COMPASS PATHWAYS PLC CMPS
SPONSORED ADS · ADR · CUSIP 20451W101 · ISIN US20451W1018
British biotechnology company developing psilocybin-based treatments for mental health disorders
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersLondon, United Kingdom
- Founded2016
- Websitecompasspathways.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($3.7m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $6.90. Options: 11 managers hold calls ($20.0m notional), 7 hold puts ($6.1m).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 115 |
| Q4 2022 | 112 |
| Q1 2023 | 103 |
| Q2 2023 | 98 |
| Q3 2023 | 114 |
| Q4 2023 | 127 |
| Q1 2024 | 119 |
| Q2 2024 | 123 |
| Q3 2024 | 131 |
| Q4 2024 | 133 |
| Q1 2025 | 136 |
| Q2 2025 | 141 |
| Q3 2025 | 157 |
| Q4 2025 | 168 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 45 | 52 |
| Q2 2024 | 52 | 36 |
| Q3 2024 | 49 | 44 |
| Q4 2024 | 52 | 57 |
| Q1 2025 | 61 | 45 |
| Q2 2025 | 60 | 58 |
| Q3 2025 | 87 | 43 |
| Q4 2025 | 66 | 65 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $1.6m | $973.9k | 0.62 |
| Q2 2025 | $6.0m | $2.1m | 0.34 |
| Q3 2025 | $20.0m | $5.1m | 0.26 |
| Q4 2025 | $20.0m | $6.1m | 0.30 |
Biggest buyers
| TORONTO DOMINION BANK | Added | +1.5m |
| Siren, L.L.C. | New | +1.0m |
| Point72 Asset Management, L.P. | New | +844.8k |
| D. E. Shaw & Co., Inc. | Added | +775.1k |
| Eagle Health Investments LP | Added | +583.9k |
| TWO SIGMA INVESTMENTS, LP | Added | +569.0k |
| HighVista Strategies LLC | New | +498.9k |
| Ikarian Capital, LLC | New | +400.0k |
| Propel Bio Management, LLC | Added | +351.8k |
| CITADEL ADVISORS LLC | New | +311.5k |
Biggest sellers
| TANG CAPITAL MANAGEMENT LLC | Sold out | -2.2m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -1.3m |
| Nantahala Capital Management, LLC | Reduced | -1.3m |
| HSBC HOLDINGS PLC | Sold out | -1.3m |
| Ally Bridge Group (NY) LLC | Sold out | -1.0m |
| PFM Health Sciences, LP | Reduced | -883.2k |
| AMERIPRISE FINANCIAL INC | Reduced | -563.7k |
| Deep Track Capital, LP | Reduced | -525.3k |
| Balyasny Asset Management L.P. | Sold out | -395.0k |
| STEMPOINT CAPITAL LP | Sold out | -275.6k |
Biggest calls
| Ally Bridge Group (NY) LLC | Reduced | $7.6m1.1m shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $6.5m938.1k shares |
| DLD Asset Management, LP | Reduced | $1.7m249.1k shares |
| GROUP ONE TRADING LLC | Reduced | $1.3m191.7k shares |
| SIMPLEX TRADING, LLC | Added | $966.7k140.1k shares |
| JANE STREET GROUP, LLC | New | $687.2k99.6k shares |
| GOLDMAN SACHS GROUP INC | Reduced | $579.6k84.0k shares |
| CITADEL ADVISORS LLC | Reduced | $455.4k66.0k shares |
| TUDOR INVESTMENT CORP ET AL | Reduced | $124.2k18.0k shares |
| Walleye Capital LLC | Reduced | $46.9k6.8k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $3.3m476.5k shares |
| DLD Asset Management, LP | Reduced | $1.3m188.3k shares |
| CITADEL ADVISORS LLC | Added | $808.7k117.2k shares |
| TUDOR INVESTMENT CORP ET AL | Added | $338.1k49.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $149.7k21.7k shares |
| GROUP ONE TRADING LLC | Reduced | $99.4k14.4k shares |
| JANE STREET GROUP, LLC | New | $81.4k11.8k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Deep Track Capital, LP 13G · passive investor new · filed 2025-01-17 | 10.0% |
| RTW INVESTMENTS, LP 13G · institution no change · filed 2026-05-15 | 9.9% |
| ATAI Life Sciences N.V. 13D · may seek influence -1.5 pts · filed 2025-10-29 | 6.0% |
| BIT Capital GmbH 13G · institution new · filed 2026-10-28 | 5.9% |
Fell to 5% or below in the last year: AtaiBeckley Inc. (5.0%, 2026-02-17), Nantahala Capital Management, LLC (3.6%, 2025-11-14), Vivo Opportunity Fund Holdings, L.P. (3.2%, 2025-11-14)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2024 | 0 | — | 2 | $3.8m | $3.8m |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
None reported in Q4 2025.
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| RTW INVESTMENTS, LP 0.61% of their portfolio | 8.8m $60.4m | Added +50.0k |
| Deep Track Capital, LP 1.15% of their portfolio | 7.3m $50.6m | Reduced -525.3k |
| GMT Capital Corp 1.02% of their portfolio | 2.8m $19.6m | Unchanged |
| TORONTO DOMINION BANK 0.03% of their portfolio | 2.5m $17.4m | Added +1.5m |
| ARK Investment Management LLC 0.10% of their portfolio | 2.2m $14.9m | Added +34.9k |
| UBS Group AG 0.00% of their portfolio | 2.0m $14.1m | Reduced -106.0k |
| TWO SIGMA INVESTMENTS, LP 0.02% of their portfolio | 1.6m $11.3m | Added +569.0k |
| Jefferies Financial Group Inc. 0.09% of their portfolio | 1.6m $10.9m | Added +200.0k |
| Eagle Health Investments LP 2.30% of their portfolio | 1.5m $10.5m | Added +583.9k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 1.5m $10.0m | Added +775.1k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 1.4m $9.6m | Reduced -1.3m |
| Aisling Capital Management LP 1.73% of their portfolio | 1.2m $8.3m | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 1.1m $7.8m | Added +107.2k |
| Siren, L.L.C. 0.21% of their portfolio | 1.0m $6.9m | New |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 967.8k $6.7m | Added +16.6k |
| Propel Bio Management, LLC 5.08% of their portfolio | 861.8k $5.9m | Added +351.8k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 856.5k $5.9m | Added +308.0k |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 844.8k $5.8m | New |
| Kalehua Capital Management LLC 5.59% of their portfolio | 819.7k $5.7m | First filing |
| DAFNA Capital Management LLC 1.30% of their portfolio | 811.0k $5.6m | Unchanged |
| PFM Health Sciences, LP 0.54% of their portfolio | 779.6k $5.4m | Reduced -883.2k |
| NEXTBio Capital Management LP 3.05% of their portfolio | 752.6k $5.2m | First filing |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 645.1k $4.5m | Reduced -563.7k |
| BlackRock, Inc. 0.00% of their portfolio | 594.3k $4.1m | Added +171.5k |
| CenterBook Partners LP 0.20% of their portfolio | 578.8k $4.0m | Reduced -57.3k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 570.5k $3.8m | Unchanged |
| HighVista Strategies LLC 0.89% of their portfolio | 498.9k $3.4m | New |
| Blue Owl Capital Holdings LP 1.00% of their portfolio | 469.9k $3.2m | Reduced -135.0k |
| Nantahala Capital Management, LLC 0.18% of their portfolio | 443.3k $3.1m | Reduced -1.3m |
| Hennion & Walsh Asset Management, Inc. 0.10% of their portfolio | 424.8k $2.9m | Added +266.9k |
| Ikarian Capital, LLC 0.36% of their portfolio | 400.0k $2.8m | New |
| Squadron Capital Management LLC 1.20% of their portfolio | 388.3k $2.7m | First filing |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 336.7k $2.3m | Added +32.4k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 311.5k $2.1m | New |
| Simplify Asset Management Inc. 0.03% of their portfolio | 290.0k $2.0m | Unchanged |
| BIT Capital GmbH 0.09% of their portfolio | 288.8k $2.0m | Added +279.4k |
| Founders Fund VII Management, LLC 94.84% of their portfolio | 278.9k $1.9m | Unchanged |
| Susquehanna Portfolio Strategies, LLC 0.03% of their portfolio | 275.8k $1.9m | Unchanged |
| Sumitomo Mitsui Trust Group, Inc. 0.00% of their portfolio | 247.3k $1.7m | Reduced -29.7k |
| Amova Asset Management Americas, Inc. 0.02% of their portfolio | 247.3k $1.7m | Reduced -29.7k |
| AdvisorShares Investments LLC 0.27% of their portfolio | 230.9k $1.6m | Reduced -1.4k |
| Legal & General Group Plc 0.00% of their portfolio | 218.4k $1.5m | New |
| Brown University 1.04% of their portfolio | 214.2k $1.5m | Unchanged |
| Affinity Asset Advisors, LLC 0.10% of their portfolio | 200.0k $1.4m | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 189.8k $1.3m | Reduced -130.3k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 181.2k $1.2m | Added +8.0k |
| Y-Intercept (Hong Kong) Ltd 0.03% of their portfolio | 174.3k $1.2m | New |
| Jump Financial, LLC 0.01% of their portfolio | 167.0k $1.2m | Reduced -23.0k |
| STABLEFORD CAPITAL II LLC 0.40% of their portfolio | 160.6k $1.1m | Reduced -4.0k |
| Saba Capital Management, L.P. 0.03% of their portfolio | 151.0k $1.0m | Unchanged |
| BRIDGER MANAGEMENT, LLC 0.65% of their portfolio | 147.2k $1.0m | Unchanged |
| Bellevue Group AG 0.02% of their portfolio | 142.2k $981.5k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 139.9k $965.6k | Reduced -2.7k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 127.0k $876.2k | Reduced -73.8k |
| Palo Alto Investors LP 0.11% of their portfolio | 115.6k $797.8k | New |
| BOOTHBAY FUND MANAGEMENT, LLC 0.02% of their portfolio | 111.1k $766.5k | Reduced -88.9k |
| SIMPLEX TRADING, LLC 0.02% of their portfolio | 105.2k $726.1k | Reduced -15.7k |
| Parkman Healthcare Partners LLC 0.07% of their portfolio | 99.5k $686.4k | Reduced -528 |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.04% of their portfolio | 85.1k $587.4k | Added +27.5k |
| Engineers Gate Manager LP 0.01% of their portfolio | 79.8k $550.6k | New |
| STATE STREET CORP 0.00% of their portfolio | 78.8k $543.7k | Reduced -1.2k |
| Corient Private Wealth LP 0.00% of their portfolio | 76.9k $530.4k | Added +39.6k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.02% of their portfolio | 71.9k $496.0k | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 63.0k $434.4k | Unchanged |
| Intellectus Partners, LLC 0.08% of their portfolio | 61.0k $420.9k | Added +11.0k |
| FOX RUN MANAGEMENT, L.L.C. 0.06% of their portfolio | 60.8k $419.7k | New |
| Lion Point Capital, LP 2.07% of their portfolio | 58.0k $400.2k | Unchanged |
| XTX Topco Ltd 0.01% of their portfolio | 56.8k $391.8k | Added +46.6k |
| FLAX POND CAPITAL, LLC 0.27% of their portfolio | 52.8k $364.4k | First filing |
| FreeGulliver LLC 0.14% of their portfolio | 45.0k $310.5k | New |
| FLAGSHIP HARBOR ADVISORS, LLC 0.01% of their portfolio | 42.6k $293.9k | Reduced -3.8k |
| Seven Fleet Capital Management LP 0.19% of their portfolio | 40.0k $276.0k | First filing |
| Virtus Investment Advisers, LLC 0.07% of their portfolio | 39.5k $272.4k | Added +14.3k |
| Graham Capital Management, L.P. 0.01% of their portfolio | 36.1k $249.4k | Added +21.5k |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 34.7k $239.6k | New |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 33.5k $231.4k | Reduced -114.5k |
| HighTower Advisors, LLC 0.00% of their portfolio | 31.5k $217.3k | Added +19.9k |
| Conservest Capital Advisors, Inc. 0.02% of their portfolio | 25.4k $175.0k | Added +5.0k |
| HRT FINANCIAL LP 0.00% of their portfolio | 24.4k $168.0k | Reduced -6.7k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 23.5k $162.3k | Reduced -70.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 22.5k $155.1k | Reduced -8.0k |
| STIFEL FINANCIAL CORP 0.00% of their portfolio | 21.6k $149.0k | Reduced -15.0k |
| Brooklyn Investment Group 0.01% of their portfolio | 19.9k $134.2k | New |
| Aquatic Capital Management LLC 0.00% of their portfolio | 19.8k $136.7k | New |
| Zhang Financial LLC 0.00% of their portfolio | 19.0k $131.4k | Unchanged |
| Squarepoint Ops LLC 0.00% of their portfolio | 19.0k $130.8k | New |
| Walleye Trading LLC 0.00% of their portfolio | 16.4k $113.2k | Added +2.2k |
| Scientech Research LLC 0.07% of their portfolio | 16.0k $110.3k | New |
| CWM, LLC 0.00% of their portfolio | 15.5k $107.0k | Reduced -120 |
| China Universal Asset Management Co., Ltd. 0.01% of their portfolio | 15.4k $105.9k | Reduced -723 |
| OLD NATIONAL BANCORP /IN/ 0.00% of their portfolio | 15.3k $105.3k | Reduced -1.0k |
| ACORN FINANCIAL ADVISORY SERVICES INC /ADV 0.02% of their portfolio | 15.0k $103.5k | Unchanged |
| U.S. Capital Wealth Advisors, LLC 0.00% of their portfolio | 15.0k $103.5k | New |
| Walleye Capital LLC 0.00% of their portfolio | 15.0k $103.3k | Added +7.6k |
| LGT Financial Advisors LLC 0.62% of their portfolio | 14.7k $101.4k | Unchanged |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 14.5k $100.3k | Added +768 |
| LPL Financial LLC 0.00% of their portfolio | 13.9k $96.2k | Added +1.2k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 13.9k $95.6k | New |
| Ethos Financial Group, LLC 0.01% of their portfolio | 13.5k $93.4k | Added +1.2k |
| Magnetar Financial LLC 0.00% of their portfolio | 13.2k $91.0k | New |