Vault-13

CHARLES RIV LABS INTL INC CRL

COM · Common Stock · CUSIP 159864107 · ISIN US1598641074

Major US biomedical company

629 institutional holders +45 vs Q3 2022
49,747,87849.7m shares reported held*
97.6% of all shares outstanding*
$10.8bnreported value*
87 new 225 added 218 reduced 53 sold out net sold ≈ $102.7m (-459.7k shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($23.8m this quarter). Holder counts are more reliable. Shares outstanding: 51.0m as of 2023-01-25, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $217.93. Options: 10 managers hold calls ($19.4m notional), 12 hold puts ($43.0m).

Trends to Q4 2022

Institutional holders

Managers reporting a position, each quarter

0250500750Q3 22: 584Q4 22: 629629Q3 22Q4 22
Numbers
QuarterHolders
Q3 2022584
Q4 2022629

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$20m$40m$60mQ3 22 calls: $33.9mQ3 22 puts: $13.3mQ3 22P/C 0.39Q4 22 calls: $19.4mQ4 22 puts: $43.0mQ4 22P/C 2.21
Numbers
QuarterCallsPutsP/C
Q3 2022$33.9m$13.3m0.39
Q4 2022$19.4m$43.0m2.21

Biggest buyers

MILLENNIUM MANAGEMENT LLC New +437,787+437.8k
MARSHALL WACE, LLP Added +319,095+319.1k
TPG GP A, LLC New +302,263+302.3k
AMERIPRISE FINANCIAL INC Added +299,953+300.0k
PRICE T ROWE ASSOCIATES INC /MD/ Added +266,004+266.0k
MORGAN STANLEY Added +193,250+193.2k
Allspring Global Investments Holdings, LLC Added +171,479+171.5k
VOYA INVESTMENT MANAGEMENT LLC Added +156,987+157.0k
LORD, ABBETT & CO. LLC Added +144,008+144.0k
VICTORY CAPITAL MANAGEMENT INC Added +125,987+126.0k

Biggest sellers

Camber Capital Management LP Sold out -500,000-500.0k
Southpoint Capital Advisors LP Sold out -500,000-500.0k
BlackRock Inc. Reduced -350,971-351.0k
Alyeska Investment Group, L.P. Sold out -333,429-333.4k
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ Sold out -270,130-270.1k
VOLORIDGE INVESTMENT MANAGEMENT, LLC Sold out -217,836-217.8k
Point72 Asset Management, L.P. Sold out -211,900-211.9k
FMR LLC Reduced -182,578-182.6k
TWO SIGMA ADVISERS, LP Reduced -151,100-151.1k
Baird Financial Group, Inc. Sold out -150,586-150.6k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $12.0m55.1k shares
CITADEL ADVISORS LLC Reduced $2.7m12.4k shares
TUDOR INVESTMENT CORP ET AL Added $1.4m6.3k shares
Walleye Trading LLC Added $1.1m4.9k shares
WOLVERINE TRADING, LLC Added $1.0m4.7k shares
TWO SIGMA SECURITIES, LLC Reduced $588.3k2.7k shares
PEAK6 Investments LLC Reduced $283.3k1.3k shares
SIMPLEX TRADING, LLC Reduced $239.0k1.1k shares
GROUP ONE TRADING LLC Reduced $152.5k700 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $18.7m85.7k shares
GROUP ONE TRADING LLC New $10.1m46.5k shares
CITADEL ADVISORS LLC Added $5.7m26.3k shares
SIMPLEX TRADING, LLC Added $3.0m14.0k shares
TUDOR INVESTMENT CORP ET AL Added $1.2m5.4k shares
JANE STREET GROUP, LLC New $1.1m5.2k shares
MILLENNIUM MANAGEMENT LLC Reduced $1.1m5.0k shares
WOLVERINE TRADING, LLC Added $959.0k4.4k shares
Walleye Trading LLC Added $740.9k3.4k shares
TWO SIGMA SECURITIES, LLC Reduced $217.9k1.0k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
FMR LLC 13G · institution +1.4 pts · filed 2026-09-08 10.2% +1.4 pts 4.9m≈ $1.1bn 2026-09-08
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-29 7.4% new 3.6m≈ $824.2m 2026-04-29
BlackRock, Inc. 13G · institution filed 2025-04-17 6.9% 3.5m≈ $799.3m 2025-04-17
Invesco Ltd. 13G · institution +1.3 pts · filed 2026-08-13 6.2% +1.3 pts 3.0m≈ $676.9m 2026-08-13

Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26; now reported by VANGUARD CAPITAL MANAGEMENT LLC), WELLINGTON MANAGEMENT GROUP LLP (3.6%, 2026-02-10), NOMURA HOLDINGS INC (1.6%, 2025-11-14)

Insider purchases and sales in Q4 2022

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
404Q1 21: 0 buyingQ1 21: 0 sellingQ2 21: 0 buyingQ2 21: 0 sellingQ2 21Q3 21: 0 buyingQ3 21: 0 sellingQ4 21: 0 buyingQ4 21: 0 sellingQ4 21Q1 22: 0 buyingQ1 22: 4 sellingQ2 22: 0 buyingQ2 22: 1 sellingQ2 22Q3 22: 0 buyingQ3 22: 1 sellingQ4 22: 1 buyingQ4 22: 4 sellingQ4 22
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q1 20210—0——
Q2 20210—0——
Q3 20210—0——
Q4 20210—0——
Q1 20220—4$22.4m—
Q2 20220—1$41.1k—
Q3 20220—1$45.2k—
Q4 20221$328.4k4$3.0m—
DateInsiderTradeSharesPrice ValueTheir holding
2022-12-02 Barbo William D Corporate Executive VP & CCO Sold 3,205 $219.91 $704.8k3.2k shares -46%
2022-12-02 WALLMAN RICHARD F Director Bought 1,500 $218.90 $328.4k1.5k shares +8%
2022-12-01 LaPlume Joseph W EVP, Corp Strategy & Develop Sold 6,409 $224.25 $1.4m6.4k shares -24%
2022-11-16 Knell Michael Gunnar CSVP&Chief Accounting Officer Sold 855 $248.59 $212.5k855 shares -12%
2022-11-15 Parisotto Shannon M CEVP, Disc & Safety Assessment Sold 2,279 $249.90 $569.5k2.3k shares -48%
2022-11-04 LaPlume Joseph W EVP, Corp Strategy & Develop Sold 534 $216.36 $115.5k534 shares -3%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q4 2022

#ManagerLocationShares Value% of their portfolioChangeShares change
1 VANGUARD GROUP INC 0.04% of their portfolio Valley Forge, PA 5,956,9606.0m $1.3bn $1.3bn 0.04% Reduced -20.2k -20,159
2 BlackRock Inc. 0.03% of their portfolio New York, NY 4,958,2275.0m $1.1bn $1.1bn 0.03% Reduced -351.0k -350,971
3 STATE STREET CORP 0.03% of their portfolio BOSTON, MA 2,066,2892.1m $450.2m $450.2m 0.03% Added +35.1k +35,148
4 PRICE T ROWE ASSOCIATES INC /MD/ 0.06% of their portfolio BALTIMORE, MD 1,852,5031.9m $403.7m $403.7m 0.06% Added +266.0k +266,004
5 KAYNE ANDERSON RUDNICK INVESTMENT MANAGEMENT LLC 1.10% of their portfolio LOS ANGELES, CA 1,616,8001.6m $352.3m $352.3m 1.10% Reduced -15.5k -15,461
6 Clearbridge Investments, LLC 0.30% of their portfolio NEW YORK, NY 1,370,8581.4m $298.7m $298.7m 0.30% Reduced -78.7k -78,671
7 Allspring Global Investments Holdings, LLC 0.43% of their portfolio CHARLOTTE, NC 1,147,8261.1m $250.1m $250.1m 0.43% Added +171.5k +171,479
8 GEODE CAPITAL MANAGEMENT, LLC 0.03% of their portfolio BOSTON, MA 1,037,3971.0m $225.6m $225.6m 0.03% Added +42.5k +42,486
9 Invesco Ltd. 0.06% of their portfolio ATLANTA, GA 899,490899.5k $196.0m $196.0m 0.06% Reduced -126.4k -126,369
10 MARSHALL WACE, LLP 0.49% of their portfolio LONDON, X0 874,773874.8k $190.6m $190.6m 0.49% Added +319.1k +319,095
11 Jackson Square Partners, LLC 5.00% of their portfolio LARKSPUR, CA 861,123861.1k $187.6m $187.6m 5.00% Reduced -9.7k -9,665
12 MACKENZIE FINANCIAL CORP 0.29% of their portfolio TORONTO ONTARIO, A6 800,576800.6k $174.4m $174.4m 0.29% Added +89.8k +89,751
13 FIL Ltd 0.20% of their portfolio HAMILTON, D0 758,305758.3k $165.2m $165.2m 0.20% Added +29.4k +29,368
14 WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC 0.59% of their portfolio CHICAGO, IL 710,020710.0k $154.7m $154.7m 0.59% Reduced -17.5k -17,536
15 FRANKLIN RESOURCES INC 0.08% of their portfolio San Mateo, CA 695,212695.2k $151.5m $151.5m 0.08% Added +50.0k +50,044
16 BANK OF AMERICA CORP /DE/ 0.02% of their portfolio CHARLOTTE, NC 668,685668.7k $145.7m $145.7m 0.02% Added +41.7k +41,744
17 ARIEL INVESTMENTS, LLC 1.41% of their portfolio CHICAGO, IL 637,762637.8k $139.0m $139.0m 1.41% Reduced -12.7k -12,736
18 FMR LLC 0.01% of their portfolio BOSTON, MA 557,206557.2k $121.4m $121.4m 0.01% Reduced -182.6k -182,578
19 VIKING GLOBAL INVESTORS LP 0.56% of their portfolio STAMFORD, CT 515,168515.2k $112.3m $112.3m 0.56% Reduced -143.3k -143,310
20 NORTHERN TRUST CORP 0.02% of their portfolio CHICAGO, IL 496,299496.3k $108.1m $108.1m 0.02% Added +1.7k +1,724
21 EARNEST PARTNERS LLC 0.64% of their portfolio ATLANTA, GA 478,586478.6k $104.3m $104.3m 0.64% Added +15.3k +15,286
22 MORGAN STANLEY 0.01% of their portfolio NEW YORK, NY 474,431474.4k $103.4m $103.4m 0.01% Added +193.2k +193,250
23 WELLS FARGO & COMPANY/MN 0.03% of their portfolio SAN FRANCISCO, CA 467,549467.5k $101.9m $101.9m 0.03% Reduced -17.2k -17,165
24 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.03% of their portfolio SAN FRANCISCO, CA 463,605463.6k $101.0m $101.0m 0.03% Added +22.4k +22,438
25 CONGRESS ASSET MANAGEMENT CO 0.99% of their portfolio BOSTON, MA 452,440452.4k $98.6m $98.6m 0.99% Reduced -29.5k -29,537
26 NORGES BANK 0.02% of their portfolio OSLO, Q8 448,256448.3k $97.7m $97.7m 0.02% Reduced -20.5k -20,539
27 MONTRUSCO BOLTON INVESTMENTS INC. 2.18% of their portfolio MONTREAL, A8 443,846443.8k $94.0m $94.0m 2.18% Added +110.1k +110,107
28 MILLENNIUM MANAGEMENT LLC 0.11% of their portfolio NEW YORK, NY 437,787437.8k $95.4m $95.4m 0.11% New
29 SEI INVESTMENTS CO 0.21% of their portfolio OAKS, PA 434,281434.3k $94.6m $94.6m 0.21% Added +1.5k +1,482
30 KING LUTHER CAPITAL MANAGEMENT CORP 0.51% of their portfolio FORT WORTH, TX 430,596430.6k $93.8m $93.8m 0.51% Reduced -48.5k -48,499
31 Bank of New York Mellon Corp 0.02% of their portfolio NEW YORK, NY 423,554423.6k $92.3m $92.3m 0.02% Reduced -59.2k -59,172
32 VOYA INVESTMENT MANAGEMENT LLC 0.09% of their portfolio ATLANTA, GA 346,781346.8k $75.6m $75.6m 0.09% Added +157.0k +156,987
33 VICTORY CAPITAL MANAGEMENT INC 0.09% of their portfolio San Antonio, TX 340,781340.8k $74.3m $74.3m 0.09% Added +126.0k +125,987
34 DIMENSIONAL FUND ADVISORS LP 0.02% of their portfolio AUSTIN, TX 320,625320.6k $69.9m $69.9m 0.02% Added +31.4k +31,420
35 AMERIPRISE FINANCIAL INC 0.02% of their portfolio MINNEAPOLIS, MN 318,497318.5k $69.4m $69.4m 0.02% Added +300.0k +299,953
36 TPG GP A, LLC 1.29% of their portfolio FORT WORTH, TX 302,263302.3k $65.9m $65.9m 1.29% New
37 Legal & General Group Plc 0.03% of their portfolio London, X0 301,127301.1k $65.6m $65.6m 0.03% Reduced -12.9k -12,862
38 RIVERBRIDGE PARTNERS LLC 0.98% of their portfolio MINNEAPOLIS, MN 300,808300.8k $65.5m $65.5m 0.98% Reduced -18.4k -18,412
39 FIRST TRUST ADVISORS LP 0.08% of their portfolio Wheaton, IL 296,223296.2k $64.6m $64.6m 0.08% Added +29.1k +29,098
40 Bellevue Group AG 0.84% of their portfolio ZURICH, V8 289,977290.0k $63.2m $63.2m 0.84% Added +27.0k +26,984
41 PRIMECAP MANAGEMENT CO/CA/ 0.06% of their portfolio PASADENA, CA 284,740284.7k $62.0m $62.0m 0.06% Reduced -10.1k -10,080
42 LORD, ABBETT & CO. LLC 0.10% of their portfolio JERSEY CITY, NJ 260,460260.5k $56.8m $56.8m 0.10% Added +144.0k +144,008
43 HORIZON KINETICS ASSET MANAGEMENT LLC 0.94% of their portfolio NEW YORK, NY 260,093260.1k $56.7m $56.7m 0.94% Reduced -24.3k -24,296
44 NEUBERGER BERMAN GROUP LLC 0.05% of their portfolio NEW YORK, NY 256,808256.8k $56.0m $56.0m 0.05% Reduced -706 -706
45 Fisher Asset Management, LLC 0.04% of their portfolio PLANO, TX 251,140251.1k $54.7m $54.7m 0.04% Added +10.4k +10,381
46 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.03% of their portfolio Toronto, A6 236,619236.6k $51.7m $51.7m 0.03% Added +15.8k +15,842
47 RAYMOND JAMES & ASSOCIATES 0.04% of their portfolio ST PETERSBURG, FL 223,717223.7k $48.7m $48.7m 0.04% Reduced -7.8k -7,786
48 Premier Fund Managers Ltd 1.92% of their portfolio GUILDFORD, X0 220,000220.0k $49.2m $49.2m 1.92% Added +109.0k +109,000
49 WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio Boston, MA 210,650210.7k $45.9m $45.9m 0.01% Added +24 +24
50 Nuveen Asset Management, LLC 0.02% of their portfolio CHICAGO, IL 208,408208.4k $45.4m $45.4m 0.02% Reduced -30.6k -30,564
51 EAGLE ASSET MANAGEMENT INC 0.28% of their portfolio ST PETERSBURG, FL 208,086208.1k $45.4m $45.4m 0.28% Reduced -262 -262
52 Swiss National Bank 0.03% of their portfolio ZURICH, V8 206,700206.7k $45.0m $45.0m 0.03% Reduced -13.5k -13,500
53 Iron Triangle Partners LP 7.81% of their portfolio Cos Cob, CT 200,000200.0k $43.6m $43.6m 7.81% Reduced -2.0k -2,000
54 STRS OHIO 0.20% of their portfolio COLUMBUS, OH 199,000199.0k $43.4m $43.4m 0.20% Added +25.0k +25,000
55 BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.15% of their portfolio Paris, I0 196,036196.0k $42.7m $42.7m 0.15% Added +22.9k +22,918
56 DEUTSCHE BANK AG\ 0.02% of their portfolio FRANKFURT AM MAIN, 2M 188,646188.6k $41.1m $41.1m 0.02% Added +3.2k +3,223
57 Van Berkom & Associates Inc. 1.68% of their portfolio MONTREAL, A8 180,050180.1k $39.2m $39.2m 1.68% Added +9 +9
58 ROYAL BANK OF CANADA 0.01% of their portfolio TORONTO, A6 170,960171.0k $37.3m $37.3m 0.01% Reduced -10.9k -10,936
59 ARGENT CAPITAL MANAGEMENT LLC 1.33% of their portfolio ST LOUIS, MO 170,231170.2k $37.1m $37.1m 1.33% Added +780 +780
60 AMERICAN CAPITAL MANAGEMENT INC 1.44% of their portfolio NEW YORK, NY 169,000169.0k $36.8m $36.8m 1.44% Reduced -1.0k -1,000
61 BROWN ADVISORY INC 0.07% of their portfolio BALTIMORE, MD 165,508165.5k $36.1m $36.1m 0.07% Reduced -19.3k -19,315
62 PERSONAL CAPITAL ADVISORS CORP 0.17% of their portfolio Redwood City, CA 160,483160.5k $35.0m $35.0m 0.17% Reduced -16.7k -16,743
63 ENVESTNET ASSET MANAGEMENT INC 0.02% of their portfolio Berwyn, PA 160,363160.4k $34.9m $34.9m 0.02% Reduced -3.5k -3,456
64 Mitsubishi UFJ Trust & Banking Corp 0.09% of their portfolio TOKYO, M0 158,476158.5k $34.5m $34.5m 0.09% Reduced -690 -690
65 Aristotle Capital Boston, LLC 1.06% of their portfolio BOSTON, MA 153,805153.8k $33.5m $33.5m 1.06% Reduced -4.4k -4,353
66 SNYDER CAPITAL MANAGEMENT L P 0.74% of their portfolio San Francisco, CA 150,201150.2k $32.7m $32.7m 0.74% Reduced -2.3k -2,292
67 FEDERATED HERMES, INC. 0.09% of their portfolio PITTSBURGH, PA 150,028150.0k $32.7m $32.7m 0.09% Reduced -36.9k -36,889
68 Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio CHIYODA-KU, TOKYO, M0 142,185142.2k $31.0m $31.0m 0.02% Reduced -615 -615
69 Boston Trust Walden Corp 0.27% of their portfolio BOSTON, MA 140,589140.6k $30.6m $30.6m 0.27% Added +40.3k +40,316
70 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 136,600136.6k $29.8m $29.8m 0.00% Reduced -3.0k -2,964
71 M.D. Sass, LLC 5.08% of their portfolio New York, NY 130,053130.1k $28.3m $28.3m 5.08% Reduced -8.4k -8,361
72 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio NEW YORK, NY 128,664128.7k $28.0m $28.0m 0.01% Reduced -508 -508
73 SANDLER CAPITAL MANAGEMENT 4.05% of their portfolio NEW YORK, NY 121,400121.4k $26.5m $26.5m 4.05% New
74 J.P. Morgan Private Wealth Advisors LLC 0.06% of their portfolio SAN FRANCISCO, CA 121,139121.1k $26.4m $26.4m 0.06% Reduced -36.1k -36,136
75 Skandinaviska Enskilda Banken AB (publ) 0.19% of their portfolio STOCKHOLM, V7 114,757114.8k $25.0m $25.0m 0.19% Added +570 +570
76 Amundi 0.02% of their portfolio Paris, I0 112,427112.4k $27.8m $27.8m 0.02% Reduced -25.8k -25,753
77 California Public Employees Retirement System 0.02% of their portfolio Sacramento, CA 111,975112.0k $24.4m $24.4m 0.02% Reduced -1.6k -1,578
78 GOLDMAN SACHS GROUP INC 0.01% of their portfolio NEW YORK, NY 111,735111.7k $24.3m $24.3m 0.01% Reduced -6.6k -6,639
79 MOUNTAIN PACIFIC INVESTMENT ADVISERS LLC 1.69% of their portfolio BOISE, ID 107,071107.1k $23.3m $23.3m 1.69% Added +17.2k +17,170
80 KETTLE HILL CAPITAL MANAGEMENT, LLC 4.44% of their portfolio New York, NY 103,637103.6k $22.6m $22.6m 4.44% New
81 CIBC Private Wealth Group LLC 0.07% of their portfolio ATLANTA, GA 103,413103.4k $22.0m $22.0m 0.07% Reduced -59 -59
82 NATIONAL BANK OF CANADA /FI/ 0.06% of their portfolio MONTREAL, A8 102,363102.4k $22.3m $22.3m 0.06% Added +51.3k +51,321
83 Soleus Capital Management, L.P. 3.18% of their portfolio GREENWICH, CT 101,850101.8k $22.2m $22.2m 3.18% Reduced -27.2k -27,250
84 NORRIS PERNE & FRENCH LLP/MI 2.16% of their portfolio GRAND RAPIDS, MI 100,619100.6k $21.9m $21.9m 2.16% Reduced -2.3k -2,284
85 TWO SIGMA ADVISERS, LP 0.06% of their portfolio NEW YORK, NY 95,20095.2k $20.7m $20.7m 0.06% Reduced -151.1k -151,100
86 STIFEL FINANCIAL CORP 0.03% of their portfolio ST. LOUIS, MO 94,82894.8k $20.7m $20.7m 0.03% Reduced -5.1k -5,137
87 LAKEWOOD CAPITAL MANAGEMENT, LP 1.70% of their portfolio New York, NY 87,74087.7k $19.1m $19.1m 1.70% Reduced -18.0k -18,000
88 Swedbank AB 0.04% of their portfolio STOCKHOLM, V7 86,90086.9k $18.9m $18.9m 0.04% New
89 RHUMBLINE ADVISERS 0.03% of their portfolio BOSTON, MA 86,03686.0k $18.7m $18.7m 0.03% Added +2.7k +2,715
90 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.03% of their portfolio WEST SACRAMENTO, CA 85,43185.4k $18.6m $18.6m 0.03% Added +1.1k +1,062
91 UBS Group AG 0.01% of their portfolio ZURICH, V8 84,45084.5k $18.4m $18.4m 0.01% Added +30.7k +30,663
92 INVESTMENT HOUSE LLC 1.64% of their portfolio REDONDO BEACH, CA 80,55480.6k $17.6m $17.6m 1.64% Reduced -1.6k -1,550
93 IRIDIAN ASSET MANAGEMENT LLC/CT 1.65% of their portfolio WESTPORT, CT 78,67678.7k $17.1m $17.1m 1.65% Reduced -9.3k -9,288
94 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.28% of their portfolio BALA CYNWYD, PA 75,59675.6k $16.5m $16.5m 0.28% Added +8.8k +8,783
95 PFM Health Sciences, LP 0.67% of their portfolio SAN FRANCISCO, CA 72,82072.8k $15.9m $15.9m 0.67% New
96 Tekla Capital Management LLC 0.60% of their portfolio Boston, MA 72,67572.7k $15.8m $15.8m 0.60% Unchanged
97 CI INVESTMENTS INC. 0.08% of their portfolio TORONTO, Z4 71,44671.4k $15.6m $15.6m 0.08% Added +29.6k +29,554
98 BAILLIE GIFFORD & CO 0.02% of their portfolio EDINBURGH, X0 71,37271.4k $15.6m $15.6m 0.02% Reduced -527 -527
99 PINEBRIDGE INVESTMENTS, L.P. 0.18% of their portfolio NEW YORK, NY 70,02070.0k $15.3m $15.3m 0.18% Added +14.0k +13,958
100 Laurus Global Equity Management Inc. 7.68% of their portfolio TORONTO, A6 70,00370.0k $20.7m $20.7m 7.68% Reduced -627 -627