831.7k 0.00% New
34 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 30,43230.4k $787.6k $787.6k 0.00% Added +8.5k +8,473
35 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 26,96127.0k $697.8k $697.8k 0.00% Reduced -36.3k -36,291
36 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 25,01025.0k $647.3k $647.3k 0.00% New
37 Alpine Global Management, LLC 0.11% of their portfolio NEW YORK, NY 23,38923.4k $605.3k $605.3k 0.11% New
38 ALPS ADVISORS INC 0.00% of their portfolio Denver, CO 22,91522.9k $593.0k $593.0k 0.00% New
39 Cubist Systematic Strategies, LLC 0.01% of their portfolio STAMFORD, CT 20,97621.0k $542.9k $542.9k 0.01% Reduced -3.1k -3,149
40 ArrowMark Colorado Holdings LLC 0.01% of their portfolio Denver, CO 20,78820.8k $538.0k $538.0k 0.01% Unchanged
41 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 20,45420.5k $529.4k $529.4k 0.00% Reduced -11.6k -11,582
42 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 19,72619.7k $509.5k $509.5k 0.00% Reduced -2.0k -2,002
43 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 18,37418.4k $475.5k $475.5k 0.00% Added +2.9k +2,879
44 Swiss National Bank 0.00% of their portfolio ZURICH, V8 17,30017.3k $447.7k $447.7k 0.00% New
45 BESSEMER GROUP INC 0.00% of their portfolio WOODBRIDGE, NJ 14,82914.8k $384.0k $384.0k 0.00% Unchanged
46 Point72 (DIFC) Ltd 0.03% of their portfolio DUBAI, C0 12,90012.9k $333.9k $333.9k 0.03% New
47 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 12,85912.9k $332.9k $332.9k 0.00% First filing
48 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 11,20511.2k $290.0k $290.0k 0.00% Reduced -56.6k -56,641
49 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 11,13511.1k $288.2k $288.2k 0.00% New
50 RBF Capital, LLC 0.02% of their portfolio RENO, NV 10,78410.8k $279.1k $279.1k 0.02% Unchanged
51 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 10,50010.5k $271.7k $271.7k 0.00% Reduced -27.5k -27,471
52 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 10,31910.3k $267.1k $267.1k 0.00% Added +10.1k +10,095
53 WINTON GROUP Ltd 0.02% of their portfolio LONDON, X0 10,23810.2k $265.0k $265.0k 0.02% New
54 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 10,15210.2k $262.7k $262.7k 0.00% New
55 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 9,7119.7k $251.3k $251.3k 0.00% New
56 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 9,7009.7k $251.0k $251.0k 0.00% New
57 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 9,4699.5k $245.1k $245.1k 0.00% New
58 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 9,1029.1k $235.6k $235.6k 0.00% New
59 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 8,4998.5k $220.0k $220.0k 0.00% Reduced -5.9k -5,904
60 UBS Group AG 0.00% of their portfolio ZURICH, V8 8,4098.4k $217.6k $217.6k 0.00% Reduced -6.1k -6,096
61 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 8,1168.1k $210.0k $210.0k 0.00% New
62 Legal & General Group Plc 0.00% of their portfolio London, X0 8,0548.1k $207.3k $207.3k 0.00% New
63 FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio NEW YORK, NY 6,3176.3k $163.5k $163.5k 0.00% Reduced -30.1k -30,050
64 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 6,0856.1k $157.5k $157.5k 0.00% Reduced -16.7k -16,651
65 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 6,0856.1k $157.5k $157.5k 0.00% New
66 SG Americas Securities, LLC 0.00% of their portfolio NEW YORK, NY 4,3334.3k $112.0k $112.0k 0.00% New
67 VIRTUS ADVISERS, LLC 0.04% of their portfolio HARTFORD, CT 3,3583.4k $86.9k $86.9k 0.04% New
68 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 2,3422.3k $60.6k $60.6k 0.00% New
69 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 2,3292.3k $60.0k $60.0k 0.00% Added +2.2k +2,248
70 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 827827 $21.0k $21.0k 0.00% New
71 Quarry LP 0.00% of their portfolio NEW YORK, NY 6666 $1.7k $1.7k 0.00% New
72 ROTHSCHILD INVESTMENT LLC 0.00% of their portfolio CHICAGO, IL 55 $129 $129 0.00% New
73 INSTITUTIONAL & FAMILY ASSET MANAGEMENT, LLC 0.00% of their portfolio Fort Collins, CO 33 $78 $78 0.00% Unchanged
74 AlphaQuest LLC 0.00% of their portfolio New York, NY 11 $26 $26 0.00% New
75 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged