CHARLES RIV LABS INTL INC CRL
COM · Common Stock · CUSIP 159864107 · ISIN US1598641074
Major US biomedical company
- SectorHealth care
- IndustryServices-Commercial Physical & Biological Research
- HeadquartersWilmington, MA
- Founded1947
- Websitecriver.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($17.5m this quarter). Holder counts are more reliable. Shares outstanding: 49.1m as of 2025-04-26, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $150.38. Options: 12 managers hold calls ($105.6m notional), 11 hold puts ($121.9m).
Trends to Q1 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 584 |
| Q4 2022 | 629 |
| Q1 2023 | 623 |
| Q2 2023 | 613 |
| Q3 2023 | 623 |
| Q4 2023 | 634 |
| Q1 2024 | 675 |
| Q2 2024 | 666 |
| Q3 2024 | 629 |
| Q4 2024 | 637 |
| Q1 2025 | 564 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2023 | 309 | 278 |
| Q3 2023 | 303 | 281 |
| Q4 2023 | 265 | 328 |
| Q1 2024 | 341 | 274 |
| Q2 2024 | 330 | 316 |
| Q3 2024 | 263 | 370 |
| Q4 2024 | 248 | 362 |
| Q1 2025 | 246 | 374 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2024 | $54.2m | $48.8m | 0.90 |
| Q3 2024 | $59.0m | $94.8m | 1.61 |
| Q4 2024 | $28.5m | $44.2m | 1.55 |
| Q1 2025 | $105.6m | $121.9m | 1.15 |
Biggest buyers
| UBS Group AG | Added | +2.1m |
| GOLDMAN SACHS GROUP INC | Added | +800.8k |
| Assenagon Asset Management S.A. | Added | +538.8k |
| ROYAL BANK OF CANADA | Added | +472.6k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | New | +353.6k |
| AMERIPRISE FINANCIAL INC | Added | +321.8k |
| JPMORGAN CHASE & CO | Added | +296.2k |
| NOMURA HOLDINGS INC | Added | +293.8k |
| NEUBERGER BERMAN GROUP LLC | Added | +281.8k |
| SG Americas Securities, LLC | Added | +265.6k |
Biggest sellers
| MACKENZIE FINANCIAL CORP | Reduced | -1.9m |
| Meritage Group LP | Sold out | -1.1m |
| Southpoint Capital Advisors LP | Sold out | -600.0k |
| BlackRock, Inc. | Reduced | -561.3k |
| M.D. Sass, LLC | Sold out | -391.8k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -297.7k |
| STATE STREET CORP | Reduced | -278.8k |
| Empower Advisory Group, LLC | Reduced | -270.4k |
| Alyeska Investment Group, L.P. | Sold out | -200.3k |
| EMINENCE CAPITAL, LP | Reduced | -192.0k |
Biggest calls
| NOMURA HOLDINGS INC | New | $90.3m600.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $5.2m34.8k shares |
| CITADEL ADVISORS LLC | Reduced | $5.2m34.3k shares |
| Walleye Trading LLC | Added | $1.2m7.7k shares |
| TUDOR INVESTMENT CORP ET AL | Added | $1.0m6.7k shares |
| WOLVERINE TRADING, LLC | Added | $684.4k4.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $587.0k3.9k shares |
| Cubist Systematic Strategies, LLC | Reduced | $526.8k3.5k shares |
| Walleye Capital LLC | Reduced | $376.3k2.5k shares |
| GROUP ONE TRADING LLC | New | $301.0k2.0k shares |
Biggest puts
| NOMURA HOLDINGS INC | New | $90.3m600.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $16.3m108.6k shares |
| CITADEL ADVISORS LLC | Reduced | $6.9m45.7k shares |
| JANE STREET GROUP, LLC | Reduced | $4.3m28.4k shares |
| WOLVERINE TRADING, LLC | Reduced | $2.3m14.6k shares |
| Cubist Systematic Strategies, LLC | Added | $617.1k4.1k shares |
| Walleye Trading LLC | Reduced | $421.5k2.8k shares |
| TUDOR INVESTMENT CORP ET AL | Reduced | $301.0k2.0k shares |
| D. E. Shaw & Co., Inc. | Unchanged | $240.8k1.6k shares |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | New | $135.5k900 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| FMR LLC 13G · institution +1.4 pts · filed 2026-09-08 | 10.2% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-29 | 7.4% |
| BlackRock, Inc. 13G · institution filed 2025-04-17 | 6.9% |
| Invesco Ltd. 13G · institution +1.3 pts · filed 2026-08-13 | 6.2% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26; now reported by VANGUARD CAPITAL MANAGEMENT LLC), WELLINGTON MANAGEMENT GROUP LLP (3.6%, 2026-02-10), NOMURA HOLDINGS INC (1.6%, 2025-11-14)
Insider purchases and sales in Q1 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2023 | 0 | — | 2 | $306.5k | $55.7k |
| Q3 2023 | 1 | $198.8k | 3 | $1.7m | — |
| Q4 2023 | 2 | $1.2m | 2 | $3.2m | $1.2m |
| Q1 2024 | 0 | — | 5 | $5.8m | $1.4m |
| Q2 2024 | 0 | — | 2 | $374.2k | $78.2k |
| Q3 2024 | 0 | — | 2 | $6.6m | $6.2m |
| Q4 2024 | 0 | — | 1 | $1.6m | — |
| Q1 2025 | 2 | $1.3m | 1 | $715.0k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-02-20 | FOSTER JAMES C Chairman, President and CEO, director | Bought | $1.0m6.1k shares |
| 2025-02-20 | LaPlume Joseph W EVP, Corp Strategy & Develop | Sold | $715.0k4.4k shares |
| 2025-02-20 | Girshick Birgit Corporate Executive VP & COO | Bought | $249.2k1.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2025
| Manager | Shares | Change |
|---|---|---|
| VANGUARD GROUP INC 0.02% of their portfolio | 6.1m $919.0m | Reduced -53.4k |
| WELLINGTON MANAGEMENT GROUP LLP 0.12% of their portfolio | 4.3m $645.0m | Added +208.6k |
| BlackRock, Inc. 0.01% of their portfolio | 3.7m $552.5m | Reduced -561.3k |
| UBS Group AG 0.08% of their portfolio | 2.4m $360.0m | Added +2.1m |
| KAYNE ANDERSON RUDNICK INVESTMENT MANAGEMENT LLC 0.72% of their portfolio | 2.0m $293.6m | Added +144.7k |
| STATE STREET CORP 0.01% of their portfolio | 1.9m $286.4m | Reduced -278.8k |
| Allspring Global Investments Holdings, LLC 0.45% of their portfolio | 1.8m $259.1m | Reduced -33.4k |
| GEODE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 1.3m $189.9m | Added +30.5k |
| Impactive Capital LP 8.34% of their portfolio | 1.2m $182.4m | Added +9.2k |
| Invesco Ltd. 0.03% of their portfolio | 1.1m $166.8m | Added +74.2k |
| ARIEL INVESTMENTS, LLC 1.95% of their portfolio | 1.1m $165.7m | Added +33.4k |
| EARNEST PARTNERS LLC 0.72% of their portfolio | 1.0m $151.2m | Added +22.5k |
| MACKENZIE FINANCIAL CORP 0.21% of their portfolio | 1.0m $151.0m | Reduced -1.9m |
| GOLDMAN SACHS GROUP INC 0.03% of their portfolio | 997.5k $150.1m | Added +800.8k |
| DIMENSIONAL FUND ADVISORS LP 0.03% of their portfolio | 862.3k $129.8m | Added +198.8k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 794.0k $119.5m | Reduced -28.8k |
| D1 Capital Partners L.P. 1.79% of their portfolio | 777.5k $117.0m | Reduced -158.3k |
| JPMORGAN CHASE & CO 0.01% of their portfolio | 758.4k $114.2m | Added +296.2k |
| Clearbridge Investments, LLC 0.09% of their portfolio | 688.6k $103.6m | Reduced -86.6k |
| SEI INVESTMENTS CO 0.13% of their portfolio | 668.2k $100.6m | Reduced -5.7k |
| ROYAL BANK OF CANADA 0.02% of their portfolio | 627.7k $94.5m | Added +472.6k |
| NOMURA HOLDINGS INC 0.48% of their portfolio | 601.6k $90.6m | Added +293.8k |
| NEUBERGER BERMAN GROUP LLC 0.07% of their portfolio | 591.0k $89.1m | Added +281.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.02% of their portfolio | 577.3k $86.9m | Added +24.3k |
| Assenagon Asset Management S.A. 0.15% of their portfolio | 570.1k $85.8m | Added +538.8k |
| AMERIPRISE FINANCIAL INC 0.02% of their portfolio | 544.8k $82.0m | Added +321.8k |
| FRANKLIN RESOURCES INC 0.02% of their portfolio | 497.8k $74.9m | Reduced -150.0k |
| NORTHERN TRUST CORP 0.01% of their portfolio | 492.5k $74.1m | Added +252 |
| WELLS FARGO & COMPANY/MN 0.02% of their portfolio | 468.0k $70.4m | Reduced -15.5k |
| MORGAN STANLEY 0.00% of their portfolio | 459.0k $69.1m | Reduced -19.5k |
| Van Berkom & Associates Inc. 2.16% of their portfolio | 447.1k $67.3m | Added +59.1k |
| NORGES BANK 0.01% of their portfolio | 437.8k $65.9m | Reduced -97.9k |
| EMINENCE CAPITAL, LP 1.10% of their portfolio | 435.5k $65.5m | Reduced -192.0k |
| COOKE & BIELER LP 0.63% of their portfolio | 419.6k $63.2m | Reduced -7.1k |
| DEUTSCHE BANK AG\ 0.02% of their portfolio | 411.4k $61.9m | Added +178.9k |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.04% of their portfolio | 353.6k $53.2m | New |
| Bank of New York Mellon Corp 0.01% of their portfolio | 345.3k $52.0m | Reduced -123.3k |
| CITADEL ADVISORS LLC 0.04% of their portfolio | 282.0k $42.4m | Added +111.4k |
| PRIMECAP MANAGEMENT CO/CA/ 0.03% of their portfolio | 272.9k $41.1m | Reduced -90 |
| SG Americas Securities, LLC 0.14% of their portfolio | 267.2k $40.2m | Added +265.6k |
| Fisher Asset Management, LLC 0.02% of their portfolio | 255.2k $38.4m | Added +22.9k |
| Premier Fund Managers Ltd 1.45% of their portfolio | 250.1k $38.9m | Added +99 |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 246.6k $37.1m | Reduced -51.6k |
| CITIGROUP INC 0.03% of their portfolio | 234.5k $35.3m | Reduced -10.2k |
| RAYMOND JAMES FINANCIAL INC 0.01% of their portfolio | 223.0k $33.6m | Reduced -8.8k |
| RIVERBRIDGE PARTNERS LLC 0.54% of their portfolio | 222.7k $33.5m | Reduced -16.7k |
| ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio | 221.3k $33.3m | Reduced -23.0k |
| Boston Trust Walden Corp 0.23% of their portfolio | 205.4k $30.9m | Added +919 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.03% of their portfolio | 190.3k $28.6m | Reduced -4.4k |
| VICTORY CAPITAL MANAGEMENT INC 0.03% of their portfolio | 177.5k $26.7m | Reduced -148.4k |
| SNYDER CAPITAL MANAGEMENT L P 0.57% of their portfolio | 174.3k $26.2m | Reduced -3.7k |
| TWO SIGMA INVESTMENTS, LP 0.05% of their portfolio | 163.3k $24.6m | Added +84.5k |
| Gotham Asset Management, LLC 0.19% of their portfolio | 154.8k $23.3m | Added +31.1k |
| LAKEWOOD CAPITAL MANAGEMENT, LP 1.88% of their portfolio | 140.2k $21.1m | Added +28.5k |
| JANE STREET GROUP, LLC 0.04% of their portfolio | 137.4k $20.7m | Added +101.1k |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.08% of their portfolio | 136.7k $20.6m | Reduced -19.8k |
| MOUNTAIN PACIFIC INVESTMENT ADVISERS LLC 1.53% of their portfolio | 136.5k $20.5m | Reduced -2.2k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.03% of their portfolio | 131.8k $19.8m | Added +18.9k |
| NORRIS PERNE & FRENCH LLP/MI 1.46% of their portfolio | 129.1k $19.4m | Added +3.0k |
| FIRST TRUST ADVISORS LP 0.02% of their portfolio | 127.4k $19.2m | Added +11.9k |
| Nuveen, LLC 0.01% of their portfolio | 123.2k $18.5m | First filing |
| Man Group plc 0.05% of their portfolio | 121.1k $18.2m | Added +38.7k |
| BARCLAYS PLC 0.01% of their portfolio | 119.7k $18.0m | Reduced -7.0k |
| Quantinno Capital Management LP 0.12% of their portfolio | 117.8k $17.7m | Added +80.9k |
| DF DENT & CO INC 0.23% of their portfolio | 115.0k $17.3m | Added +2.5k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.02% of their portfolio | 105.3k $15.8m | Added +102.0k |
| Aristotle Capital Boston, LLC 0.79% of their portfolio | 104.5k $15.7m | Reduced -25.7k |
| FMR LLC 0.00% of their portfolio | 101.7k $15.3m | Reduced -40.4k |
| Swiss National Bank 0.01% of their portfolio | 99.1k $14.9m | Reduced -46.8k |
| CONFLUENCE INVESTMENT MANAGEMENT LLC 0.21% of their portfolio | 96.5k $14.5m | Added +3.5k |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 94.6k $14.2m | First filing |
| Legal & General Group Plc 0.00% of their portfolio | 94.6k $14.2m | Reduced -143.3k |
| Laurus Global Equity Management Inc. 9.06% of their portfolio | 90.2k $13.6m | Added +11.0k |
| GW&K Investment Management, LLC 0.12% of their portfolio | 88.4k $13.3m | Added +25.7k |
| RHUMBLINE ADVISERS 0.01% of their portfolio | 86.7k $13.1m | Added +3.4k |
| STIFEL FINANCIAL CORP 0.01% of their portfolio | 85.2k $12.8m | Reduced -4.9k |
| NATIXIS ADVISORS, LLC 0.02% of their portfolio | 85.0k $12.8m | Added +6.6k |
| Caisse de depot et placement du Quebec 0.03% of their portfolio | 85.0k $12.8m | New |
| LORD, ABBETT & CO. LLC 0.05% of their portfolio | 84.4k $12.7m | Reduced -23.4k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.30% of their portfolio | 83.4k $12.5m | Added +20.2k |
| HSBC HOLDINGS PLC 0.01% of their portfolio | 81.8k $12.3m | Added +1.6k |
| Artisan Partners Limited Partnership 0.02% of their portfolio | 81.8k $12.3m | New |
| California Public Employees Retirement System 0.01% of their portfolio | 81.4k $12.3m | Reduced -3.5k |
| GCM Grosvenor Holdings, LLC 1.87% of their portfolio | 80.2k $12.1m | New |
| KBC Group NV 0.04% of their portfolio | 76.3k $11.5m | Reduced -9.1k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 76.0k $11.4m | Reduced -95.3k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 74.5k $11.2m | Reduced -297.7k |
| FRONTIER CAPITAL MANAGEMENT CO LLC 0.12% of their portfolio | 71.1k $10.7m | Reduced -2.1k |
| NICHOLAS COMPANY, INC. 0.18% of their portfolio | 69.4k $10.5m | Unchanged |
| TUDOR INVESTMENT CORP ET AL 0.09% of their portfolio | 69.1k $10.4m | Added +12.8k |
| INVESTMENT HOUSE LLC 0.56% of their portfolio | 65.6k $9.9m | Added +315 |
| Mitsubishi UFJ Trust & Banking Corp 0.03% of their portfolio | 64.3k $9.7m | Reduced -28.1k |
| IRIDIAN ASSET MANAGEMENT LLC/CT 2.85% of their portfolio | 60.4k $9.1m | Added +9.5k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 57.6k $8.7m | Reduced -1.6k |
| CI INVESTMENTS INC. 0.04% of their portfolio | 56.3k $8.5m | Reduced -29.9k |
| LAWSON KROEKER INVESTMENT MANAGEMENT INC/NE 1.56% of their portfolio | 56.0k $8.4m | Added +954 |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 55.0k $8.3m | Reduced -9.0k |
| Mitsubishi UFJ Asset Management Co., Ltd. 0.01% of their portfolio | 54.5k $8.2m | Reduced -26.3k |
| Balyasny Asset Management L.P. 0.02% of their portfolio | 52.8k $7.9m | Added +47.1k |
| Mawer Investment Management Ltd. 0.04% of their portfolio | 51.9k $7.8m | Added +5.3k |