Vault-13

CLENE INC CLNN

COMMON STOCK · Common Stock · CUSIP 185634102

36 institutional holders -2 vs Q3 2022
3,081,7183.1m shares reported held*
$3.1mreported value*
9 new 8 added 7 reduced 10 sold out net sold ≈ $1.1m (-1.1m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $1.00. Options: 6 managers hold calls ($86.3k notional), 8 hold puts ($637.1k).

Trends to Q4 2022

Institutional holders

Managers reporting a position, each quarter

02040Q3 22: 38Q4 22: 3636Q3 22Q4 22
Numbers
QuarterHolders
Q3 202238
Q4 202236

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$10m$20m$30mQ3 22 calls: $3.9mQ3 22 puts: $20.2mQ3 22P/C 5.14Q4 22 calls: $86.3kQ4 22 puts: $637.1kQ4 22P/C 7.38
Numbers
QuarterCallsPutsP/C
Q3 2022$3.9m$20.2m5.14
Q4 2022$86.3k$637.1k7.38

Biggest buyers

GROUP ONE TRADING LLC New +126,340+126.3k
Atom Investors LP New +123,051+123.1k
BRIDGEWAY CAPITAL MANAGEMENT, LLC New +100,774+100.8k
Belvedere Trading LLC New +27,295+27.3k
JANE STREET GROUP, LLC New +23,099+23.1k
SUSQUEHANNA INTERNATIONAL GROUP, LLP New +13,000+13.0k
GEODE CAPITAL MANAGEMENT, LLC Added +9,614+9.6k
FNY Investment Advisers, LLC New +5,200+5.2k
MORGAN STANLEY Added +3,399+3.4k
UBS Group AG Added +3,230+3.2k

Biggest sellers

TANG CAPITAL MANAGEMENT LLC Sold out -1,100,000-1.1m
MILLENNIUM MANAGEMENT LLC Reduced -92,947-92.9k
Caption Management, LLC Sold out -81,718-81.7k
Kepos Capital LP Reduced -55,573-55.6k
ROYAL BANK OF CANADA Sold out -52,017-52.0k
SIMPLEX TRADING, LLC Reduced -40,125-40.1k
CITADEL ADVISORS LLC Reduced -33,018-33.0k
OPPENHEIMER & CO INC Sold out -29,526-29.5k
TWO SIGMA INVESTMENTS, LP Reduced -21,429-21.4k
Qube Research & Technologies Ltd Sold out -20,749-20.7k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $31.2k31.2k shares
CITADEL ADVISORS LLC Reduced $23.5k23.5k shares
GROUP ONE TRADING LLC Reduced $17.5k17.5k shares
SIMPLEX TRADING, LLC Reduced $11.0k11.7k shares
Belvedere Trading LLC New $3.1k3.1k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $265.0k265.0k shares
SIMPLEX TRADING, LLC Reduced $208.0k208.7k shares
GROUP ONE TRADING LLC Reduced $95.3k95.3k shares
Belvedere Trading LLC New $36.1k36.1k shares
CITADEL ADVISORS LLC Reduced $31.7k31.7k shares
Cutler Group LLC / CA Reduced $1.0k1.4k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares
FNY Investment Advisers, LLC Reduced $046 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Vivo Opportunity Fund Holdings, L.P. 13G · passive investor filed 2026-05-12 10.0% 1.9m 2026-05-12
4LIFE RESEARCH LLC 13G · passive investor filed 2025-02-14 6.5% 555.3k 2025-02-14

Insider purchases and sales in Q4 2022

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
505Q1 21: 0 buyingQ1 21: 0 sellingQ2 21: 0 buyingQ2 21: 0 sellingQ2 21Q3 21: 0 buyingQ3 21: 0 sellingQ4 21: 1 buyingQ4 21: 0 sellingQ4 21Q1 22: 1 buyingQ1 22: 0 sellingQ2 22: 3 buyingQ2 22: 2 sellingQ2 22Q3 22: 1 buyingQ3 22: 1 sellingQ4 22: 5 buyingQ4 22: 0 sellingQ4 22
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q1 20210—0——
Q2 20210—0——
Q3 20210—0——
Q4 20211$542.2k0——
Q1 20221$634.8k0——
Q2 20223$1.9m2$59.6k—
Q3 20221$183.5k1$110.8k—
Q4 20225$4.8m0——
DateInsiderTradeSharesPrice ValueTheir holding
2022-11-02 MATLIN DAVID J Director Bought 2,871,287 $1.01 $2.9m2.9m shares +118%
2022-11-02 Ugwumba Chidozie Director · By Symbiosis II, LLC Bought 990,099 $1.01 $1,000.0k990.1k shares +22%
2022-11-02 Gay Jonathon Director · By LLC Bought 990,099 $1.01 $1,000.0k990.1k shares +85%
2022-11-02 Mosca Alison Director · By LLC Bought 792,079 $1.01 $800.0k792.1k shares +1526%
2022-11-02 Stevens John Henry Director Bought 148,515 $1.01 $150.0k148.5k shares +44%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q4 2022

#ManagerLocationShares Value% of their portfolioChangeShares change
1 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 932,058932.1k $932.1k $932.1k 0.00% Added +445 +445
2 Kepos Capital LP 0.05% of their portfolio NEW YORK, NY 344,427344.4k $344.0k $344.0k 0.05% Reduced -55.6k -55,573
3 Laird Norton Wetherby Trust Company, LLC 0.04% of their portfolio Seattle, WA 268,581268.6k $268.6k $268.6k 0.04% Unchanged
4 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 230,805230.8k $230.0k $230.0k 0.00% Added +9.6k +9,614
5 Soltis Investment Advisors LLC 0.03% of their portfolio ST. GEORGE, UT 218,920218.9k $218.9k $218.9k 0.03% Unchanged
6 BlackRock Inc. 0.00% of their portfolio New York, NY 185,245185.2k $185.2k $185.2k 0.00% Added +1.2k +1,244
7 GROUP ONE TRADING LLC 0.00% of their portfolio CHICAGO, IL 126,340126.3k $126.3k $126.3k 0.00% New
8 Atom Investors LP 0.06% of their portfolio AUSTIN, TX 123,051123.1k $123.1k $123.1k 0.06% New
9 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 117,137117.1k $117.0k $117.0k 0.00% Reduced -92.9k -92,947
10 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio HOUSTON, TX 100,774100.8k $100.8k $100.8k 0.00% New
11 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 92,29092.3k $92.0k $92.0k 0.00% Reduced -40.1k -40,125
12 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 68,04668.0k $68.0k $68.0k 0.00% Unchanged
13 Arax Advisory Partners 0.01% of their portfolio NEW YORK, NY 55,25055.2k $55.2k $55.2k 0.01% Unchanged
14 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 37,17237.2k $37.2k $37.2k 0.00% Unchanged
15 Belvedere Trading LLC 0.02% of their portfolio CHICAGO, IL 27,29527.3k $27.3k $27.3k 0.02% New
16 Veritable, L.P. 0.00% of their portfolio Newtown Square, PA 25,23025.2k $25.2k $25.2k 0.00% Unchanged
17 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 23,09923.1k $23.1k $23.1k 0.00% New
18 Pallas Capital Advisors LLC 0.00% of their portfolio BRAINTREE, MA 17,34117.3k $25.8k $25.8k 0.00% Unchanged
19 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 16,74416.7k $16.7k $16.7k 0.00% Added +3.4k +3,399
20 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 13,00013.0k $13.0k $13.0k 0.00% New
21 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 11,97012.0k $12.0k $12.0k 0.00% Reduced -21.4k -21,429
22 UBS Group AG 0.00% of their portfolio ZURICH, V8 9,7129.7k $9.7k $9.7k 0.00% Added +3.2k +3,230
23 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 9,3369.3k $9.0k $9.0k 0.00% Reduced -5.0k -5,042
24 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 6,8786.9k $6.9k $6.9k 0.00% Added +30 +30
25 FNY Investment Advisers, LLC 0.01% of their portfolio NEW YORK, NY 5,2005.2k $5.0k $5.0k 0.01% New
26 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 5,0005.0k $5.0k $5.0k 0.00% Unchanged
27 Cutler Group LLC / CA 0.00% of their portfolio SAN FRANCISCO, CA 4,2004.2k $4.0k $4.0k 0.00% Added +2.6k +2,600
28 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 3,4513.5k $3.5k $3.5k 0.00% Reduced -33.0k -33,018
29 WASHINGTON TRUST Co 0.00% of their portfolio WESTERLY, RI 2,0002.0k $2.0k $2.0k 0.00% Unchanged
30 US BANCORP \DE\ 0.00% of their portfolio MINNEAPOLIS, MN 400400 $400 $400 0.00% Reduced -440 -440
31 Steward Partners Investment Advisory, LLC 0.00% of their portfolio STAMFORD, CT 300300 $300 $300 0.00% New
32 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 211211 $211 $211 0.00% Added +77 +77
33 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 140140 $140 $140 0.00% First filing
34 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 100100 $100 $100 0.00% New
35 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 1515 $0 $0 0.00% Unchanged
36 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged