Vault-13

CENTURY THERAPEUTICS INC IPSC

COM · Common Stock · CUSIP 15673T100

Company in Philadelphia, United States

62 institutional holders -6 vs Q1 2024
40,138,08540.1m shares reported held*
47.4% of all shares outstanding*
$102.4mreported value*
5 new 32 added 14 reduced 13 sold out net bought ≈ $42.2m (+16.5m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 84.7m as of 2024-08-01, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.55. Options: 2 managers hold calls ($17.9k notional), 2 hold puts ($765).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

0255075Q3 22: 54Q4 22: 66Q1 23: 65Q2 23: 65Q3 23: 56Q4 23: 64Q1 24: 68Q2 24: 6262Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 202254
Q4 202266
Q1 202365
Q2 202365
Q3 202356
Q4 202364
Q1 202468
Q2 202462

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
50050Q4 22: 39 bought or addedQ4 22: 18 cut or sold outQ4 22Q1 23: 41 bought or addedQ1 23: 32 cut or sold outQ2 23: 25 bought or addedQ2 23: 29 cut or sold outQ2 23Q3 23: 21 bought or addedQ3 23: 33 cut or sold outQ4 23: 36 bought or addedQ4 23: 25 cut or sold outQ4 23Q1 24: 29 bought or addedQ1 24: 31 cut or sold outQ2 24: 37 bought or addedQ2 24: 27 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 20223918
Q1 20234132
Q2 20232529
Q3 20232133
Q4 20233625
Q1 20242931
Q2 20243727

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$20k$40k$60kQ3 23 calls: $7.2kQ3 23 puts: $3.4kQ3 23P/C 0.47Q4 23 calls: $16.0kQ4 23 puts: $1.3kQ4 23P/C 0.08Q1 24 calls: $44.3kQ1 24 puts: $1.3kQ1 24P/C 0.03Q2 24 calls: $17.9kQ2 24 puts: $765Q2 24P/C 0.04
Numbers
QuarterCallsPutsP/C
Q3 2023$7.2k$3.4k0.47
Q4 2023$16.0k$1.3k0.08
Q1 2024$44.3k$1.3k0.03
Q2 2024$17.9k$7650.04

Biggest buyers

Bain Capital Life Sciences Investors, LLC New +5,410,361+5.4m
Boxer Capital, LLC Added +3,151,603+3.2m
Casdin Capital, LLC Added +1,984,126+2.0m
Venrock Adviser, LLC Added +1,984,126+2.0m
BlackRock Inc. Added +1,397,432+1.4m
ADAGE CAPITAL PARTNERS GP, L.L.C. New +1,322,751+1.3m
Syncona Portfolio Ltd New +1,000,771+1.0m
Octagon Capital Advisors LP Added +793,650+793.6k
VANGUARD GROUP INC Added +593,480+593.5k
GEODE CAPITAL MANAGEMENT, LLC Added +424,977+425.0k

Biggest sellers

Avidity Partners Management LP Sold out -1,221,555-1.2m
FMR LLC Reduced -420,949-420.9k
MORGAN STANLEY Reduced -414,527-414.5k
FEDERATED HERMES, INC. Reduced -338,980-339.0k
JACOBS LEVY EQUITY MANAGEMENT, INC Reduced -283,358-283.4k
Schonfeld Strategic Advisors LLC Sold out -93,085-93.1k
Jump Financial, LLC Sold out -22,330-22.3k
Cubist Systematic Strategies, LLC Sold out -18,907-18.9k
UBS Group AG Reduced -14,623-14.6k
OCCUDO QUANTITATIVE STRATEGIES LP Sold out -13,562-13.6k

Biggest calls

CITADEL ADVISORS LLC Reduced $17.9k7.0k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

CITADEL ADVISORS LLC Unchanged $765300 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
RA CAPITAL MANAGEMENT, L.P. 13G · passive investor new · filed 2026-01-16 9.9% new 17.9m≈ $44.0m 2026-01-16
TCG Crossover GP II, LLC 13G · passive investor new · filed 2026-01-15 9.9% new 17.8m≈ $43.5m 2026-01-15
Deep Track Capital, LP 13G · passive investor new · filed 2026-01-15 7.3% new 13.5m≈ $33.0m 2026-01-15
RTW INVESTMENTS, LP 13G · institution new · filed 2026-05-15 7.1% new 13.0m≈ $32.0m 2026-05-15
Venrock Healthcare Capital Partners III, L.P. 13G · passive investor +2.4 pts · filed 2026-01-16 7.1% +2.4 pts 13.0m≈ $32.0m 2026-01-16
Commodore Capital LP 13G · passive investor new · filed 2026-01-16 7.1% new 13.0m≈ $32.0m 2026-01-16

Fell to 5% or below in the last year: Point72 Asset Management, L.P. (3.3%, 2026-05-15), Bain Capital Life Sciences Opportunities III, LP (4.1%, 2025-11-14)

Insider purchases and sales in Q2 2024

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
404Q3 22: 0 buyingQ3 22: 0 sellingQ4 22: 0 buyingQ4 22: 0 sellingQ4 22Q1 23: 0 buyingQ1 23: 1 sellingQ2 23: 0 buyingQ2 23: 0 sellingQ2 23Q3 23: 0 buyingQ3 23: 0 sellingQ4 23: 0 buyingQ4 23: 0 sellingQ4 23Q1 24: 0 buyingQ1 24: 2 sellingQ2 24: 0 buyingQ2 24: 3 sellingQ2 24
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20220—0——
Q4 20220—0——
Q1 20230—1$539.6k—
Q2 20230—0——
Q3 20230—0——
Q4 20230—0——
Q1 20240—2$292.7k—
Q2 20240—3$78.9k$75.3k
DateInsiderTradeSharesPrice ValueTheir holding
2024-06-20 Russotti Gregory Officer Sold plan 5,000 $2.84 $14.2k5.0k shares -2%
2024-06-05 Russotti Gregory Officer Sold plan 5,000 $3.00 $15.0k5.0k shares -2%
2024-05-20 Russotti Gregory Officer Sold plan 5,000 $3.00 $15.0k5.0k shares -2%
2024-05-06 Russotti Gregory Officer Sold plan 5,000 $3.12 $15.6k5.0k shares -2%
2024-05-03 Farid Adrienne Chief Operations Officer Sold 913 $3.11 $2.8k913 shares -1%
2024-05-03 Carr Douglas SVP Finance & Operations Sold 257 $3.11 $799257 shares -<1%
2024-04-22 Russotti Gregory Officer Sold plan 5,000 $3.10 $15.5k5.0k shares -2%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Bain Capital Life Sciences Investors, LLC 1.51% of their portfolio Boston, MA 5,410,3615.4m $13.8m $13.8m 1.51% New
2 Venrock Adviser, LLC 0.88% of their portfolio NEW YORK, NY 5,389,2595.4m $13.7m $13.7m 0.88% Added +2.0m +1,984,126
3 Casdin Capital, LLC 1.01% of their portfolio New York, NY 5,190,5065.2m $13.2m $13.2m 1.01% Added +2.0m +1,984,126
4 Boxer Capital, LLC 0.66% of their portfolio San Diego, CA 4,901,6034.9m $12.5m $12.5m 0.66% Added +3.2m +3,151,603
5 FMR LLC 0.00% of their portfolio BOSTON, MA 2,950,2793.0m $7.5m $7.5m 0.00% Reduced -420.9k -420,949
6 BlackRock Inc. 0.00% of their portfolio New York, NY 2,895,6132.9m $7.4m $7.4m 0.00% Added +1.4m +1,397,432
7 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 1,732,1331.7m $4.4m $4.4m 0.00% Added +593.5k +593,480
8 DAFNA Capital Management LLC 1.04% of their portfolio LOS ANGELES, CA 1,704,2321.7m $4.3m $4.3m 1.04% Added +396.8k +396,825
9 Octagon Capital Advisors LP 0.56% of their portfolio NEW YORK, NY 1,333,6501.3m $3.4m $3.4m 0.56% Added +793.6k +793,650
10 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio Boston, MA 1,322,7511.3m $3.4m $3.4m 0.01% New
11 Syncona Portfolio Ltd 2.97% of their portfolio St Peter Port, Guernsey, X0 1,000,7711.0m $2.6m $2.6m 2.97% New
12 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 935,568935.6k $2.4m $2.4m 0.00% Added +425.0k +424,977
13 TANG CAPITAL MANAGEMENT LLC 0.23% of their portfolio SAN DIEGO, CA 900,000900.0k $2.3m $2.3m 0.23% Unchanged
14 BAKER BROS. ADVISORS LP 0.03% of their portfolio NEW YORK, NY 797,460797.5k $2.0m $2.0m 0.03% Unchanged
15 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 779,591779.6k $2.0m $2.0m 0.00% Added +294.4k +294,373
16 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 398,380398.4k $1.0m $1.0m 0.00% Added +246.3k +246,329
17 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 378,633378.6k $965.5k $965.5k 0.00% Added +21.2k +21,232
18 FEDERATED HERMES, INC. 0.00% of their portfolio PITTSBURGH, PA 276,163276.2k $704.2k $704.2k 0.00% Reduced -339.0k -338,980
19 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 228,613228.6k $583.0k $583.0k 0.00% Reduced -414.5k -414,527
20 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 211,326211.3k $538.9k $538.9k 0.00% Added +26.7k +26,711
21 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 165,500165.5k $422.0k $422.0k 0.00% Added +9.5k +9,500
22 BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio HOUSTON, TX 157,600157.6k $401.9k $401.9k 0.01% Added +40.0k +40,000
23 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 149,000149.0k $380.0k $380.0k 0.00% Added +78.1k +78,088
24 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 105,650105.7k $269.4k $269.4k 0.00% Added +45.6k +45,611
25 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 80,63280.6k $205.6k $205.6k 0.00% Added +68.4k +68,422
26 WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio PLYMOUTH, MN 78,23478.2k $199.5k $199.5k 0.00% Added +19 +19
27 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 75,31575.3k $192.0k $192.0k 0.00% Added +44.2k +44,155
28 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 70,80670.8k $180.6k $180.6k 0.00% Added +31.5k +31,523
29 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 52,46652.5k $133.8k $133.8k 0.00% Added +18.8k +18,828
30 CORNERCAP INVESTMENT COUNSEL INC 0.02% of their portfolio Atlanta, GA 51,01551.0k $130.1k $130.1k 0.02% Reduced -505 -505
31 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 45,16045.2k $115.2k $115.2k 0.00% Reduced -9.1k -9,132
32 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 40,11440.1k $102.3k $102.3k 0.00% Reduced -11.2k -11,246
33 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 29,59829.6k $75.5k $75.5k 0.00% Reduced -12.7k -12,745
34 HarbourVest Partners LLC 0.04% of their portfolio Boston, MA 29,01829.0k $74.0k $74.0k 0.04% Unchanged
35 Parametrica Management Ltd 0.09% of their portfolio WANCHAI, K3 27,84027.8k $71.0k $71.0k 0.09% Unchanged
36 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 24,68324.7k $62.9k $62.9k 0.00% First filing
37 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 20,15820.2k $51.4k $51.4k 0.00% Added +11.9k +11,895
38 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 20,02020.0k $51.1k $51.1k 0.00% Added +8.4k +8,440
39 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 17,43717.4k $44.5k $44.5k 0.00% New
40 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 17,03217.0k $43.4k $43.4k 0.00% Added +12.7k +12,676
41 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 16,14816.1k $41.2k $41.2k 0.00% Reduced -315 -315
42 PRUDENTIAL FINANCIAL INC 0.00% of their portfolio NEWARK, NJ 15,15015.2k $38.6k $38.6k 0.00% Added +3.3k +3,330
43 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 14,88214.9k $38.0k $38.0k 0.00% New
44 UBS Group AG 0.00% of their portfolio ZURICH, V8 14,09514.1k $35.9k $35.9k 0.00% Reduced -14.6k -14,623
45 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 13,74313.7k $35.0k $35.0k 0.00% Unchanged
46 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 11,38911.4k $29.0k $29.0k 0.00% First filing
47 JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio FLORHAM PARK, NJ 10,58310.6k $27.0k $27.0k 0.00% Reduced -283.4k -283,358
48 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 10,51510.5k $26.8k $26.8k 0.00% Added +5.9k +5,919
49 FOUNDERS FINANCIAL SECURITIES LLC 0.00% of their portfolio TOWSON, MD 10,00010.0k $25.5k $25.5k 0.00% Unchanged
50 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 7,2617.3k $18.5k $18.5k 0.00% Reduced -2.5k -2,473
51 Russell Investments Group, Ltd. 0.00% of their portfolio Seattle, WA 5,8425.8k $14.9k $14.9k 0.00% Added +3.0k +2,990
52 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 4,3154.3k $11.0k $11.0k 0.00% Added +2.8k +2,842
53 Legal & General Group Plc 0.00% of their portfolio London, X0 3,9764.0k $10.1k $10.1k 0.00% Added +1.9k +1,863
54 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 3,3243.3k $8.5k $8.5k 0.00% Added +969 +969
55 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 905905 $2.3k $2.3k 0.00% Unchanged
56 NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio ST. LOUIS, MO 711711 $1.8k $1.8k 0.00% Added +600 +600
57 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 706706 $2.0k $2.0k 0.00% Unchanged
58 GAMMA Investing LLC 0.00% of their portfolio FOSTER CITY, CA 176176 $449 $449 0.00% Reduced -119 -119
59 PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio COLUMBUS, OH 100100 $255 $255 0.00% Reduced -4.2k -4,241
60 SIMPLEX TRADING, LLC 0.00% of their portfolio CHICAGO, IL 6868 $0 $0 0.00% Reduced -2.4k -2,352
61 CWM, LLC 0.00% of their portfolio OMAHA, NE 2626 $0 $0 0.00% Added +24 +24
62 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged