CABALETTA BIO INC CABA
COM · Common Stock · CUSIP 12674W109
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersPhiladelphia, PA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.4m this quarter). Holder counts are more reliable. Shares outstanding: 39.8m as of 2023-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $12.91. Options: 5 managers hold calls ($1.4m notional), 5 hold puts ($529.1k).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 54 |
| Q4 2022 | 62 |
| Q1 2023 | 73 |
| Q2 2023 | 85 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 31 | 35 |
| Q1 2023 | 44 | 26 |
| Q2 2023 | 57 | 29 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $135.0k | $12.0k | 0.09 |
| Q4 2022 | $981.4k | $184.8k | 0.19 |
| Q1 2023 | $800.3k | $120.2k | 0.15 |
| Q2 2023 | $1.4m | $529.1k | 0.37 |
Biggest buyers
| Bain Capital Life Sciences Investors, LLC | New | +2.0m |
| DEERFIELD MANAGEMENT COMPANY, L.P. | Added | +1.9m |
| BlackRock Inc. | Added | +1.5m |
| Redmile Group, LLC | Added | +1.1m |
| Invesco Ltd. | New | +856.9k |
| PERCEPTIVE ADVISORS LLC | Added | +820.2k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Added | +725.0k |
| VANGUARD GROUP INC | Added | +607.6k |
| FRED ALGER MANAGEMENT, LLC | Added | +557.6k |
| Commodore Capital LP | Added | +533.2k |
Biggest sellers
| Lynx1 Capital Management LP | Reduced | -273.2k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Sold out | -265.4k |
| MARSHALL WACE, LLP | Reduced | -243.6k |
| MILLENNIUM MANAGEMENT LLC | Reduced | -201.0k |
| GOLDMAN SACHS GROUP INC | Sold out | -161.6k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | Reduced | -125.3k |
| JANE STREET GROUP, LLC | Sold out | -103.8k |
| HRT FINANCIAL LP | Sold out | -100.2k |
| BARCLAYS PLC | Reduced | -62.1k |
| Squarepoint Ops LLC | Reduced | -46.6k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $1.1m85.1k shares |
| CITADEL ADVISORS LLC | Reduced | $158.8k12.3k shares |
| SIMPLEX TRADING, LLC | Reduced | $98.0k7.6k shares |
| GROUP ONE TRADING LLC | Reduced | $77.5k6.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $365.4k28.3k shares |
| CITADEL ADVISORS LLC | Reduced | $99.4k7.7k shares |
| SIMPLEX TRADING, LLC | Added | $63.0k4.9k shares |
| GROUP ONE TRADING LLC | New | $1.3k100 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| T. Rowe Price Investment Management, Inc. 13G · institution +1.4 pts · filed 2026-08-14 | 11.6% |
| PRUDENTIAL FINANCIAL INC 13G · institution +2.5 pts · filed 2026-06-05 | 11.4% |
| JENNISON ASSOCIATES LLC 13G · institution +2.5 pts · filed 2026-06-04 | 11.4% |
| Bain Capital Life Sciences Opportunities III, LP 13G · passive investor no change · filed 2026-08-14 | 10.0% |
| Adage Capital Management, L.P. 13G · institution -1.6 pts · filed 2026-08-12 | 8.4% |
| BlackRock, Inc. 13G · institution +1.8 pts · filed 2026-10-27 | 7.7% |
| Cormorant Asset Management, LP 13G · institution -3.1 pts · filed 2026-08-14 | 6.0% |
| NORGES BANK 13G · institution new · filed 2026-08-12 | 5.4% |
| VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-07-31 | 5.1% |
Fell to 5% or below in the last year: MILLENNIUM MANAGEMENT LLC (1.3%, 2026-07-23), Alyeska Investment Group, L.P. (4.7%, 2026-02-17), CITADEL ADVISORS LLC (3.4%, 2025-11-14)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 0 | — | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 5 | $343.4k | 0 | — | — |
| Q1 2023 | 0 | — | 0 | — | — |
| Q2 2023 | 0 | — | 1 | $402.7k | $402.7k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-06-20 | Binder Gwendolyn Officer | Sold plan | $142.9k11.0k shares |
| 2023-05-19 | Binder Gwendolyn Officer | Sold plan | $259.8k22.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| FRED ALGER MANAGEMENT, LLC 0.30% of their portfolio | 4.6m $59.0m | Added +557.6k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.09% of their portfolio | 3.3m $42.2m | Added +725.0k |
| Commodore Capital LP 3.44% of their portfolio | 2.4m $30.6m | Added +533.2k |
| DEERFIELD MANAGEMENT COMPANY, L.P. 0.64% of their portfolio | 2.3m $30.2m | Added +1.9m |
| Cormorant Asset Management, LP 1.63% of their portfolio | 2.2m $28.7m | Added +400.0k |
| Lynx1 Capital Management LP 18.45% of their portfolio | 2.2m $28.2m | Reduced -273.2k |
| Bain Capital Life Sciences Investors, LLC 2.66% of their portfolio | 2.0m $25.8m | New |
| Venrock Adviser, LLC 4.07% of their portfolio | 2.0m $25.5m | Unchanged |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.7m $22.2m | Added +607.6k |
| BlackRock Inc. 0.00% of their portfolio | 1.7m $22.1m | Added +1.5m |
| BAKER BROS. ADVISORS LP 0.12% of their portfolio | 1.6m $20.6m | Added +250.0k |
| PERCEPTIVE ADVISORS LLC 0.58% of their portfolio | 1.5m $19.9m | Added +820.2k |
| Redmile Group, LLC 0.68% of their portfolio | 1.4m $17.7m | Added +1.1m |
| JENNISON ASSOCIATES LLC 0.01% of their portfolio | 1.2m $15.2m | Added +400.0k |
| Invesco Ltd. 0.00% of their portfolio | 856.9k $11.1m | New |
| Boxer Capital, LLC 0.32% of their portfolio | 540.0k $7.0m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 502.7k $6.5m | Added +282.9k |
| Blackstone Inc. 0.03% of their portfolio | 498.8k $6.4m | Reduced -15.7k |
| TCG Crossover Management, LLC 1.03% of their portfolio | 486.8k $6.3m | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 461.5k $6.0m | Added +379.0k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 371.1k $4.8m | Reduced -201.0k |
| Velan Capital Investment Management LP 3.03% of their portfolio | 250.0k $3.2m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 214.5k $2.8m | Added +174.3k |
| MORGAN STANLEY 0.00% of their portfolio | 207.4k $2.7m | Added +5.0k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 186.8k $2.4m | New |
| Rokos Capital Management LLP 0.05% of their portfolio | 173.8k $2.3m | New |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 134.8k $1.7m | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 125.3k $1.6m | Added +99.6k |
| Affinity Asset Advisors, LLC 0.64% of their portfolio | 125.0k $1.6m | New |
| FIRST MANHATTAN CO. LLC. 0.01% of their portfolio | 117.6k $1.5m | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 115.8k $1.5m | Added +14.7k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 85.7k $1.1m | Reduced -243.6k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 82.1k $1.1m | New |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.02% of their portfolio | 81.3k $1.0m | Added +36.3k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 77.7k $1.0m | Reduced -35.1k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 68.5k $885.0k | Added +58.5k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 59.7k $770.3k | New |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 50.6k $653.5k | Reduced -125.3k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 46.0k $593.7k | Reduced -38.7k |
| Nan Fung Group Holdings Ltd 0.34% of their portfolio | 41.1k $530.9k | New |
| GSA CAPITAL PARTNERS LLP 0.05% of their portfolio | 38.9k $502.0k | New |
| Veritable, L.P. 0.01% of their portfolio | 37.2k $480.8k | Unchanged |
| LPL Financial LLC 0.00% of their portfolio | 31.6k $408.0k | Added +6.8k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 29.0k $374.1k | New |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 25.5k $329.2k | Added +16.6k |
| ENVESTNET ASSET MANAGEMENT INC 0.00% of their portfolio | 25.5k $328.7k | Added +4.6k |
| J.P. Morgan Private Wealth Advisors LLC 0.00% of their portfolio | 23.5k $302.8k | Reduced -9.6k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 20.5k $264.2k | Added +19.8k |
| UBS Group AG 0.00% of their portfolio | 14.9k $192.6k | Added +13.3k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 13.9k $179.1k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 13.7k $177.3k | Added +11.7k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 13.6k $175.2k | New |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 13.0k $167.8k | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 12.6k $163.0k | New |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 12.3k $158.9k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 11.4k $147.7k | New |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 11.1k $143.3k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 10.5k $135.4k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 10.4k $134.5k | Reduced -46.6k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 10.2k $131.8k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 10.0k $129.1k | New |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 8.5k $109.8k | New |
| CITIGROUP INC 0.00% of their portfolio | 7.6k $98.3k | Reduced -38.1k |
| BARCLAYS PLC 0.00% of their portfolio | 5.1k $65.8k | Reduced -62.1k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 4.2k $54.8k | Reduced -2.4k |
| AMALGAMATED BANK 0.00% of their portfolio | 3.7k $48.0k | New |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 3.1k $39.0k | Added +100 |
| Legal & General Group Plc 0.00% of their portfolio | 3.0k $39.1k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 2.1k $27.3k | New |
| Metropolitan Life Insurance Co/NY 0.00% of their portfolio | 1.4k $18.2k | New |
| WR Wealth Planners, LLC 0.00% of their portfolio | 900 $11.6k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 817 $10.5k | Reduced -4.2k |
| Endurance Wealth Management, Inc. 0.00% of their portfolio | 800 $11.0k | Unchanged |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 714 $9.2k | Added +138 |
| PRIVATE TRUST CO NA 0.00% of their portfolio | 497 $6.4k | Added +129 |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 340 $4.4k | Unchanged |
| FOSTER DYKEMA CABOT & CO INC/MA 0.00% of their portfolio | 309 $4.0k | New |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 273 $3.5k | New |
| Impact Partnership Wealth, LLC 0.00% of their portfolio | 273 $3.5k | First filing |
| FMR LLC 0.00% of their portfolio | 237 $3.1k | Added +209 |
| Capital Advisors, Ltd. LLC 0.00% of their portfolio | 81 $1.0k | Unchanged |
| Beaird Harris Wealth Management, LLC 0.00% of their portfolio | 79 $1.0k | Unchanged |
| Bogart Wealth, LLC 0.00% of their portfolio | 50 $646 | Unchanged |
| NewSquare Capital LLC 0.00% of their portfolio | 10 $129 | Unchanged |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |