AVROBIO INC
COM · CUSIP 05455M100
46
institutional holders
-8 vs Q3 2022
20.8m
shares reported held*
$14.8mreported value*
5 new
8 added
15 reduced
14 sold out
net sold ≈ $2.6m (-3.6m shares)
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $0.71. Options: 2 managers hold calls ($4.9k notional), 2 hold puts ($143).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 54 |
| Q4 2022 | 46 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
CallsPuts
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $0 | $0 | — |
| Q4 2022 | $4.9k | $143 | 0.03 |
Biggest buyers
| NATIXIS | New | +880.0k |
| ACADIAN ASSET MANAGEMENT LLC | Added | +288.1k |
| Privium Fund Management (UK) Ltd | Added | +153.7k |
| LPL Financial LLC | New | +122.6k |
| CITADEL ADVISORS LLC | Added | +70.8k |
| MORGAN STANLEY | Added | +31.7k |
| JANE STREET GROUP, LLC | New | +29.0k |
| BAILARD, INC. | New | +25.8k |
| TWO SIGMA SECURITIES, LLC | New | +14.2k |
| Tower Research Capital LLC (TRC) | Added | +4.3k |
Biggest sellers
| K2 PRINCIPAL FUND, L.P. | Sold out | -2.7m |
| GOLDMAN SACHS GROUP INC | Reduced | -696.8k |
| BlackRock Inc. | Reduced | -483.2k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -359.9k |
| GMT Capital Corp | Reduced | -184.6k |
| GSA CAPITAL PARTNERS LLP | Sold out | -177.3k |
| D. E. Shaw & Co., Inc. | Sold out | -97.6k |
| TWO SIGMA INVESTMENTS, LP | Reduced | -74.8k |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | Sold out | -68.8k |
| Ergoteles LLC | Reduced | -62.8k |
Biggest calls
| CITADEL ADVISORS LLC | New | $4.9k6.9k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $143200 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| Atlas Venture Life Science Advisors, LLC 0.39% of their portfolio | 4.5m $3.2m | Unchanged |
| GMT Capital Corp 0.11% of their portfolio | 3.3m $2.4m | Reduced -184.6k |
| BlackRock Inc. 0.00% of their portfolio | 1.5m $1.1m | Reduced -483.2k |
| ACADIAN ASSET MANAGEMENT LLC 0.01% of their portfolio | 1.5m $1.0m | Added +288.1k |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.2m $825.7k | Added +943 |
| Aisling Capital Management LP 0.47% of their portfolio | 1.0m $716.9k | Unchanged |
| NATIXIS 0.00% of their portfolio | 880.0k $627.4k | New |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 862.3k $615.0k | Reduced -359.9k |
| FARALLON CAPITAL MANAGEMENT, L.L.C. 0.00% of their portfolio | 740.0k $527.5k | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 688.7k $491.0k | Reduced -20.9k |
| MPM BIOIMPACT LLC 0.12% of their portfolio | 647.9k $461.9k | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 583.0k $415.6k | Added +70.8k |
| MORGAN STANLEY 0.00% of their portfolio | 543.4k $387.4k | Added +31.7k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 385.9k $275.0k | Reduced -943 |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 341.8k $243.7k | Reduced -50.4k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 317.9k $226.6k | Reduced -74.8k |
| New Leaf Venture Partners, L.L.C. 0.16% of their portfolio | 315.6k $225.0k | Unchanged |
| SVB WEALTH LLC 0.00% of their portfolio | 284.4k $202.7k | Unchanged |
| Privium Fund Management (UK) Ltd 0.14% of their portfolio | 263.3k $187.7k | Added +153.7k |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 156.0k $111.2k | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 140.9k $100.4k | Unchanged |
| LPL Financial LLC 0.00% of their portfolio | 122.6k $87.4k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 89.5k $63.8k | Reduced -5.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 73.9k $52.7k | Unchanged |
| Ergoteles LLC 0.00% of their portfolio | 46.9k $33.4k | Reduced -62.8k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 37.2k $26.5k | Unchanged |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 35.0k $25.0k | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 29.0k $20.7k | New |
| BAILARD, INC. 0.00% of their portfolio | 25.8k $18.4k | New |
| NEEDHAM INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 24.5k $17.5k | Unchanged |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 23.6k $17.0k | Reduced -45.1k |
| BARCLAYS PLC 0.00% of their portfolio | 21.9k $15.6k | First filing |
| Colonial River Investments, LLC 0.01% of their portfolio | 16.9k $12.1k | Unchanged |
| Bank of New York Mellon Corp 0.00% of their portfolio | 16.8k $12.0k | Unchanged |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 16.6k $11.6k | Reduced -276 |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 15.1k $11.0k | Added +4.3k |
| TWO SIGMA SECURITIES, LLC 0.00% of their portfolio | 14.2k $10.1k | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 10.1k $7.2k | Reduced -696.8k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 7.2k $5.1k | Reduced -2.4k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 4.6k $3.3k | Added +328 |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 3.0k $2.1k | Unchanged |
| CWM, LLC 0.00% of their portfolio | 2.0k $1.0k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 1.9k $1.0k | Reduced -392 |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 101 $72 | Added +24 |
| UBS Group AG 0.00% of their portfolio | 65 $46 | Reduced -22.4k |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |