BICYCLE THERAPEUTICS PLC BCYC
SPONSORED ADS · ADR · CUSIP 088786108 · ISIN US0887861088
Company in Cambridge, United Kingdom
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersCambridge, United Kingdom
- Founded2009
- Websitebicycletherapeutics.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($630.3k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $25.52. Options: 5 managers hold calls ($170.8k notional), 6 hold puts ($5.3m).
Trends to Q2 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 80 |
| Q4 2022 | 87 |
| Q1 2023 | 90 |
| Q2 2023 | 86 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 32 | 43 |
| Q1 2023 | 53 | 29 |
| Q2 2023 | 39 | 41 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $18.0k | $18.0k | 1.00 |
| Q4 2022 | $538.2k | $3.3m | 6.12 |
| Q1 2023 | $9.7m | $2.5m | 0.26 |
| Q2 2023 | $170.8k | $5.3m | 30.96 |
Biggest buyers
| First Light Asset Management, LLC | Added | +1.0m |
| NOMURA HOLDINGS INC | New | +400.0k |
| Paradigm Biocapital Advisors LP | Added | +168.6k |
| ARMISTICE CAPITAL, LLC | Added | +140.0k |
| KENNEDY CAPITAL MANAGEMENT LLC | New | +123.2k |
| Verition Fund Management LLC | Added | +96.5k |
| AXA S.A. | Added | +93.5k |
| Legal & General Group Plc | Added | +67.1k |
| MILLENNIUM MANAGEMENT LLC | Added | +61.9k |
| CITADEL ADVISORS LLC | Added | +44.0k |
Biggest sellers
| Point72 Asset Management, L.P. | Reduced | -324.4k |
| FMR LLC | Reduced | -287.1k |
| Polar Capital Holdings Plc | Reduced | -250.0k |
| Logos Global Management LP | Reduced | -230.0k |
| JANUS HENDERSON GROUP PLC | Reduced | -193.1k |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD | Reduced | -127.0k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -108.0k |
| MORGAN STANLEY | Reduced | -68.2k |
| MARSHALL WACE, LLP | Reduced | -67.4k |
| J. Goldman & Co LP | Sold out | -49.9k |
Biggest calls
| CITADEL ADVISORS LLC | Reduced | $74.0k2.9k shares |
| GROUP ONE TRADING LLC | New | $63.8k2.5k shares |
| SIMPLEX TRADING, LLC | Reduced | $33.0k1.3k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
| Cutler Group LLC / CA | Added | $0800 shares |
Biggest puts
| GROUP ONE TRADING LLC | Added | $2.2m87.7k shares |
| SIMPLEX TRADING, LLC | Added | $1.5m60.6k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $783.5k30.7k shares |
| CITADEL ADVISORS LLC | Added | $709.5k27.8k shares |
| Cutler Group LLC / CA | Added | $12.0k3.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Forbion Growth Opportunities Fund II Cooperatief U.A. 13G · passive investor new · filed 2024-12-19 | 7.3% |
| ARMISTICE CAPITAL, LLC 13G · institution no change · filed 2026-08-14 | 6.7% |
| Long Focus Capital Management, LLC 13G · institution new · filed 2026-05-15 | 6.6% |
Fell to 5% or below in the last year: Invus Global Management, LLC (3.1%, 2026-05-04), WESTFIELD CAPITAL MANAGEMENT CO LP (0.0%, 2026-03-04)
Insider purchases and sales in Q2 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 3 | $9.4m | — |
| Q1 2022 | 0 | — | 0 | — | — |
| Q2 2022 | 0 | — | 0 | — | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 0 | — | — |
| Q1 2023 | 0 | — | 7 | $332.2k | — |
| Q2 2023 | 0 | — | 6 | $55.5k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2023-04-03 | Lee Kevin Chief Executive Officer, director | Sold | $31.4k1.5k shares |
| 2023-04-03 | Crockett Nigel Chief Business Officer | Sold | $9.4k447 shares |
| 2023-04-03 | Milnes Alistair Chief Operating Officer | Sold | $9.4k447 shares |
| 2023-04-03 | Skynner Michael Chief Technology Officer | Sold | $9.4k447 shares |
| 2023-04-03 | Kalowski Lee President and CFO | Sold | $7.9k376 shares |
| 2023-04-03 | Keen Nicholas Chief Scientific Officer | Sold | $6.7k319 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2023
| Manager | Shares | Change |
|---|---|---|
| Deep Track Capital, LP 3.36% of their portfolio | 2.8m $71.9m | Unchanged |
| Paradigm Biocapital Advisors LP 4.10% of their portfolio | 2.0m $50.7m | Added +168.6k |
| Jefferies Financial Group Inc. 1.06% of their portfolio | 1.9m $49.7m | Unchanged |
| First Light Asset Management, LLC 3.48% of their portfolio | 1.7m $44.4m | Added +1.0m |
| MORGAN STANLEY 0.00% of their portfolio | 1.4m $36.7m | Reduced -68.2k |
| TYBOURNE CAPITAL MANAGEMENT (HK) LTD 3.54% of their portfolio | 1.3m $32.7m | Reduced -127.0k |
| JANUS HENDERSON GROUP PLC 0.02% of their portfolio | 1.3m $32.7m | Reduced -193.1k |
| Candriam S.C.A. 0.23% of their portfolio | 1.3m $32.5m | Reduced -29.9k |
| Sio Capital Management, LLC 8.74% of their portfolio | 968.7k $24.7m | Added +1.3k |
| ARMISTICE CAPITAL, LLC 0.56% of their portfolio | 876.0k $22.4m | Added +140.0k |
| BAKER BROS. ADVISORS LP 0.12% of their portfolio | 843.8k $21.5m | Unchanged |
| Polar Capital Holdings Plc 0.13% of their portfolio | 759.5k $19.4m | Reduced -250.0k |
| Verition Fund Management LLC 0.27% of their portfolio | 679.0k $17.3m | Added +96.5k |
| AXA S.A. 0.05% of their portfolio | 553.6k $14.1m | Added +93.5k |
| Logos Global Management LP 1.83% of their portfolio | 520.0k $13.3m | Reduced -230.0k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.04% of their portfolio | 509.3k $13.0m | Reduced -10.3k |
| Point72 Asset Management, L.P. 0.04% of their portfolio | 478.0k $12.2m | Reduced -324.4k |
| Soleus Capital Management, L.P. 1.17% of their portfolio | 411.8k $10.5m | Unchanged |
| NOMURA HOLDINGS INC 0.10% of their portfolio | 400.0k $10.2m | New |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 297.3k $7.6m | Reduced -20.8k |
| FMR LLC 0.00% of their portfolio | 287.1k $7.3m | Reduced -287.1k |
| Rubric Capital Management LP 0.22% of their portfolio | 205.4k $5.2m | Unchanged |
| Ikarian Capital, LLC 1.75% of their portfolio | 203.0k $5.2m | Reduced -4.1k |
| BlackRock Inc. 0.00% of their portfolio | 181.1k $4.6m | Added +2.2k |
| Parkman Healthcare Partners LLC 0.76% of their portfolio | 172.3k $4.4m | Added +24.5k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 139.4k $3.6m | Reduced -48.5k |
| Handelsbanken Fonder AB 0.02% of their portfolio | 134.5k $3.4m | Added +2.7k |
| KENNEDY CAPITAL MANAGEMENT LLC 0.07% of their portfolio | 123.2k $3.1m | New |
| DAFNA Capital Management LLC 0.85% of their portfolio | 122.2k $3.1m | Unchanged |
| ExodusPoint Capital Management, LP 0.03% of their portfolio | 112.0k $2.9m | Reduced -10.8k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 111.2k $2.8m | Added +44.0k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 96.2k $2.5m | Added +9.0k |
| HighVista Strategies LLC 1.08% of their portfolio | 92.4k $2.4m | Unchanged |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 88.4k $2.3m | Added +7.8k |
| GROUP ONE TRADING LLC 0.09% of their portfolio | 84.0k $2.1m | Added +35.5k |
| Legal & General Group Plc 0.00% of their portfolio | 80.3k $2.0m | Added +67.1k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 78.8k $2.0m | Added +61.9k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.04% of their portfolio | 77.9k $2.0m | Reduced -2.8k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 70.9k $1.8m | Added +9.0k |
| SIMPLEX TRADING, LLC 0.07% of their portfolio | 66.4k $1.7m | Added +40.6k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 66.1k $1.7m | Added +6.0k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 62.7k $1.6m | Added +18.1k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 52.6k $1.3m | Reduced -108.0k |
| Tekla Capital Management LLC 0.04% of their portfolio | 44.3k $1.1m | Reduced -44.3k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio | 42.1k $1.1m | Reduced -846 |
| FISHMAN JAY A LTD/MI 0.06% of their portfolio | 41.0k $1.0m | Added +30.5k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 30.0k $720.0k | Added +16.8k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 25.1k $641.5k | Unchanged |
| Bellevue Group AG 0.01% of their portfolio | 25.0k $638.0k | Reduced -28.2k |
| Cubist Systematic Strategies, LLC 0.01% of their portfolio | 24.7k $630.3k | Reduced -19.1k |
| TD Asset Management Inc 0.00% of their portfolio | 23.6k $601.9k | Unchanged |
| HARBOR CAPITAL ADVISORS, INC. 0.11% of their portfolio | 21.0k $537.1k | Added +1.9k |
| WOODSTOCK CORP 0.06% of their portfolio | 20.6k $524.5k | Added +1.9k |
| Allianz Asset Management GmbH 0.00% of their portfolio | 20.4k $521.0k | Reduced -700 |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 18.2k $464.8k | Added +7.7k |
| Jump Financial, LLC 0.02% of their portfolio | 18.2k $463.5k | Reduced -19.6k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 17.1k $437.5k | Unchanged |
| HORIZON KINETICS ASSET MANAGEMENT LLC 0.01% of their portfolio | 15.0k $382.8k | Unchanged |
| AtonRa Partners 0.56% of their portfolio | 14.2k $362.9k | Reduced -950 |
| Erste Asset Management GmbH 0.01% of their portfolio | 14.0k $348.7k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 12.6k $321.9k | Reduced -1.3k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 9.3k $236.6k | Reduced -67.4k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.02% of their portfolio | 9.1k $231.2k | Reduced -3.6k |
| STATE STREET CORP 0.00% of their portfolio | 8.7k $221.2k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 8.4k $213.6k | Unchanged |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 6.5k $166.7k | Added +613 |
| Cutler Group LLC / CA 0.04% of their portfolio | 6.1k $154.0k | Added +3.1k |
| EXCHANGE TRADED CONCEPTS, LLC 0.00% of their portfolio | 5.3k $134.6k | New |
| BIT Capital GmbH 0.01% of their portfolio | 4.8k $123.8k | New |
| HighMark Wealth Management LLC 0.08% of their portfolio | 4.2k $108.1k | Unchanged |
| VIRTUS ADVISERS, LLC 0.06% of their portfolio | 4.1k $104.0k | Added +929 |
| NATIXIS 0.00% of their portfolio | 2.8k $69.9k | Reduced -625 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 2.4k $61.8k | Added +1.2k |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 2.3k $59.2k | Added +1.3k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 684 $17.5k | Reduced -169 |
| CITIGROUP INC 0.00% of their portfolio | 603 $15.4k | Added +148 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 382 $10.0k | Added +189 |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 380 $9.7k | New |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 339 $8.7k | Reduced -10 |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 189 $4.8k | Reduced -7.1k |
| Raleigh Capital Management Inc. 0.00% of their portfolio | 185 $4.7k | New |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 103 $3.0k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 84 $2.1k | Unchanged |
| NFSG Corp 0.00% of their portfolio | 40 $1.0k | Unchanged |
| Bell Investment Advisors, Inc 0.00% of their portfolio | 37 $945 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |