CRYOPORT INC CYRX
COM PAR $0.001 · Common Stock · CUSIP 229050307 · ISIN US2290503075
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersBrentwood, TN
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($393.0k this quarter). Holder counts are more reliable. Shares outstanding: 50.1m as of 2025-10-31, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $9.48. Options: 8 managers hold calls ($13.8m notional), 7 hold puts ($5.5m).
Trends to Q3 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 195 |
| Q4 2022 | 172 |
| Q1 2023 | 181 |
| Q2 2023 | 180 |
| Q3 2023 | 160 |
| Q4 2023 | 146 |
| Q1 2024 | 152 |
| Q2 2024 | 162 |
| Q3 2024 | 154 |
| Q4 2024 | 162 |
| Q1 2025 | 154 |
| Q2 2025 | 161 |
| Q3 2025 | 160 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2023 | 60 | 81 |
| Q1 2024 | 69 | 65 |
| Q2 2024 | 80 | 78 |
| Q3 2024 | 73 | 75 |
| Q4 2024 | 84 | 66 |
| Q1 2025 | 68 | 77 |
| Q2 2025 | 95 | 57 |
| Q3 2025 | 76 | 72 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2024 | $2.2m | $70.7k | 0.03 |
| Q1 2025 | $2.0m | $1.8m | 0.91 |
| Q2 2025 | $4.5m | $3.9m | 0.85 |
| Q3 2025 | $13.8m | $5.5m | 0.40 |
Biggest buyers
| MAK CAPITAL ONE LLC | New | +818.2k |
| UBS Group AG | Added | +705.6k |
| Meros Investment Management, LP | New | +549.7k |
| MILLENNIUM MANAGEMENT LLC | Added | +408.3k |
| Assenagon Asset Management S.A. | Added | +408.3k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Added | +387.4k |
| Nuveen, LLC | Added | +346.7k |
| CITADEL ADVISORS LLC | Added | +266.5k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +213.0k |
| JPMORGAN CHASE & CO | Added | +193.0k |
Biggest sellers
| BROWN CAPITAL MANAGEMENT LLC | Reduced | -1.2m |
| NEW YORK STATE COMMON RETIREMENT FUND | Reduced | -1.1m |
| AXA S.A. | Sold out | -735.8k |
| FRED ALGER MANAGEMENT, LLC | Reduced | -578.4k |
| KENNEDY CAPITAL MANAGEMENT LLC | Sold out | -547.4k |
| Thematics Asset Management | Reduced | -276.3k |
| Trexquant Investment LP | Reduced | -261.0k |
| ROYAL BANK OF CANADA | Reduced | -210.3k |
| READYSTATE ASSET MANAGEMENT LP | Reduced | -180.6k |
| BlackRock, Inc. | Reduced | -121.0k |
Biggest calls
| GROUP ONE TRADING LLC | Added | $3.6m378.7k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.6m274.9k shares |
| Caption Management, LLC | Added | $2.1m225.2k shares |
| CITADEL ADVISORS LLC | Added | $1.9m197.6k shares |
| PEAK6 LLC | Added | $1.8m190.8k shares |
| JANE STREET GROUP, LLC | Added | $886.4k93.5k shares |
| SIMPLEX TRADING, LLC | Added | $648.0k68.4k shares |
| WOLVERINE TRADING, LLC | Added | $293.6k31.2k shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $1.4m152.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $1.3m134.0k shares |
| Caption Management, LLC | Unchanged | $1.2m125.0k shares |
| SIMPLEX TRADING, LLC | Added | $605.0k63.9k shares |
| GROUP ONE TRADING LLC | Reduced | $502.4k53.0k shares |
| WOLVERINE TRADING, LLC | Added | $277.6k29.5k shares |
| JANE STREET GROUP, LLC | Added | $209.5k22.1k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| CADIAN CAPITAL MANAGEMENT, LP 13G · institution -4.2 pts · filed 2026-08-14 | 5.8% |
Fell to 5% or below in the last year: MORGAN STANLEY (4.5%, 2026-08-13), INTEGRATED CORE STRATEGIES (US) LLC (3.4%, 2026-07-29), VANGUARD GROUP INC (0.0%, 2026-03-26), BROWN CAPITAL MANAGEMENT LLC (2.2%, 2026-02-17)
Insider purchases and sales in Q3 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2023 | 0 | — | 1 | $29.0k | — |
| Q1 2024 | 0 | — | 4 | $1.1m | — |
| Q2 2024 | 0 | — | 2 | $154.7k | — |
| Q3 2024 | 0 | — | 2 | $60.4k | $33.5k |
| Q4 2024 | 0 | — | 3 | $1.6m | $1.5m |
| Q1 2025 | 0 | — | 4 | $131.5k | — |
| Q2 2025 | 0 | — | 4 | $3.0m | — |
| Q3 2025 | 0 | — | 3 | $661.3k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-09-11 | Hariri Robert J Director | Sold | $242.8k25.0k shares |
| 2025-08-22 | Hariri Robert J Director | Sold | $43.0k5.0k shares |
| 2025-08-19 | STEFANOVICH ROBERT Chief Financial Officer | Sold | $80.6k9.3k shares |
| 2025-07-22 | Mandalam Ramkumar Director | Sold | $294.9k40.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2025
| Manager | Shares | Change |
|---|---|---|
| CADIAN CAPITAL MANAGEMENT, LP 2.81% of their portfolio | 5.0m $47.2m | Added +14.8k |
| MORGAN STANLEY 0.00% of their portfolio | 4.6m $43.7m | Added +36.9k |
| BlackRock, Inc. 0.00% of their portfolio | 4.0m $37.9m | Reduced -121.0k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.9m $27.1m | Added +69.5k |
| BROWN CAPITAL MANAGEMENT LLC 1.02% of their portfolio | 2.6m $24.9m | Reduced -1.2m |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 2.6m $24.8m | Added +408.3k |
| FRED ALGER MANAGEMENT, LLC 0.07% of their portfolio | 1.8m $16.9m | Reduced -578.4k |
| Thematics Asset Management 0.70% of their portfolio | 1.6m $15.5m | Reduced -276.3k |
| Assenagon Asset Management S.A. 0.02% of their portfolio | 1.5m $14.2m | Added +408.3k |
| UBS Group AG 0.00% of their portfolio | 1.3m $12.6m | Added +705.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.2m $11.5m | Added +7.2k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 994.1k $9.4m | Added +4.9k |
| STATE STREET CORP 0.00% of their portfolio | 963.8k $9.1m | Added +22.3k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 934.8k $8.9m | Added +98.1k |
| MAK CAPITAL ONE LLC 1.55% of their portfolio | 818.2k $7.8m | New |
| SILVERCREST ASSET MANAGEMENT GROUP LLC 0.05% of their portfolio | 718.7k $6.8m | Reduced -19.9k |
| ACADIAN ASSET MANAGEMENT LLC 0.01% of their portfolio | 671.3k $6.4m | Added +122.5k |
| AXA Investment Managers S.A. 0.02% of their portfolio | 635.1k $6.0m | First filing |
| Meros Investment Management, LP 2.22% of their portfolio | 549.7k $5.2m | New |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.02% of their portfolio | 524.3k $5.0m | Added +387.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 521.1k $4.9m | Added +123.7k |
| Nuveen, LLC 0.00% of their portfolio | 496.7k $4.7m | Added +346.7k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 486.5k $4.6m | Added +81.0k |
| Blackstone Inc. 0.02% of their portfolio | 453.4k $4.3m | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 433.0k $4.1m | Added +193.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 429.4k $4.1m | Added +9.6k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 389.2k $3.7m | Added +213.0k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 388.6k $3.7m | Added +266.5k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 386.8k $3.7m | Added +4.1k |
| TOCQUEVILLE ASSET MANAGEMENT L.P. 0.05% of their portfolio | 355.0k $3.4m | Unchanged |
| NEEDHAM INVESTMENT MANAGEMENT LLC 0.20% of their portfolio | 307.5k $2.9m | Unchanged |
| READYSTATE ASSET MANAGEMENT LP 0.14% of their portfolio | 304.5k $2.9m | Reduced -180.6k |
| Bullseye Asset Management LLC 1.47% of their portfolio | 296.6k $2.8m | Added +36.4k |
| TUDOR INVESTMENT CORP ET AL 0.02% of their portfolio | 290.7k $2.8m | Reduced -2.8k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 290.2k $2.8m | Reduced -9.2k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 278.0k $2.6m | Reduced -116.5k |
| Archon Capital Management LLC 1.41% of their portfolio | 250.3k $2.4m | Added +77.5k |
| PHILADELPHIA TRUST CO 0.16% of their portfolio | 243.5k $2.3m | Reduced -8.8k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 223.1k $2.1m | Reduced -10.7k |
| PERKINS CAPITAL MANAGEMENT INC 1.73% of their portfolio | 207.3k $2.0m | Added +37.2k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 174.1k $1.7m | Reduced -13.0k |
| Empire Financial Management Company, LLC 0.36% of their portfolio | 167.0k $1.6m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 166.1k $1.6m | Added +58.6k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 155.6k $1.5m | Added +1.4k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 140.7k $1.3m | Reduced -210.3k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 140.7k $1.3m | Added +88.5k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 133.0k $1.3m | Added +67.9k |
| SG Americas Securities, LLC 0.00% of their portfolio | 127.3k $1.2m | Added +110.6k |
| MARATHON CAPITAL MANAGEMENT 0.24% of their portfolio | 110.0k $1.0m | Reduced -11.7k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 109.7k $1.0m | Added +109.0k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 109.6k $1.0m | Added +20.8k |
| Conestoga Capital Advisors, LLC 0.02% of their portfolio | 105.2k $997.2k | Reduced -5.4k |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 93.7k $888.3k | Added +7.3k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 91.7k $869.2k | Added +57.7k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 91.4k $866.8k | Reduced -657 |
| BARCLAYS PLC 0.00% of their portfolio | 90.0k $853.1k | Reduced -28.4k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 84.9k $805.2k | Unchanged |
| Invesco Ltd. 0.00% of their portfolio | 80.9k $767.3k | Added +12.5k |
| Squarepoint Ops LLC 0.00% of their portfolio | 79.8k $756.3k | New |
| SEGALL BRYANT & HAMILL, LLC 0.01% of their portfolio | 68.8k $652.2k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 67.6k $641.0k | Added +129 |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 63.5k $562.4k | Reduced -50 |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 61.1k $579.3k | Reduced -125 |
| Caption Management, LLC 0.03% of their portfolio | 60.0k $568.8k | Unchanged |
| Geneos Wealth Management Inc. 0.01% of their portfolio | 60.0k $568.8k | Unchanged |
| Williams Jones Wealth Management, LLC. 0.01% of their portfolio | 59.1k $560.2k | Reduced -1.5k |
| Brevan Howard Capital Management LP 0.01% of their portfolio | 57.1k $540.9k | Added +33.7k |
| Trexquant Investment LP 0.01% of their portfolio | 56.2k $532.9k | Reduced -261.0k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 54.1k $512.5k | Added +13.6k |
| Penbrook Management LLC 0.35% of their portfolio | 52.8k $500.3k | Reduced -42.2k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 51.7k $487.8k | Reduced -9.5k |
| Evanson Asset Management, LLC 0.03% of their portfolio | 50.0k $474.0k | Unchanged |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 49.0k $464.4k | Reduced -12.3k |
| Inspire Investing, LLC 0.04% of their portfolio | 47.8k $453.4k | Reduced -3.6k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 45.1k $427.5k | New |
| SIERRA SUMMIT ADVISORS LLC 0.07% of their portfolio | 45.1k $427.2k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 37.3k $353.8k | Added +4.3k |
| ALGERT GLOBAL LLC 0.01% of their portfolio | 35.3k $334.3k | Reduced -6.2k |
| Mariner, LLC 0.00% of their portfolio | 34.2k $323.9k | Reduced -8.7k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 33.5k $317.4k | Reduced -2.0k |
| Headlands Technologies LLC 0.03% of their portfolio | 33.1k $313.8k | New |
| SIMPLEX TRADING, LLC 0.01% of their portfolio | 32.8k $310.0k | Added +6.5k |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 0.00% of their portfolio | 31.6k $299.1k | Added +9.8k |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 30.1k $285.3k | New |
| Quantinno Capital Management LP 0.00% of their portfolio | 29.4k $278.9k | Added +10.8k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 27.5k $260.4k | Reduced -615 |
| Creative Planning 0.00% of their portfolio | 26.1k $247.1k | Added +13.2k |
| State of Wyoming 0.03% of their portfolio | 25.5k $242.1k | Added +11.3k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 23.1k $218.8k | Reduced -2.9k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 23.0k $217.8k | Reduced -3.8k |
| Susquehanna Portfolio Strategies, LLC 0.00% of their portfolio | 22.0k $208.1k | New |
| LPL Financial LLC 0.00% of their portfolio | 21.9k $207.4k | Reduced -24.1k |
| MARTINGALE ASSET MANAGEMENT L P 0.01% of their portfolio | 21.5k $204.0k | New |
| FMR LLC 0.00% of their portfolio | 20.7k $196.1k | Reduced -825 |
| NRI Wealth Management LC 0.10% of their portfolio | 19.1k $181.4k | Unchanged |
| Petrus Trust Company, LTA 0.02% of their portfolio | 18.5k $175.7k | New |
| Cornerstone Investment Partners, LLC 0.01% of their portfolio | 18.3k $173.5k | New |
| CWM, LLC 0.00% of their portfolio | 17.4k $165.0k | Reduced -319 |
| Campbell & CO Investment Adviser LLC 0.01% of their portfolio | 17.3k $163.7k | New |
| Arax Advisory Partners 0.00% of their portfolio | 17.0k $161.2k | Added +16.9k |