CASTLE BIOSCIENCES INC CSTL
COM · Common Stock · CUSIP 14843C105 · ISIN US14843C1053
- SectorHealth care
- IndustryServices-Medical Laboratories
- HeadquartersFriendswood, TX
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.5m this quarter). Holder counts are more reliable. Shares outstanding: 26.4m as of 2022-10-26, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $23.54. Options: 4 managers hold calls ($946.1k notional), 3 hold puts ($152.6k).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 157 |
| Q4 2022 | 154 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $5.8m | $13.0k | 0.00 |
| Q4 2022 | $946.1k | $152.6k | 0.16 |
Biggest buyers
| PRINCIPAL FINANCIAL GROUP INC | Added | +475.1k |
| Portolan Capital Management, LLC | Added | +283.1k |
| Granahan Investment Management, LLC | Added | +282.1k |
| DEERFIELD MANAGEMENT COMPANY, L.P. | New | +272.1k |
| Point72 Asset Management, L.P. | New | +201.4k |
| Nuveen Asset Management, LLC | Added | +192.0k |
| Stonepine Capital Management, LLC | New | +178.2k |
| VANGUARD GROUP INC | Added | +142.0k |
| Polar Asset Management Partners Inc. | New | +107.1k |
| KORNITZER CAPITAL MANAGEMENT INC /KS | Added | +92.0k |
Biggest sellers
| Invesco Ltd. | Reduced | -326.9k |
| Soleus Capital Management, L.P. | Sold out | -297.8k |
| SEGALL BRYANT & HAMILL, LLC | Sold out | -202.3k |
| CITADEL ADVISORS LLC | Reduced | -181.3k |
| MORGAN STANLEY | Reduced | -137.5k |
| WASATCH ADVISORS LP | Reduced | -122.2k |
| Schonfeld Strategic Advisors LLC | Reduced | -108.9k |
| SEI INVESTMENTS CO | Sold out | -88.6k |
| Russell Investments Group, Ltd. | Sold out | -86.6k |
| CITIGROUP INC | Reduced | -83.5k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $546.1k23.2k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $371.9k15.8k shares |
| SIMPLEX TRADING, LLC | Reduced | $28.0k1.2k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $143.6k6.1k shares |
| SIMPLEX TRADING, LLC | Unchanged | $9.0k400 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| RTW INVESTMENTS, LP 13G · institution +2.1 pts · filed 2026-05-15 | 9.3% |
| BlackRock, Inc. 13G · institution filed 2025-04-23 | 8.2% |
Fell to 5% or below in the last year: Portolan Capital Management, LLC (4.5%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26), DIMENSIONAL FUND ADVISORS LP (3.9%, 2026-01-21)
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 2 | $3.9m | — |
| Q1 2022 | 0 | — | 1 | $4.8m | — |
| Q2 2022 | 1 | $24.8k | 0 | — | — |
| Q3 2022 | 0 | — | 2 | $2.4m | — |
| Q4 2022 | 1 | $25.0k | 2 | $1.8m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-12-19 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director | Sold | $44.6k1.9k shares |
| 2022-12-19 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director | Sold | $43.8k1.9k shares |
| 2022-12-19 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk | Sold | $41.8k1.8k shares |
| 2022-12-19 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold | Sold | $24.7k1.1k shares |
| 2022-12-19 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By Derek Maetzold 2020 Irrevocable Trust | Sold | $21.4k943 shares |
| 2022-12-19 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director | Sold | $8.7k372 shares |
| 2022-12-19 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold | Sold | $8.7k375 shares |
| 2022-12-19 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold | Sold | $8.7k375 shares |
| 2022-12-19 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold Descendants 2020 Trust | Sold | $4.3k189 shares |
| 2022-12-05 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director | Sold | $95.0k3.8k shares |
| 2022-12-05 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By Derek Maetzold 2020 Irrevocable Trust | Sold | $46.5k1.9k shares |
| 2022-12-05 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk | Sold | $43.4k1.8k shares |
| 2022-12-05 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director | Sold | $9.3k375 shares |
| 2022-12-05 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold | Sold | $9.3k375 shares |
| 2022-12-05 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold | Sold | $9.3k375 shares |
| 2022-12-05 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold | Sold | $9.3k375 shares |
| 2022-12-01 | BRADBURY DANIEL Director · By LLC | Sold | $184.5k7.7k shares |
| 2022-11-29 | Olson Tiffany Director | Bought | $25.0k1.2k shares |
| 2022-11-22 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director | Sold | $19.8k964 shares |
| 2022-11-22 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk | Sold | $9.7k472 shares |
| 2022-11-22 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold | Sold | $9.0k440 shares |
| 2022-11-22 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director | Sold | $3.9k188 shares |
| 2022-11-22 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold | Sold | $2.0k96 shares |
| 2022-11-22 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold | Sold | $1.9k94 shares |
| 2022-11-21 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director | Sold | $59.8k2.9k shares |
| 2022-11-21 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By Derek Maetzold 2020 Irrevocable Trust | Sold | $29.2k1.4k shares |
| 2022-11-21 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk | Sold | $27.3k1.3k shares |
| 2022-11-21 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold Descendants 2020 Trust | Sold | $5.9k281 shares |
| 2022-11-21 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold | Sold | $5.9k281 shares |
| 2022-11-21 | MAETZOLD DEREK J Pres. & Chief Exec. Officer, director · By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold | Sold | $5.9k281 shares |
The latest 30 of 83 trades.
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| WASATCH ADVISORS LP 0.51% of their portfolio | 3.2m $75.9m | Reduced -122.2k |
| BlackRock Inc. 0.00% of their portfolio | 2.1m $50.0m | Added +81.9k |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.4m $32.8m | Added +142.0k |
| Granahan Investment Management, LLC 0.75% of their portfolio | 1.0m $24.6m | Added +282.1k |
| Bellevue Group AG 0.30% of their portfolio | 944.3k $22.2m | Added +2.4k |
| MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio | 913.4k $21.5m | Reduced -49.0k |
| PRINCIPAL FINANCIAL GROUP INC 0.02% of their portfolio | 910.8k $21.4m | Added +475.1k |
| KORNITZER CAPITAL MANAGEMENT INC /KS 0.34% of their portfolio | 716.2k $16.9m | Added +92.0k |
| Portolan Capital Management, LLC 1.36% of their portfolio | 583.7k $13.7m | Added +283.1k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 551.3k $13.0m | Reduced -181.3k |
| PALISADE CAPITAL MANAGEMENT, LP 0.35% of their portfolio | 551.1k $13.0m | Reduced -28.8k |
| RTW INVESTMENTS, LP 0.25% of their portfolio | 517.0k $12.2m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 504.5k $11.9m | Added +6.5k |
| Greenhouse Funds LLLP 1.07% of their portfolio | 494.2k $11.6m | Added +51.0k |
| GW&K Investment Management, LLC 0.11% of their portfolio | 479.7k $11.3m | Reduced -24.4k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 465.7k $11.0m | Added +20.0k |
| ESSEX INVESTMENT MANAGEMENT CO LLC 1.66% of their portfolio | 453.3k $10.7m | Added +16.7k |
| INTRINSIC EDGE CAPITAL MANAGEMENT LLC 0.92% of their portfolio | 365.0k $8.6m | Added +52.6k |
| Allspring Global Investments Holdings, LLC 0.01% of their portfolio | 352.8k $8.3m | Added +588 |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 323.7k $7.6m | Added +85.2k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 302.6k $7.1m | Added +192.0k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.13% of their portfolio | 272.1k $6.4m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 246.9k $5.8m | Added +64.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 230.1k $5.4m | Added +2.6k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.01% of their portfolio | 214.5k $5.0m | Added +9.2k |
| BANQUE PICTET & CIE SA 0.05% of their portfolio | 204.4k $4.8m | Reduced -43.3k |
| Point72 Asset Management, L.P. 0.02% of their portfolio | 201.4k $4.7m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 184.5k $4.3m | Added +6.9k |
| Stonepine Capital Management, LLC 1.77% of their portfolio | 178.2k $4.2m | New |
| Monarch Partners Asset Management LLC 1.18% of their portfolio | 170.2k $4.0m | Reduced -18.4k |
| TRUSTCORE FINANCIAL SERVICES, LLC 0.34% of their portfolio | 164.9k $3.9m | Added +146 |
| First Light Asset Management, LLC 0.35% of their portfolio | 161.6k $3.8m | Reduced -1.6k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 159.1k $3.7m | Added +12.7k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 132.1k $3.1m | Reduced -21.3k |
| NORGES BANK 0.00% of their portfolio | 131.2k $3.1m | Reduced -5.4k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 111.2k $2.6m | Reduced -21.3k |
| Polar Asset Management Partners Inc. 0.04% of their portfolio | 107.1k $2.5m | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 104.6k $2.5m | Added +39.6k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 83.0k $2.0m | Added +2.0k |
| ALGERT GLOBAL LLC 0.09% of their portfolio | 68.9k $1.6m | Added +18.9k |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.01% of their portfolio | 66.7k $1.6m | Reduced -12.1k |
| TUDOR INVESTMENT CORP ET AL 0.03% of their portfolio | 58.9k $1.4m | Added +44.7k |
| MORGAN STANLEY 0.00% of their portfolio | 58.3k $1.4m | Reduced -137.5k |
| ISTHMUS PARTNERS, LLC 0.20% of their portfolio | 57.8k $1.4m | Added +1.2k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 57.5k $1.4m | Reduced -108.9k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 53.9k $1.3m | Reduced -67.6k |
| Swiss National Bank 0.00% of their portfolio | 53.9k $1.3m | Added +1.0k |
| STEPHENS INC /AR/ 0.03% of their portfolio | 53.6k $1.3m | Added +8.9k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 49.0k $1.2m | Reduced -76.1k |
| ZACKS INVESTMENT MANAGEMENT 0.01% of their portfolio | 42.5k $1.0m | New |
| Engineers Gate Manager LP 0.06% of their portfolio | 39.5k $930.5k | Added +30.0k |
| Premier Fund Managers Ltd 0.03% of their portfolio | 38.5k $892.0k | Reduced -13.8k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 37.9k $892.0k | Added +393 |
| Candriam S.C.A. 0.01% of their portfolio | 37.6k $884.9k | Added +3.2k |
| KING LUTHER CAPITAL MANAGEMENT CORP 0.00% of their portfolio | 36.3k $854.6k | Reduced -9.5k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 35.4k $833.0k | Added +2.4k |
| ABG Innovation Capital Partners III GP Ltd 60.43% of their portfolio | 33.6k $791.6k | Unchanged |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 33.4k $787.0k | Reduced -20.2k |
| Orion Porfolio Solutions, LLC 0.02% of their portfolio | 32.8k $772.7k | Reduced -3.6k |
| Advisors Capital Management, LLC 0.02% of their portfolio | 31.2k $735.0k | Added +4.3k |
| PERKINS CAPITAL MANAGEMENT INC 0.77% of their portfolio | 31.1k $732.0k | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 29.2k $687.9k | Added +323 |
| Bridgewater Associates, LP 0.00% of their portfolio | 29.2k $686.6k | Reduced -8.6k |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 28.9k $681.2k | Added +1.4k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 28.1k $662.5k | Added +5.1k |
| Graham Capital Management, L.P. 0.02% of their portfolio | 26.9k $634.0k | Reduced -17.9k |
| GSA CAPITAL PARTNERS LLP 0.08% of their portfolio | 26.9k $633.0k | Reduced -38.4k |
| SIMON QUICK ADVISORS, LLC 0.07% of their portfolio | 26.0k $612.0k | Unchanged |
| Knights of Columbus Asset Advisors LLC 0.06% of their portfolio | 25.8k $607.1k | Reduced -273 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 24.1k $566.9k | Added +20.0k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 23.2k $545.5k | Added +7.2k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.03% of their portfolio | 23.1k $544.8k | Unchanged |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 22.5k $529.6k | Unchanged |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 22.4k $527.1k | Reduced -254 |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 22.1k $520.0k | Added +5.1k |
| Parallel Advisors, LLC 0.02% of their portfolio | 22.1k $519.5k | Reduced -22 |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 21.6k $509.3k | Reduced -229 |
| Covenant Partners, LLC 0.20% of their portfolio | 21.3k $500.9k | Unchanged |
| Yu Fan 6.49% of their portfolio | 20.6k $484.7k | Unchanged |
| STRS OHIO 0.00% of their portfolio | 20.4k $480.0k | Unchanged |
| SIGNATUREFD, LLC 0.01% of their portfolio | 19.4k $456.6k | Unchanged |
| Jump Financial, LLC 0.02% of their portfolio | 19.3k $454.3k | Reduced -1.0k |
| Invesco Ltd. 0.00% of their portfolio | 19.1k $450.2k | Reduced -326.9k |
| OCCUDO QUANTITATIVE STRATEGIES LP 0.05% of their portfolio | 19.1k $448.6k | Reduced -3.3k |
| Legato Capital Management LLC 0.08% of their portfolio | 18.5k $435.4k | New |
| Capital Impact Advisors, LLC 0.36% of their portfolio | 15.5k $363.7k | Added +997 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 15.0k $353.0k | Reduced -1.6k |
| Squarepoint Ops LLC 0.00% of their portfolio | 13.7k $322.5k | Reduced -41.2k |
| Polar Capital Holdings Plc 0.00% of their portfolio | 13.4k $315.4k | Reduced -35.6k |
| Bank Pictet & Cie (Europe) AG 0.01% of their portfolio | 12.6k $297.0k | Reduced -3.3k |
| Cambridge Investment Research Advisors, Inc. 0.00% of their portfolio | 12.5k $294.0k | Reduced -501 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 12.4k $291.2k | Unchanged |
| Baird Financial Group, Inc. 0.00% of their portfolio | 12.2k $287.0k | Reduced -155 |
| TOWNSQUARE CAPITAL LLC 0.01% of their portfolio | 12.2k $286.2k | New |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 11.6k $273.2k | Reduced -42 |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 11.5k $269.9k | New |
| Versor Investments LP 0.02% of their portfolio | 11.3k $265.4k | Added +2.3k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 11.0k $257.9k | Reduced -5.5k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 10.9k $257.3k | Added +11 |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 10.9k $256.5k | Added +162 |