CASSAVA SCIENCES INC FLNA
COM · Common Stock · CUSIP 14817C107 · ISIN US14817C1071
American pharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersAustin, TX
- Founded1998
- Websitecassavasciences.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 43.2m as of 2024-02-26, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $20.30. Options: 17 managers hold calls ($46.0m notional), 17 hold puts ($32.9m).
Trends to Q1 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 174 |
| Q4 2022 | 152 |
| Q1 2023 | 145 |
| Q2 2023 | 152 |
| Q3 2023 | 141 |
| Q4 2023 | 153 |
| Q1 2024 | 142 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 70 | 78 |
| Q1 2023 | 76 | 50 |
| Q2 2023 | 62 | 55 |
| Q3 2023 | 69 | 57 |
| Q4 2023 | 68 | 56 |
| Q1 2024 | 59 | 68 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2023 | $44.4m | $41.4m | 0.93 |
| Q3 2023 | $65.2m | $58.7m | 0.90 |
| Q4 2023 | $81.5m | $56.7m | 0.70 |
| Q1 2024 | $46.0m | $32.9m | 0.71 |
Biggest buyers
| VANGUARD GROUP INC | Added | +31.9k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +27.8k |
| WOLVERINE TRADING, LLC | New | +26.6k |
| STATE STREET CORP | Added | +23.8k |
| PFG Investments, LLC | New | +21.9k |
| Cetera Investment Advisers | New | +19.8k |
| Advisory Services Network, LLC | Added | +19.3k |
| Essex LLC | Added | +15.9k |
| DIMENSIONAL FUND ADVISORS LP | Added | +12.3k |
| Empirical Asset Management, LLC | New | +10.0k |
Biggest sellers
| COWEN AND COMPANY, LLC | Sold out | -500.0k |
| MORGAN STANLEY | Reduced | -469.3k |
| JANE STREET GROUP, LLC | Reduced | -277.8k |
| NATIONAL BANK OF CANADA /FI/ | Reduced | -259.1k |
| Nuveen Asset Management, LLC | Reduced | -116.3k |
| GOLDMAN SACHS GROUP INC | Reduced | -108.8k |
| SG Americas Securities, LLC | Sold out | -92.4k |
| BANK OF AMERICA CORP /DE/ | Reduced | -90.0k |
| Jefferies Financial Group Inc. | Reduced | -81.7k |
| MILLENNIUM MANAGEMENT LLC | Sold out | -66.9k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $10.4m514.4k shares |
| LMR Partners LLP | Reduced | $10.1m495.7k shares |
| GROUP ONE TRADING LLC | Reduced | $9.8m481.8k shares |
| NATIONAL BANK OF CANADA /FI/ | Added | $5.7m2.8k shares |
| Walleye Trading LLC | Reduced | $2.5m121.3k shares |
| JANE STREET GROUP, LLC | Reduced | $1.4m71.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $1.3m91.5k shares |
| CITADEL ADVISORS LLC | Reduced | $1.2m61.0k shares |
| GTS SECURITIES LLC | Reduced | $1.2m57.7k shares |
| Belvedere Trading LLC | Added | $793.3k39.1k shares |
Biggest puts
| JANE STREET GROUP, LLC | Added | $5.3m263.3k shares |
| NATIONAL BANK OF CANADA /FI/ | Reduced | $4.0m2.0k shares |
| LMR Partners LLP | Reduced | $4.0m195.6k shares |
| Walleye Trading LLC | Added | $3.7m183.0k shares |
| GROUP ONE TRADING LLC | Reduced | $3.7m182.8k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.9m142.5k shares |
| BANK OF AMERICA CORP /DE/ | Added | $2.6m129.4k shares |
| Jefferies Financial Group Inc. | Reduced | $2.3m114.9k shares |
| CITADEL ADVISORS LLC | Reduced | $1.3m64.7k shares |
| GTS SECURITIES LLC | Reduced | $884.6k43.6k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Insider purchases and sales in Q1 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 4 | $3.0m | 0 | — | — |
| Q4 2022 | 0 | — | 0 | — | — |
| Q1 2023 | 1 | $2.3m | 0 | — | — |
| Q2 2023 | 0 | — | 0 | — | — |
| Q3 2023 | 2 | $831.4k | 0 | — | — |
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
None reported in Q1 2024.
Holders, Q1 2024
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.00% of their portfolio | 3.0m $61.8m | Added +8.0k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.4m $47.8m | Added +31.9k |
| STATE STREET CORP 0.00% of their portfolio | 1.1m $22.2m | Added +23.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 901.8k $18.3m | Added +27.8k |
| MORGAN STANLEY 0.00% of their portfolio | 613.3k $12.4m | Reduced -469.3k |
| Gallacher Capital Management LLC 6.03% of their portfolio | 585.4k $11.9m | Added +3.8k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 378.8k $7.7m | Reduced -8.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 316.4k $6.4m | Added +7.6k |
| NORGES BANK 0.00% of their portfolio | 199.7k $4.1m | Reduced -16.8k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 162.2k $3.3m | Reduced -116.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 143.9k $2.9m | Reduced -90.0k |
| Clear Creek Financial Management, LLC 0.36% of their portfolio | 138.5k $2.8m | Added +3.9k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 119.3k $2.4m | Reduced -13.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 111.7k $2.3m | Added +1.5k |
| Susquehanna Portfolio Strategies, LLC 0.05% of their portfolio | 105.4k $2.1m | Reduced -5.0k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 96.4k $2.0m | Reduced -277.8k |
| UBS Group AG 0.00% of their portfolio | 84.7k $1.7m | Added +890 |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 82.5k $1.7m | Reduced -35.7k |
| Swiss National Bank 0.00% of their portfolio | 78.6k $1.6m | Unchanged |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 76.0k $1.5m | Added +1.9k |
| LPL Financial LLC 0.00% of their portfolio | 57.7k $1.2m | Added +1.7k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 56.9k $1.2m | Added +835 |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 52.8k $1.1m | Reduced -108.8k |
| BARCLAYS PLC 0.00% of their portfolio | 51.4k $1.0m | Reduced -54.2k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 51.2k $1.0m | Added +1.2k |
| Essex LLC 0.24% of their portfolio | 50.7k $1.0m | Added +15.9k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 46.3k $939.0k | Unchanged |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 45.1k $914.0k | Added +2.9k |
| Legal & General Group Plc 0.00% of their portfolio | 42.0k $852.6k | Added +1.2k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 40.1k $814.3k | Reduced -1.9k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 38.2k $775.1k | Unchanged |
| Advisory Services Network, LLC 0.01% of their portfolio | 33.2k $673.6k | Added +19.3k |
| Sculptor Capital LP 0.01% of their portfolio | 32.3k $654.8k | Reduced -18.0k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 31.3k $636.0k | Added +1.5k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 29.7k $601.7k | Added +12.3k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 27.4k $556.4k | Reduced -30.1k |
| WOLVERINE TRADING, LLC 0.01% of their portfolio | 26.6k $539.6k | New |
| Hennion & Walsh Asset Management, Inc. 0.03% of their portfolio | 25.1k $509.1k | Added +3.2k |
| PFG Investments, LLC 0.03% of their portfolio | 21.9k $443.9k | New |
| CITIGROUP INC 0.00% of their portfolio | 21.8k $442.8k | Added +963 |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 21.5k $436.0k | Added +342 |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 20.9k $423.8k | Added +1.8k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 20.4k $414.4k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 20.3k $412.4k | Added +5.1k |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 19.8k $402.3k | Added +60 |
| Cetera Investment Advisers 0.00% of their portfolio | 19.8k $401.4k | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 19.1k $388.4k | Reduced -27 |
| Brookstone Capital Management 0.01% of their portfolio | 16.8k $339.9k | Unchanged |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 16.6k $337.6k | Added +1 |
| IMC-Chicago, LLC 0.01% of their portfolio | 16.5k $334.5k | Reduced -1.2k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 16.5k $386.5k | Reduced -1.4k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 16.5k $333.9k | Reduced -645 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 16.4k $331.8k | Added +2.2k |
| Jefferies Financial Group Inc. 0.01% of their portfolio | 15.8k $321.0k | Reduced -81.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 15.7k $318.3k | Reduced -1.5k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 15.6k $317.3k | Reduced -9 |
| Janney Montgomery Scott LLC 0.00% of their portfolio | 14.7k $298.0k | Added +506 |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 14.5k $295.1k | Reduced -734 |
| Invesco Ltd. 0.00% of their portfolio | 14.2k $288.5k | Reduced -61.3k |
| FIFTH THIRD BANCORP 0.00% of their portfolio | 14.1k $286.5k | Unchanged |
| IVC Wealth Advisors LLC 0.16% of their portfolio | 13.4k $271.3k | Unchanged |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 13.2k $266.9k | Reduced -2.6k |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 12.8k $260.7k | Added +1.1k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 12.1k $293.0k | Added +650 |
| FMR LLC 0.00% of their portfolio | 11.8k $239.2k | Added +9.8k |
| Cutler Group LLC / CA 0.12% of their portfolio | 11.7k $237.0k | Reduced -19.8k |
| Apollon Wealth Management, LLC 0.01% of their portfolio | 11.6k $234.6k | Added +890 |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 11.0k $223.7k | Reduced -120 |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 11.0k $222.5k | Added +355 |
| STRS OHIO 0.00% of their portfolio | 10.7k $217.0k | Reduced -1.3k |
| Empirical Asset Management, LLC 0.10% of their portfolio | 10.0k $202.9k | New |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 10.0k $202.3k | New |
| SIMPLEX TRADING, LLC 0.01% of their portfolio | 9.9k $201.0k | Added +9.1k |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 9.4k $191.0k | Added +5.6k |
| LANARK FINANCIAL, INC. 0.01% of their portfolio | 7.7k $155.0k | Added +650 |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 7.5k $151.5k | Added +1.8k |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 0.00% of their portfolio | 5.4k $109.0k | Unchanged |
| NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio | 5.2k $105.2k | Reduced -259.1k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 4.7k $95.2k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 4.5k $90.0k | Reduced -10.9k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 4.3k $87.3k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 4.0k $80.2k | Unchanged |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 3.7k $75.0k | Added +700 |
| Byrne Asset Management LLC 0.05% of their portfolio | 3.6k $73.5k | Added +270 |
| US BANCORP \DE\ 0.00% of their portfolio | 2.9k $58.9k | Reduced -128 |
| VIRTUS ADVISERS, LLC 0.03% of their portfolio | 2.9k $58.4k | Reduced -196 |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 2.4k $49.6k | Unchanged |
| EntryPoint Capital, LLC 0.04% of their portfolio | 2.3k $46.6k | Added +2.1k |
| Metropolitan Life Insurance Co/NY 0.00% of their portfolio | 2.3k $46.2k | Unchanged |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 2.1k $43.4k | Reduced -20 |
| MONTAG A & ASSOCIATES INC 0.00% of their portfolio | 1.5k $30.4k | Unchanged |
| AMALGAMATED BANK 0.00% of their portfolio | 1.3k $27.0k | Reduced -4.3k |
| AlphaQuest LLC 0.00% of their portfolio | 1.3k $26.9k | Reduced -3.9k |
| HARBOUR INVESTMENTS, INC. 0.00% of their portfolio | 1.1k $21.5k | Unchanged |
| Sandy Spring Bank 0.00% of their portfolio | 1.1k $21.3k | Added +1.0k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.0k $20.9k | Reduced -7.5k |
| SITTNER & NELSON, LLC 0.01% of their portfolio | 800 $16.2k | Unchanged |
| Belvedere Trading LLC 0.00% of their portfolio | 787 $16.0k | Reduced -322 |
| GoalVest Advisory LLC 0.01% of their portfolio | 746 $15.1k | Unchanged |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 584 $11.8k | Added +26 |