Vault-13

CYMABAY THERAPEUTICS INC CBAY

COM · Common Stock · CUSIP 23257D103

190 institutional holders +38 vs Q2 2023
107,950,654108.0m shares reported held*
$1.6bnreported value*
62 new 57 added 53 reduced 24 sold out net bought ≈ $230.2m (+15.4m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($5.4m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $14.91. Options: 15 managers hold calls ($35.0m notional), 19 hold puts ($32.9m).

Trends to Q3 2023

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 100Q4 22: 118Q1 23: 141Q2 23: 152Q3 23: 190190Q3 22Q4 22Q1 23Q2 23Q3 23
Numbers
QuarterHolders
Q3 2022100
Q4 2022118
Q1 2023141
Q2 2023152
Q3 2023190

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 53 bought or addedQ4 22: 35 cut or sold outQ4 22Q1 23: 85 bought or addedQ1 23: 55 cut or sold outQ1 23Q2 23: 87 bought or addedQ2 23: 73 cut or sold outQ2 23Q3 23: 119 bought or addedQ3 23: 77 cut or sold outQ3 23
Numbers
QuarterBought or addedCut or sold out
Q4 20225335
Q1 20238555
Q2 20238773
Q3 202311977

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$10m$20m$30m$40mQ4 22 calls: $2.8mQ4 22 puts: $1.5mQ4 22P/C 0.54Q1 23 calls: $6.5mQ1 23 puts: $3.4mQ1 23P/C 0.52Q2 23 calls: $3.8mQ2 23 puts: $225.5kQ2 23P/C 0.06Q3 23 calls: $35.0mQ3 23 puts: $32.9mQ3 23P/C 0.94
Numbers
QuarterCallsPutsP/C
Q4 2022$2.8m$1.5m0.54
Q1 2023$6.5m$3.4m0.52
Q2 2023$3.8m$225.5k0.06
Q3 2023$35.0m$32.9m0.94

Biggest buyers

RA CAPITAL MANAGEMENT, L.P. New +6,940,000+6.9m
Holocene Advisors, LP New +3,117,685+3.1m
Point72 Asset Management, L.P. New +2,429,924+2.4m
FRED ALGER MANAGEMENT, LLC New +2,172,309+2.2m
JENNISON ASSOCIATES LLC Added +1,883,742+1.9m
PRICE T ROWE ASSOCIATES INC /MD/ Added +1,809,280+1.8m
FMR LLC Added +1,557,462+1.6m
Nicholas Investment Partners, LP Added +1,143,067+1.1m
VICTORY CAPITAL MANAGEMENT INC Added +988,683+988.7k
EMERALD ADVISERS, LLC New +983,775+983.8k

Biggest sellers

Commodore Capital LP Sold out -2,025,000-2.0m
Bain Capital Life Sciences Investors, LLC Reduced -1,586,031-1.6m
Octagon Capital Advisors LP Reduced -1,497,168-1.5m
MILLENNIUM MANAGEMENT LLC Reduced -1,300,590-1.3m
JANUS HENDERSON GROUP PLC Reduced -943,103-943.1k
TWO SIGMA INVESTMENTS, LP Reduced -729,599-729.6k
Balyasny Asset Management L.P. Reduced -690,679-690.7k
MARSHALL WACE, LLP Reduced -623,324-623.3k
Opaleye Management Inc. Sold out -566,700-566.7k
Nantahala Capital Management, LLC Sold out -553,307-553.3k

Biggest calls

Caption Management, LLC New $8.0m536.1k shares
JANE STREET GROUP, LLC New $5.2m347.4k shares
Ghost Tree Capital, LLC New $3.5m237.9k shares
Ikarian Capital, LLC New $3.3m2.2k shares
JPMORGAN CHASE & CO New $3.0m200.3k shares
SILVERARC CAPITAL MANAGEMENT, LLC New $3.0m200.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $2.9m193.3k shares
CITADEL ADVISORS LLC Added $1.8m122.4k shares
BARCLAYS PLC New $1.2m83.8k shares
GROUP ONE TRADING LLC Reduced $1.2m78.6k shares

Biggest puts

Caption Management, LLC New $7.3m490.6k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $4.6m307.0k shares
JANE STREET GROUP, LLC New $3.5m231.8k shares
GROUP ONE TRADING LLC Added $3.2m215.5k shares
Schonfeld Strategic Advisors LLC New $3.1m210.0k shares
CITADEL ADVISORS LLC Added $2.6m174.0k shares
J. Goldman & Co LP New $2.0m135.0k shares
SIMPLEX TRADING, LLC Added $2.0m133.9k shares
Ikarian Capital, LLC New $1.2m816 shares
Octagon Capital Advisors LP New $894.6k60.0k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q3 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Avoro Capital Advisors LLC 2.40% of their portfolio NEW YORK, NY 10,300,00010.3m $153.6m $153.6m 2.40% Unchanged
2 BlackRock Inc. 0.00% of their portfolio New York, NY 7,791,9967.8m $116.2m $116.2m 0.00% Added +287.3k +287,326
3 RA CAPITAL MANAGEMENT, L.P. 2.04% of their portfolio BOSTON, MA 6,940,0006.9m $103.5m $103.5m 2.04% New
4 JANUS HENDERSON GROUP PLC 0.07% of their portfolio LONDON, X0 6,803,4846.8m $101.4m $101.4m 0.07% Reduced -943.1k -943,103
5 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 5,747,5875.7m $85.7m $85.7m 0.00% Added +598.7k +598,707
6 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.14% of their portfolio Boston, MA 4,125,0004.1m $61.5m $61.5m 0.14% Reduced -276.3k -276,292
7 PERCEPTIVE ADVISORS LLC 2.03% of their portfolio NEW YORK, NY 4,043,1914.0m $60.3m $60.3m 2.03% Added +309.9k +309,936
8 Cormorant Asset Management, LP 3.35% of their portfolio BOSTON, MA 3,850,0003.9m $57.4m $57.4m 3.35% Added +50.0k +50,000
9 JENNISON ASSOCIATES LLC 0.05% of their portfolio NEW YORK, NY 3,555,2743.6m $53.0m $53.0m 0.05% Added +1.9m +1,883,742
10 FRANKLIN RESOURCES INC 0.03% of their portfolio San Mateo, CA 3,307,9153.3m $49.3m $49.3m 0.03% Added +35.9k +35,907
11 Holocene Advisors, LP 0.21% of their portfolio New York, NY 3,117,6853.1m $46.5m $46.5m 0.21% New
12 Octagon Capital Advisors LP 8.07% of their portfolio NEW YORK, NY 3,073,7503.1m $45.8m $45.8m 8.07% Reduced -1.5m -1,497,168
13 Point72 Asset Management, L.P. 0.12% of their portfolio STAMFORD, CT 2,429,9242.4m $36.2m $36.2m 0.12% New
14 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 2,285,9442.3m $34.1m $34.1m 0.00% Reduced -22.5k -22,549
15 FRED ALGER MANAGEMENT, LLC 0.19% of their portfolio NEW YORK, NY 2,172,3092.2m $32.4m $32.4m 0.19% New
16 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 2,075,5562.1m $31.0m $31.0m 0.00% Added +220.1k +220,086
17 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 1,903,7011.9m $28.4m $28.4m 0.00% Added +1.8m +1,809,280
18 Nicholas Investment Partners, LP 2.05% of their portfolio RANCHO SANTA FE, CA 1,840,0141.8m $27.4m $27.4m 2.05% Added +1.1m +1,143,067
19 Foresite Capital Management IV, LLC 14.80% of their portfolio WEST HOLLYWOOD, CA 1,787,0941.8m $26.6m $26.6m 14.80% Unchanged
20 FMR LLC 0.00% of their portfolio BOSTON, MA 1,568,9481.6m $23.4m $23.4m 0.00% Added +1.6m +1,557,462
21 NOVO HOLDINGS A/S 1.73% of their portfolio HELLERUP, G7 1,566,5211.6m $23.4m $23.4m 1.73% Reduced -433.5k -433,479
22 DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio AUSTIN, TX 1,161,9641.2m $17.3m $17.3m 0.01% Reduced -5.4k -5,449
23 Affinity Asset Advisors, LLC 5.50% of their portfolio NEW YORK, NY 1,129,3761.1m $16.8m $16.8m 5.50% Added +79.3k +79,258
24 Saturn V Capital Management LP 7.02% of their portfolio AUSTIN, TX 1,124,4591.1m $16.8m $16.8m 7.02% Reduced -63.3k -63,342
25 VICTORY CAPITAL MANAGEMENT INC 0.02% of their portfolio San Antonio, TX 1,037,4331.0m $15.5m $15.5m 0.02% Added +988.7k +988,683
26 Balyasny Asset Management L.P. 0.04% of their portfolio Chicago, IL 1,024,1391.0m $15.3m $15.3m 0.04% Reduced -690.7k -690,679
27 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 1,007,5121.0m $15.0m $15.0m 0.00% Added +32.1k +32,113
28 Lynx1 Capital Management LP 9.80% of their portfolio DORADO, PR 994,161994.2k $14.8m $14.8m 9.80% Reduced -210.9k -210,889
29 EMERALD ADVISERS, LLC 0.71% of their portfolio LEOLA, PA 983,775983.8k $14.7m $14.7m 0.71% New
30 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 941,808941.8k $14.0m $14.0m 0.00% Added +19.8k +19,789
31 Bain Capital Life Sciences Investors, LLC 1.52% of their portfolio Boston, MA 913,969914.0k $13.6m $13.6m 1.52% Reduced -1.6m -1,586,031
32 EMERALD MUTUAL FUND ADVISERS TRUST 0.73% of their portfolio LEOLA, PA 809,738809.7k $12.1m $12.1m 0.73% New
33 Altium Capital Management LLC 6.90% of their portfolio NEW YORK, NY 800,000800.0k $11.9m $11.9m 6.90% Added +131.3k +131,298
34 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 798,555798.6k $11.9m $11.9m 0.00% Added +533.8k +533,821
35 D. E. Shaw & Co., Inc. 0.02% of their portfolio New York, NY 798,009798.0k $11.9m $11.9m 0.02% Added +105.6k +105,608
36 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 699,392699.4k $10.4m $10.4m 0.00% Added +400.5k +400,517
37 TWO SIGMA ADVISERS, LP 0.03% of their portfolio NEW YORK, NY 668,038668.0k $10.0m $10.0m 0.03% Reduced -488.4k -488,400
38 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.01% of their portfolio BOSTON, MA 628,303628.3k $9.4m $9.4m 0.01% New
39 MPM BIOIMPACT LLC 2.43% of their portfolio BOSTON, MA 610,770610.8k $9.1m $9.1m 2.43% New
40 SILVERARC CAPITAL MANAGEMENT, LLC 3.28% of their portfolio BOSTON, MA 590,000590.0k $8.8m $8.8m 3.28% Added +430.0k +430,000
41 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 560,761560.8k $8.4m $8.4m 0.00% Reduced -12.4k -12,384
42 Hood River Capital Management LLC 0.25% of their portfolio PALM BEACH GARDENS, FL 512,411512.4k $7.6m $7.6m 0.25% New
43 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 507,471507.5k $7.6m $7.6m 0.00% Reduced -316.2k -316,228
44 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 456,106456.1k $6.8m $6.8m 0.00% Reduced -369.9k -369,851
45 ACUTA CAPITAL PARTNERS, LLC 4.53% of their portfolio REDWOOD CITY, CA 418,000418.0k $6.2m $6.2m 4.53% Reduced -12.0k -12,000
46 Woodline Partners LP 0.07% of their portfolio San Francisco, CA 410,715410.7k $6.1m $6.1m 0.07% Added +125.0k +124,998
47 Informed Momentum Co LLC 1.10% of their portfolio SOLANA BEACH, CA 381,564381.6k $5.7m $5.7m 1.10% Added +8.9k +8,940
48 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 375,549375.5k $5.6m $5.6m 0.00% Reduced -1.9k -1,938
49 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 362,687362.7k $5.4m $5.4m 0.00% Reduced -60.8k -60,774
50 Moody Aldrich Partners LLC 0.92% of their portfolio MARBLEHEAD, MA 325,977326.0k $4.9m $4.9m 0.92% Added +210.6k +210,637
51 Schonfeld Strategic Advisors LLC 0.03% of their portfolio NEW YORK, NY 244,620244.6k $3.6m $3.6m 0.03% Added +173.9k +173,938
52 PRUDENTIAL FINANCIAL INC 0.01% of their portfolio NEWARK, NJ 241,977242.0k $3.8m $3.8m 0.01% Added +867 +867
53 Trexquant Investment LP 0.08% of their portfolio STAMFORD, CT 219,755219.8k $3.3m $3.3m 0.08% Added +163.3k +163,278
54 TANG CAPITAL MANAGEMENT LLC 0.42% of their portfolio SAN DIEGO, CA 200,000200.0k $3.0m $3.0m 0.42% New
55 Swiss National Bank 0.00% of their portfolio ZURICH, V8 181,500181.5k $2.7m $2.7m 0.00% Added +22.6k +22,600
56 HighVista Strategies LLC 1.24% of their portfolio BOSTON, MA 180,305180.3k $2.7m $2.7m 1.24% Reduced -158.5k -158,537
57 ArrowMark Colorado Holdings LLC 0.03% of their portfolio Denver, CO 179,400179.4k $2.7m $2.7m 0.03% New
58 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 161,665161.7k $2.4m $2.4m 0.00% Reduced -10.4k -10,392
59 MARSHALL WACE, LLP 0.01% of their portfolio LONDON, X0 158,411158.4k $2.4m $2.4m 0.01% Reduced -623.3k -623,324
60 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 156,053156.1k $2.3m $2.3m 0.00% Added +37.1k +37,087
61 TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio NEW YORK, NY 146,289146.3k $2.2m $2.2m 0.01% Reduced -729.6k -729,599
62 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 143,404143.4k $2.1m $2.1m 0.00% Reduced -1.3m -1,300,590
63 J. Goldman & Co LP 0.10% of their portfolio NEW YORK, NY 138,949138.9k $2.1m $2.1m 0.10% New
64 UBS Group AG 0.00% of their portfolio ZURICH, V8 132,500132.5k $2.0m $2.0m 0.00% Added +78.6k +78,633
65 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 129,504129.5k $1.9m $1.9m 0.00% Added +3.5k +3,478
66 LPL Financial LLC 0.00% of their portfolio FORT MILL, SC 123,364123.4k $1.8m $1.8m 0.00% Reduced -8.2k -8,206
67 Atika Capital Management LLC 0.25% of their portfolio NEW YORK, NY 116,000116.0k $1.7m $1.7m 0.25% New
68 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 113,450113.5k $1.7m $1.7m 0.00% Reduced -156.6k -156,570
69 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 113,307113.3k $1.7m $1.7m 0.00% Reduced -336.2k -336,155
70 ADVISORY RESEARCH INC 0.22% of their portfolio CHICAGO, IL 104,540104.5k $1.6m $1.6m 0.22% Reduced -17.7k -17,693
71 Ikarian Capital, LLC 0.58% of their portfolio DALLAS, TX 104,300104.3k $1.6m $1.6m 0.58% New
72 Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio ST. PETERSBURG, FL 101,329101.3k $1.5m $1.5m 0.00% Added +3.4k +3,434
73 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 101,000101.0k $1.5m $1.5m 0.00% Unchanged
74 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 99,43699.4k $1.5m $1.5m 0.00% Added +61.8k +61,806
75 ClariVest Asset Management LLC 0.08% of their portfolio SAN DIEGO, CA 96,48196.5k $1.4m $1.4m 0.08% Reduced -63.6k -63,600
76 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 94,61394.6k $1.4m $1.4m 0.00% Reduced -2.2k -2,212
77 ALGERT GLOBAL LLC 0.07% of their portfolio SAN FRANCISCO, CA 92,88692.9k $1.4m $1.4m 0.07% New
78 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 91,95692.0k $1.4m $1.4m 0.00% New
79 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 84,42084.4k $1.3m $1.3m 0.00% Added +28.5k +28,545
80 Squarepoint Ops LLC 0.01% of their portfolio NEW YORK, NY 83,90183.9k $1.3m $1.3m 0.01% Reduced -18.2k -18,232
81 Legal & General Group Plc 0.00% of their portfolio London, X0 83,18983.2k $1.2m $1.2m 0.00% Added +6.2k +6,232
82 Lion Point Capital, LP 1.12% of their portfolio NEW YORK, NY 82,42582.4k $1.2m $1.2m 1.12% Reduced -17.0k -17,000
83 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 76,12676.1k $1.1m $1.1m 0.00% Added +7.1k +7,091
84 Monashee Investment Management LLC 0.47% of their portfolio Boston, MA 75,00075.0k $1.1m $1.1m 0.47% New
85 Hennion & Walsh Asset Management, Inc. 0.07% of their portfolio Parsippany, NJ 72,83972.8k $1.1m $1.1m 0.07% Added +34.4k +34,403
86 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 72,46172.5k $1.1m $1.1m 0.01% Added +783 +783
87 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 71,93471.9k $1.1m $1.1m 0.00% Reduced -9.4k -9,381
88 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 71,44971.4k $1.1m $1.1m 0.00% Added +65.4k +65,361
89 Bayesian Capital Management, LP 0.11% of their portfolio Brooklyn, NY 67,40067.4k $1.0m $1.0m 0.11% Added +28.5k +28,500
90 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 64,40464.4k $960.3k $960.3k 0.00% Added +18.4k +18,381
91 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 64,30664.3k $958.8k $958.8k 0.00% Added +38.7k +38,727
92 Jump Financial, LLC 0.04% of their portfolio Chicago, IL 63,68463.7k $949.5k $949.5k 0.04% New
93 ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio Berwyn, PA 63,42863.4k $945.7k $945.7k 0.00% New
94 Cubist Systematic Strategies, LLC 0.01% of their portfolio STAMFORD, CT 62,51662.5k $932.1k $932.1k 0.01% Added +10.8k +10,771
95 Hudson Bay Capital Management LP 0.00% of their portfolio STAMFORD, CT 60,00060.0k $894.6k $894.6k 0.00% New
96 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 58,64858.6k $874.4k $874.4k 0.00% Added +32.0k +32,010
97 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 58,62858.6k $874.1k $874.1k 0.00% Reduced -123.1k -123,091
98 SIMPLEX TRADING, LLC 0.03% of their portfolio CHICAGO, IL 55,62955.6k $829.0k $829.0k 0.03% New
99 Engineers Gate Manager LP 0.03% of their portfolio NEW YORK, NY 53,98254.0k $804.9k $804.9k 0.03% New
100 MetLife Investment Management, LLC 0.01% of their portfolio Whippany, NJ 51,80251.8k $772.4k $772.4k 0.01% Unchanged