Vault-13

CLENE INC CLNN

COMMON STOCK · Common Stock · CUSIP 185634102

51 institutional holders +19 vs Q1 2023
30,806,73130.8m shares reported held*
$26.8mreported value*
19 new 7 added 3 reduced 3 sold out net bought ≈ $25.1m (+28.5m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.3m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $0.87. Options: 5 managers hold calls ($120.8k notional), 6 hold puts ($490.2k).

Trends to Q2 2023

Institutional holders

Managers reporting a position, each quarter

0204060Q3 22: 38Q4 22: 36Q1 23: 32Q2 23: 5151Q3 22Q4 22Q1 23Q2 23
Numbers
QuarterHolders
Q3 202238
Q4 202236
Q1 202332
Q2 202351

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
40040Q4 22: 17 bought or addedQ4 22: 17 cut or sold outQ4 22Q1 23: 14 bought or addedQ1 23: 15 cut or sold outQ1 23Q2 23: 26 bought or addedQ2 23: 6 cut or sold outQ2 23
Numbers
QuarterBought or addedCut or sold out
Q4 20221717
Q1 20231415
Q2 2023266

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$10m$20m$30mQ3 22 calls: $3.9mQ3 22 puts: $20.2mQ3 22P/C 5.14Q4 22 calls: $86.3kQ4 22 puts: $637.1kQ4 22P/C 7.38Q1 23 calls: $86.3kQ1 23 puts: $458.3kQ1 23P/C 5.31Q2 23 calls: $120.8kQ2 23 puts: $490.2kQ2 23P/C 4.06
Numbers
QuarterCallsPutsP/C
Q3 2022$3.9m$20.2m5.14
Q4 2022$86.3k$637.1k7.38
Q1 2023$86.3k$458.3k5.31
Q2 2023$120.8k$490.2k4.06

Biggest buyers

AIGH Capital Management LLC New +5,937,500+5.9m
AWM Investment Company, Inc. New +5,000,000+5.0m
Vivo Capital, LLC New +4,520,622+4.5m
ACUTA CAPITAL PARTNERS, LLC New +4,240,846+4.2m
Alyeska Investment Group, L.P. New +1,973,135+2.0m
CITADEL ADVISORS LLC New +1,853,363+1.9m
Worth Venture Partners, LLC New +1,482,593+1.5m
Hudson Bay Capital Management LP New +1,378,600+1.4m
VANGUARD GROUP INC Added +1,079,601+1.1m
SCOGGIN MANAGEMENT LP New +500,000+500.0k

Biggest sellers

TWO SIGMA INVESTMENTS, LP Sold out -72,800-72.8k
TWO SIGMA SECURITIES, LLC Reduced -68,243-68.2k
CONDOR CAPITAL MANAGEMENT Reduced -62,500-62.5k
MILLENNIUM MANAGEMENT LLC Reduced -40,244-40.2k
Pointe Capital Management LLC Sold out -5,200-5.2k
Steward Partners Investment Advisory, LLC Sold out -300-300

Biggest calls

GROUP ONE TRADING LLC Added $55.7k63.3k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $35.2k40.0k shares
CITADEL ADVISORS LLC Reduced $17.9k20.4k shares
SIMPLEX TRADING, LLC Added $12.0k14.1k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

SIMPLEX TRADING, LLC Added $149.0k169.6k shares
CITADEL ADVISORS LLC Added $124.1k141.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $101.2k115.0k shares
CVI Holdings, LLC Unchanged $97.9k111.2k shares
GROUP ONE TRADING LLC Added $18.0k20.5k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Vivo Opportunity Fund Holdings, L.P. 13G · passive investor filed 2026-05-12 10.0% 1.9m 2026-05-12
4LIFE RESEARCH LLC 13G · passive investor filed 2025-02-14 6.5% 555.3k 2025-02-14

Insider purchases and sales in Q2 2023

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
505Q3 21: 0 buyingQ3 21: 0 sellingQ4 21: 1 buyingQ4 21: 0 sellingQ4 21Q1 22: 1 buyingQ1 22: 0 sellingQ2 22: 3 buyingQ2 22: 2 sellingQ2 22Q3 22: 1 buyingQ3 22: 1 sellingQ4 22: 5 buyingQ4 22: 0 sellingQ4 22Q1 23: 0 buyingQ1 23: 0 sellingQ2 23: 5 buyingQ2 23: 0 sellingQ2 23
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20210—0——
Q4 20211$542.2k0——
Q1 20221$634.8k0——
Q2 20223$1.9m2$59.6k—
Q3 20221$183.5k1$110.8k—
Q4 20225$4.8m0——
Q1 20230—0——
Q2 20235$3.5m0——
DateInsiderTradeSharesPrice ValueTheir holding
2023-06-26 Stevens John Henry Director Bought 316,455 $0.80 $253.2k316.5k shares +65%
2023-06-26 Etherington Robert Dee Chief Executive Officer, director · By Trust Bought 25,000 $0.81 $20.2k25.0k shares new
2023-06-16 Ugwumba Chidozie 10% owner · By Symbiosis II, LLC Bought 7,500,000 $0.80 $6.0m7.5m shares +136%
2023-06-16 Mosca Alison Director · By LLC Bought 2,394,375 $0.80 $1.9m2.4m shares +284%
2023-06-16 MATLIN DAVID J Director Bought 1,500,000 $0.80 $1.2m1.5m shares +28%
2023-06-16 Gay Jonathon Director · By LLC Bought 105,625 $0.80 $84.5k105.6k shares new

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 AIGH Capital Management LLC 2.14% of their portfolio BALTIMORE, MD 5,937,5005.9m $5.2m $5.2m 2.14% New
2 AWM Investment Company, Inc. 0.60% of their portfolio NEW YORK, NY 5,000,0005.0m $4.4m $4.4m 0.60% New
3 Vivo Capital, LLC 0.26% of their portfolio Palo Alto, CA 4,520,6224.5m $3.7m $3.7m 0.26% New
4 ACUTA CAPITAL PARTNERS, LLC 2.53% of their portfolio REDWOOD CITY, CA 4,240,8464.2m $3.7m $3.7m 2.53% New
5 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 2,200,3772.2m $1.9m $1.9m 0.00% Added +1.1m +1,079,601
6 Alyeska Investment Group, L.P. 0.01% of their portfolio CHICAGO, IL 1,973,1352.0m $1.7m $1.7m 0.01% New
7 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 1,853,3631.9m $1.6m $1.6m 0.00% New
8 Worth Venture Partners, LLC 0.71% of their portfolio FORT LEE, NJ 1,482,5931.5m $1.3m $1.3m 0.71% New
9 Hudson Bay Capital Management LP 0.01% of their portfolio STAMFORD, CT 1,378,6001.4m $1.2m $1.2m 0.01% New
10 Lunt Capital Management, Inc. 0.24% of their portfolio HOLLADAY, UT 512,863512.9k $451.3k $451.3k 0.24% First filing
11 SCOGGIN MANAGEMENT LP 0.79% of their portfolio NEW YORK, NY 500,000500.0k $439.9k $439.9k 0.79% New
12 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 339,635339.6k $298.8k $298.8k 0.00% Added +333.3k +333,346
13 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 314,554314.6k $276.8k $276.8k 0.00% Unchanged
14 Laird Norton Wetherby Trust Company, LLC 0.03% of their portfolio Seattle, WA 268,581268.6k $236.3k $236.3k 0.03% Unchanged
15 SILVERARC CAPITAL MANAGEMENT, LLC 0.07% of their portfolio BOSTON, MA 250,000250.0k $220.0k $220.0k 0.07% New
16 Soltis Investment Advisors LLC 0.02% of their portfolio ST. GEORGE, UT 218,920218.9k $192.6k $192.6k 0.02% Unchanged
17 BlackRock Inc. 0.00% of their portfolio New York, NY 193,996194.0k $170.7k $170.7k 0.00% Added +6.9k +6,885
18 Kepos Capital LP 0.03% of their portfolio NEW YORK, NY 170,000170.0k $150.0k $150.0k 0.03% First filing
19 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 128,046128.0k $112.7k $112.7k 0.00% Unchanged
20 CONDOR CAPITAL MANAGEMENT 0.01% of their portfolio MARTINSVILLE, NJ 103,336103.3k $90.4k $90.4k 0.01% Reduced -62.5k -62,500
21 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio HOUSTON, TX 100,774100.8k $88.7k $88.7k 0.00% Unchanged
22 PARTNERS CAPITAL INVESTMENT GROUP, LLP 0.00% of their portfolio BOSTON, MA 67,85567.9k $59.7k $59.7k 0.00% Unchanged
23 AE Wealth Management LLC 0.00% of their portfolio TOPEKA, KS 55,92855.9k $49.2k $49.2k 0.00% New
24 Impact Partnership Wealth, LLC 0.02% of their portfolio MARIETTA, GA 55,92855.9k $49.2k $49.2k 0.02% First filing
25 Arax Advisory Partners 0.01% of their portfolio NEW YORK, NY 55,25055.2k $48.6k $48.6k 0.01% Unchanged
26 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 49,22149.2k $43.0k $43.0k 0.00% Added +5.2k +5,248
27 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 44,77044.8k $39.4k $39.4k 0.00% Unchanged
28 CVI Holdings, LLC 0.04% of their portfolio WILMINGTON, DE 40,71940.7k $35.8k $35.8k 0.04% New
29 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 40,46640.5k $35.6k $35.6k 0.00% New
30 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 25,69225.7k $22.6k $22.6k 0.00% Unchanged
31 Veritable, L.P. 0.00% of their portfolio Newtown Square, PA 25,23025.2k $22.2k $22.2k 0.00% Unchanged
32 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 22,02722.0k $19.4k $19.4k 0.00% Added +20.5k +20,499
33 TWO SIGMA SECURITIES, LLC 0.00% of their portfolio NEW YORK, NY 21,26621.3k $18.7k $18.7k 0.00% Reduced -68.2k -68,243
34 LPL Financial LLC 0.00% of their portfolio FORT MILL, SC 19,60719.6k $17.3k $17.3k 0.00% New
35 Pallas Capital Advisors LLC 0.00% of their portfolio BRAINTREE, MA 17,34117.3k $14.1k $14.1k 0.00% Unchanged
36 Belpointe Asset Management LLC 0.00% of their portfolio RENO, NV 14,90014.9k $13.1k $13.1k 0.00% New
37 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 14,84414.8k $13.1k $13.1k 0.00% Added +4.4k +4,397
38 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 11,22811.2k $9.9k $9.9k 0.00% Reduced -40.2k -40,244
39 GROUP ONE TRADING LLC 0.00% of their portfolio CHICAGO, IL 5,7385.7k $5.0k $5.0k 0.00% New
40 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 5,0005.0k $4.4k $4.4k 0.00% Unchanged
41 Cutler Group LLC / CA 0.00% of their portfolio SAN FRANCISCO, CA 3,9003.9k $3.0k $3.0k 0.00% Unchanged
42 WASHINGTON TRUST Co 0.00% of their portfolio WESTERLY, RI 2,0002.0k $1.8k $1.8k 0.00% Unchanged
43 IFP Advisors, Inc 0.00% of their portfolio TAMPA, FL 800800 $4.0k $4.0k 0.00% New
44 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 596596 $1.0k $1.0k 0.00% New
45 US BANCORP \DE\ 0.00% of their portfolio MINNEAPOLIS, MN 400400 $352 $352 0.00% Unchanged
46 HARBOUR INVESTMENTS, INC. 0.00% of their portfolio MADISON, WI 275275 $242 $242 0.00% New
47 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 237237 $209 $209 0.00% Added +23 +23
48 WOLVERINE ASSET MANAGEMENT LLC 0.00% of their portfolio CHICAGO, IL 181181 $159 $159 0.00% Unchanged
49 UBS Group AG 0.00% of their portfolio ZURICH, V8 169169 $149 $149 0.00% Unchanged
50 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 1515 $13 $13 0.00% Unchanged
51 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged