TVARDI THERAPEUTICS INC TVRD
COM · Common Stock · CUSIP 140755307 · ISIN US1407553072
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersSugar Land, TX
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 9.4m as of 2025-08-08, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $23.08. Options: 1 managers hold calls ($0 notional), 1 hold puts ($0).
Trends to Q2 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 1 |
| Q4 2022 | 1 |
| Q1 2023 | 1 |
| Q2 2023 | 1 |
| Q3 2023 | 1 |
| Q4 2023 | 0 |
| Q1 2024 | 0 |
| Q2 2024 | 0 |
| Q3 2024 | 0 |
| Q4 2024 | 0 |
| Q1 2025 | 0 |
| Q2 2025 | 49 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 0 | 0 |
| Q1 2023 | 0 | 0 |
| Q2 2023 | 0 | 0 |
| Q3 2023 | 0 | 0 |
| Q4 2023 | 0 | 1 |
Biggest buyers
| Slate Path Capital LP | New | +704.1k |
| VANGUARD GROUP INC | New | +398.4k |
| BlackRock, Inc. | New | +267.9k |
| 683 Capital Management, LLC | New | +176.0k |
| GEODE CAPITAL MANAGEMENT, LLC | New | +112.1k |
| STATE STREET CORP | New | +41.5k |
| RENAISSANCE TECHNOLOGIES LLC | New | +31.2k |
| NORTHERN TRUST CORP | New | +30.4k |
| UBS Group AG | New | +29.4k |
| MARSHALL WACE, LLP | New | +25.0k |
Biggest sellers
| None |
Biggest calls
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | New | $00 shares |
Biggest puts
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | New | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Slate Path Capital LP 13G · institution new · filed 2025-08-14 | 7.5% |
Fell to 5% or below in the last year: DePinho Ronald A (4.5%, 2026-02-17)
Insider purchases and sales in Q2 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2023 | 0 | — | 1 | $13.2k | $13.2k |
| Q4 2023 | 0 | — | 1 | $4.6k | — |
| Q1 2024 | 0 | — | 3 | $8.1k | — |
| Q2 2024 | 0 | — | 3 | $5.2k | — |
| Q3 2024 | 0 | — | 1 | $1.5k | — |
| Q4 2024 | 0 | — | 1 | — | — |
| Q1 2025 | 0 | — | 2 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
None reported in Q2 2025.
Holders, Q2 2025
| Manager | Shares | Change |
|---|---|---|
| Slate Path Capital LP 0.28% of their portfolio | 704.1k $16.4m | New |
| VANGUARD GROUP INC 0.00% of their portfolio | 398.4k $9.3m | New |
| BlackRock, Inc. 0.00% of their portfolio | 267.9k $6.2m | New |
| 683 Capital Management, LLC 0.37% of their portfolio | 176.0k $3.6m | New |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 112.1k $2.6m | New |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.00% of their portfolio | 43.2k $1.0m | Not comparable |
| STATE STREET CORP 0.00% of their portfolio | 41.5k $968.9k | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 31.2k $728.7k | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 30.4k $709.4k | New |
| UBS Group AG 0.00% of their portfolio | 29.4k $684.8k | New |
| MARSHALL WACE, LLP 0.00% of their portfolio | 25.0k $582.8k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 17.1k $398.6k | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 12.1k $281.2k | New |
| BARCLAYS PLC 0.00% of their portfolio | 5.8k $135.1k | New |
| MORGAN STANLEY 0.00% of their portfolio | 4.9k $114.2k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 4.0k $92.0k | New |
| Headlands Technologies LLC 0.01% of their portfolio | 3.4k $80.0k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 3.4k $79.6k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 3.0k $70.7k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 2.5k $58.5k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 1.9k $43.5k | New |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 1.7k $38.9k | New |
| CITIGROUP INC 0.00% of their portfolio | 1.2k $26.9k | New |
| Arax Advisory Partners 0.00% of their portfolio | 867 $20.2k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 532 $12.0k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 349 $8.1k | New |
| Legal & General Group Plc 0.00% of their portfolio | 310 $7.2k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 300 $7.0k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 213 $5.0k | New |
| AMALGAMATED BANK 0.00% of their portfolio | 117 $3.0k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 103 $2.4k | New |
| Sterling Capital Management LLC 0.00% of their portfolio | 82 $1.9k | New |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 65 $1.5k | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 41 $954 | New |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 24 $591 | New |
| McIlrath & Eck, LLC 0.00% of their portfolio | 20 $467 | New |
| Allworth Financial LP 0.00% of their portfolio | 19 $444 | New |
| HARBOUR INVESTMENTS, INC. 0.00% of their portfolio | 14 $327 | New |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 14 $327 | New |
| Kiker Wealth Management, LLC 0.00% of their portfolio | 13 $303 | New |
| Leonteq Securities AG 0.00% of their portfolio | 12 $280 | New |
| MAI Capital Management 0.00% of their portfolio | 10 $234 | New |
| TRUST CO OF TOLEDO NA /OH/ 0.00% of their portfolio | 9 $210 | New |
| FMR LLC 0.00% of their portfolio | 5 $117 | New |
| Truvestments Capital LLC 0.00% of their portfolio | 4 $93 | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 4 $93 | New |
| Sound Income Strategies, LLC 0.00% of their portfolio | 2 $47 | New |
| COMERICA BANK 0.00% of their portfolio | 1 $23 | New |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 1 $23 | New |