LEONABIO INC LONA
COM · Common Stock · CUSIP 04746L203
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersBothell, WA
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.4m this quarter). Holder counts are more reliable. Shares outstanding: 9.4m as of 2026-08-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $9.19.
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2025 | 34 |
| Q4 2025 | 42 |
| Q1 2026 | 40 |
| Q2 2026 | 44 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2025 | 20 | 13 |
| Q1 2026 | 15 | 12 |
| Q2 2026 | 14 | 10 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $2.5k | $0 | 0.00 |
| Q4 2025 | $0 | $0 | — |
| Q1 2026 | $0 | $0 | — |
| Q2 2026 | $0 | $0 | — |
Biggest buyers
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | +300.0k |
| VANGUARD CAPITAL MANAGEMENT LLC | Added | +80.5k |
| ADAR1 Capital Management, LLC | Added | +49.6k |
| BlackRock, Inc. | Added | +23.1k |
| DIMENSIONAL FUND ADVISORS LP | New | +14.7k |
| RENAISSANCE TECHNOLOGIES LLC | Added | +13.2k |
| XTX Topco Ltd | New | +11.7k |
| CITADEL ADVISORS LLC | New | +10.0k |
| VANGUARD FIDUCIARY TRUST CO | Added | +2.8k |
| JPMORGAN CHASE & CO | Added | +2.0k |
Biggest sellers
| Seven Fleet Capital Management LP | Reduced | -10.5k |
| OSAIC HOLDINGS, INC. | Reduced | -1.6k |
| ROYAL BANK OF CANADA | Reduced | -1.4k |
| UBS Group AG | Reduced | -1.1k |
| Annis Gardner Whiting Capital Advisors, LLC | Sold out | -1.0k |
| NewEdge Advisors, LLC | Sold out | -410 |
| MORGAN STANLEY | Reduced | -382 |
| BANK OF AMERICA CORP /DE/ | Reduced | -9 |
| BNP PARIBAS FINANCIAL MARKETS | Reduced | -3 |
| CITIGROUP INC | Sold out | -1 |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
Sermonix Pharmaceuticals, Inc.
13D · may seek influence
-11.8 pts · filed 2026-10-28
Stated purposeThe assignment of the remaining prefunded warrant rights to acquire 2,352,932 common shares of Issuer effects the previously disclosed distribution-in-kind to PXV II as part of the plan of distribution to the owners of Sermonix's common stock as described in the original Schedule 13D and Item 5. Full filing |
25.1% |
| PERCEPTIVE ADVISORS LLC 13D · may seek influence no change · filed 2026-10-26 | 20.0% |
| ACORN BIOVENTURES, L.P. 13G · passive investor filed 2026-08-20 | 12.1% |
| ADAR1 Capital Management, LLC 13G · institution new · filed 2026-05-15 | 7.7% |
Fell to 5% or below in the last year: Baselake Partners, LP (1.9%, 2026-02-06)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 5 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 5 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 5 | $93.4k | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 0 | — | — |
None reported since 1 Apr 2026.
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| PERCEPTIVE ADVISORS LLC 0.27% of their portfolio | 1.9m $17.1m | Unchanged |
| Kalehua Capital Management LLC 2.31% of their portfolio | 787.4k $7.2m | Unchanged |
| ADAR1 Capital Management, LLC 0.34% of their portfolio | 777.1k $7.1m | Added +49.6k |
| ACORN CAPITAL ADVISORS, LLC 1.59% of their portfolio | 634.5k $5.8m | Unchanged |
| NEA Management Company, LLC 0.27% of their portfolio | 464.4k $4.3m | Unchanged |
| Commodore Capital LP 0.25% of their portfolio | 464.4k $4.3m | Unchanged |
| TCG Crossover Management, LLC 0.10% of their portfolio | 464.4k $4.3m | Unchanged |
| Spruce Street Capital LP 0.71% of their portfolio | 393.7k $3.6m | Unchanged |
| Blackstone Inc. 0.01% of their portfolio | 324.6k $3.0m | Not comparable |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio | 300.0k $2.8m | New |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 275.2k $2.5m | Added +80.5k |
| Seven Fleet Capital Management LP 0.23% of their portfolio | 154.2k $1.4m | Reduced -10.5k |
| Simplify Asset Management Inc. 0.02% of their portfolio | 149.3k $1.4m | Unchanged |
| Propel Bio Management, LLC 0.72% of their portfolio | 149.3k $1.4m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 80.4k $739.5k | Added +95 |
| BlackRock, Inc. 0.00% of their portfolio | 79.2k $727.7k | Added +23.1k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 77.4k $711.5k | Added +13.2k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 42.8k $393.5k | Added +2.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 32.6k $299.2k | Reduced -9 |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 32.5k $298.2k | Added +772 |
| Laird Norton Wetherby Trust Company, LLC 0.00% of their portfolio | 21.8k $200.5k | Unchanged |
| STATE STREET CORP 0.00% of their portfolio | 16.3k $150.1k | Unchanged |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 14.7k $135.4k | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 14.4k $132.3k | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 13.3k $122.0k | Unchanged |
| XTX Topco Ltd 0.00% of their portfolio | 11.7k $108.0k | New |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 10.2k $94.0k | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 10.0k $91.9k | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 4.6k $42.1k | Reduced -1.6k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 2.0k $17.8k | Added +2.0k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 1.3k $12.2k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 844 $8.0k | Reduced -1.4k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 438 $4.0k | New |
| American Capital Advisory, LLC 0.00% of their portfolio | 200 $1.8k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 196 $1.8k | Reduced -1.1k |
| ROTHSCHILD INVESTMENT LLC 0.00% of their portfolio | 150 $1.4k | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 89 $818 | Reduced -382 |
| US BANCORP \DE\ 0.00% of their portfolio | 81 $744 | Unchanged |
| Global Retirement Partners, LLC 0.00% of their portfolio | 52 $477 | First filing |
| BARCLAYS PLC 0.00% of their portfolio | 42 $386 | New |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 33 $310 | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 20 $184 | Reduced -3 |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 12 $110 | Unchanged |
| Caitong International Asset Management Co., Ltd 0.00% of their portfolio | 6 $55 | Unchanged |