CENTURY THERAPEUTICS INC IPSC
COM · Common Stock · CUSIP 15673T100
Company in Philadelphia, United States
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersPhiladelphia, PA
- Founded2018
- Websitecenturytx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 181.1m as of 2026-08-03, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.45. Options: 3 managers hold calls ($542.9k notional), 4 hold puts ($329.5k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 54 |
| Q4 2022 | 66 |
| Q1 2023 | 65 |
| Q2 2023 | 65 |
| Q3 2023 | 56 |
| Q4 2023 | 64 |
| Q1 2024 | 68 |
| Q2 2024 | 62 |
| Q3 2024 | 68 |
| Q4 2024 | 73 |
| Q1 2025 | 71 |
| Q2 2025 | 66 |
| Q3 2025 | 57 |
| Q4 2025 | 47 |
| Q1 2026 | 72 |
| Q2 2026 | 99 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 30 | 21 |
| Q4 2024 | 43 | 20 |
| Q1 2025 | 22 | 36 |
| Q2 2025 | 35 | 47 |
| Q3 2025 | 15 | 41 |
| Q4 2025 | 15 | 31 |
| Q1 2026 | 45 | 17 |
| Q2 2026 | 65 | 22 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $0 | $0 | — |
| Q4 2025 | $0 | $1.9k | — |
| Q1 2026 | $103.1k | $4.3k | 0.04 |
| Q2 2026 | $542.9k | $329.5k | 0.61 |
Biggest buyers
| BlackRock, Inc. | Added | +6.6m |
| STEMPOINT CAPITAL LP | New | +2.1m |
| Trails Edge Capital Partners, LP | Added | +1.7m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +1.7m |
| STATE STREET CORP | Added | +1.5m |
| NORTHERN TRUST CORP | Added | +1.4m |
| Woodline Partners LP | Added | +1.2m |
| VANGUARD PORTFOLIO MANAGEMENT LLC | New | +1.0m |
| Balyasny Asset Management L.P. | Added | +505.2k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +350.9k |
Biggest sellers
| Syncona Portfolio Ltd | Sold out | -1.2m |
| Point72 Asset Management, L.P. | Reduced | -984.2k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -472.1k |
| ACADIAN ASSET MANAGEMENT LLC | Sold out | -278.1k |
| MARSHALL WACE, LLP | Reduced | -135.6k |
| SUPERSTRING CAPITAL MANAGEMENT LP | Sold out | -119.3k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -110.9k |
| Brevan Howard Capital Management LP | Sold out | -96.6k |
| BARCLAYS PLC | Reduced | -95.5k |
| GOLDMAN SACHS GROUP INC | Reduced | -60.0k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $276.9k113.0k shares |
| JANE STREET GROUP, LLC | Added | $186.9k76.3k shares |
| SIMPLEX TRADING, LLC | Added | $79.1k32.3k shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $275.1k112.3k shares |
| JANE STREET GROUP, LLC | New | $53.9k22.0k shares |
| GROUP ONE TRADING LLC | New | $245100 shares |
| SIMPLEX TRADING, LLC | Reduced | $245100 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor new · filed 2026-01-16 | 9.9% |
| TCG Crossover GP II, LLC 13G · passive investor new · filed 2026-01-15 | 9.9% |
| Deep Track Capital, LP 13G · passive investor new · filed 2026-01-15 | 7.3% |
| RTW INVESTMENTS, LP 13G · institution new · filed 2026-05-15 | 7.1% |
| Venrock Healthcare Capital Partners III, L.P. 13G · passive investor +2.4 pts · filed 2026-01-16 | 7.1% |
| Commodore Capital LP 13G · passive investor new · filed 2026-01-16 | 7.1% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (3.3%, 2026-05-15), Bain Capital Life Sciences Opportunities III, LP (4.1%, 2025-11-14)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 2 | $1.6k | — |
| Q1 2025 | 0 | — | 4 | $33.3k | — |
| Q2 2025 | 0 | — | 4 | $21.0k | — |
| Q3 2025 | 0 | — | 3 | $802 | — |
| Q4 2025 | 2 | $97.0k | 4 | $17.9k | — |
| Q1 2026 | 0 | — | 2 | $46.1k | — |
| Q2 2026 | 0 | — | 2 | $11.7k | — |
| Q3 2026 | 0 | — | 2 | $10.4k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-14 | Russotti Gregory Officer | Sold | $5.0k2.6k shares |
| 2026-09-14 | Carr Douglas SVP Finance & Operations | Sold | $3.2k1.7k shares |
| 2026-09-08 | Russotti Gregory Officer | Sold | $1.1k534 shares |
| 2026-09-08 | Carr Douglas SVP Finance & Operations | Sold | $521254 shares |
| 2026-08-03 | Carr Douglas SVP Finance & Operations | Sold | $544275 shares |
| 2026-06-12 | Russotti Gregory Officer | Sold | $5.8k2.6k shares |
| 2026-06-12 | Carr Douglas SVP Finance & Operations | Sold | $3.7k1.7k shares |
| 2026-06-08 | Russotti Gregory Officer | Sold | $1.1k524 shares |
| 2026-06-08 | Carr Douglas SVP Finance & Operations | Sold | $525249 shares |
| 2026-05-04 | Carr Douglas SVP Finance & Operations | Sold | $618264 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. 0.38% of their portfolio | 17.8m $43.5m | Unchanged |
| TCG Crossover Management, LLC 1.04% of their portfolio | 17.8m $43.4m | Unchanged |
| Versant Venture Management, LLC 18.33% of their portfolio | 12.2m $29.8m | Unchanged |
| Deep Track Capital, LP 0.34% of their portfolio | 9.5m $23.2m | Reduced -25.1k |
| RTW INVESTMENTS, LP 0.18% of their portfolio | 8.7m $21.3m | Unchanged |
| Venrock Adviser, LLC 0.65% of their portfolio | 8.7m $21.3m | Unchanged |
| Commodore Capital LP 1.27% of their portfolio | 8.7m $21.3m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 8.1m $19.8m | Added +6.6m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 5.7m $14.0m | Added +17.5k |
| Balyasny Asset Management L.P. 0.02% of their portfolio | 5.5m $13.5m | Added +505.2k |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 5.0m $12.2m | Reduced -984.2k |
| Seven Fleet Capital Management LP 1.76% of their portfolio | 4.3m $10.7m | Unchanged |
| Woodline Partners LP 0.03% of their portfolio | 4.3m $10.4m | Added +1.2m |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 4.2m $10.3m | Reduced -472.1k |
| Trails Edge Capital Partners, LP 1.61% of their portfolio | 4.1m $10.1m | Added +1.7m |
| Spruce Street Capital LP 1.95% of their portfolio | 4.1m $9.9m | Unchanged |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 3.8m $9.3m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 3.0m $7.3m | Added +1.7m |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 2.7m $6.6m | Added +327.6k |
| DAFNA Capital Management LLC 1.12% of their portfolio | 2.4m $5.9m | Reduced -33.9k |
| STEMPOINT CAPITAL LP 0.91% of their portfolio | 2.1m $5.3m | New |
| STATE STREET CORP 0.00% of their portfolio | 1.8m $4.5m | Added +1.5m |
| NORTHERN TRUST CORP 0.00% of their portfolio | 1.6m $3.9m | Added +1.4m |
| DV Trading LLC 0.28% of their portfolio | 1.4m $3.4m | Unchanged |
| Rock Springs Capital Management LP 0.16% of their portfolio | 1.3m $3.2m | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 1.3m $3.1m | Added +350.9k |
| Casdin Capital, LLC 0.15% of their portfolio | 1.2m $3.0m | Unchanged |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.0m $2.5m | New |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 737.5k $1.8m | Added +44.6k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 538.0k $1.3m | Reduced -135.6k |
| Invesco Ltd. 0.00% of their portfolio | 381.4k $934.5k | Added +319.3k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 378.9k $928.2k | Added +299.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 299.0k $732.6k | Added +286.1k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 271.5k $664.7k | Added +216.3k |
| UBS Group AG 0.00% of their portfolio | 232.4k $569.4k | Added +218.2k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 174.1k $426.5k | Added +115.3k |
| Nuveen, LLC 0.00% of their portfolio | 163.6k $400.8k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 158.9k $389.3k | Added +13.8k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 150.4k $368.6k | Reduced -60.0k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 148.9k $364.8k | Added +148.9k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 128.4k $314.6k | New |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 126.5k $309.9k | New |
| GSA CAPITAL PARTNERS LLP 0.02% of their portfolio | 120.6k $295.0k | Added +43.8k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 120.2k $294.6k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 115.8k $283.7k | Reduced -110.9k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 101.2k $248.0k | New |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 91.3k $223.7k | Unchanged |
| Squarepoint Ops LLC 0.00% of their portfolio | 90.1k $220.9k | Reduced -29.4k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 81.9k $200.7k | New |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 77.8k $175.1k | Added +33 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 76.3k $186.9k | New |
| AXQ CAPITAL, LP 0.02% of their portfolio | 59.1k $144.7k | New |
| Spark Investment Management LLC 0.28% of their portfolio | 59.0k $144.6k | New |
| CITIGROUP INC 0.00% of their portfolio | 57.0k $139.7k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 56.5k $138.4k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 51.2k $123.4k | Added +51.1k |
| Verdad Advisers, LP 0.11% of their portfolio | 46.2k $113.2k | New |
| Quadrature Capital Ltd 0.00% of their portfolio | 45.9k $112.4k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 44.6k $109.3k | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 44.0k $107.7k | New |
| MORGAN STANLEY 0.00% of their portfolio | 38.5k $94.2k | Added +12.2k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 36.3k $89.1k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 34.6k $84.8k | New |
| State of Wyoming 0.01% of their portfolio | 33.4k $81.9k | New |
| Virtu Financial LLC 0.00% of their portfolio | 31.1k $76.0k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 29.8k $67.3k | New |
| HarbourVest Partners LLC 0.04% of their portfolio | 29.0k $71.1k | Unchanged |
| Parametrica Management Ltd 0.05% of their portfolio | 27.8k $68.2k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 25.6k $62.6k | Added +24.1k |
| Magnus Financial Group LLC 0.00% of their portfolio | 25.3k $62.0k | New |
| BARCLAYS PLC 0.00% of their portfolio | 24.7k $60.5k | Reduced -95.5k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 24.4k $59.8k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 24.1k $59.0k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 22.7k $55.6k | New |
| Schonfeld Strategic Advisors LLC 0.00% of their portfolio | 21.5k $52.8k | New |
| Quadrant Private Wealth Management, LLC 0.01% of their portfolio | 20.0k $49.1k | Unchanged |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 18.6k $45.6k | Reduced -6.7k |
| ProShare Advisors LLC 0.00% of their portfolio | 16.1k $39.5k | New |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 14.1k $34.5k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 12.5k $30.6k | Reduced -20.5k |
| XPONANCE LLC 0.00% of their portfolio | 11.8k $28.8k | New |
| HRT FINANCIAL LP 0.00% of their portfolio | 11.3k $27.0k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 11.2k $27.4k | New |
| FNY Investment Advisers, LLC 0.01% of their portfolio | 10.0k $24.0k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 9.9k $24.1k | New |
| FMR LLC 0.00% of their portfolio | 9.0k $22.0k | Added +215 |
| Advisors Asset Management, Inc. 0.00% of their portfolio | 8.3k $20.4k | Added +2 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 6.4k $15.0k | Added +2.0k |
| Sterling Capital Management LLC 0.00% of their portfolio | 2.5k $6.1k | New |
| Truvestments Capital LLC 0.00% of their portfolio | 2.3k $5.7k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 1.7k $4.2k | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 1.2k $3.0k | Reduced -42 |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 883 $2.2k | Unchanged |
| MARK SHEPTOFF FINANCIAL PLANNING, LLC 0.00% of their portfolio | 500 $1.2k | Unchanged |
| Optiver Holding B.V. 0.00% of their portfolio | 368 $902 | Added +336 |
| Fortitude Family Office, LLC 0.00% of their portfolio | 294 $720 | Unchanged |
| Arax Advisory Partners 0.00% of their portfolio | 99 $243 | Unchanged |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 35 $86 | New |
| Smartleaf Asset Management LLC 0.00% of their portfolio | 1 $2 | Unchanged |