CAREDX INC CDNA
COM · Common Stock · CUSIP 14167L103 · ISIN US14167L1035
Medical transplant company
- SectorHealth care
- IndustryServices-Medical Laboratories
- HeadquartersBrisbane, CA
- Founded2000
- Websitecaredx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($31.0m this quarter). Holder counts are more reliable. Shares outstanding: 51.4m as of 2025-10-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $18.84. Options: 4 managers hold calls ($1.7m notional), 2 hold puts ($3.8k).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 182 |
| Q4 2022 | 168 |
| Q1 2023 | 158 |
| Q2 2023 | 155 |
| Q3 2023 | 152 |
| Q4 2023 | 148 |
| Q1 2024 | 147 |
| Q2 2024 | 155 |
| Q3 2024 | 216 |
| Q4 2024 | 211 |
| Q1 2025 | 219 |
| Q2 2025 | 198 |
| Q3 2025 | 187 |
| Q4 2025 | 200 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 63 | 78 |
| Q2 2024 | 81 | 83 |
| Q3 2024 | 134 | 67 |
| Q4 2024 | 119 | 93 |
| Q1 2025 | 99 | 108 |
| Q2 2025 | 91 | 114 |
| Q3 2025 | 97 | 108 |
| Q4 2025 | 101 | 91 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $729.5k | $1.1m | 1.52 |
| Q2 2025 | $2.2m | $861.7k | 0.40 |
| Q3 2025 | $2.1m | $1.5m | 0.70 |
| Q4 2025 | $1.7m | $3.8k | 0.00 |
Biggest buyers
| Boston Partners | Added | +870.6k |
| D. E. Shaw & Co., Inc. | Added | +444.0k |
| Aberdeen Group plc | New | +345.3k |
| Chevy Chase Trust Holdings, LLC | Added | +337.6k |
| JANE STREET GROUP, LLC | Added | +337.2k |
| BNP PARIBAS FINANCIAL MARKETS | Added | +293.6k |
| Parkman Healthcare Partners LLC | New | +276.2k |
| JANUS HENDERSON GROUP PLC | Added | +265.7k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Added | +244.5k |
| ROYCE & ASSOCIATES LP | Added | +176.8k |
Biggest sellers
| Ophir Asset Management Pty Ltd | Reduced | -1.3m |
| FRED ALGER MANAGEMENT, LLC | Reduced | -754.3k |
| BRAIDWELL LP | Reduced | -597.6k |
| MACQUARIE GROUP LTD | Sold out | -463.0k |
| Connor, Clark & Lunn Investment Management Ltd. | Reduced | -404.7k |
| VANGUARD GROUP INC | Reduced | -321.5k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -314.0k |
| Sumitomo Mitsui Trust Group, Inc. | Reduced | -293.4k |
| Amova Asset Management Americas, Inc. | Reduced | -293.4k |
| Prosight Management, LP | Reduced | -254.0k |
Biggest calls
| JANE STREET GROUP, LLC | Reduced | $926.9k49.2k shares |
| CITADEL ADVISORS LLC | Reduced | $538.8k28.6k shares |
| GROUP ONE TRADING LLC | Added | $263.8k14.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $9.4k500 shares |
Biggest puts
| GROUP ONE TRADING LLC | Reduced | $1.9k100 shares |
| SIMPLEX TRADING, LLC | Reduced | $1.9k100 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +1.0 pts · filed 2026-07-27 | 9.0% |
Fell to 5% or below in the last year: BAMCO INC /NY/ (3.8%, 2026-08-14), STATE STREET CORP (4.8%, 2026-08-07), GAGNON SECURITIES LLC (4.4%, 2026-08-07), VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 2 | $4.3m | — |
| Q4 2024 | 0 | — | 2 | $324.7k | $324.7k |
| Q1 2025 | 0 | — | 2 | $449.0k | $81.8k |
| Q2 2025 | 0 | — | 6 | $2.3m | $663.3k |
| Q3 2025 | 0 | — | 2 | $220.2k | — |
| Q4 2025 | 0 | — | 1 | $181.6k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-12-04 | Novack Jeffrey Adam Secretary and General Counsel | Sold | $139.8k7.3k shares |
| 2025-11-07 | Novack Jeffrey Adam Secretary and General Counsel | Sold | $41.7k2.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 4.7m $87.6m | Reduced -116.5k |
| VANGUARD GROUP INC 0.00% of their portfolio | 3.4m $64.6m | Reduced -321.5k |
| BAMCO INC /NY/ 0.16% of their portfolio | 3.2m $59.4m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 2.7m $51.6m | Added +171.3k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.53% of their portfolio | 2.2m $41.3m | Unchanged |
| ARK Investment Management LLC 0.27% of their portfolio | 2.1m $40.2m | Reduced -34.2k |
| GAGNON SECURITIES LLC 6.81% of their portfolio | 1.8m $33.4m | Added +45.5k |
| BRAIDWELL LP 0.96% of their portfolio | 1.6m $29.9m | Reduced -597.6k |
| Sumitomo Mitsui Trust Group, Inc. 0.02% of their portfolio | 1.4m $27.3m | Reduced -293.4k |
| Amova Asset Management Americas, Inc. 0.31% of their portfolio | 1.4m $27.3m | Reduced -293.4k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 1.3m $24.7m | Added +93.5k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.2m $23.4m | Reduced -53.5k |
| RENAISSANCE TECHNOLOGIES LLC 0.03% of their portfolio | 1.1m $20.8m | Reduced -50.4k |
| Chevy Chase Trust Holdings, LLC 0.06% of their portfolio | 1.1m $20.4m | Added +337.6k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 1.0m $19.6m | Added +444.0k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.07% of their portfolio | 948.6k $17.9m | Added +244.5k |
| Ophir Asset Management Pty Ltd 1.96% of their portfolio | 925.4k $17.4m | Reduced -1.3m |
| Boston Partners 0.02% of their portfolio | 901.9k $17.0m | Added +870.6k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 811.2k $15.3m | Reduced -51.1k |
| Portolan Capital Management, LLC 0.77% of their portfolio | 758.8k $14.3m | Reduced -174.8k |
| ArrowMark Colorado Holdings LLC 0.31% of their portfolio | 758.4k $14.3m | Reduced -208.5k |
| Zweig-DiMenna Associates LLC 0.91% of their portfolio | 679.0k $12.8m | Added +104.0k |
| Connor, Clark & Lunn Investment Management Ltd. 0.03% of their portfolio | 665.1k $12.5m | Reduced -404.7k |
| CITADEL ADVISORS LLC 0.01% of their portfolio | 642.8k $12.1m | Added +18.9k |
| ROYCE & ASSOCIATES LP 0.11% of their portfolio | 581.2k $11.0m | Added +176.8k |
| First Eagle Investment Management, LLC 0.02% of their portfolio | 546.7k $10.3m | Added +71.6k |
| MORGAN STANLEY 0.00% of their portfolio | 541.5k $10.2m | Added +55.2k |
| Gagnon Advisors, LLC 6.37% of their portfolio | 532.9k $10.0m | Added +3.5k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 525.0k $9.9m | Reduced -282 |
| Blue Water Life Science Advisors, LP 6.03% of their portfolio | 510.0k $9.6m | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio | 487.1k $9.2m | Added +293.6k |
| Palo Alto Investors LP 1.25% of their portfolio | 478.2k $9.0m | Added +162.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 449.9k $8.5m | Reduced -42.9k |
| Bellevue Group AG 0.15% of their portfolio | 431.1k $8.1m | Reduced -141.9k |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 430.2k $8.1m | Added +337.2k |
| Russell Investments Group, Ltd. 0.01% of their portfolio | 420.2k $7.9m | Added +167.5k |
| PARAGON ASSOCIATES & PARAGON ASSOCIATES II JOINT VENTURE 14.60% of their portfolio | 375.0k $7.1m | Reduced -50.0k |
| SILVERCREST ASSET MANAGEMENT GROUP LLC 0.05% of their portfolio | 371.4k $7.0m | Unchanged |
| Aberdeen Group plc 0.01% of their portfolio | 345.3k $6.5m | New |
| Nuveen, LLC 0.00% of their portfolio | 333.9k $6.3m | Added +165.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 324.8k $6.1m | Added +6.2k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 303.0k $5.7m | Added +115.1k |
| JANUS HENDERSON GROUP PLC 0.00% of their portfolio | 287.6k $5.4m | Added +265.7k |
| Parkman Healthcare Partners LLC 0.50% of their portfolio | 276.2k $5.2m | New |
| Prosight Management, LP 0.97% of their portfolio | 250.0k $4.7m | Reduced -254.0k |
| Bullseye Asset Management LLC 2.39% of their portfolio | 235.5k $4.4m | Added +10.0k |
| Man Group plc 0.01% of their portfolio | 233.2k $4.4m | Added +79.0k |
| Legal & General Group Plc 0.00% of their portfolio | 230.5k $4.3m | Added +70.5k |
| FMR LLC 0.00% of their portfolio | 209.4k $3.9m | Added +53.8k |
| FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio | 174.7k $3.3m | Reduced -754.3k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 169.9k $3.2m | Added +15.1k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 169.9k $3.2m | Reduced -14.7k |
| BARCLAYS PLC 0.00% of their portfolio | 164.4k $3.1m | Reduced -22.5k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 162.0k $3.1m | Reduced -4.8k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 139.4k $2.6m | Added +120.7k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 125.2k $2.4m | Reduced -15.7k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.01% of their portfolio | 125.0k $2.4m | Reduced -43.7k |
| Engineers Gate Manager LP 0.03% of their portfolio | 120.4k $2.3m | Added +21.5k |
| UBS Group AG 0.00% of their portfolio | 120.0k $2.3m | Added +8.6k |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 116.3k $2.2m | Reduced -10.0k |
| Invesco Ltd. 0.00% of their portfolio | 115.5k $2.2m | Added +5.8k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 103.7k $2.0m | Added +3.8k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 102.3k $1.9m | Added +74.2k |
| Jump Financial, LLC 0.02% of their portfolio | 101.0k $1.9m | Added +67.8k |
| FORMULA GROWTH LTD 0.73% of their portfolio | 100.7k $1.9m | Reduced -91.6k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 99.9k $1.9m | Added +59.7k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 99.7k $1.9m | Reduced -314.0k |
| Swiss National Bank 0.00% of their portfolio | 99.7k $1.9m | Reduced -2.8k |
| ARS Investment Partners, LLC 0.10% of their portfolio | 94.3k $1.8m | Reduced -11.7k |
| Rafferty Asset Management, LLC 0.01% of their portfolio | 91.1k $1.7m | Reduced -1.4k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 89.3k $1.7m | New |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 87.6k $1.7m | Added +16.0k |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd 0.11% of their portfolio | 83.5k $1.6m | Added +25.2k |
| Gotham Asset Management, LLC 0.01% of their portfolio | 82.6k $1.6m | New |
| GLOBEFLEX CAPITAL L P 0.23% of their portfolio | 79.8k $1.5m | Added +8.8k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 78.8k $1.5m | New |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 78.6k $1.5m | Added +24.5k |
| ALGERT GLOBAL LLC 0.02% of their portfolio | 70.2k $1.3m | Added +27.8k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 69.2k $1.3m | Reduced -12.7k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 61.5k $1.2m | Reduced -3.1k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 57.1k $1.1m | Added +23.5k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 55.5k $1.0m | Added +11.4k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 52.5k $990.0k | Added +104 |
| OP Asset Management Ltd 0.01% of their portfolio | 52.4k $986.9k | Added +27.1k |
| Aquatic Capital Management LLC 0.03% of their portfolio | 52.1k $981.1k | Reduced -37.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 47.5k $895.7k | Reduced -30.6k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 46.5k $875.3k | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 46.4k $874.0k | Reduced -482 |
| Palumbo Wealth Management LLC 0.21% of their portfolio | 45.8k $862.1k | Added +8.8k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 45.1k $850.5k | Reduced -82.4k |
| EXCHANGE TRADED CONCEPTS, LLC 0.01% of their portfolio | 43.6k $821.2k | Reduced -7.9k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 40.6k $760.0k | New |
| VIRTUS ADVISERS, LLC 0.36% of their portfolio | 40.6k $764.2k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 39.5k $744.3k | Reduced -89.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 39.2k $739.0k | Added +711 |
| CANADA PENSION PLAN INVESTMENT BOARD 0.00% of their portfolio | 38.6k $727.2k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 38.1k $718.2k | Reduced -6.4k |
| PROFUND ADVISORS LLC 0.02% of their portfolio | 33.9k $638.1k | Added +13.8k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 33.2k $628.7k | New |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 31.2k $588.6k | New |