CARDIFF ONCOLOGY INC CRDF
COM · Common Stock · CUSIP 14147L108
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersSan Diego, CA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($9.3k this quarter). Holder counts are more reliable. Shares outstanding: 77.8m as of 2026-08-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.29. Options: 4 managers hold calls ($956.4k notional), 4 hold puts ($32.1k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 59 |
| Q4 2022 | 62 |
| Q1 2023 | 56 |
| Q2 2023 | 54 |
| Q3 2023 | 57 |
| Q4 2023 | 56 |
| Q1 2024 | 78 |
| Q2 2024 | 91 |
| Q3 2024 | 84 |
| Q4 2024 | 118 |
| Q1 2025 | 117 |
| Q2 2025 | 116 |
| Q3 2025 | 112 |
| Q4 2025 | 110 |
| Q1 2026 | 117 |
| Q2 2026 | 104 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 32 | 38 |
| Q4 2024 | 65 | 20 |
| Q1 2025 | 64 | 32 |
| Q2 2025 | 64 | 41 |
| Q3 2025 | 52 | 47 |
| Q4 2025 | 42 | 52 |
| Q1 2026 | 49 | 51 |
| Q2 2026 | 55 | 56 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $2.6m | $902.1k | 0.34 |
| Q4 2025 | $2.1m | $284.1k | 0.14 |
| Q1 2026 | $1.2m | $118.1k | 0.10 |
| Q2 2026 | $956.4k | $32.1k | 0.03 |
Biggest buyers
| JANE STREET GROUP, LLC | Added | +567.8k |
| Laurion Capital Management LP | Added | +451.6k |
| AQR CAPITAL MANAGEMENT LLC | Added | +280.2k |
| HRT FINANCIAL LP | New | +272.8k |
| UBS Group AG | Added | +238.1k |
| BNP PARIBAS FINANCIAL MARKETS | Added | +215.4k |
| X-Square Capital, LLC | New | +205.7k |
| MORGAN STANLEY | Added | +189.8k |
| MARSHALL WACE, LLP | New | +162.2k |
| Qube Research & Technologies Ltd | New | +125.5k |
Biggest sellers
| BlackRock, Inc. | Reduced | -3.0m |
| ACORN CAPITAL ADVISORS, LLC | Sold out | -1.8m |
| STATE STREET CORP | Reduced | -855.6k |
| GEODE CAPITAL MANAGEMENT, LLC | Reduced | -779.6k |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Reduced | -365.2k |
| FLPUTNAM INVESTMENT MANAGEMENT CO | Reduced | -347.7k |
| NORTHERN TRUST CORP | Reduced | -340.3k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | Sold out | -164.7k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -159.3k |
| XTX Topco Ltd | Reduced | -152.8k |
Biggest calls
| GROUP ONE TRADING LLC | Added | $528.7k406.7k shares |
| CITADEL ADVISORS LLC | Reduced | $239.7k184.4k shares |
| JANE STREET GROUP, LLC | New | $105.3k81.0k shares |
| SIMPLEX TRADING, LLC | Added | $82.7k63.6k shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $16.9k13.0k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $14.7k11.3k shares |
| GROUP ONE TRADING LLC | Unchanged | $260200 shares |
| SIMPLEX TRADING, LLC | Reduced | $260200 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
No one currently above 5% in the filings since 19 Dec 2024.
Fell to 5% or below in the last year: BlackRock, Inc. (1.3%, 2026-07-27), VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 3 | $1.0m | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 1 | $710.5k | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 2 | $66.5k | 0 | — | — |
| Q3 2026 | 2 | $1.1m | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-07-14 | PACE GARY W Director | Bought | $1.0m687.3k shares |
| 2026-07-14 | Mohindru Mani Chief Executive Officer, director | Bought | $50.2k34.4k shares |
| 2026-06-18 | PACE GARY W Director | Bought | $36.6k30.0k shares |
| 2026-06-18 | Mohindru Mani Chief Executive Officer, director | Bought | $29.9k24.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Laurion Capital Management LP 0.29% of their portfolio | 3.1m $4.0m | Added +451.6k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.9m $3.8m | Added +39.6k |
| Pfizer Inc 1.77% of their portfolio | 2.4m $3.0m | Unchanged |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 1.2m $1.6m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 972.9k $1.3m | Reduced -3.0m |
| BLAIR WILLIAM & CO/IL 0.00% of their portfolio | 912.5k $1.2m | Reduced -9.9k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 820.1k $1.1m | Reduced -779.6k |
| UBS Group AG 0.00% of their portfolio | 638.7k $830.3k | Added +238.1k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 607.9k $790.3k | Added +567.8k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 410.6k $533.8k | Reduced -35.6k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 346.4k $450.3k | Added +280.2k |
| STATE STREET CORP 0.00% of their portfolio | 331.4k $430.8k | Reduced -855.6k |
| HRT FINANCIAL LP 0.00% of their portfolio | 272.8k $354.0k | New |
| FLPUTNAM INVESTMENT MANAGEMENT CO 0.00% of their portfolio | 247.5k $321.7k | Reduced -347.7k |
| MORGAN STANLEY 0.00% of their portfolio | 246.1k $319.9k | Added +189.8k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 228.5k $297.0k | Added +215.4k |
| X-Square Capital, LLC 0.07% of their portfolio | 205.7k $267.0k | New |
| GSA CAPITAL PARTNERS LLP 0.01% of their portfolio | 173.3k $225.0k | Added +50.3k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 162.2k $210.9k | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 161.7k $210.2k | Reduced -141.7k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 152.9k $198.7k | Reduced -340.3k |
| Avestar Capital, LLC 0.01% of their portfolio | 136.1k $177.0k | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 134.5k $174.9k | Added +111.5k |
| Assenagon Asset Management S.A. 0.00% of their portfolio | 134.5k $174.8k | Added +67.2k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 125.5k $163.2k | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 120.8k $157.1k | Reduced -14.8k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 116.1k $151.0k | Added +23.8k |
| AlphaCore Capital LLC 0.00% of their portfolio | 108.5k $141.0k | Added +67 |
| XTX Topco Ltd 0.00% of their portfolio | 97.4k $126.6k | Reduced -152.8k |
| Squarepoint Ops LLC 0.00% of their portfolio | 96.1k $124.9k | Added +69.7k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 72.1k $93.7k | Reduced -365.2k |
| Virtu Financial LLC 0.00% of their portfolio | 71.3k $93.0k | Added +57.7k |
| CAPSTONE INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 51.2k $66.5k | Unchanged |
| Mariner, LLC 0.00% of their portfolio | 49.4k $64.2k | Added +34.9k |
| Creative Planning 0.00% of their portfolio | 48.1k $62.5k | Added +4.5k |
| ELKHORN PARTNERS LIMITED PARTNERSHIP 0.05% of their portfolio | 48.0k $62.4k | Added +3.5k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 47.7k $62.0k | Reduced -159.3k |
| IEQ CAPITAL, LLC 0.00% of their portfolio | 44.6k $58.0k | New |
| Glenview Trust Co 0.00% of their portfolio | 43.1k $56.1k | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 36.6k $47.6k | Unchanged |
| HighTower Advisors, LLC 0.00% of their portfolio | 34.8k $45.2k | Added +598 |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 30.1k $39.1k | Reduced -43.8k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 29.0k $36.8k | New |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 28.4k $36.9k | New |
| Quadrature Capital Ltd 0.00% of their portfolio | 26.9k $34.9k | New |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 25.3k $32.9k | Unchanged |
| Engineers Gate Manager LP 0.00% of their portfolio | 25.0k $32.5k | New |
| Tamar Securities, LLC 0.00% of their portfolio | 23.8k $30.9k | Added +4.5k |
| MAI Capital Management 0.00% of their portfolio | 23.4k $30.4k | Reduced -6.1k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 22.7k $29.5k | Unchanged |
| Post Resch Tallon Group Inc. 0.02% of their portfolio | 22.5k $29.3k | Unchanged |
| Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio | 22.4k $29.1k | New |
| R Squared Ltd 0.02% of their portfolio | 22.0k $28.6k | Added +10.2k |
| PFG Investments, LLC 0.00% of their portfolio | 20.5k $26.7k | Added +8.0k |
| BRIGHTON JONES LLC 0.00% of their portfolio | 20.5k $26.6k | Added +3.5k |
| Baker Ellis Asset Management LLC 0.00% of their portfolio | 20.0k $26.0k | Unchanged |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 20.0k $26.0k | Reduced -36.5k |
| Proactive Wealth Strategies LLC 0.00% of their portfolio | 20.0k $26.0k | Unchanged |
| Capital Advisors Wealth Management, LLC 0.00% of their portfolio | 15.5k $20.2k | Added +525 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 15.1k $19.7k | Reduced -23.3k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 14.0k $18.2k | Added +1.7k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 13.9k $18.1k | Reduced -87.3k |
| AXQ CAPITAL, LP 0.00% of their portfolio | 13.1k $17.0k | New |
| Gladstone Institutional Advisory LLC 0.00% of their portfolio | 13.0k $16.9k | Unchanged |
| INTEGRITY ALLIANCE, LLC. 0.00% of their portfolio | 12.9k $16.7k | Unchanged |
| MERCER GLOBAL ADVISORS INC /ADV 0.00% of their portfolio | 12.8k $16.6k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 12.3k $16.0k | Added +7.1k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 12.2k $15.8k | Reduced -38.9k |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio | 12.1k $16.1k | New |
| Ledgewood Wealth Advisors, LLC 0.01% of their portfolio | 11.2k $14.5k | Unchanged |
| Scarborough Advisors, LLC 0.00% of their portfolio | 10.5k $16.2k | Unchanged |
| Optiver Holding B.V. 0.00% of their portfolio | 10.2k $13.2k | Added +8.5k |
| Focus Partners Wealth 0.00% of their portfolio | 10.1k $13.2k | New |
| FMR LLC 0.00% of their portfolio | 9.8k $12.7k | Reduced -31.1k |
| Security National Bank 0.00% of their portfolio | 9.8k $12.7k | Unchanged |
| TRUST CO OF TOLEDO NA /OH/ 0.00% of their portfolio | 9.0k $11.7k | Unchanged |
| Arax Advisory Partners 0.00% of their portfolio | 7.7k $10.0k | Added +7.3k |
| Golden State Wealth Management, LLC 0.00% of their portfolio | 7.0k $9.2k | New |
| BARCLAYS PLC 0.00% of their portfolio | 5.4k $7.0k | Reduced -6.3k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 4.8k $6.3k | Added +2.6k |
| IFP Advisors, Inc 0.00% of their portfolio | 3.8k $5.0k | Added +3.8k |
| US BANCORP \DE\ 0.00% of their portfolio | 3.1k $4.0k | Unchanged |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 3.1k $4.0k | Reduced -13.4k |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 2.9k $3.7k | Added +2.9k |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 2.2k $2.9k | Added +1.5k |
| Essential Partners LLC 0.00% of their portfolio | 2.1k $2.7k | Reduced -482 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.9k $2.4k | Reduced -24.8k |
| Integrated Wealth Concepts LLC 0.00% of their portfolio | 1.4k $1.9k | New |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 1.1k $1.4k | Added +760 |
| Allworth Financial LP 0.00% of their portfolio | 712 $926 | Added +692 |
| Clearstead Advisors, LLC 0.00% of their portfolio | 700 $910 | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 501 $651 | Reduced -39.8k |
| Fortitude Family Office, LLC 0.00% of their portfolio | 379 $493 | New |
| GAMMA Investing LLC 0.00% of their portfolio | 147 $191 | Reduced -1.1k |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 145 $189 | Added +1 |
| ROTHSCHILD INVESTMENT LLC 0.00% of their portfolio | 90 $117 | Added +79 |
| NewEdge Advisors, LLC 0.00% of their portfolio | 81 $105 | Unchanged |
| SJS Investment Consulting Inc. 0.00% of their portfolio | 63 $82 | New |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 50 $63 | Unchanged |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 0.00% of their portfolio | 48 $62 | Unchanged |