Vault-13

CYMABAY THERAPEUTICS INC CBAY

COM · Common Stock · CUSIP 23257D103

152 institutional holders +11 vs Q1 2023
92,587,17692.6m shares reported held*
$1.0bnreported value*
45 new 42 added 40 reduced 33 sold out net bought ≈ $41.4m (+3.8m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($3.0m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $10.95. Options: 6 managers hold calls ($3.8m notional), 5 hold puts ($225.5k).

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 100Q4 22: 118Q1 23: 141Q2 23: 152152Q3 22Q4 22Q1 23Q2 23
Numbers
QuarterHolders
Q3 2022100
Q4 2022118
Q1 2023141
Q2 2023152

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 53 bought or addedQ4 22: 35 cut or sold outQ4 22Q1 23: 85 bought or addedQ1 23: 55 cut or sold outQ1 23Q2 23: 87 bought or addedQ2 23: 73 cut or sold outQ2 23
Numbers
QuarterBought or addedCut or sold out
Q4 20225335
Q1 20238555
Q2 20238773

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$2m$4m$6m$8mQ3 22 calls: $865.0kQ3 22 puts: $520.0kQ3 22P/C 0.60Q4 22 calls: $2.8mQ4 22 puts: $1.5mQ4 22P/C 0.54Q1 23 calls: $6.5mQ1 23 puts: $3.4mQ1 23P/C 0.52Q2 23 calls: $3.8mQ2 23 puts: $225.5kQ2 23P/C 0.06
Numbers
QuarterCallsPutsP/C
Q3 2022$865.0k$520.0k0.60
Q4 2022$2.8m$1.5m0.54
Q1 2023$6.5m$3.4m0.52
Q2 2023$3.8m$225.5k0.06

Biggest buyers

BlackRock Inc. Added +4,854,593+4.9m
Cormorant Asset Management, LP Added +2,528,571+2.5m
NOVO HOLDINGS A/S New +2,000,000+2.0m
STATE STREET CORP Added +1,639,457+1.6m
JENNISON ASSOCIATES LLC Added +1,047,869+1.0m
GEODE CAPITAL MANAGEMENT, LLC Added +950,512+950.5k
NORTHERN TRUST CORP Added +765,922+765.9k
VANGUARD GROUP INC Added +699,272+699.3k
Nicholas Investment Partners, LP New +696,947+696.9k
Opaleye Management Inc. New +566,700+566.7k

Biggest sellers

TCG Crossover Management, LLC Sold out -3,048,257-3.0m
Laurion Capital Management LP Reduced -1,707,747-1.7m
MILLENNIUM MANAGEMENT LLC Reduced -1,505,062-1.5m
Nantahala Capital Management, LLC Reduced -1,236,796-1.2m
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced -1,065,457-1.1m
JANE STREET GROUP, LLC Reduced -544,861-544.9k
TWO SIGMA INVESTMENTS, LP Reduced -543,652-543.7k
GREAT POINT PARTNERS LLC Sold out -507,500-507.5k
683 Capital Management, LLC Sold out -500,000-500.0k
Hudson Bay Capital Management LP Sold out -480,172-480.2k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $1.2m113.6k shares
SIMPLEX TRADING, LLC Reduced $1.1m99.7k shares
GROUP ONE TRADING LLC Reduced $878.2k80.2k shares
CITADEL ADVISORS LLC Added $579.3k52.9k shares
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) Not comparable $56.2k75.0k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $158.8k14.5k shares
CITADEL ADVISORS LLC Reduced $50.4k4.6k shares
GROUP ONE TRADING LLC Reduced $15.3k1.4k shares
SIMPLEX TRADING, LLC Reduced $1.0k100 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Avoro Capital Advisors LLC 1.53% of their portfolio NEW YORK, NY 10,300,00010.3m $112.8m $112.8m 1.53% Unchanged
2 JANUS HENDERSON GROUP PLC 0.05% of their portfolio LONDON, X0 7,746,5877.7m $84.8m $84.8m 0.05% Added +250.5k +250,538
3 BlackRock Inc. 0.00% of their portfolio New York, NY 7,504,6707.5m $82.2m $82.2m 0.00% Added +4.9m +4,854,593
4 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 5,148,8805.1m $56.4m $56.4m 0.00% Added +699.3k +699,272
5 Octagon Capital Advisors LP 6.98% of their portfolio NEW YORK, NY 4,570,9184.6m $50.1m $50.1m 6.98% Unchanged
6 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.10% of their portfolio Boston, MA 4,401,2924.4m $48.2m $48.2m 0.10% Added +1.9k +1,892
7 Cormorant Asset Management, LP 2.37% of their portfolio BOSTON, MA 3,800,0003.8m $41.6m $41.6m 2.37% Added +2.5m +2,528,571
8 PERCEPTIVE ADVISORS LLC 1.19% of their portfolio NEW YORK, NY 3,733,2553.7m $40.9m $40.9m 1.19% Reduced -170.0k -170,000
9 FRANKLIN RESOURCES INC 0.02% of their portfolio San Mateo, CA 3,272,0083.3m $35.8m $35.8m 0.02% Added +47.1k +47,146
10 Bain Capital Life Sciences Investors, LLC 2.82% of their portfolio Boston, MA 2,500,0002.5m $27.4m $27.4m 2.82% Unchanged
11 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 2,308,4932.3m $25.3m $25.3m 0.00% Added +1.6m +1,639,457
12 Commodore Capital LP 2.49% of their portfolio NEW YORK, NY 2,025,0002.0m $22.2m $22.2m 2.49% Unchanged
13 NOVO HOLDINGS A/S 1.69% of their portfolio HELLERUP, G7 2,000,0002.0m $21.9m $21.9m 1.69% New
14 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,855,4701.9m $20.3m $20.3m 0.00% Added +950.5k +950,512
15 Foresite Capital Management IV, LLC 9.62% of their portfolio WEST HOLLYWOOD, CA 1,787,0941.8m $19.6m $19.6m 9.62% Unchanged
16 Balyasny Asset Management L.P. 0.05% of their portfolio Chicago, IL 1,714,8181.7m $18.8m $18.8m 0.05% Reduced -242.2k -242,250
17 JENNISON ASSOCIATES LLC 0.02% of their portfolio NEW YORK, NY 1,671,5321.7m $18.3m $18.3m 0.02% Added +1.0m +1,047,869
18 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 1,443,9941.4m $15.8m $15.8m 0.02% Reduced -1.5m -1,505,062
19 Lynx1 Capital Management LP 8.65% of their portfolio DORADO, PR 1,205,0501.2m $13.2m $13.2m 8.65% Reduced -164.9k -164,877
20 Saturn V Capital Management LP 7.21% of their portfolio AUSTIN, TX 1,187,8011.2m $13.0m $13.0m 7.21% Reduced -441.7k -441,663
21 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 1,167,4131.2m $12.8m $12.8m 0.00% Reduced -15.8k -15,823
22 TWO SIGMA ADVISERS, LP 0.03% of their portfolio NEW YORK, NY 1,156,4381.2m $12.7m $12.7m 0.03% Reduced -258.4k -258,400
23 Affinity Asset Advisors, LLC 4.53% of their portfolio NEW YORK, NY 1,050,1181.1m $11.5m $11.5m 4.53% Reduced -33.0k -33,000
24 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 975,399975.4k $10.7m $10.7m 0.00% Added +765.9k +765,922
25 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 922,019922.0k $10.1m $10.1m 0.00% Reduced -32.6k -32,608
26 TWO SIGMA INVESTMENTS, LP 0.03% of their portfolio NEW YORK, NY 875,888875.9k $9.6m $9.6m 0.03% Reduced -543.7k -543,652
27 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 825,957826.0k $9.0m $9.0m 0.00% Added +430.9k +430,868
28 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 823,699823.7k $9.0m $9.0m 0.00% Reduced -168.7k -168,682
29 MARSHALL WACE, LLP 0.02% of their portfolio LONDON, X0 781,735781.7k $8.6m $8.6m 0.02% Added +538.6k +538,554
30 Nicholas Investment Partners, LP 0.52% of their portfolio RANCHO SANTA FE, CA 696,947696.9k $7.6m $7.6m 0.52% New
31 D. E. Shaw & Co., Inc. 0.01% of their portfolio New York, NY 692,401692.4k $7.6m $7.6m 0.01% Added +143.4k +143,357
32 Altium Capital Management LLC 5.73% of their portfolio NEW YORK, NY 668,702668.7k $7.3m $7.3m 5.73% Added +48.7k +48,702
33 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 573,145573.1k $6.3m $6.3m 0.00% Reduced -200.2k -200,201
34 Opaleye Management Inc. 1.48% of their portfolio BOSTON, MA 566,700566.7k $6.2m $6.2m 1.48% New
35 Nantahala Capital Management, LLC 0.74% of their portfolio NEW CANAAN, CT 553,307553.3k $6.1m $6.1m 0.74% Reduced -1.2m -1,236,796
36 Versant Venture Management, LLC 7.06% of their portfolio San Francisco, CA 543,753543.8k $6.0m $6.0m 7.06% Unchanged
37 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 449,462449.5k $4.9m $4.9m 0.01% Added +123.6k +123,576
38 ACUTA CAPITAL PARTNERS, LLC 3.19% of their portfolio REDWOOD CITY, CA 430,000430.0k $4.7m $4.7m 3.19% Reduced -448.5k -448,500
39 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 423,461423.5k $4.6m $4.6m 0.00% Reduced -118.9k -118,946
40 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio JUPITER, FL 382,472382.5k $4.2m $4.2m 0.02% Reduced -261.3k -261,340
41 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 377,487377.5k $4.1m $4.1m 0.00% Added +337.5k +337,506
42 Soleus Capital Management, L.P. 0.45% of their portfolio GREENWICH, CT 373,000373.0k $4.1m $4.1m 0.45% New
43 Informed Momentum Co LLC 0.76% of their portfolio SOLANA BEACH, CA 372,624372.6k $4.1m $4.1m 0.76% Added +56.0k +56,030
44 HighVista Strategies LLC 1.70% of their portfolio BOSTON, MA 338,842338.8k $3.7m $3.7m 1.70% Reduced -8.9k -8,944
45 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 298,875298.9k $3.3m $3.3m 0.00% New
46 Woodline Partners LP 0.04% of their portfolio San Francisco, CA 285,717285.7k $3.1m $3.1m 0.04% Unchanged
47 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 270,020270.0k $3.0m $3.0m 0.00% Reduced -211.5k -211,480
48 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 264,734264.7k $2.9m $2.9m 0.00% Added +226.3k +226,254
49 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 241,110241.1k $2.6m $2.6m 0.00% New
50 Walleye Capital LLC 0.05% of their portfolio NEW YORK, NY 234,643234.6k $2.6m $2.6m 0.05% New
51 Laurion Capital Management LP 0.10% of their portfolio NEW YORK, NY 214,356214.4k $2.3m $2.3m 0.10% Reduced -1.7m -1,707,747
52 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 181,719181.7k $2.0m $2.0m 0.00% Reduced -344.0k -343,974
53 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 172,057172.1k $1.9m $1.9m 0.00% Added +106.3k +106,311
54 Artia Global Partners LP 0.64% of their portfolio MIAMI, FL 169,277169.3k $1.9m $1.9m 0.64% Unchanged
55 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.01% of their portfolio TORONTO, A6 162,400162.4k $1.8m $1.8m 0.01% Reduced -224.2k -224,200
56 ClariVest Asset Management LLC 0.09% of their portfolio SAN DIEGO, CA 160,081160.1k $1.8m $1.8m 0.09% Added +28.9k +28,940
57 SILVERARC CAPITAL MANAGEMENT, LLC 0.59% of their portfolio BOSTON, MA 160,000160.0k $1.8m $1.8m 0.59% New
58 Swiss National Bank 0.00% of their portfolio ZURICH, V8 158,900158.9k $1.7m $1.7m 0.00% Reduced -23.8k -23,800
59 LPL Financial LLC 0.00% of their portfolio FORT MILL, SC 131,570131.6k $1.4m $1.4m 0.00% Added +12.7k +12,741
60 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 126,026126.0k $1.4m $1.4m 0.00% New
61 ADVISORY RESEARCH INC 0.17% of their portfolio CHICAGO, IL 122,233122.2k $1.3m $1.3m 0.17% New
62 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 118,966119.0k $1.3m $1.3m 0.00% Reduced -1.1m -1,065,457
63 Campbell & CO Investment Adviser LLC 0.23% of their portfolio BALTIMORE, MD 116,439116.4k $1.3m $1.3m 0.23% Added +37.0k +36,960
64 Moody Aldrich Partners LLC 0.25% of their portfolio MARBLEHEAD, MA 115,340115.3k $1.3m $1.3m 0.25% New
65 Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio VANCOUVER, A1 104,271104.3k $1.1m $1.1m 0.01% Reduced -236.4k -236,367
66 Squarepoint Ops LLC 0.01% of their portfolio NEW YORK, NY 102,133102.1k $1.1m $1.1m 0.01% Added +8.3k +8,251
67 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 101,000101.0k $1.1m $1.1m 0.00% New
68 Lion Point Capital, LP 0.81% of their portfolio NEW YORK, NY 99,42599.4k $1.1m $1.1m 0.81% Unchanged
69 Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio ST. PETERSBURG, FL 97,89597.9k $1.1m $1.1m 0.00% Added +37.7k +37,736
70 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 96,82596.8k $1.1m $1.1m 0.00% Added +22.4k +22,434
71 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 94,42194.4k $1.0m $1.0m 0.00% Added +21.8k +21,810
72 OCCUDO QUANTITATIVE STRATEGIES LP 0.10% of their portfolio FORT LAUDERDALE, FL 85,81285.8k $939.6k $939.6k 0.10% New
73 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 81,31581.3k $890.4k $890.4k 0.00% Added +3.2k +3,191
74 Legal & General Group Plc 0.00% of their portfolio London, X0 76,95777.0k $843.2k $843.2k 0.00% Added +40.4k +40,372
75 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 71,67871.7k $784.9k $784.9k 0.01% Added +9.3k +9,298
76 Schonfeld Strategic Advisors LLC 0.01% of their portfolio NEW YORK, NY 70,68270.7k $774.0k $774.0k 0.01% New
77 Tri Locum Partners LP 0.29% of their portfolio NEW YORK, NY 70,58870.6k $772.9k $772.9k 0.29% New
78 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 69,03569.0k $602.0k $602.0k 0.00% Unchanged
79 Graham Capital Management, L.P. 0.03% of their portfolio ROWAYTON, CT 68,57968.6k $750.9k $750.9k 0.03% Reduced -76.4k -76,395
80 Trexquant Investment LP 0.02% of their portfolio STAMFORD, CT 56,47756.5k $618.4k $618.4k 0.02% Reduced -7.4k -7,409
81 SEI INVESTMENTS CO 0.00% of their portfolio OAKS, PA 55,87555.9k $611.8k $611.8k 0.00% New
82 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 54,24154.2k $593.9k $593.9k 0.00% Added +27.3k +27,265
83 UBS Group AG 0.00% of their portfolio ZURICH, V8 53,86753.9k $589.8k $589.8k 0.00% Reduced -15.9k -15,933
84 Baker Avenue Asset Management, LP 0.03% of their portfolio SAN FRANCISCO, CA 52,80052.8k $578.2k $578.2k 0.03% Unchanged
85 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 51,80251.8k $567.2k $567.2k 0.00% New
86 Cubist Systematic Strategies, LLC 0.01% of their portfolio STAMFORD, CT 51,74551.7k $566.6k $566.6k 0.01% Reduced -479.6k -479,636
87 Ascentis Independent Advisors 0.15% of their portfolio DALLAS, TX 50,00050.0k $547.5k $547.5k 0.15% Unchanged
88 CHARTWELL INVESTMENT PARTNERS, LLC 0.02% of their portfolio BERYWN, PA 49,02849.0k $536.9k $536.9k 0.02% Added +2.4k +2,373
89 VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio San Antonio, TX 48,75048.8k $533.8k $533.8k 0.00% Added +38.7k +38,673
90 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 48,59748.6k $532.1k $532.1k 0.00% Reduced -185.7k -185,699
91 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 48,04348.0k $526.1k $526.1k 0.00% New
92 AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio New York, NY 47,21347.2k $517.0k $517.0k 0.00% New
93 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 46,02346.0k $504.0k $504.0k 0.00% New
94 Aigen Investment Management, LP 0.07% of their portfolio NEW YORK, NY 42,26742.3k $462.8k $462.8k 0.07% New
95 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 40,88140.9k $447.6k $447.6k 0.00% Added +40.3k +40,262
96 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 40,48740.5k $443.3k $443.3k 0.00% New
97 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 39,37639.4k $431.2k $431.2k 0.00% New
98 Bayesian Capital Management, LP 0.05% of their portfolio Brooklyn, NY 38,90038.9k $426.0k $426.0k 0.05% New
99 Hennion & Walsh Asset Management, Inc. 0.02% of their portfolio Parsippany, NJ 38,43638.4k $421.0k $421.0k 0.02% New
100 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 37,63037.6k $412.0k $412.0k 0.00% New