CASSAVA SCIENCES INC FLNA
COM · Common Stock · CUSIP 14817C107 · ISIN US14817C1071
American pharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersAustin, TX
- Founded1998
- Websitecassavasciences.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 40.1m as of 2022-11-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $29.55. Options: 21 managers hold calls ($132.6m notional), 20 hold puts ($104.5m).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 174 |
| Q4 2022 | 152 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $277.0m | $173.0m | 0.62 |
| Q4 2022 | $132.6m | $104.5m | 0.79 |
Biggest buyers
| Invesco Ltd. | Added | +164.2k |
| GROUP ONE TRADING LLC | New | +104.5k |
| VANGUARD GROUP INC | Added | +87.1k |
| GOLDMAN SACHS GROUP INC | Added | +82.5k |
| Nuveen Asset Management, LLC | Added | +80.9k |
| BlackRock Inc. | Added | +78.8k |
| IMC-Chicago, LLC | New | +62.1k |
| OSAIC HOLDINGS, INC. | Added | +56.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | +51.9k |
| Clear Creek Financial Management, LLC | Added | +51.4k |
Biggest sellers
| BANK OF AMERICA CORP /DE/ | Reduced | -165.0k |
| MARSHALL WACE, LLP | Sold out | -157.3k |
| BNP PARIBAS FINANCIAL MARKETS | Reduced | -123.5k |
| GMT Capital Corp | Sold out | -115.1k |
| Think Investments LP | Sold out | -111.7k |
| Cetera Advisor Networks LLC | Sold out | -31.9k |
| KESTRA PRIVATE WEALTH SERVICES, LLC | Sold out | -31.5k |
| Squarepoint Ops LLC | Sold out | -21.0k |
| NATIONAL BANK OF CANADA /FI/ | Reduced | -19.8k |
| COWEN AND COMPANY, LLC | Sold out | -19.5k |
Biggest calls
| GROUP ONE TRADING LLC | Reduced | $31.1m1.1m shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $27.3m924.3k shares |
| CITADEL ADVISORS LLC | Reduced | $21.3m720.7k shares |
| SIMPLEX TRADING, LLC | Added | $14.9m505.7k shares |
| JANE STREET GROUP, LLC | Reduced | $9.0m304.1k shares |
| Jefferies Financial Group Inc. | New | $4.9m164.8k shares |
| IMC-Chicago, LLC | Reduced | $4.7m159.3k shares |
| Tri Locum Partners LP | Reduced | $3.8m127.2k shares |
| Parallax Volatility Advisers, L.P. | Added | $3.5m117.4k shares |
| NATIONAL BANK OF CANADA /FI/ | New | $2.9m967 shares |
Biggest puts
| Jefferies Financial Group Inc. | New | $23.9m810.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $19.5m661.2k shares |
| GROUP ONE TRADING LLC | Reduced | $15.3m519.6k shares |
| CITADEL ADVISORS LLC | Reduced | $14.4m486.7k shares |
| SIMPLEX TRADING, LLC | Reduced | $6.1m208.0k shares |
| JANE STREET GROUP, LLC | Reduced | $4.5m152.2k shares |
| PERCEPTIVE ADVISORS LLC | New | $4.4m150.0k shares |
| IMC-Chicago, LLC | Reduced | $3.8m130.1k shares |
| Parallax Volatility Advisers, L.P. | Unchanged | $2.2m74.1k shares |
| BANK OF AMERICA CORP /DE/ | Reduced | $2.2m72.8k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 0 | — | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 4 | $3.0m | 0 | — | — |
| Q4 2022 | 0 | — | 0 | — | — |
None reported in Q4 2022.
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.00% of their portfolio | 2.6m $75.8m | Added +78.8k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.2m $64.9m | Added +87.1k |
| STATE STREET CORP 0.00% of their portfolio | 994.0k $29.4m | Reduced -3.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 708.8k $20.9m | Added +23.9k |
| Gallacher Capital Management LLC 10.52% of their portfolio | 588.5k $17.4m | First filing |
| Invesco Ltd. 0.00% of their portfolio | 420.3k $12.4m | Added +164.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 352.5k $10.4m | Reduced -394 |
| NORGES BANK 0.00% of their portfolio | 330.0k $9.7m | Added +36.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 280.1k $8.3m | Added +5.2k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 235.2k $6.9m | Added +80.9k |
| MORGAN STANLEY 0.00% of their portfolio | 215.4k $6.4m | Reduced -2.5k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 159.2k $4.7m | Added +82.5k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 129.7k $3.8m | Added +856 |
| GROUP ONE TRADING LLC 0.10% of their portfolio | 104.5k $3.1m | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 101.0k $3.0m | Reduced -165.0k |
| OSAIC HOLDINGS, INC. 0.01% of their portfolio | 95.2k $2.8m | Added +56.7k |
| Swiss National Bank 0.00% of their portfolio | 91.9k $2.7m | Added +2.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 79.9k $2.4m | Added +51.9k |
| Sculptor Capital LP 0.04% of their portfolio | 71.5k $2.1m | Reduced -4.0k |
| Clear Creek Financial Management, LLC 0.44% of their portfolio | 67.3k $2.0m | Added +51.4k |
| IMC-Chicago, LLC 0.40% of their portfolio | 62.1k $1.8m | New |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 61.1k $1.8m | Added +2.4k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 51.8k $1.5m | Added +365 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 48.3k $1.4m | Added +521 |
| NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio | 48.1k $1.4m | Added +45 |
| BARCLAYS PLC 0.00% of their portfolio | 43.7k $1.3m | First filing |
| LPL Financial LLC 0.00% of their portfolio | 42.3k $1.2m | Added +2.3k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 42.0k $1.2m | Added +8.3k |
| UBS Group AG 0.00% of their portfolio | 41.6k $1.2m | Added +11.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 39.4k $1.2m | Added +4.2k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 38.2k $1.1m | Unchanged |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 38.1k $1.1m | Reduced -448 |
| Jefferies Financial Group Inc. 0.02% of their portfolio | 38.0k $1.1m | New |
| SG Americas Securities, LLC 0.02% of their portfolio | 35.4k $1.0m | Added +30.3k |
| Legal & General Group Plc 0.00% of their portfolio | 34.6k $1.0m | Reduced -143 |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 32.2k $952.2k | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 31.7k $937.5k | Added +3.0k |
| ALPS ADVISORS INC 0.01% of their portfolio | 28.3k $836.2k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 27.6k $815.7k | Added +14 |
| Parallax Volatility Advisers, L.P. 0.02% of their portfolio | 25.8k $760.9k | Reduced -2.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 25.4k $750.0k | Reduced -2.4k |
| INTREPID FAMILY OFFICE LLC 1.87% of their portfolio | 25.0k $723.2k | Unchanged |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 23.5k $692.0k | Added +7.0k |
| Cutler Group LLC / CA 0.08% of their portfolio | 22.7k $670.0k | Added +1.5k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 21.4k $633.6k | Added +2.0k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 20.9k $617.0k | Added +11.9k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 19.7k $583.1k | Reduced -981 |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 18.0k $533.0k | Reduced -66 |
| TWINBEECH CAPITAL LP 0.01% of their portfolio | 18.0k $530.5k | New |
| Hennion & Walsh Asset Management, Inc. 0.03% of their portfolio | 16.8k $496.0k | New |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 16.5k $486.7k | Unchanged |
| IVC Wealth Advisors LLC 0.33% of their portfolio | 15.3k $451.9k | Added +483 |
| Essex LLC 0.14% of their portfolio | 15.2k $449.0k | Reduced -7.5k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 14.9k $438.9k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 14.8k $436.4k | Reduced -170 |
| FIFTH THIRD BANCORP 0.00% of their portfolio | 14.1k $417.1k | Added +8.2k |
| Cambridge Investment Research Advisors, Inc. 0.00% of their portfolio | 13.5k $398.0k | Reduced -1.1k |
| CITIGROUP INC 0.00% of their portfolio | 13.3k $393.8k | Reduced -1.5k |
| Janney Montgomery Scott LLC 0.00% of their portfolio | 13.3k $392.0k | Reduced -31 |
| Creative Planning 0.00% of their portfolio | 13.0k $383.3k | Reduced -149 |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 12.8k $379.0k | Added +2.6k |
| Baird Financial Group, Inc. 0.00% of their portfolio | 12.4k $366.0k | Reduced -257 |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 12.1k $358.9k | Reduced -3.7k |
| Advisory Services Network, LLC 0.01% of their portfolio | 10.9k $320.6k | Added +5.8k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 10.8k $317.7k | Added +573 |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 10.7k $317.5k | Added +402 |
| Harvest Investment Services, LLC 0.33% of their portfolio | 10.5k $311.1k | New |
| Virtu Financial LLC 0.04% of their portfolio | 10.0k $297.0k | Reduced -3.1k |
| Handelsbanken Fonder AB 0.00% of their portfolio | 9.3k $275.0k | Reduced -700 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 9.2k $273.0k | Added +4.9k |
| Raymond James Financial Services Advisors, Inc. 0.00% of their portfolio | 9.2k $271.4k | Added +917 |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 8.8k $261.0k | Reduced -14.1k |
| US BANCORP \DE\ 0.00% of their portfolio | 8.2k $243.1k | Added +1.5k |
| STRS OHIO 0.00% of their portfolio | 8.1k $239.0k | Unchanged |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 7.7k $228.1k | Added +875 |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 7.6k $225.9k | Added +163 |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 7.5k $222.4k | Unchanged |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 7.5k $221.0k | Added +370 |
| CCG WEALTH MANAGEMENT, LLC 0.12% of their portfolio | 7.4k $217.6k | Reduced -2.5k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 7.3k $215.5k | Unchanged |
| Apollon Wealth Management, LLC 0.01% of their portfolio | 7.1k $209.2k | Reduced -117 |
| Kestra Advisory Services, LLC 0.00% of their portfolio | 6.9k $204.3k | New |
| MAI Capital Management 0.00% of their portfolio | 6.8k $200.3k | New |
| Darwin Wealth Management, LLC 0.06% of their portfolio | 6.3k $214.0k | Unchanged |
| AMALGAMATED BANK 0.00% of their portfolio | 6.1k $181.0k | Unchanged |
| McAdam, LLC 0.03% of their portfolio | 6.1k $267.0k | Reduced -82 |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 5.7k $167.2k | Reduced -123.5k |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO 0.00% of their portfolio | 5.4k $158.0k | Unchanged |
| FMR LLC 0.00% of their portfolio | 4.7k $137.4k | Reduced -305 |
| Belvedere Trading LLC 0.07% of their portfolio | 4.0k $118.8k | Added +3.7k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 3.8k $112.8k | Reduced -1.2k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 3.2k $95.2k | Reduced -354 |
| VIRTUS ADVISERS, LLC 0.05% of their portfolio | 3.2k $93.8k | Reduced -1.1k |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 3.1k $92.5k | Unchanged |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 3.0k $109.3k | Unchanged |
| Byrne Asset Management LLC 0.06% of their portfolio | 2.7k $79.6k | Added +511 |
| Leonteq Securities AG 0.00% of their portfolio | 2.5k $73.8k | Unchanged |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.01% of their portfolio | 2.4k $72.2k | Added +1.1k |
| Metropolitan Life Insurance Co/NY 0.00% of their portfolio | 2.4k $70.1k | Unchanged |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 2.1k $63.4k | Unchanged |