CARIBOU BIOSCIENCES INC CRBU
COM · Common Stock · CUSIP 142038108 · ISIN US1420381089
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersBerkeley, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 88.3m as of 2023-08-03, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $4.24. Options: 6 managers hold calls ($111.1k notional), 5 hold puts ($106.0k).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 114 |
| Q4 2022 | 135 |
| Q1 2023 | 128 |
| Q2 2023 | 123 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 62 | 48 |
| Q1 2023 | 62 | 52 |
| Q2 2023 | 62 | 52 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $2.2m | $545.0k | 0.25 |
| Q4 2022 | $588.2k | $60.7k | 0.10 |
| Q1 2023 | $99.2k | $112.0k | 1.13 |
| Q2 2023 | $111.1k | $106.0k | 0.95 |
Biggest buyers
| PFM Health Sciences, LP | Added | +558.8k |
| Walleye Capital LLC | New | +494.1k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Added | +403.8k |
| MILLENNIUM MANAGEMENT LLC | Added | +397.6k |
| ALKEON CAPITAL MANAGEMENT LLC | Added | +302.4k |
| JANE STREET GROUP, LLC | New | +172.3k |
| RAYMOND JAMES & ASSOCIATES | Added | +156.2k |
| BANK OF AMERICA CORP /DE/ | Added | +119.1k |
| Bruce & Co., Inc. | Added | +100.0k |
| Trexquant Investment LP | New | +88.9k |
Biggest sellers
| STATE STREET CORP | Reduced | -2.3m |
| FMR LLC | Reduced | -1.4m |
| INTERNATIONAL BIOTECHNOLOGY TRUST PLC | Sold out | -457.9k |
| CITADEL ADVISORS LLC | Reduced | -280.7k |
| PICTET ASSET MANAGEMENT SA | Reduced | -256.9k |
| Rafferty Asset Management, LLC | Sold out | -233.8k |
| CITIGROUP INC | Reduced | -169.3k |
| Swiss National Bank | Sold out | -105.3k |
| WELLINGTON MANAGEMENT GROUP LLP | Sold out | -89.2k |
| Candriam S.C.A. | Sold out | -85.6k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $65.0k15.3k shares |
| CITADEL ADVISORS LLC | Added | $42.9k10.1k shares |
| GROUP ONE TRADING LLC | Added | $1.7k400 shares |
| SIMPLEX TRADING, LLC | Reduced | $1.0k300 shares |
| Belvedere Trading LLC | New | $425100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | Added | $88.0k20.7k shares |
| SIMPLEX TRADING, LLC | Added | $15.0k3.7k shares |
| GROUP ONE TRADING LLC | Added | $1.7k400 shares |
| Belvedere Trading LLC | New | $1.3k300 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +5.2 pts · filed 2026-07-27 | 7.2% |
Haurwitz Rachel E.
13D · may seek influence
new · filed 2025-04-25
Stated purposeThe Reporting Persons intend to continuously review their investment in the Issuer, and may in the future determine to (1) acquire additional securities of the Issuer, through open market purchases, private agreements, or otherwise (subject to the Issuer's Insider Trading Policy); (2) dispose of all or a portion of the securities of the Issuer owned by them (including through 10b5-1 plans) (subject to the Issuer's Insider Trading Policy); or (3) take any other available course of action. Notwithstanding anything contained herein, the Reporting Persons specifically reserve the right to change their intention with respect to any or all of such matters. Dr. Haurwitz is the President and Chief Executive Officer and serves as a member of the Board of Directors of the Issuer and acquired her se… Full filing |
5.0% |
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 3 | $269.8k | 0 | — | — |
| Q1 2022 | 1 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 1 | $485.2k | — |
| Q4 2022 | 0 | — | 1 | $108.0k | — |
| Q1 2023 | 0 | — | 1 | $35.5k | — |
| Q2 2023 | 0 | — | 0 | — | — |
None reported in Q2 2023.
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| PFM Health Sciences, LP 0.95% of their portfolio | 5.6m $23.7m | Added +558.8k |
| BlackRock Inc. 0.00% of their portfolio | 4.8m $20.2m | Added +10.0k |
| Avidity Partners Management LP 0.41% of their portfolio | 2.8m $11.7m | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 2.8m $11.7m | Added +119.1k |
| Rokos Capital Management LLP 0.22% of their portfolio | 2.7m $11.2m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.6m $10.9m | Reduced -45.8k |
| Elmwood Wealth Management, Inc. 4.68% of their portfolio | 2.4m $10.0m | Added +175 |
| PICTET ASSET MANAGEMENT SA 0.01% of their portfolio | 1.8m $7.7m | Reduced -256.9k |
| FMR LLC 0.00% of their portfolio | 1.4m $6.1m | Reduced -1.4m |
| ALKEON CAPITAL MANAGEMENT LLC 0.03% of their portfolio | 1.4m $5.8m | Added +302.4k |
| MORGAN STANLEY 0.00% of their portfolio | 1.3m $5.4m | Added +17.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.1m $4.7m | Added +41.9k |
| STATE STREET CORP 0.00% of their portfolio | 1.1m $4.5m | Reduced -2.3m |
| FIL Ltd 0.00% of their portfolio | 860.7k $3.7m | Unchanged |
| Assenagon Asset Management S.A. 0.01% of their portfolio | 762.1k $3.2m | Reduced -80.9k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 722.6k $3.1m | Added +397.6k |
| MAVERICK CAPITAL LTD 0.06% of their portfolio | 652.5k $2.8m | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 592.2k $2.5m | Reduced -10.8k |
| Tekla Capital Management LLC 0.09% of their portfolio | 567.1k $2.4m | Unchanged |
| Memorial Sloan Kettering Cancer Center 7.30% of their portfolio | 544.2k $2.3m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 532.0k $2.3m | Added +3.0k |
| Walleye Capital LLC 0.04% of their portfolio | 494.1k $2.1m | New |
| 72 Investment Holdings, LLC 15.70% of their portfolio | 474.1k $2.0m | Unchanged |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.01% of their portfolio | 436.0k $1.9m | Added +403.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 412.6k $1.8m | Added +2.2k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 289.7k $1.2m | Unchanged |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 270.6k $1.2m | Reduced -43.1k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio | 253.9k $1.1m | Reduced -33.1k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 251.7k $1.1m | Added +28.4k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 232.9k $989.7k | Reduced -60.1k |
| RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio | 210.6k $895.0k | Added +156.2k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 204.0k $867.0k | Added +18.0k |
| Bruce & Co., Inc. 0.24% of their portfolio | 200.0k $850.0k | Added +100.0k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 172.3k $732.3k | New |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 162.2k $689.4k | Added +83.1k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 130.7k $555.4k | Reduced -82.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 127.3k $541.1k | Reduced -1.6k |
| Granahan Investment Management, LLC 0.02% of their portfolio | 126.3k $536.8k | Added +4.6k |
| UBS Group AG 0.00% of their portfolio | 115.9k $492.5k | Reduced -23.9k |
| Green Alpha Advisors, LLC 0.30% of their portfolio | 105.8k $449.8k | Added +21.4k |
| Artal Group S.A. 0.01% of their portfolio | 105.3k $448.0k | Unchanged |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 100.9k $428.7k | Added +63.1k |
| Squarepoint Ops LLC 0.00% of their portfolio | 95.9k $407.6k | Added +24.3k |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA 0.05% of their portfolio | 90.7k $385.3k | Unchanged |
| Trexquant Investment LP 0.01% of their portfolio | 88.9k $377.7k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 86.5k $367.7k | Reduced -961 |
| Nelson Capital Management, LLC 0.09% of their portfolio | 85.0k $361.3k | Unchanged |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 83.6k $355.4k | New |
| HRT FINANCIAL LP 0.00% of their portfolio | 77.5k $329.0k | New |
| Curi Capital, LLC 0.01% of their portfolio | 74.6k $317.2k | Unchanged |
| STANSBERRY ASSET MANAGEMENT, LLC 0.06% of their portfolio | 71.5k $303.9k | Added +638 |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 68.4k $290.8k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 68.0k $288.8k | Added +28.4k |
| Invesco Ltd. 0.00% of their portfolio | 65.9k $280.3k | Reduced -3.5k |
| Long Focus Capital Management, LLC 0.04% of their portfolio | 65.0k $276.2k | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 49.6k $210.9k | New |
| Y-Intercept (Hong Kong) Ltd 0.02% of their portfolio | 44.2k $187.7k | New |
| Prime Capital Investment Advisors, LLC 0.00% of their portfolio | 40.3k $171.3k | Added +14.0k |
| ExodusPoint Capital Management, LP 0.00% of their portfolio | 39.4k $167.0k | New |
| CORNERCAP INVESTMENT COUNSEL INC 0.03% of their portfolio | 39.2k $166.7k | Unchanged |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 37.7k $160.0k | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 32.1k $170.2k | Unchanged |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 31.6k $134.0k | Added +7.2k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 31.0k $131.8k | Unchanged |
| EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio | 29.1k $123.5k | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 27.4k $116.6k | Added +11.7k |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 27.4k $116.4k | Added +309 |
| CITIGROUP INC 0.00% of their portfolio | 26.4k $112.0k | Reduced -169.3k |
| Penserra Capital Management LLC 0.00% of their portfolio | 25.2k $107.0k | Added +6.3k |
| NORGES BANK 0.00% of their portfolio | 24.8k $105.4k | Reduced -57.9k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 0.00% of their portfolio | 24.8k $105.2k | Reduced -18.6k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 24.7k $104.8k | Added +2.6k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 23.9k $101.6k | New |
| VIRTUS ADVISERS, LLC 0.06% of their portfolio | 23.5k $99.8k | Added +11.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 23.4k $99.3k | Reduced -27.2k |
| Walleye Trading LLC 0.01% of their portfolio | 23.2k $98.6k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 23.0k $97.8k | Reduced -11.8k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 22.6k $95.9k | Added +1.0k |
| SVB FINANCIAL GROUP 0.17% of their portfolio | 20.7k $88.0k | Reduced -6.9k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 19.0k $80.6k | Added +3.2k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 18.9k $80.4k | Reduced -44.8k |
| BARCLAYS PLC 0.00% of their portfolio | 18.2k $77.4k | Reduced -83.0k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 16.1k $68.6k | New |
| XTX Topco Ltd 0.01% of their portfolio | 15.6k $66.1k | Added +209 |
| LMR Partners LLP 0.00% of their portfolio | 15.2k $64.6k | Unchanged |
| Belvedere Trading LLC 0.02% of their portfolio | 15.1k $64.2k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 15.0k $63.8k | Reduced -67 |
| ROYCE & ASSOCIATES LP 0.00% of their portfolio | 14.7k $62.5k | Unchanged |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 14.7k $62.3k | Reduced -174 |
| Erste Asset Management GmbH 0.00% of their portfolio | 13.9k $56.7k | Unchanged |
| BSW Wealth Partners 0.01% of their portfolio | 13.6k $57.8k | Added +129 |
| PINNACLE ASSOCIATES LTD 0.00% of their portfolio | 12.9k $54.8k | Unchanged |
| Pinnacle Wealth Management Advisory Group, LLC 0.01% of their portfolio | 12.9k $54.8k | Unchanged |
| Ergoteles LLC 0.00% of their portfolio | 12.5k $53.1k | New |
| ProShare Advisors LLC 0.00% of their portfolio | 11.4k $48.3k | Added +538 |
| Centiva Capital, LP 0.00% of their portfolio | 10.7k $45.3k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 10.5k $45.0k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 8.1k $34.0k | Added +2.8k |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 8.1k $34.0k | Added +6.9k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 6.9k $29.2k | Added +3.2k |