AUTOLUS THERAPEUTICS PLC AUTL
SPON ADS · ADR · CUSIP 05280R100 · ISIN US05280R1005
Company in London, United Kingdom
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersUnited Kingdom
- Founded2014
- Websiteautolus.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $1.99. Options: 4 managers hold calls ($583.1k notional), 1 hold puts ($19.9k).
Trends to Q4 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 67 |
| Q4 2022 | 72 |
| Q1 2023 | 66 |
| Q2 2023 | 70 |
| Q3 2023 | 72 |
| Q4 2023 | 100 |
| Q1 2024 | 121 |
| Q2 2024 | 112 |
| Q3 2024 | 102 |
| Q4 2024 | 111 |
| Q1 2025 | 96 |
| Q2 2025 | 95 |
| Q3 2025 | 96 |
| Q4 2025 | 89 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2024 | 73 | 33 |
| Q2 2024 | 54 | 54 |
| Q3 2024 | 37 | 52 |
| Q4 2024 | 52 | 45 |
| Q1 2025 | 37 | 55 |
| Q2 2025 | 50 | 46 |
| Q3 2025 | 47 | 34 |
| Q4 2025 | 35 | 48 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2025 | $86.6k | $145.1k | 1.68 |
| Q2 2025 | $84.0k | $130.9k | 1.56 |
| Q3 2025 | $487.5k | $98.1k | 0.20 |
| Q4 2025 | $583.1k | $19.9k | 0.03 |
Biggest buyers
| MAK CAPITAL ONE LLC | Added | +4.0m |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | New | +3.4m |
| ARMISTICE CAPITAL, LLC | Added | +1.9m |
| SCHRODER INVESTMENT MANAGEMENT GROUP | Added | +1.1m |
| UBS Group AG | Added | +466.4k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | +363.2k |
| Point72 Asset Management, L.P. | New | +305.4k |
| Cetera Investment Advisers | Added | +298.5k |
| BlackRock, Inc. | Added | +211.1k |
| MORGAN STANLEY | Added | +183.5k |
Biggest sellers
| CITADEL ADVISORS LLC | Reduced | -4.9m |
| Deep Track Capital, LP | Sold out | -2.6m |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -1.8m |
| Affinity Asset Advisors, LLC | Sold out | -1.8m |
| JPMORGAN CHASE & CO | Reduced | -826.9k |
| Perpetual Ltd | Sold out | -481.1k |
| GOLDMAN SACHS GROUP INC | Reduced | -466.0k |
| MILLENNIUM MANAGEMENT LLC | Sold out | -391.8k |
| MARSHALL WACE, LLP | Reduced | -371.7k |
| Quadrature Capital Ltd | Reduced | -314.9k |
Biggest calls
| GROUP ONE TRADING LLC | Reduced | $409.3k205.7k shares |
| CITADEL ADVISORS LLC | Added | $109.3k54.9k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $34.4k17.3k shares |
| SIMPLEX TRADING, LLC | Reduced | $30.0k15.1k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $19.9k10.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| MAK Capital Fund LP 13G · exempt (held before listing) +1.3 pts · filed 2026-05-15 | 12.6% |
| Syncona Portfolio Ltd 13G · exempt (held before listing) filed 2025-05-07 | 10.8% |
| ARMISTICE CAPITAL, LLC 13G · institution -0.3 pts · filed 2026-08-14 | 5.6% |
PPF Group a.s.
13D · may seek influence
filed 2026-08-28
Stated purposeItem 4 of the Schedule 13D is hereby amended and supplemented to include the following: The transactions described in this Amendment No. 11 were undertaken solely to effect an internal reorganization of the PPF group of companies. Such transactions did not involve any change in the ultimate beneficial ownership of, or the ultimate voting or dispositive power over, the Ordinary Shares reported herein, and were not undertaken with any purpose of, or with the effect of, changing or influencing control of the Issuer. Other than as described herein, the Reporting Persons do not have any current plans or proposals which relate to or would result in any of the actions described in subparagraphs (a) through (j) above. Full filing |
5.6% |
Insider purchases and sales in Q4 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q4 2025.
Holders, Q4 2025
| Manager | Shares | Change |
|---|---|---|
| MAK CAPITAL ONE LLC 8.03% of their portfolio | 30.0m $59.7m | Added +4.0m |
| Blackstone Inc. 0.18% of their portfolio | 20.5m $40.8m | Unchanged |
| ARMISTICE CAPITAL, LLC 0.85% of their portfolio | 17.5m $34.8m | Added +1.9m |
| Syncona Portfolio Ltd 96.48% of their portfolio | 16.6m $33.1m | Unchanged |
| Tetragon Partners GP Ltd 3.99% of their portfolio | 9.5m $18.9m | Unchanged |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.01% of their portfolio | 9.5m $18.7m | Added +1.1m |
| Frazier Life Sciences Management, L.P. 0.25% of their portfolio | 4.6m $9.2m | Unchanged |
| BlackRock, Inc. 0.00% of their portfolio | 3.7m $7.3m | Added +211.1k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.01% of their portfolio | 3.4m $6.7m | New |
| Laurion Capital Management LP 0.45% of their portfolio | 3.3m $6.6m | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 3.1m $6.2m | Reduced -1.8m |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 2.0m $3.9m | Reduced -68.8k |
| ACADIAN ASSET MANAGEMENT LLC 0.01% of their portfolio | 1.8m $3.6m | Reduced -49.3k |
| MORGAN STANLEY 0.00% of their portfolio | 1.4m $2.8m | Added +183.5k |
| Atle Fund Management AB 0.74% of their portfolio | 1.2m $2.3m | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 1.2m $2.3m | Reduced -4.9m |
| Cetera Investment Advisers 0.00% of their portfolio | 1.1m $2.2m | Added +298.5k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 979.3k $1.9m | Reduced -826.9k |
| UBS Group AG 0.00% of their portfolio | 877.1k $1.7m | Added +466.4k |
| Alphabet Inc. 0.05% of their portfolio | 698.3k $1.4m | Unchanged |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 681.0k $1.4m | Reduced -193.5k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 599.0k $1.2m | Added +363.2k |
| Hennion & Walsh Asset Management, Inc. 0.03% of their portfolio | 453.8k $903.1k | Added +33.2k |
| Privium Fund Management B.V. 0.12% of their portfolio | 326.2k $649.2k | Added +17.4k |
| Point72 Asset Management, L.P. 0.00% of their portfolio | 305.4k $607.7k | New |
| EDENTREE ASSET MANAGEMENT Ltd 0.18% of their portfolio | 300.0k $594.0k | Unchanged |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 282.1k $561.4k | Added +75.5k |
| MARSHALL WACE, LLP 0.00% of their portfolio | 270.3k $537.9k | Reduced -371.7k |
| Aubrey Capital Management Ltd 0.18% of their portfolio | 225.2k $445.0k | Reduced -9.3k |
| Diametric Capital, LP 0.11% of their portfolio | 199.9k $397.8k | Reduced -57.3k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 197.1k $392.2k | Reduced -34.0k |
| Erste Asset Management GmbH 0.00% of their portfolio | 195.0k $364.6k | Unchanged |
| DAFNA Capital Management LLC 0.08% of their portfolio | 179.3k $356.8k | Unchanged |
| Arizona PSPRS Trust 0.01% of their portfolio | 150.0k $298.5k | New |
| HighPoint Advisor Group LLC 0.01% of their portfolio | 139.8k $278.2k | Added +51.5k |
| Rathbones Group PLC 0.00% of their portfolio | 130.0k $258.7k | Added +65.0k |
| XTX Topco Ltd 0.01% of their portfolio | 129.2k $257.2k | Reduced -128.1k |
| Caitong International Asset Management Co., Ltd 0.06% of their portfolio | 123.3k $245.3k | Added +94.9k |
| Clearstead Advisors, LLC 0.00% of their portfolio | 121.1k $241.0k | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.02% of their portfolio | 119.5k $238.0k | New |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P 0.19% of their portfolio | 112.5k $223.9k | First filing |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 110.6k $220.1k | Reduced -53.7k |
| Leonteq Securities AG 0.01% of their portfolio | 100.0k $199.0k | Unchanged |
| OpenArc Corporate Advisory, LLC 0.00% of their portfolio | 84.8k $168.9k | First filing |
| STATE STREET CORP 0.00% of their portfolio | 81.8k $162.8k | Reduced -1.3k |
| SG Americas Securities, LLC 0.00% of their portfolio | 66.7k $133.0k | Added +26.2k |
| TWO SIGMA SECURITIES, LLC 0.02% of their portfolio | 66.6k $132.5k | New |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 57.9k $115.3k | Added +44.4k |
| Avanza Fonder AB 0.00% of their portfolio | 53.5k $106.5k | Unchanged |
| Invesco Ltd. 0.00% of their portfolio | 51.6k $102.8k | Added +13.6k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 49.9k $99.2k | Added +11.4k |
| Scientech Research LLC 0.06% of their portfolio | 48.6k $96.7k | New |
| LPL Financial LLC 0.00% of their portfolio | 42.6k $84.8k | Reduced -91.4k |
| Quadrature Capital Ltd 0.00% of their portfolio | 42.3k $84.3k | Reduced -314.9k |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 32.7k $65.0k | Reduced -2.5k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 32.3k $64.2k | Added +15.9k |
| PRELUDE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 32.0k $63.7k | Reduced -39.2k |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 31.3k $62.3k | New |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 0.00% of their portfolio | 30.1k $59.9k | Reduced -27.7k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 27.7k $55.2k | Reduced -466.0k |
| FOREFRONT WEALTH MANAGEMENT INC. 0.04% of their portfolio | 26.9k $53.5k | Unchanged |
| R Squared Ltd 0.02% of their portfolio | 26.7k $53.1k | Reduced -3.8k |
| Delaney Dennis R 0.02% of their portfolio | 24.0k $47.8k | Unchanged |
| SmartHarvest Portfolios, LLC 0.01% of their portfolio | 21.4k $42.5k | First filing |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 20.1k $39.9k | Added +500 |
| Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio | 17.7k $35.3k | Reduced -2.4k |
| DUMONT & BLAKE INVESTMENT ADVISORS LLC 0.01% of their portfolio | 15.0k $30.0k | Unchanged |
| SIH Partners, LLLP 0.00% of their portfolio | 14.9k $29.6k | Added +4.0k |
| Independent Advisor Alliance 0.00% of their portfolio | 13.9k $27.6k | New |
| GAMMA Investing LLC 0.00% of their portfolio | 10.2k $20.3k | Added +774 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 10.0k $20.0k | Reduced -11.9k |
| WEALTH EFFECTS LLC 0.01% of their portfolio | 10.0k $19.9k | Reduced -6.0k |
| Icon Wealth Advisors, LLC 0.00% of their portfolio | 10.0k $19.9k | New |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 9.7k $19.4k | Added +2.0k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 8.4k $16.8k | Reduced -1.8k |
| TrinityBridge Ltd 0.00% of their portfolio | 6.3k $13.0k | Unchanged |
| CITIGROUP INC 0.00% of their portfolio | 5.9k $11.8k | Added +2.1k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 4.8k $9.5k | Added +2.1k |
| GF FUND MANAGEMENT CO. LTD. 0.00% of their portfolio | 3.9k $7.8k | Reduced -320 |
| Garton & Associates Financial Advisors LLC 0.00% of their portfolio | 600 $1.2k | First filing |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 575 $1.0k | Unchanged |
| CALDWELL SUTTER CAPITAL, INC. 0.00% of their portfolio | 500 $995 | Unchanged |
| MAI Capital Management 0.00% of their portfolio | 189 $377 | Reduced -3.9k |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 163 $324 | Reduced -1.5k |
| Byrne Asset Management LLC 0.00% of their portfolio | 100 $199 | Reduced -125 |
| SageView Advisory Group, LLC 0.00% of their portfolio | 75 $150 | New |
| Allworth Financial LP 0.00% of their portfolio | 50 $100 | Unchanged |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 50 $100 | Reduced -1 |
| HUNTINGTON NATIONAL BANK 0.00% of their portfolio | 1 $2 | Unchanged |