Vault-13

CYMABAY THERAPEUTICS INC CBAY

COM · Common Stock · CUSIP 23257D103

141 institutional holders +23 vs Q4 2022
89,029,41689.0m shares reported held*
$776.5mreported value*
42 new 43 added 37 reduced 18 sold out net bought ≈ $210.2m (+24.0m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($350.7k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $8.72. Options: 8 managers hold calls ($6.5m notional), 8 hold puts ($3.4m).

Trends to Q1 2023

Institutional holders

Managers reporting a position, each quarter

050100150Q3 22: 100Q4 22: 118Q1 23: 141141Q3 22Q4 22Q1 23
Numbers
QuarterHolders
Q3 2022100
Q4 2022118
Q1 2023141

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1000100Q4 22: 53 bought or addedQ4 22: 35 cut or sold outQ4 22Q1 23: 85 bought or addedQ1 23: 55 cut or sold outQ1 23
Numbers
QuarterBought or addedCut or sold out
Q4 20225335
Q1 20238555

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$2m$4m$6m$8mQ3 22 calls: $865.0kQ3 22 puts: $520.0kQ3 22P/C 0.60Q4 22 calls: $2.8mQ4 22 puts: $1.5mQ4 22P/C 0.54Q1 23 calls: $6.5mQ1 23 puts: $3.4mQ1 23P/C 0.52
Numbers
QuarterCallsPutsP/C
Q3 2022$865.0k$520.0k0.60
Q4 2022$2.8m$1.5m0.54
Q1 2023$6.5m$3.4m0.52

Biggest buyers

JANUS HENDERSON GROUP PLC Added +6,252,380+6.3m
ADAGE CAPITAL PARTNERS GP, L.L.C. Added +3,899,400+3.9m
FRANKLIN RESOURCES INC Added +3,201,765+3.2m
PERCEPTIVE ADVISORS LLC Added +3,194,262+3.2m
Octagon Capital Advisors LP Added +2,711,718+2.7m
Bain Capital Life Sciences Investors, LLC New +2,500,000+2.5m
MILLENNIUM MANAGEMENT LLC Added +2,018,868+2.0m
Balyasny Asset Management L.P. Added +1,901,769+1.9m
Cormorant Asset Management, LP New +1,271,429+1.3m
TWO SIGMA INVESTMENTS, LP Added +1,030,443+1.0m

Biggest sellers

Commodore Capital LP Reduced -3,713,500-3.7m
TCG Crossover Management, LLC Reduced -2,857,143-2.9m
BAKER BROS. ADVISORS LP Sold out -2,170,464-2.2m
GREAT POINT PARTNERS LLC Reduced -1,042,500-1.0m
CITADEL ADVISORS LLC Reduced -1,034,929-1.0m
Logos Global Management LP Reduced -850,000-850.0k
683 Capital Management, LLC Reduced -700,000-700.0k
Sio Capital Management, LLC Sold out -555,610-555.6k
Walleye Capital LLC Sold out -488,894-488.9k
Nantahala Capital Management, LLC Reduced -460,456-460.5k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $1.6m178.0k shares
CITIGROUP INC Added $1.4m155.0k shares
Caption Management, LLC Added $1.0m120.0k shares
SIMPLEX TRADING, LLC Added $1.0m118.3k shares
GROUP ONE TRADING LLC Added $747.3k85.7k shares
JANE STREET GROUP, LLC New $453.4k52.0k shares
CITADEL ADVISORS LLC Reduced $327.9k37.6k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

CITIGROUP INC Added $1.4m155.0k shares
Caption Management, LLC Added $1.0m120.0k shares
SIMPLEX TRADING, LLC Added $347.0k39.9k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $315.7k36.2k shares
CITADEL ADVISORS LLC Added $188.4k21.6k shares
GROUP ONE TRADING LLC Added $136.9k15.7k shares
UBS Group AG New $31.4k3.6k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q1 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Avoro Capital Advisors LLC 1.33% of their portfolio NEW YORK, NY 10,300,00010.3m $89.8m $89.8m 1.33% Unchanged
2 JANUS HENDERSON GROUP PLC 0.04% of their portfolio LONDON, X0 7,496,0497.5m $65.4m $65.4m 0.04% Added +6.3m +6,252,380
3 Octagon Capital Advisors LP 5.75% of their portfolio NEW YORK, NY 4,570,9184.6m $39.9m $39.9m 5.75% Added +2.7m +2,711,718
4 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 4,449,6084.4m $38.8m $38.8m 0.00% Added +774.3k +774,310
5 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.09% of their portfolio Boston, MA 4,399,4004.4m $38.4m $38.4m 0.09% Added +3.9m +3,899,400
6 PERCEPTIVE ADVISORS LLC 1.01% of their portfolio NEW YORK, NY 3,903,2553.9m $34.0m $34.0m 1.01% Added +3.2m +3,194,262
7 FRANKLIN RESOURCES INC 0.01% of their portfolio San Mateo, CA 3,224,8623.2m $28.1m $28.1m 0.01% Added +3.2m +3,201,765
8 TCG Crossover Management, LLC 5.18% of their portfolio PALO ALTO, CA 3,048,2573.0m $26.6m $26.6m 5.18% Reduced -2.9m -2,857,143
9 MILLENNIUM MANAGEMENT LLC 0.03% of their portfolio NEW YORK, NY 2,949,0562.9m $25.7m $25.7m 0.03% Added +2.0m +2,018,868
10 BlackRock Inc. 0.00% of their portfolio New York, NY 2,650,0772.7m $23.1m $23.1m 0.00% Added +634.6k +634,577
11 Bain Capital Life Sciences Investors, LLC 2.72% of their portfolio Boston, MA 2,500,0002.5m $21.8m $21.8m 2.72% New
12 Commodore Capital LP 2.69% of their portfolio NEW YORK, NY 2,025,0002.0m $17.7m $17.7m 2.69% Reduced -3.7m -3,713,500
13 Balyasny Asset Management L.P. 0.06% of their portfolio Chicago, IL 1,957,0682.0m $17.1m $17.1m 0.06% Added +1.9m +1,901,769
14 Laurion Capital Management LP 0.76% of their portfolio NEW YORK, NY 1,922,1031.9m $16.8m $16.8m 0.76% Added +306.2k +306,203
15 Nantahala Capital Management, LLC 1.50% of their portfolio NEW CANAAN, CT 1,790,1031.8m $15.6m $15.6m 1.50% Reduced -460.5k -460,456
16 Foresite Capital Management IV, LLC 8.09% of their portfolio WEST HOLLYWOOD, CA 1,787,0941.8m $15.6m $15.6m 8.09% Unchanged
17 Saturn V Capital Management LP 10.61% of their portfolio AUSTIN, TX 1,629,4641.6m $14.2m $14.2m 10.61% Added +17.7k +17,686
18 TWO SIGMA INVESTMENTS, LP 0.04% of their portfolio NEW YORK, NY 1,419,5401.4m $12.4m $12.4m 0.04% Added +1.0m +1,030,443
19 TWO SIGMA ADVISERS, LP 0.03% of their portfolio NEW YORK, NY 1,414,8381.4m $12.3m $12.3m 0.03% Added +1.0m +1,011,300
20 Lynx1 Capital Management LP 9.96% of their portfolio DORADO, PR 1,369,9271.4m $11.9m $11.9m 9.96% Reduced -283.6k -283,568
21 Cormorant Asset Management, LP 0.73% of their portfolio BOSTON, MA 1,271,4291.3m $11.1m $11.1m 0.73% New
22 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.02% of their portfolio BALA CYNWYD, PA 1,184,4231.2m $10.3m $10.3m 0.02% Added +782.8k +782,755
23 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 1,183,2361.2m $10.3m $10.3m 0.00% Reduced -131.3k -131,286
24 Affinity Asset Advisors, LLC 3.63% of their portfolio NEW YORK, NY 1,083,1181.1m $9.4m $9.4m 3.63% Reduced -60.4k -60,413
25 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 992,381992.4k $8.7m $8.7m 0.00% Added +719.3k +719,302
26 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 954,627954.6k $8.3m $8.3m 0.00% Added +815.5k +815,494
27 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 904,958905.0k $7.9m $7.9m 0.00% Added +115.0k +115,044
28 ACUTA CAPITAL PARTNERS, LLC 5.96% of their portfolio REDWOOD CITY, CA 878,500878.5k $7.7m $7.7m 5.96% Reduced -136.5k -136,500
29 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 773,346773.3k $6.7m $6.7m 0.00% Added +688.1k +688,132
30 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 669,036669.0k $5.8m $5.8m 0.00% Added +330.8k +330,763
31 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.03% of their portfolio JUPITER, FL 643,812643.8k $5.6m $5.6m 0.03% New
32 JENNISON ASSOCIATES LLC 0.00% of their portfolio NEW YORK, NY 623,663623.7k $5.4m $5.4m 0.00% New
33 Altium Capital Management LLC 3.23% of their portfolio NEW YORK, NY 620,000620.0k $5.4m $5.4m 3.23% Reduced -405.0k -405,000
34 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 571,499571.5k $5.0m $5.0m 0.01% Added +457.8k +457,816
35 D. E. Shaw & Co., Inc. 0.01% of their portfolio New York, NY 549,044549.0k $4.8m $4.8m 0.01% Added +280.8k +280,849
36 Versant Venture Management, LLC 9.88% of their portfolio San Francisco, CA 543,753543.8k $4.7m $4.7m 9.88% Unchanged
37 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 542,407542.4k $4.7m $4.7m 0.00% Added +539.4k +539,415
38 Cubist Systematic Strategies, LLC 0.04% of their portfolio STAMFORD, CT 531,381531.4k $4.6m $4.6m 0.04% Added +478.1k +478,052
39 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 525,693525.7k $4.6m $4.6m 0.00% Added +417.9k +417,851
40 GREAT POINT PARTNERS LLC 0.87% of their portfolio Greenwich, CT 507,500507.5k $4.4m $4.4m 0.87% Reduced -1.0m -1,042,500
41 683 Capital Management, LLC 0.39% of their portfolio NEW YORK, NY 500,000500.0k $4.4m $4.4m 0.39% Reduced -700.0k -700,000
42 RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio NEW YORK, NY 481,500481.5k $4.2m $4.2m 0.01% Reduced -24.4k -24,400
43 Hudson Bay Capital Management LP 0.02% of their portfolio STAMFORD, CT 480,172480.2k $4.2m $4.2m 0.02% Reduced -217.3k -217,328
44 Logos Global Management LP 0.50% of their portfolio San Francisco, CA 400,000400.0k $3.5m $3.5m 0.50% Reduced -850.0k -850,000
45 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 395,089395.1k $3.4m $3.4m 0.00% Added +267.9k +267,893
46 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.02% of their portfolio TORONTO, A6 386,600386.6k $3.4m $3.4m 0.02% New
47 HRT FINANCIAL LP 0.04% of their portfolio NEW YORK, NY 385,676385.7k $3.4m $3.4m 0.04% Added +311.5k +311,482
48 HighVista Strategies LLC 2.47% of their portfolio BOSTON, MA 347,786347.8k $3.0m $3.0m 2.47% Reduced -47.5k -47,546
49 Connor, Clark & Lunn Investment Management Ltd. 0.02% of their portfolio VANCOUVER, A1 340,638340.6k $3.0m $3.0m 0.02% Added +50.5k +50,464
50 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 325,886325.9k $2.8m $2.8m 0.00% Reduced -1.0m -1,034,929
51 Informed Momentum Co LLC 0.54% of their portfolio SOLANA BEACH, CA 316,594316.6k $2.8m $2.8m 0.54% Reduced -233.9k -233,876
52 Woodline Partners LP 0.04% of their portfolio San Francisco, CA 285,717285.7k $2.5m $2.5m 0.04% New
53 MARSHALL WACE, LLP 0.01% of their portfolio LONDON, X0 243,181243.2k $2.1m $2.1m 0.01% Added +161.4k +161,401
54 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 234,296234.3k $2.0m $2.0m 0.00% Added +4.7k +4,709
55 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 209,477209.5k $1.8m $1.8m 0.00% Added +69.2k +69,198
56 Swiss National Bank 0.00% of their portfolio ZURICH, V8 182,700182.7k $1.6m $1.6m 0.00% New
57 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 172,714172.7k $1.5m $1.5m 0.00% Added +172.2k +172,193
58 Artia Global Partners LP 0.59% of their portfolio MIAMI, FL 169,277169.3k $1.5m $1.5m 0.59% New
59 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 152,487152.5k $1.3m $1.3m 0.00% New
60 Graham Capital Management, L.P. 0.04% of their portfolio ROWAYTON, CT 144,974145.0k $1.3m $1.3m 0.04% Added +117.9k +117,896
61 ClariVest Asset Management LLC 0.05% of their portfolio SAN DIEGO, CA 131,141131.1k $1.1m $1.1m 0.05% Reduced -159 -159
62 Carlyle Group Inc. 0.03% of their portfolio WASHINGTON, DC 131,036131.0k $1.1m $1.1m 0.03% New
63 LPL Financial LLC 0.00% of their portfolio FORT MILL, SC 118,829118.8k $1.0m $1.0m 0.00% Added +2.6k +2,616
64 Verition Fund Management LLC 0.01% of their portfolio GREENWICH, CT 100,342100.3k $875.0k $875.0k 0.01% New
65 Lion Point Capital, LP 0.48% of their portfolio NEW YORK, NY 99,42599.4k $867.0k $867.0k 0.48% Reduced -120.0k -120,000
66 Squarepoint Ops LLC 0.01% of their portfolio NEW YORK, NY 93,88293.9k $818.7k $818.7k 0.01% Added +83.9k +83,855
67 Campbell & CO Investment Adviser LLC 0.13% of their portfolio BALTIMORE, MD 79,47979.5k $693.1k $693.1k 0.13% New
68 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 78,12478.1k $681.2k $681.2k 0.00% New
69 Harvest Investment Services, LLC 0.52% of their portfolio Oakbrook Terrace, IL 76,95677.0k $671.1k $671.1k 0.52% New
70 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 74,39174.4k $648.7k $648.7k 0.00% New
71 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 72,61172.6k $634.0k $634.0k 0.00% Reduced -56.8k -56,806
72 UBS Group AG 0.00% of their portfolio ZURICH, V8 69,80069.8k $608.7k $608.7k 0.00% Reduced -215.9k -215,936
73 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 69,03569.0k $602.0k $602.0k 0.00% New
74 LMR Partners LLP 0.01% of their portfolio LONDON, X0 66,25166.3k $577.7k $577.7k 0.01% Added +25.7k +25,747
75 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 65,74665.7k $573.3k $573.3k 0.00% New
76 Trexquant Investment LP 0.02% of their portfolio STAMFORD, CT 63,88663.9k $557.1k $557.1k 0.02% New
77 ALPS ADVISORS INC 0.00% of their portfolio Denver, CO 62,38062.4k $544.0k $544.0k 0.00% Added +4.9k +4,874
78 Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio ST. PETERSBURG, FL 60,15960.2k $524.6k $524.6k 0.00% New
79 MIRABELLA FINANCIAL SERVICES LLP 0.09% of their portfolio London, X0 58,18058.2k $507.3k $507.3k 0.09% Added +33.3k +33,307
80 Baker Avenue Asset Management, LP 0.02% of their portfolio SAN FRANCISCO, CA 52,80052.8k $460.4k $460.4k 0.02% Unchanged
81 MACKENZIE FINANCIAL CORP 0.00% of their portfolio TORONTO ONTARIO, A6 50,17850.2k $437.6k $437.6k 0.00% New
82 Ascentis Independent Advisors 0.24% of their portfolio DALLAS, TX 50,00050.0k $436.0k $436.0k 0.24% First filing
83 CHARTWELL INVESTMENT PARTNERS, LLC 0.02% of their portfolio BERYWN, PA 46,65546.7k $406.0k $406.0k 0.02% New
84 BAMCO INC /NY/ 0.00% of their portfolio NEW YORK, NY 44,20644.2k $385.5k $385.5k 0.00% Reduced -28.4k -28,389
85 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 39,98140.0k $348.6k $348.6k 0.00% Added +258 +258
86 Connacht Asset Management LP 0.98% of their portfolio New York, NY 39,12739.1k $341.2k $341.2k 0.98% New
87 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 38,48038.5k $335.5k $335.5k 0.00% Added +3.9k +3,914
88 Legal & General Group Plc 0.00% of their portfolio London, X0 36,58536.6k $319.0k $319.0k 0.00% New
89 Diametric Capital, LP 0.14% of their portfolio BOSTON, MA 33,70633.7k $293.9k $293.9k 0.14% New
90 CARY STREET PARTNERS INVESTMENT ADVISORY LLC 0.02% of their portfolio RICHMOND, VA 30,00030.0k $261.6k $261.6k 0.02% Reduced -10.0k -10,000
91 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 26,97627.0k $235.2k $235.2k 0.00% Reduced -20.8k -20,799
92 TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio AUSTIN, TX 26,08626.1k $227.0k $227.0k 0.00% New
93 CAXTON ASSOCIATES LP 0.04% of their portfolio NEW YORK, NY 25,72525.7k $224.3k $224.3k 0.04% Reduced -47.9k -47,924
94 FIRST MANHATTAN CO. LLC. 0.00% of their portfolio NEW YORK, NY 25,00025.0k $218.0k $218.0k 0.00% Unchanged
95 Composition Wealth, LLC 0.01% of their portfolio LOS ANGELES, CA 25,00025.0k $218.0k $218.0k 0.01% Unchanged
96 ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio PHOENIX, AZ 24,53624.5k $214.0k $214.0k 0.00% New
97 LVM CAPITAL MANAGEMENT LTD/MI 0.03% of their portfolio PORTAGE, MI 23,00023.0k $201.0k $201.0k 0.03% Added +13.0k +13,000
98 FMR LLC 0.00% of their portfolio BOSTON, MA 22,50822.5k $196.3k $196.3k 0.00% Added +11.3k +11,268
99 RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio ST PETERSBURG, FL 22,16922.2k $193.3k $193.3k 0.00% Reduced -6.6k -6,612
100 Point72 Asset Management, L.P. 0.00% of their portfolio STAMFORD, CT 20,59720.6k $179.6k $179.6k 0.00% New