CODEXIS INC CDXS
COM · Common Stock · CUSIP 192005106
American protein engineering company
- SectorMaterials
- IndustryIndustrial Organic Chemicals
- HeadquartersRedwood City, CA
- Founded2002
- Websitecodexis.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($87.4k this quarter). Holder counts are more reliable. Shares outstanding: 90.9m as of 2026-03-05, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.63. Options: 3 managers hold calls ($61.6k notional), 0 hold puts (—).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 174 |
| Q4 2022 | 167 |
| Q1 2023 | 149 |
| Q2 2023 | 127 |
| Q3 2023 | 123 |
| Q4 2023 | 120 |
| Q1 2024 | 125 |
| Q2 2024 | 119 |
| Q3 2024 | 117 |
| Q4 2024 | 135 |
| Q1 2025 | 127 |
| Q2 2025 | 121 |
| Q3 2025 | 131 |
| Q4 2025 | 126 |
| Q1 2026 | 135 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 54 | 59 |
| Q3 2024 | 52 | 43 |
| Q4 2024 | 76 | 41 |
| Q1 2025 | 65 | 59 |
| Q2 2025 | 51 | 60 |
| Q3 2025 | 58 | 53 |
| Q4 2025 | 63 | 53 |
| Q1 2026 | 76 | 54 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $19.7k | $0 | 0.00 |
| Q3 2025 | $174.0k | $44.0k | 0.25 |
| Q4 2025 | $95.2k | $326 | 0.00 |
| Q1 2026 | $61.6k | $0 | 0.00 |
Biggest buyers
| UBS Group AG | Added | +1.4m |
| MILLENNIUM MANAGEMENT LLC | Added | +862.9k |
| Aberdeen Group plc | Added | +713.9k |
| JANE STREET GROUP, LLC | Added | +620.0k |
| AQR CAPITAL MANAGEMENT LLC | Added | +543.9k |
| D. E. Shaw & Co., Inc. | Added | +351.6k |
| Diametric Capital, LP | Added | +247.0k |
| TWO SIGMA INVESTMENTS, LP | Added | +202.2k |
| ALGERT GLOBAL LLC | New | +197.4k |
| Private Advisor Group, LLC | Added | +192.4k |
Biggest sellers
| Prescott Group Capital Management, L.L.C. | Sold out | -2.6m |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -538.8k |
| AMERIPRISE FINANCIAL INC | Reduced | -393.1k |
| BlackRock, Inc. | Reduced | -367.0k |
| FEDERATED HERMES, INC. | Sold out | -347.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -241.4k |
| FMR LLC | Reduced | -229.3k |
| CITADEL ADVISORS LLC | Reduced | -211.8k |
| Atom Investors LP | Sold out | -184.7k |
| STIFEL FINANCIAL CORP | Sold out | -177.8k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $46.8k28.7k shares |
| SIMPLEX TRADING, LLC | Added | $8.6k5.3k shares |
| GROUP ONE TRADING LLC | Reduced | $6.2k3.8k shares |
Biggest puts
| None |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Opaleye Management Inc. 13G · passive investor no change · filed 2026-05-05 | 7.5% |
| Aberdeen Group plc 13G · institution -1.4 pts · filed 2026-07-20 | 7.5% |
| Telemark Asset Management, LLC 13G · passive investor new · filed 2026-07-29 | 7.3% |
| BlackRock, Inc. 13G · institution filed 2025-04-24 | 7.2% |
| LYTTON LAURENCE W 13G · passive investor +0.2 pts · filed 2026-08-13 | 5.2% |
| INTEGRATED CORE STRATEGIES (US) LLC 13G · passive investor new · filed 2026-04-14 | 5.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26), Casdin Capital, LLC (0.0%, 2025-11-14)
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 4 | $32.1k | — |
| Q1 2026 | 0 | — | 3 | $22.9k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-02-24 | Lutz Stefan Chief Scientific Officer | Sold | $6.6k5.9k shares |
| 2026-02-06 | MOORE ALISON President and CEO, director | Sold | $5.0k3.8k shares |
| 2026-02-06 | Erbez Georgia Officer | Sold | $5.0k3.8k shares |
| 2026-02-06 | Lutz Stefan Chief Scientific Officer | Sold | $3.3k2.5k shares |
| 2026-01-07 | Lutz Stefan CSO | Sold | $8.0k4.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| Aberdeen Group plc 0.02% of their portfolio | 8.7m $14.1m | Added +713.9k |
| BlackRock, Inc. 0.00% of their portfolio | 7.0m $11.5m | Reduced -367.0k |
| Opaleye Management Inc. 1.46% of their portfolio | 6.8m $11.1m | Reduced -4.7k |
| Nantahala Capital Management, LLC 0.42% of their portfolio | 4.1m $6.7m | Added +133.4k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 4.0m $6.5m | Added +862.9k |
| Telemark Asset Management, LLC 0.58% of their portfolio | 3.8m $6.3m | Unchanged |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 3.7m $6.0m | First filing |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 3.4m $5.5m | Reduced -393.1k |
| UBS Group AG 0.00% of their portfolio | 2.2m $3.6m | Added +1.4m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.9m $3.1m | Reduced -140.7k |
| STATE STREET CORP 0.00% of their portfolio | 1.7m $2.7m | Added +63.4k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.01% of their portfolio | 1.1m $1.8m | Reduced -47.2k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 979.8k $1.6m | Added +351.6k |
| Timothy G. Youngquist 2020 Irrevocable Trust 0.78% of their portfolio | 978.1k $1.6m | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 920.0k $1.5m | Added +620.0k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 879.3k $1.4m | First filing |
| Private Advisor Group, LLC 0.01% of their portfolio | 847.0k $1.4m | Added +192.4k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 824.9k $1.3m | Added +106.8k |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 751.2k $1.2m | Added +184.6k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 688.2k $1.1m | Reduced -52.3k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 657.1k $1.1m | Added +11.8k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 608.6k $992.0k | Added +543.9k |
| Post Resch Tallon Group Inc. 0.79% of their portfolio | 571.5k $974.9k | Added +59.7k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 551.0k $898.1k | First filing |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 537.8k $876.7k | Unchanged |
| PERKINS CAPITAL MANAGEMENT INC 0.81% of their portfolio | 527.5k $859.8k | Reduced -2.0k |
| MORGAN STANLEY 0.00% of their portfolio | 472.8k $770.7k | Added +41.7k |
| Stonepine Capital Management, LLC 0.60% of their portfolio | 418.0k $681.3k | Added +161.9k |
| FMR LLC 0.00% of their portfolio | 412.6k $672.5k | Reduced -229.3k |
| Nuveen, LLC 0.00% of their portfolio | 367.4k $598.9k | Added +66.6k |
| Diametric Capital, LP 0.15% of their portfolio | 359.3k $585.6k | Added +247.0k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 287.6k $468.8k | Reduced -211.8k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 284.6k $463.4k | Reduced -121.4k |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 282.4k $460.3k | Reduced -146.5k |
| Potomac Capital Management, Inc. 0.39% of their portfolio | 274.2k $446.9k | Reduced -25.8k |
| PLATINUM INVESTMENT MANAGEMENT LTD 0.11% of their portfolio | 264.5k $431.1k | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 242.2k $394.8k | Reduced -32.7k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 242.0k $394.4k | Added +202.2k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 215.4k $351.0k | Added +98.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 209.6k $341.7k | Added +4.9k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 198.7k $323.9k | Reduced -538.8k |
| ALGERT GLOBAL LLC 0.00% of their portfolio | 197.4k $321.8k | New |
| Invesco Ltd. 0.00% of their portfolio | 180.9k $294.9k | Added +6.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 174.0k $283.5k | Added +104.0k |
| XTX Topco Ltd 0.00% of their portfolio | 167.5k $273.1k | Added +93.0k |
| BARCLAYS PLC 0.00% of their portfolio | 155.1k $252.8k | Reduced -89.8k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 133.7k $217.9k | New |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 125.9k $205.2k | Reduced -25.0k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 123.7k $200.0k | Added +35.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 118.1k $192.6k | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.01% of their portfolio | 116.9k $191.0k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 99.3k $161.9k | Reduced -9.3k |
| STRS OHIO 0.00% of their portfolio | 99.1k $161.5k | Unchanged |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 93.1k $151.7k | Added +41.7k |
| LPL Financial LLC 0.00% of their portfolio | 75.1k $122.3k | Reduced -3.8k |
| Quadrature Capital Ltd 0.00% of their portfolio | 64.2k $104.6k | Added +9.8k |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 63.8k $103.9k | Added +23.9k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 63.6k $104.0k | Added +19.3k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 58.5k $95.3k | Reduced -572 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 56.6k $92.3k | Reduced -65.4k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 54.7k $89.1k | Added +19.9k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 53.2k $86.8k | Reduced -241.4k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 42.4k $69.1k | Added +1.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 41.4k $62.9k | Added +430 |
| CWM, LLC 0.00% of their portfolio | 39.1k $63.7k | Added +37.3k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 36.6k $59.6k | Unchanged |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 36.4k $59.4k | Added +19.3k |
| Krilogy Financial LLC 0.00% of their portfolio | 36.3k $92.1k | Added +6.2k |
| Frec Markets, Inc. 0.01% of their portfolio | 36.3k $59.1k | New |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 35.0k $57.0k | New |
| Cerity Partners LLC 0.00% of their portfolio | 32.9k $53.6k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 32.6k $53.1k | First filing |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 31.5k $51.3k | Reduced -5.8k |
| BLAIR WILLIAM & CO/IL 0.00% of their portfolio | 30.0k $48.9k | Reduced -372 |
| EVERGREEN CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 29.0k $47.3k | Unchanged |
| Capital Advisors, Ltd. LLC 0.01% of their portfolio | 28.9k $47.0k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 27.4k $44.7k | Reduced -5.3k |
| GUGGENHEIM CAPITAL LLC 0.00% of their portfolio | 26.9k $43.9k | Reduced -405 |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 24.2k $39.5k | Reduced -11.2k |
| Mariner, LLC 0.00% of their portfolio | 23.5k $38.3k | New |
| Elmwood Wealth Management, Inc. 0.01% of their portfolio | 21.7k $35.4k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 20.7k $33.7k | Added +23 |
| FNY Investment Advisers, LLC 0.01% of their portfolio | 20.0k $32.0k | New |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 19.4k $31.7k | Unchanged |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 18.9k $34.3k | New |
| Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio | 18.2k $29.6k | New |
| MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio | 17.7k $28.8k | New |
| ProShare Advisors LLC 0.00% of their portfolio | 17.0k $27.7k | Reduced -3.2k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 16.9k $27.5k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 16.0k $26.1k | Added +1.3k |
| Navalign, LLC 0.01% of their portfolio | 15.3k $25.0k | Unchanged |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 14.8k $24.1k | Reduced -27 |
| StoneX Group Inc. 0.00% of their portfolio | 14.1k $23.0k | New |
| Fiduciary Trust Co 0.00% of their portfolio | 13.6k $22.2k | Unchanged |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 13.6k $22.1k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 13.6k $22.1k | Reduced -13.8k |
| Simplicity Wealth,LLC 0.00% of their portfolio | 13.3k $21.7k | New |
| CITIGROUP INC 0.00% of their portfolio | 11.9k $19.4k | Added +6.5k |
| Caerus Investment Advisors, LLC 0.01% of their portfolio | 10.6k $17.2k | New |
| Pallas Capital Advisors LLC 0.00% of their portfolio | 10.3k $16.8k | New |