Vault-13

CYMABAY THERAPEUTICS INC CBAY

COM · Common Stock · CUSIP 23257D103

201 institutional holders +11 vs Q3 2023
116,909,485116.9m shares reported held*
$2.8bnreported value*
34 new 79 added 60 reduced 33 sold out net bought ≈ $130.2m (+5.5m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($6.8m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $23.62. Options: 20 managers hold calls ($86.8m notional), 16 hold puts ($20.6m).

Trends to Q4 2023

Institutional holders

Managers reporting a position, each quarter

0100200300Q3 22: 100Q4 22: 118Q1 23: 141Q2 23: 152Q3 23: 190Q4 23: 201201Q3 22Q4 22Q1 23Q2 23Q3 23Q4 23
Numbers
QuarterHolders
Q3 2022100
Q4 2022118
Q1 2023141
Q2 2023152
Q3 2023190
Q4 2023201

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 53 bought or addedQ4 22: 35 cut or sold outQ4 22Q1 23: 85 bought or addedQ1 23: 55 cut or sold outQ1 23Q2 23: 87 bought or addedQ2 23: 73 cut or sold outQ2 23Q3 23: 119 bought or addedQ3 23: 77 cut or sold outQ3 23Q4 23: 113 bought or addedQ4 23: 93 cut or sold outQ4 23
Numbers
QuarterBought or addedCut or sold out
Q4 20225335
Q1 20238555
Q2 20238773
Q3 202311977
Q4 202311393

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$25m$50m$75m$100mQ1 23 calls: $6.5mQ1 23 puts: $3.4mQ1 23P/C 0.52Q2 23 calls: $3.8mQ2 23 puts: $225.5kQ2 23P/C 0.06Q3 23 calls: $35.0mQ3 23 puts: $32.9mQ3 23P/C 0.94Q4 23 calls: $86.8mQ4 23 puts: $20.6mQ4 23P/C 0.24
Numbers
QuarterCallsPutsP/C
Q1 2023$6.5m$3.4m0.52
Q2 2023$3.8m$225.5k0.06
Q3 2023$35.0m$32.9m0.94
Q4 2023$86.8m$20.6m0.24

Biggest buyers

LORD, ABBETT & CO. LLC New +2,642,438+2.6m
PRICE T ROWE ASSOCIATES INC /MD/ Added +2,561,460+2.6m
BlackRock Inc. Added +1,818,243+1.8m
FMR LLC Added +1,493,048+1.5m
Sofinnova Investments, Inc. New +1,411,769+1.4m
MORGAN STANLEY Added +1,406,419+1.4m
DEUTSCHE BANK AG\ Added +921,858+921.9k
Driehaus Capital Management LLC New +841,677+841.7k
Avoro Capital Advisors LLC Added +811,111+811.1k
MILLENNIUM MANAGEMENT LLC Added +777,926+777.9k

Biggest sellers

Cormorant Asset Management, LP Reduced -2,050,000-2.0m
Foresite Capital Management IV, LLC Sold out -1,787,094-1.8m
ADAGE CAPITAL PARTNERS GP, L.L.C. Reduced -1,497,000-1.5m
Nicholas Investment Partners, LP Reduced -1,405,507-1.4m
Balyasny Asset Management L.P. Sold out -1,024,139-1.0m
Lynx1 Capital Management LP Sold out -994,161-994.2k
Bain Capital Life Sciences Investors, LLC Sold out -913,969-914.0k
JANUS HENDERSON GROUP PLC Reduced -699,687-699.7k
Altium Capital Management LLC Reduced -689,000-689.0k
NOVO HOLDINGS A/S Reduced -666,521-666.5k

Biggest calls

Caption Management, LLC Added $19.8m839.9k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $18.5m783.9k shares
GROUP ONE TRADING LLC Added $11.1m470.5k shares
J. Goldman & Co LP New $9.4m396.6k shares
CITADEL ADVISORS LLC Added $6.2m261.2k shares
SIMPLEX TRADING, LLC Added $4.2m176.9k shares
JPMORGAN CHASE & CO Reduced $4.0m171.0k shares
D. E. Shaw & Co., Inc. New $3.5m150.0k shares
JANE STREET GROUP, LLC Reduced $2.4m102.7k shares
UBS Group AG New $2.4m100.0k shares

Biggest puts

JANE STREET GROUP, LLC Reduced $3.9m166.4k shares
GROUP ONE TRADING LLC Reduced $3.7m155.7k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $3.6m151.2k shares
J. Goldman & Co LP Reduced $2.9m124.5k shares
CITADEL ADVISORS LLC Reduced $1.7m70.5k shares
SIMPLEX TRADING, LLC Reduced $1.3m54.2k shares
Caption Management, LLC Reduced $1.0m44.3k shares
BARCLAYS PLC New $708.6k30.0k shares
CITIGROUP INC New $708.6k30.0k shares
Jefferies Financial Group Inc. New $420.4k17.8k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q4 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Avoro Capital Advisors LLC 3.63% of their portfolio NEW YORK, NY 11,111,11111.1m $262.4m $262.4m 3.63% Added +811.1k +811,111
2 BlackRock Inc. 0.01% of their portfolio New York, NY 9,610,2399.6m $227.0m $227.0m 0.01% Added +1.8m +1,818,243
3 RA CAPITAL MANAGEMENT, L.P. 2.56% of their portfolio BOSTON, MA 6,940,0006.9m $163.9m $163.9m 2.56% Unchanged
4 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 6,306,1496.3m $149.0m $149.0m 0.00% Added +558.6k +558,562
5 JANUS HENDERSON GROUP PLC 0.09% of their portfolio LONDON, X0 6,103,7976.1m $144.2m $144.2m 0.09% Reduced -699.7k -699,687
6 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 4,465,1614.5m $105.5m $105.5m 0.01% Added +2.6m +2,561,460
7 PERCEPTIVE ADVISORS LLC 2.12% of their portfolio NEW YORK, NY 4,024,4004.0m $95.1m $95.1m 2.12% Reduced -18.8k -18,791
8 JENNISON ASSOCIATES LLC 0.07% of their portfolio NEW YORK, NY 3,992,7114.0m $94.3m $94.3m 0.07% Added +437.4k +437,437
9 FRANKLIN RESOURCES INC 0.04% of their portfolio San Mateo, CA 3,267,9273.3m $77.2m $77.2m 0.04% Reduced -40.0k -39,988
10 FMR LLC 0.01% of their portfolio BOSTON, MA 3,061,9963.1m $72.3m $72.3m 0.01% Added +1.5m +1,493,048
11 Holocene Advisors, LP 0.28% of their portfolio New York, NY 2,993,9453.0m $70.7m $70.7m 0.28% Reduced -123.7k -123,740
12 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 2,797,9162.8m $66.1m $66.1m 0.00% Added +512.0k +511,972
13 Octagon Capital Advisors LP 10.10% of their portfolio NEW YORK, NY 2,673,7502.7m $63.2m $63.2m 10.10% Reduced -400.0k -400,000
14 LORD, ABBETT & CO. LLC 0.11% of their portfolio JERSEY CITY, NJ 2,642,4382.6m $62.4m $62.4m 0.11% New
15 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.13% of their portfolio Boston, MA 2,628,0002.6m $62.1m $62.1m 0.13% Reduced -1.5m -1,497,000
16 Point72 Asset Management, L.P. 0.18% of their portfolio STAMFORD, CT 2,573,7002.6m $60.8m $60.8m 0.18% Added +143.8k +143,776
17 GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio BOSTON, MA 2,380,1052.4m $56.2m $56.2m 0.01% Added +304.5k +304,549
18 FRED ALGER MANAGEMENT, LLC 0.25% of their portfolio NEW YORK, NY 1,967,8582.0m $46.5m $46.5m 0.25% Reduced -204.5k -204,451
19 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 1,913,8901.9m $45.2m $45.2m 0.00% Added +1.4m +1,406,419
20 Cormorant Asset Management, LP 2.04% of their portfolio BOSTON, MA 1,800,0001.8m $42.5m $42.5m 2.04% Reduced -2.0m -2,050,000
21 Vestal Point Capital, LP 4.07% of their portfolio NEW YORK, NY 1,625,0001.6m $38.4m $38.4m 4.07% First filing
22 First Turn Management, LLC 5.08% of their portfolio DEL MAR, CA 1,497,3311.5m $35.4m $35.4m 5.08% First filing
23 Sofinnova Investments, Inc. 1.87% of their portfolio Menlo Park, CA 1,411,7691.4m $33.3m $33.3m 1.87% New
24 DEUTSCHE BANK AG\ 0.02% of their portfolio FRANKFURT AM MAIN, 2M 1,377,9641.4m $32.5m $32.5m 0.02% Added +921.9k +921,858
25 DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio AUSTIN, TX 1,161,9641.2m $27.4m $27.4m 0.01% Unchanged
26 Affinity Asset Advisors, LLC 5.14% of their portfolio NEW YORK, NY 1,090,4411.1m $25.8m $25.8m 5.14% Reduced -38.9k -38,935
27 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 1,090,0871.1m $25.7m $25.7m 0.00% Added +82.6k +82,575
28 EMERALD ADVISERS, LLC 1.08% of their portfolio LEOLA, PA 1,068,6611.1m $25.2m $25.2m 1.08% Added +84.9k +84,886
29 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 921,330921.3k $21.8m $21.8m 0.02% Added +777.9k +777,926
30 NOVO HOLDINGS A/S 1.31% of their portfolio HELLERUP, G7 900,000900.0k $21.3m $21.3m 1.31% Reduced -666.5k -666,521
31 EMERALD MUTUAL FUND ADVISERS TRUST 1.10% of their portfolio LEOLA, PA 878,275878.3k $20.7m $20.7m 1.10% Added +68.5k +68,537
32 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.01% of their portfolio SAN FRANCISCO, CA 853,475853.5k $20.2m $20.2m 0.01% Added +54.9k +54,920
33 Driehaus Capital Management LLC 0.24% of their portfolio Chicago, IL 841,677841.7k $19.9m $19.9m 0.24% New
34 Nuveen Asset Management, LLC 0.01% of their portfolio CHICAGO, IL 751,508751.5k $17.8m $17.8m 0.01% Added +52.1k +52,116
35 Saturn V Capital Management LP 6.78% of their portfolio AUSTIN, TX 750,250750.2k $17.7m $17.7m 6.78% Reduced -374.2k -374,209
36 Assenagon Asset Management S.A. 0.05% of their portfolio SENNINGERBERG, N4 746,353746.4k $17.6m $17.6m 0.05% New
37 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 727,706727.7k $17.2m $17.2m 0.00% Reduced -214.1k -214,102
38 WESTFIELD CAPITAL MANAGEMENT CO LP 0.10% of their portfolio BOSTON, MA 700,056700.1k $16.5m $16.5m 0.10% New
39 VICTORY CAPITAL MANAGEMENT INC 0.02% of their portfolio San Antonio, TX 689,603689.6k $16.3m $16.3m 0.02% Reduced -347.8k -347,830
40 D. E. Shaw & Co., Inc. 0.02% of their portfolio New York, NY 636,897636.9k $15.0m $15.0m 0.02% Reduced -161.1k -161,112
41 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 630,735630.7k $14.9m $14.9m 0.00% Added +70.0k +69,974
42 MPM BIOIMPACT LLC 3.38% of their portfolio BOSTON, MA 611,181611.2k $14.4m $14.4m 3.38% Added +411 +411
43 Jefferies Financial Group Inc. 0.22% of their portfolio NEW YORK, NY 586,298586.3k $13.8m $13.8m 0.22% New
44 Woodline Partners LP 0.14% of their portfolio San Francisco, CA 532,002532.0k $12.6m $12.6m 0.14% Added +121.3k +121,287
45 Hood River Capital Management LLC 0.34% of their portfolio PALM BEACH GARDENS, FL 519,249519.2k $12.3m $12.3m 0.34% Added +6.8k +6,838
46 ACUTA CAPITAL PARTNERS, LLC 6.54% of their portfolio REDWOOD CITY, CA 492,155492.2k $11.6m $11.6m 6.54% Added +74.2k +74,155
47 Ally Bridge Group (NY) LLC 6.90% of their portfolio NEW YORK, NY 489,938489.9k $11.6m $11.6m 6.90% New
48 Nicholas Investment Partners, LP 1.20% of their portfolio RANCHO SANTA FE, CA 434,507434.5k $10.3m $10.3m 1.20% Reduced -1.4m -1,405,507
49 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 413,279413.3k $9.8m $9.8m 0.00% Added +37.7k +37,730
50 TANG CAPITAL MANAGEMENT LLC 0.76% of their portfolio SAN DIEGO, CA 350,000350.0k $8.3m $8.3m 0.76% Added +150.0k +150,000
51 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 349,739349.7k $8.3m $8.3m 0.00% Added +248.7k +248,739
52 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 330,234330.2k $7.8m $7.8m 0.01% Added +216.9k +216,927
53 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 319,714319.7k $7.6m $7.6m 0.00% Reduced -43.0k -42,973
54 Artal Group S.A. 0.24% of their portfolio LUXEMBOURG, N4 303,600303.6k $7.2m $7.2m 0.24% New
55 Moody Aldrich Partners LLC 1.11% of their portfolio MARBLEHEAD, MA 261,415261.4k $6.2m $6.2m 1.11% Reduced -64.6k -64,562
56 PRUDENTIAL FINANCIAL INC 0.01% of their portfolio NEWARK, NJ 233,921233.9k $5.5m $5.5m 0.01% Reduced -8.1k -8,056
57 SILVERARC CAPITAL MANAGEMENT, LLC 1.60% of their portfolio BOSTON, MA 218,975219.0k $5.2m $5.2m 1.60% Reduced -371.0k -371,025
58 Informed Momentum Co LLC 0.87% of their portfolio SOLANA BEACH, CA 207,152207.2k $4.9m $4.9m 0.87% Reduced -174.4k -174,412
59 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 202,782202.8k $4.8m $4.8m 0.00% New
60 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 194,968195.0k $4.6m $4.6m 0.01% Added +136.3k +136,320
61 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 190,332190.3k $4.5m $4.5m 0.00% Added +146.7k +146,694
62 STEMPOINT CAPITAL LP 1.24% of their portfolio NEW YORK, NY 182,258182.3k $4.3m $4.3m 1.24% First filing
63 ArrowMark Colorado Holdings LLC 0.05% of their portfolio Denver, CO 179,400179.4k $4.2m $4.2m 0.05% Unchanged
64 ExodusPoint Capital Management, LP 0.05% of their portfolio NEW YORK, NY 177,072177.1k $4.2m $4.2m 0.05% Added +163.4k +163,441
65 BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio PARIS, I0 169,082169.1k $4.0m $4.0m 0.01% Added +104.8k +104,776
66 J. Goldman & Co LP 0.22% of their portfolio NEW YORK, NY 165,937165.9k $3.9m $3.9m 0.22% Added +27.0k +26,988
67 HighVista Strategies LLC 1.37% of their portfolio BOSTON, MA 160,334160.3k $3.8m $3.8m 1.37% Reduced -20.0k -19,971
68 RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio NEW YORK, NY 159,950159.9k $3.8m $3.8m 0.01% Added +46.5k +46,500
69 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 157,556157.6k $3.7m $3.7m 0.00% Added +65.6k +65,600
70 Swiss National Bank 0.00% of their portfolio ZURICH, V8 155,400155.4k $3.7m $3.7m 0.00% Reduced -26.1k -26,100
71 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 150,752150.8k $3.6m $3.6m 0.00% Reduced -10.9k -10,913
72 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 150,169150.2k $3.5m $3.5m 0.00% Added +20.7k +20,665
73 TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio NEW YORK, NY 146,189146.2k $3.5m $3.5m 0.01% Reduced -100 -100
74 Atika Capital Management LLC 0.49% of their portfolio NEW YORK, NY 145,000145.0k $3.4m $3.4m 0.49% Added +29.0k +29,000
75 UBS Group AG 0.00% of their portfolio ZURICH, V8 138,241138.2k $3.3m $3.3m 0.00% Added +5.7k +5,741
76 Qube Research & Technologies Ltd 0.01% of their portfolio LONDON, X0 132,809132.8k $3.1m $3.1m 0.01% New
77 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 129,280129.3k $3.1m $3.1m 0.00% Added +29.8k +29,844
78 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 122,998123.0k $2.9m $2.9m 0.00% Added +83.3k +83,293
79 TWO SIGMA ADVISERS, LP 0.01% of their portfolio NEW YORK, NY 120,200120.2k $2.8m $2.8m 0.01% Reduced -547.8k -547,838
80 Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio ST. PETERSBURG, FL 113,883113.9k $2.7m $2.7m 0.00% Added +12.6k +12,554
81 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 111,550111.5k $2.6m $2.6m 0.00% Added +107.5k +107,451
82 Altium Capital Management LLC 1.81% of their portfolio NEW YORK, NY 111,000111.0k $2.6m $2.6m 1.81% Reduced -689.0k -689,000
83 ADVISORY RESEARCH INC 0.36% of their portfolio CHICAGO, IL 98,98599.0k $2.3m $2.3m 0.36% Reduced -5.6k -5,555
84 ClariVest Asset Management LLC 0.13% of their portfolio SAN DIEGO, CA 96,50596.5k $2.3m $2.3m 0.13% Added +24 +24
85 LPL Financial LLC 0.00% of their portfolio FORT MILL, SC 95,60195.6k $2.3m $2.3m 0.00% Reduced -27.8k -27,763
86 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 95,04395.0k $2.2m $2.2m 0.00% Added +30.6k +30,639
87 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 94,26094.3k $2.2m $2.2m 0.00% Added +22.8k +22,811
88 Squarepoint Ops LLC 0.01% of their portfolio NEW YORK, NY 93,13393.1k $2.2m $2.2m 0.01% Added +9.2k +9,232
89 Ghost Tree Capital, LLC 1.22% of their portfolio NEW YORK, NY 90,00090.0k $2.1m $2.1m 1.22% New
90 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 88,88288.9k $2.1m $2.1m 0.00% Reduced -5.7k -5,731
91 Legal & General Group Plc 0.00% of their portfolio London, X0 86,24486.2k $2.0m $2.0m 0.00% Added +3.1k +3,055
92 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 85,84285.8k $2.0m $2.0m 0.00% Added +9.7k +9,716
93 Hudson Bay Capital Management LP 0.02% of their portfolio STAMFORD, CT 85,00085.0k $2.0m $2.0m 0.02% Added +25.0k +25,000
94 ALGERT GLOBAL LLC 0.08% of their portfolio SAN FRANCISCO, CA 84,88384.9k $2.0m $2.0m 0.08% Reduced -8.0k -8,003
95 Lion Point Capital, LP 1.74% of their portfolio NEW YORK, NY 82,42582.4k $1.9m $1.9m 1.74% Unchanged
96 Allspring Global Investments Holdings, LLC 0.00% of their portfolio CHARLOTTE, NC 80,02980.0k $1.9m $1.9m 0.00% New
97 Hennion & Walsh Asset Management, Inc. 0.11% of their portfolio Parsippany, NJ 78,31178.3k $1.8m $1.8m 0.11% Added +5.5k +5,472
98 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 75,37475.4k $1.8m $1.8m 0.01% Added +2.9k +2,913
99 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 70,97271.0k $1.7m $1.7m 0.00% Reduced -13.4k -13,448
100 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 69,61569.6k $1.6m $1.6m 0.00% Reduced -2.3k -2,319