PELTHOS THERAPEUTICS INC PTHS
COM SHS · Common Stock · CUSIP 171126204
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersDurham, NC
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 3.8m as of 2026-08-10, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $28.26.
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2025 | 14 |
| Q4 2025 | 15 |
| Q1 2026 | 17 |
| Q2 2026 | 24 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2025 | 14 | 3 |
| Q1 2026 | 11 | 4 |
| Q2 2026 | 17 | 5 |
Biggest buyers
| AIGH Capital Management LLC | New | +329.1k |
| CANTOR FITZGERALD, L. P. | Added | +34.8k |
| WEXFORD CAPITAL LP | New | +22.4k |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | +20.1k |
| CITADEL ADVISORS LLC | New | +15.0k |
| 1492 Capital Management LLC | New | +10.4k |
| STATE STREET CORP | New | +9.8k |
| Murchinson Ltd. | Added | +8.0k |
| BlackRock, Inc. | New | +5.3k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +4.0k |
Biggest sellers
| J. Goldman & Co LP | Reduced | -12.3k |
| Steward Partners Investment Advisory, LLC | Sold out | -1.9k |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | -640 |
| Aspect Partners, LLC | Sold out | -16 |
| CITIGROUP INC | Sold out | -1 |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
LIGAND PHARMACEUTICALS INC
13D · may seek influence
no change · filed 2025-11-10
Stated purposeItem 4 of the Schedule 13D is hereby supplemented as follows: Convertible Note Financing On November 6, 2025, Ligand entered into the Convertible Note Purchase Agreement with the Issuer and the other investors party thereto, pursuant to which the Issuer issued and sold to Ligand $9.0 million aggregate principal amount of Convertible Notes. The Convertible Notes Issuance closed on November 6, 2025. The Convertible Notes mature 24 months from the date of issuance. The Convertible Notes bear interest at a rate of 8.5% per annum, payable quarterly in arrears, which may, at the Issuer's option, be paid in cash or capitalized and added to principal. The Convertible Notes rank senior to current and future indebtedness of the Issuer and its subsidiaries, other than certain senior indebtednes… Full filing |
49.9% |
| 3i, LP 13G · passive investor no change · filed 2026-05-07 | 9.9% |
| Murchinson Ltd. 13G · institution new · filed 2025-11-14 | 9.1% |
Friedberg Ezra M
13D · may seek influence
filed 2025-07-03
Stated purpose"Item 4: Purpose of Transaction" is not being amended by this Amendment No. 1. Full filing |
8.3% |
| Ikarian Capital, LLC 13G · institution -0.7 pts · filed 2026-05-15 | 7.7% |
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 1 | $280.3k | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 1 | $999.8k | 5 | $105.1k | $64.8k |
| Q3 2026 | 0 | — | 3 | $55.9k | $55.9k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-07-02 | Greenleaf Peter Director | Sold plan | $20.8k797 shares |
| 2026-07-02 | Pauls Matthew Director | Sold plan | $20.6k786 shares |
| 2026-07-02 | Friedberg Ezra M Director | Sold plan | $14.6k558 shares |
| 2026-06-15 | Friedberg Ezra M Director | Sold plan | $7.7k283 shares |
| 2026-06-11 | Davis Todd C Director | Bought | $999.8k35.9k shares |
| 2026-05-22 | Francis Knuettel II CFO, Treas & Secty | Sold | $40.3k1.5k shares |
| 2026-04-02 | Greenleaf Peter Director | Sold plan | $16.7k797 shares |
| 2026-04-02 | Pauls Matthew Director | Sold plan | $16.4k786 shares |
| 2026-04-02 | Malamut Richard Director | Sold plan | $12.3k590 shares |
| 2026-04-02 | Friedberg Ezra M Director | Sold plan | $11.7k558 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| AIGH Capital Management LLC 0.84% of their portfolio | 329.1k $9.3m | New |
| Murchinson Ltd. 4.15% of their portfolio | 304.3k $8.6m | Added +8.0k |
| Ikarian Capital, LLC 1.19% of their portfolio | 256.6k $7.3m | Unchanged |
| BOOTHBAY FUND MANAGEMENT, LLC 0.05% of their portfolio | 102.0k $2.9m | Added +20.1k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 97.1k $2.7m | Added +4.0k |
| CANTOR FITZGERALD, L. P. 0.02% of their portfolio | 76.2k $2.2m | Added +34.8k |
| J. Goldman & Co LP 0.04% of their portfolio | 38.1k $1.1m | Reduced -12.3k |
| DIADEMA PARTNERS LP 0.25% of their portfolio | 24.8k $700.1k | Unchanged |
| WEXFORD CAPITAL LP 0.09% of their portfolio | 22.4k $632.0k | New |
| Knott David M Jr 0.33% of their portfolio | 22.1k $623.8k | Added +1.0k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 15.0k $425.2k | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 14.7k $414.0k | Reduced -640 |
| Pale Fire Capital SE 0.03% of their portfolio | 12.9k $365.1k | Unchanged |
| 1492 Capital Management LLC 0.09% of their portfolio | 10.4k $293.3k | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 9.9k $279.0k | Added +56 |
| STATE STREET CORP 0.00% of their portfolio | 9.8k $276.9k | New |
| Persistent Asset Partners Ltd 0.05% of their portfolio | 6.0k $169.8k | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 5.3k $150.5k | New |
| UBS Group AG 0.00% of their portfolio | 2.2k $62.7k | Added +1.5k |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 2.2k $61.0k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 205 $5.8k | New |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 40 $1.1k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 20 $565 | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 6 $0 | New |