DIAMEDICA THERAPEUTICS INC DMAC
COM NEW · Common Stock · CUSIP 25253X207
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersMinneapolis, MN
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.4k this quarter). Holder counts are more reliable. Shares outstanding: 52.1m as of 2025-11-10, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $7.96. Options: 4 managers hold calls ($313.6k notional), 4 hold puts ($222.1k).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 27 |
| Q4 2022 | 29 |
| Q1 2023 | 26 |
| Q2 2023 | 33 |
| Q3 2023 | 37 |
| Q4 2023 | 39 |
| Q1 2024 | 33 |
| Q2 2024 | 33 |
| Q3 2024 | 41 |
| Q4 2024 | 46 |
| Q1 2025 | 58 |
| Q2 2025 | 59 |
| Q3 2025 | 78 |
| Q4 2025 | 92 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 9 | 14 |
| Q2 2024 | 12 | 12 |
| Q3 2024 | 21 | 10 |
| Q4 2024 | 27 | 10 |
| Q1 2025 | 34 | 11 |
| Q2 2025 | 40 | 25 |
| Q3 2025 | 55 | 15 |
| Q4 2025 | 55 | 27 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $56.9k | $8.5k | 0.15 |
| Q2 2025 | $8.1k | $780 | 0.10 |
| Q3 2025 | $178.2k | $144.7k | 0.81 |
| Q4 2025 | $313.6k | $222.1k | 0.71 |
Biggest buyers
| BlackRock, Inc. | Added | +222.8k |
| STATE STREET CORP | Added | +151.2k |
| WELLINGTON MANAGEMENT GROUP LLP | New | +103.7k |
| MEMBERS WEALTH LLC | New | +101.4k |
| Informed Momentum Co LLC | New | +91.4k |
| FRED ALGER MANAGEMENT, LLC | New | +83.1k |
| MAGNOLIA CAPITAL ADVISORS LLC | Added | +67.4k |
| OSAIC HOLDINGS, INC. | Added | +64.7k |
| VANGUARD GROUP INC | Added | +58.5k |
| SEI INVESTMENTS CO | New | +55.7k |
Biggest sellers
| COOPERMAN LEON G | Reduced | -1.2m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -418.7k |
| Corient Private Wealth LP | Sold out | -140.0k |
| Corient IA LP | Sold out | -132.5k |
| CANTOR FITZGERALD, L. P. | Sold out | -100.0k |
| FIRST MANHATTAN CO. LLC. | Reduced | -100.0k |
| JANE STREET GROUP, LLC | Sold out | -57.5k |
| Qube Research & Technologies Ltd | Sold out | -39.5k |
| MORGAN STANLEY | Reduced | -32.0k |
| RAYMOND JAMES FINANCIAL INC | Reduced | -20.7k |
Biggest calls
| CITADEL ADVISORS LLC | New | $220.5k27.7k shares |
| GROUP ONE TRADING LLC | Added | $58.9k7.4k shares |
| SIMPLEX TRADING, LLC | Added | $31.8k4.0k shares |
| OSAIC HOLDINGS, INC. | New | $2.4k25 shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $102.7k12.9k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $84.4k10.6k shares |
| GROUP ONE TRADING LLC | Reduced | $23.1k2.9k shares |
| SIMPLEX TRADING, LLC | Unchanged | $11.9k1.5k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| TRILL AB 13G · passive investor +1.9 pts · filed 2026-02-06 | 16.9% |
| TomEnterprise AB 13G · passive investor filed 2025-07-30 | 16.3% |
| JACINTO RICHARD II 13G · passive investor filed 2025-11-07 | 9.6% |
| COOPERMAN LEON G 13G · passive investor +0.3 pts · filed 2026-02-17 | 6.6% |
Fell to 5% or below in the last year: DIALECTIC CAPITAL MANAGEMENT, LP (0.3%, 2026-02-17)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-11-25 | TRILL AB +1 10% owner · See Footnote | Bought | $626.5k73.1k shares |
| 2025-11-24 | TRILL AB +1 10% owner · See Footnote | Bought | $317.6k40.3k shares |
| 2025-11-21 | TRILL AB +1 10% owner · See Footnote | Bought | $1.5m208.9k shares |
| 2025-11-20 | TRILL AB +1 10% owner · See Footnote | Bought | $951.6k128.4k shares |
| 2025-11-19 | TRILL AB +1 10% owner · See Footnote | Bought | $1.7m240.4k shares |
| 2025-11-18 | TRILL AB +1 10% owner · See Footnote | Bought | $1.2m182.9k shares |
| 2025-11-17 | TRILL AB +1 10% owner · See Footnote | Bought | $1.2m187.4k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| COOPERMAN LEON G 0.53% of their portfolio | 2.0m $16.1m | Reduced -1.2m |
| BlackRock, Inc. 0.00% of their portfolio | 1.9m $15.1m | Added +222.8k |
| PARAGON ASSOCIATES & PARAGON ASSOCIATES II JOINT VENTURE 14.39% of their portfolio | 875.0k $7.0m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 768.6k $6.1m | Reduced -418.7k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 764.3k $6.1m | Added +52.4k |
| VANGUARD GROUP INC 0.00% of their portfolio | 723.1k $5.8m | Added +58.5k |
| STATE STREET CORP 0.00% of their portfolio | 627.8k $5.0m | Added +151.2k |
| MORGAN STANLEY 0.00% of their portfolio | 547.6k $4.4m | Reduced -32.0k |
| FIRST MANHATTAN CO. LLC. 0.01% of their portfolio | 405.0k $3.2m | Reduced -100.0k |
| Bleichroeder LP 0.54% of their portfolio | 382.3k $3.0m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 325.5k $2.6m | Reduced -14.1k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 247.0k $2.0m | Added +64.7k |
| LPL Financial LLC 0.00% of their portfolio | 197.2k $1.6m | Reduced -6.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 129.4k $1.0m | Added +52.1k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 121.0k $963.0k | Added +52.0k |
| Nuveen, LLC 0.00% of their portfolio | 111.0k $883.8k | Added +36.4k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 110.7k $881.5k | Added +41.4k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 103.7k $825.5k | New |
| MEMBERS WEALTH LLC 0.54% of their portfolio | 101.4k $864.3k | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 96.9k $771.2k | Added +4.5k |
| Kalehua Capital Management LLC 0.75% of their portfolio | 95.4k $759.1k | First filing |
| Informed Momentum Co LLC 0.08% of their portfolio | 91.4k $727.7k | New |
| FRED ALGER MANAGEMENT, LLC 0.00% of their portfolio | 83.1k $661.8k | New |
| MAGNOLIA CAPITAL ADVISORS LLC 0.13% of their portfolio | 77.4k $616.1k | Added +67.4k |
| Blue Trust, Inc. 0.01% of their portfolio | 69.1k $550.2k | Unchanged |
| Creative Planning 0.00% of their portfolio | 58.9k $468.5k | Added +20.1k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 56.9k $453.0k | Added +15.0k |
| SEI INVESTMENTS CO 0.00% of their portfolio | 55.7k $443.1k | New |
| BARCLAYS PLC 0.00% of their portfolio | 52.9k $421.2k | Added +7.5k |
| Meridian Wealth Management, LLC 0.01% of their portfolio | 50.6k $403.1k | Reduced -1.0k |
| Private Capital Management, LLC 0.04% of their portfolio | 50.0k $398.0k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 44.4k $353.3k | Added +16.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 40.6k $323.4k | Added +18.7k |
| CATALYST FINANCIAL PARTNERS LLC 0.03% of their portfolio | 38.5k $306.1k | Unchanged |
| World Investment Advisors 0.00% of their portfolio | 37.0k $294.3k | Added +2.6k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 35.8k $284.7k | Added +8.3k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 32.2k $256.3k | Reduced -6.9k |
| Trexquant Investment LP 0.00% of their portfolio | 31.0k $246.4k | New |
| XTX Topco Ltd 0.01% of their portfolio | 29.4k $234.1k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 26.8k $213.0k | Reduced -596 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 26.3k $209.5k | Added +14.1k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 24.4k $194.0k | Reduced -8.4k |
| Quadrature Capital Ltd 0.00% of their portfolio | 23.6k $187.6k | New |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 23.0k $160.9k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 19.7k $157.0k | Unchanged |
| MetLife Investment Management, LLC 0.00% of their portfolio | 19.1k $151.9k | Added +9.0k |
| Invesco Ltd. 0.00% of their portfolio | 18.6k $148.3k | Added +4.3k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 18.5k $146.9k | Added +4.5k |
| Stonebridge Capital Advisors LLC 0.01% of their portfolio | 17.5k $139.3k | Unchanged |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 17.1k $136.0k | New |
| Cornerstone Wealth Management, LLC 0.01% of their portfolio | 16.2k $129.3k | Unchanged |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 15.8k $125.8k | Reduced -20.7k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 15.8k $125.6k | Added +1.0k |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 15.6k $123.9k | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.01% of their portfolio | 13.9k $110.0k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 13.6k $107.9k | Reduced -12.0k |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 12.1k $96.6k | Added +10.1k |
| AXQ CAPITAL, LP 0.02% of their portfolio | 12.1k $96.1k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 11.8k $93.9k | Unchanged |
| Jump Financial, LLC 0.00% of their portfolio | 11.2k $89.5k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 11.2k $89.3k | New |
| Focus Partners Wealth 0.00% of their portfolio | 10.5k $83.7k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 10.2k $81.2k | Unchanged |
| Truvestments Capital LLC 0.01% of their portfolio | 9.8k $78.4k | Added +5.2k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 7.4k $59.2k | Added +8 |
| MassMutual Private Wealth & Trust, FSB 0.00% of their portfolio | 4.8k $38.4k | Unchanged |
| US BANCORP \DE\ 0.00% of their portfolio | 4.5k $36.0k | Added +187 |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 4.2k $33.7k | New |
| UBS Group AG 0.00% of their portfolio | 3.6k $28.7k | Reduced -9.7k |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 3.6k $28.7k | New |
| Legal & General Group Plc 0.00% of their portfolio | 3.5k $28.1k | Unchanged |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 2.7k $21.5k | Unchanged |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 2.7k $21.3k | Reduced -1.2k |
| STRS OHIO 0.00% of their portfolio | 2.3k $18.3k | Reduced -6.8k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 2.1k $16.6k | Added +442 |
| FMR LLC 0.00% of their portfolio | 1.8k $14.4k | Added +1.7k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 1.4k $11.1k | Added +1.0k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.4k $11.0k | Reduced -1.3k |
| TD Waterhouse Canada Inc. 0.00% of their portfolio | 1.1k $8.5k | Unchanged |
| AMALGAMATED BANK 0.00% of their portfolio | 1.1k $8.0k | Added +164 |
| Capital Analysts, LLC 0.00% of their portfolio | 1.1k $8.0k | New |
| CITIGROUP INC 0.00% of their portfolio | 864 $6.9k | Reduced -579 |
| Sterling Capital Management LLC 0.00% of their portfolio | 206 $1.6k | Added +129 |
| YANKCOM Partnership 0.00% of their portfolio | 200 $1.6k | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 156 $1.2k | New |
| Global Retirement Partners, LLC 0.00% of their portfolio | 130 $1.0k | New |
| GAMMA Investing LLC 0.00% of their portfolio | 102 $812 | Unchanged |
| Allworth Financial LP 0.00% of their portfolio | 101 $804 | Added +16 |
| Cornerstone Planning Group LLC 0.00% of their portfolio | 80 $675 | Added +74 |
| CWM, LLC 0.00% of their portfolio | 70 $1.0k | Reduced -16 |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 57 $454 | Reduced -393 |
| TORONTO DOMINION BANK 0.00% of their portfolio | 24 $191 | Unchanged |