Vault-13

ASTRAZENECA PLC

SPONSORED ADR · ADR · CUSIP 046353108 · ISIN US0463531089

1,219 institutional holders -30 vs Q1 2025
498,329,113498.3m shares reported held*
$34.8bnreported value*
80 new 460 added 439 reduced 111 sold out net sold ≈ $760.3m (-8.6m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($84.4m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $69.90. Options: 25 managers hold calls ($595.6m notional), 24 hold puts ($258.8m).

Trends to Q2 2025

Institutional holders

Managers reporting a position, each quarter

05001k1.5kQ3 22: 966Q4 22: 1,061Q1 23: 1,056Q2 23: 1,091Q3 23: 1,075Q4 23: 1,128Q1 24: 1,138Q2 24: 1,212Q3 24: 1,228Q4 24: 1,216Q1 25: 1,249Q2 25: 1,2191,219Q3 22Q2 23Q1 24Q4 24Q2 25
Numbers
QuarterHolders
Q3 2022966
Q4 20221,061
Q1 20231,056
Q2 20231,091
Q3 20231,075
Q4 20231,128
Q1 20241,138
Q2 20241,212
Q3 20241,228
Q4 20241,216
Q1 20251,249
Q2 20251,219

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
1k01kQ3 23: 510 bought or addedQ3 23: 421 cut or sold outQ4 23: 475 bought or addedQ4 23: 435 cut or sold outQ4 23Q1 24: 592 bought or addedQ1 24: 434 cut or sold outQ2 24: 643 bought or addedQ2 24: 399 cut or sold outQ2 24Q3 24: 605 bought or addedQ3 24: 490 cut or sold outQ4 24: 514 bought or addedQ4 24: 583 cut or sold outQ4 24Q1 25: 657 bought or addedQ1 25: 467 cut or sold outQ2 25: 540 bought or addedQ2 25: 550 cut or sold outQ2 25
Numbers
QuarterBought or addedCut or sold out
Q3 2023510421
Q4 2023475435
Q1 2024592434
Q2 2024643399
Q3 2024605490
Q4 2024514583
Q1 2025657467
Q2 2025540550

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$250m$500m$750m$1bnQ3 24 calls: $490.0mQ3 24 puts: $338.3mQ3 24P/C 0.69Q4 24 calls: $490.9mQ4 24 puts: $353.6mQ4 24P/C 0.72Q1 25 calls: $854.6mQ1 25 puts: $293.5mQ1 25P/C 0.34Q2 25 calls: $595.6mQ2 25 puts: $258.8mQ2 25P/C 0.43
Numbers
QuarterCallsPutsP/C
Q3 2024$490.0m$338.3m0.69
Q4 2024$490.9m$353.6m0.72
Q1 2025$854.6m$293.5m0.34
Q2 2025$595.6m$258.8m0.43

Biggest buyers

ROYAL BANK OF CANADA Added +4,377,078+4.4m
Fayez Sarofim & Co Added +2,376,032+2.4m
ACADIAN ASSET MANAGEMENT LLC Added +1,961,764+2.0m
JENNISON ASSOCIATES LLC Added +1,605,133+1.6m
RAYMOND JAMES FINANCIAL INC Added +1,487,662+1.5m
ONTARIO TEACHERS PENSION PLAN BOARD New +1,387,174+1.4m
RENAISSANCE TECHNOLOGIES LLC Added +1,004,573+1.0m
DIMENSIONAL FUND ADVISORS LP Added +918,820+918.8k
Clearbridge Investments, LLC Added +864,772+864.8k
WOODLEY FARRA MANION PORTFOLIO MANAGEMENT INC New +760,436+760.4k

Biggest sellers

PRICE T ROWE ASSOCIATES INC /MD/ Reduced -5,143,918-5.1m
MORGAN STANLEY Reduced -3,551,867-3.6m
VOYA INVESTMENT MANAGEMENT LLC Reduced -3,285,125-3.3m
SOROS FUND MANAGEMENT LLC Sold out -2,742,498-2.7m
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP Reduced -2,436,044-2.4m
FMR LLC Reduced -1,750,753-1.8m
BANK OF MONTREAL /CAN/ Reduced -1,452,771-1.5m
WCM INVESTMENT MANAGEMENT, LLC Reduced -1,349,988-1.3m
WELLINGTON MANAGEMENT GROUP LLP Reduced -1,293,399-1.3m
GQG Partners LLC Reduced -1,247,762-1.2m

Biggest calls

CITADEL ADVISORS LLC Added $159.0m2.3m shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $87.4m1.3m shares
PUBLIC INVESTMENT FUND Added $70.9m1.0m shares
Optiver Holding B.V. Added $58.0m830.1k shares
BARCLAYS PLC Added $50.7m725.0k shares
Twin Tree Management, LP Reduced $33.8m484.3k shares
JANE STREET GROUP, LLC Reduced $25.4m363.6k shares
Squarepoint Ops LLC Added $14.8m211.1k shares
SIMPLEX TRADING, LLC Reduced $14.7m210.4k shares
IMC-Chicago, LLC Reduced $14.7m210.0k shares

Biggest puts

Optiver Holding B.V. Added $58.9m843.5k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $52.6m752.5k shares
CITADEL ADVISORS LLC Added $25.2m361.3k shares
Qube Research & Technologies Ltd Reduced $18.8m269.6k shares
Squarepoint Ops LLC Reduced $16.0m228.3k shares
Walleye Trading LLC Added $15.0m215.3k shares
MILLENNIUM MANAGEMENT LLC Reduced $12.3m175.8k shares
IMC-Chicago, LLC Reduced $11.7m167.8k shares
JANE STREET GROUP, LLC Added $11.5m164.0k shares
SIMPLEX TRADING, LLC Reduced $9.2m131.6k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Holders, Q2 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 PRICE T ROWE ASSOCIATES INC /MD/ 0.41% of their portfolio BALTIMORE, MD 51,942,96351.9m $3.6bn $3.6bn 0.41% Reduced -5.1m -5,143,918
2 PRIMECAP MANAGEMENT CO/CA/ 2.28% of their portfolio PASADENA, CA 41,200,09141.2m $2.9bn $2.9bn 2.28% Added +538.6k +538,606
3 WELLINGTON MANAGEMENT GROUP LLP 0.44% of their portfolio Boston, MA 34,337,28134.3m $2.4bn $2.4bn 0.44% Reduced -1.3m -1,293,399
4 Capital International Investors 0.38% of their portfolio Los Angeles, CA 31,404,98331.4m $2.2bn $2.2bn 0.38% Added +119.4k +119,423
5 BANK OF AMERICA CORP /DE/ 0.18% of their portfolio CHARLOTTE, NC 31,171,35331.2m $2.2bn $2.2bn 0.18% Reduced -661.7k -661,662
6 FMR LLC 0.08% of their portfolio BOSTON, MA 21,341,71821.3m $1.5bn $1.5bn 0.08% Reduced -1.8m -1,750,753
7 FRANKLIN RESOURCES INC 0.39% of their portfolio San Mateo, CA 21,298,39421.3m $1.5bn $1.5bn 0.39% Added +196.4k +196,401
8 Fisher Asset Management, LLC 0.57% of their portfolio PLANO, TX 20,695,97920.7m $1.4bn $1.4bn 0.57% Added +530.5k +530,520
9 Sanders Capital, LLC 1.36% of their portfolio West Palm Beach, FL 14,526,86214.5m $1.0bn $1.0bn 1.36% Reduced -542.1k -542,124
10 MORGAN STANLEY 0.06% of their portfolio NEW YORK, NY 12,216,66912.2m $853.7m $853.7m 0.06% Reduced -3.6m -3,551,867
11 JENNISON ASSOCIATES LLC 0.50% of their portfolio NEW YORK, NY 12,167,36512.2m $850.3m $850.3m 0.50% Added +1.6m +1,605,133
12 GOLDMAN SACHS GROUP INC 0.14% of their portfolio NEW YORK, NY 12,012,06212.0m $839.4m $839.4m 0.14% Added +230.2k +230,214
13 CIBC Private Wealth Group LLC 1.03% of their portfolio ATLANTA, GA 8,232,3618.2m $575.3m $575.3m 1.03% Added +13.5k +13,498
14 ROYAL BANK OF CANADA 0.05% of their portfolio TORONTO, A6 6,906,4726.9m $482.6m $482.6m 0.05% Added +4.4m +4,377,078
15 DIMENSIONAL FUND ADVISORS LP 0.10% of their portfolio AUSTIN, TX 6,223,7136.2m $434.9m $434.9m 0.10% Added +918.8k +918,820
16 BlackRock, Inc. 0.01% of their portfolio New York, NY 5,487,5245.5m $383.5m $383.5m 0.01% Added +96.5k +96,454
17 AMERIPRISE FINANCIAL INC 0.09% of their portfolio MINNEAPOLIS, MN 5,046,9925.0m $351.7m $351.7m 0.09% Added +104.6k +104,625
18 NEUBERGER BERMAN GROUP LLC 0.27% of their portfolio NEW YORK, NY 4,994,1985.0m $349.0m $349.0m 0.27% Reduced -1.0m -1,014,806
19 Boston Partners 0.39% of their portfolio BOSTON, MA 4,989,9245.0m $349.9m $349.9m 0.39% Reduced -46.7k -46,721
20 NORTHERN TRUST CORP 0.04% of their portfolio CHICAGO, IL 4,529,0004.5m $316.5m $316.5m 0.04% Reduced -137.8k -137,777
21 Clearbridge Investments, LLC 0.25% of their portfolio NEW YORK, NY 4,353,3544.4m $304.2m $304.2m 0.25% Added +864.8k +864,772
22 Holocene Advisors, LP 0.74% of their portfolio New York, NY 4,321,6294.3m $302.0m $302.0m 0.74% Reduced -124.8k -124,752
23 Swedbank AB 0.32% of their portfolio STOCKHOLM, V7 4,077,5544.1m $284.9m $284.9m 0.32% First filing
24 Invesco Ltd. 0.05% of their portfolio ATLANTA, GA 3,861,2103.9m $269.8m $269.8m 0.05% Added +53.7k +53,688
25 RAYMOND JAMES FINANCIAL INC 0.09% of their portfolio ST. PETERSBURG, FL 3,783,2513.8m $264.4m $264.4m 0.09% Added +1.5m +1,487,662
26 JPMORGAN CHASE & CO 0.02% of their portfolio NEW YORK, NY 3,775,3343.8m $263.8m $263.8m 0.02% Reduced -819.5k -819,494
27 Fayez Sarofim & Co 0.63% of their portfolio Houston, TX 3,745,9023.7m $261.8m $261.8m 0.63% Added +2.4m +2,376,032
28 ENVESTNET ASSET MANAGEMENT INC 0.07% of their portfolio Berwyn, PA 3,553,5543.6m $248.3m $248.3m 0.07% Reduced -189.5k -189,512
29 WELLS FARGO & COMPANY/MN 0.05% of their portfolio SAN FRANCISCO, CA 3,228,5063.2m $225.6m $225.6m 0.05% Added +99.4k +99,429
30 WCM INVESTMENT MANAGEMENT, LLC 0.42% of their portfolio LAGUNA BEACH, CA 2,653,0822.7m $185.3m $185.3m 0.42% Reduced -1.3m -1,349,988
31 JANUS HENDERSON GROUP PLC 0.09% of their portfolio LONDON, X0 2,531,8102.5m $176.9m $176.9m 0.09% Added +364.6k +364,569
32 UBS Group AG 0.03% of their portfolio ZURICH, V8 2,375,9962.4m $166.0m $166.0m 0.03% Added +666.4k +666,403
33 MANNING & NAPIER ADVISORS LLC 1.79% of their portfolio Fairport, NY 2,152,5352.2m $150.4m $150.4m 1.79% Reduced -902.7k -902,693
34 ALLIANCEBERNSTEIN L.P. 0.05% of their portfolio NASHVILLE, TN 2,084,6262.1m $145.7m $145.7m 0.05% Reduced -102.1k -102,055
35 ACADIAN ASSET MANAGEMENT LLC 0.29% of their portfolio Boston, MA 2,043,8502.0m $142.8m $142.8m 0.29% Added +2.0m +1,961,764
36 MARSHALL WACE, LLP 0.17% of their portfolio LONDON, X0 1,999,9312.0m $139.8m $139.8m 0.17% Added +623.9k +623,902
37 D. E. Shaw & Co., Inc. 0.13% of their portfolio New York, NY 1,904,9431.9m $133.1m $133.1m 0.13% Added +207.2k +207,151
38 NATIXIS ADVISORS, LLC 0.20% of their portfolio Boston, MA 1,837,9251.8m $128.4m $128.4m 0.20% Reduced -398.1k -398,086
39 CITADEL ADVISORS LLC 0.11% of their portfolio MIAMI, FL 1,830,9441.8m $127.9m $127.9m 0.11% Reduced -215.3k -215,277
40 Point72 Asset Management, L.P. 0.28% of their portfolio STAMFORD, CT 1,685,5511.7m $117.8m $117.8m 0.28% Added +497.9k +497,879
41 SATURNA CAPITAL CORP 1.54% of their portfolio BELLINGHAM, WA 1,633,7151.6m $114.2m $114.2m 1.54% Reduced -2.4k -2,380
42 AMERICAN CENTURY COMPANIES INC 0.06% of their portfolio KANSAS CITY, MO 1,560,3261.6m $109.0m $109.0m 0.06% Reduced -460.3k -460,303
43 CRAWFORD INVESTMENT COUNSEL INC 1.88% of their portfolio ATLANTA, GA 1,538,8601.5m $107.5m $107.5m 1.88% Reduced -28.6k -28,637
44 ONTARIO TEACHERS PENSION PLAN BOARD 2.00% of their portfolio Toronto, A6 1,387,1741.4m $96.9m $96.9m 2.00% New
45 Epoch Investment Partners, Inc. 0.48% of their portfolio New York, NY 1,323,2691.3m $92.5m $92.5m 0.48% Reduced -673.4k -673,431
46 RENAISSANCE TECHNOLOGIES LLC 0.12% of their portfolio NEW YORK, NY 1,303,7731.3m $91.1m $91.1m 0.12% Added +1.0m +1,004,573
47 PARNASSUS INVESTMENTS, LLC 0.21% of their portfolio San Francisco, CA 1,286,9791.3m $89.9m $89.9m 0.21% Added +62.2k +62,220
48 PRINCIPAL FINANCIAL GROUP INC 0.04% of their portfolio DES MOINES, IA 1,204,0451.2m $84.1m $84.1m 0.04% Added +5.6k +5,595
49 Assenagon Asset Management S.A. 0.13% of their portfolio SENNINGERBERG, N4 1,167,5161.2m $81.6m $81.6m 0.13% Added +392.8k +392,843
50 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 0.06% of their portfolio BOSTON, MA 1,155,5761.2m $80.8m $80.8m 0.06% Reduced -2.4m -2,436,044
51 STIFEL FINANCIAL CORP 0.08% of their portfolio ST. LOUIS, MO 1,147,8531.1m $80.2m $80.2m 0.08% Reduced -50.7k -50,686
52 MILLENNIUM MANAGEMENT LLC 0.07% of their portfolio NEW YORK, NY 1,144,4551.1m $80.0m $80.0m 0.07% Added +193.2k +193,219
53 NICHOLAS COMPANY, INC. 1.33% of their portfolio MILWAUKEE, WI 1,139,5991.1m $79.6m $79.6m 1.33% Reduced -21.4k -21,410
54 VOYA INVESTMENT MANAGEMENT LLC 0.08% of their portfolio ATLANTA, GA 1,129,0851.1m $78.9m $78.9m 0.08% Reduced -3.3m -3,285,125
55 LAZARD ASSET MANAGEMENT LLC 0.11% of their portfolio NEW YORK, NY 1,126,9101.1m $78.7m $78.7m 0.11% Reduced -1.8k -1,784
56 FIRST TRUST ADVISORS LP 0.06% of their portfolio Wheaton, IL 1,109,4641.1m $77.5m $77.5m 0.06% Added +217.6k +217,595
57 Rockefeller Capital Management L.P. 0.08% of their portfolio NEW YORK, NY 1,027,6701.0m $71.8m $71.8m 0.08% Added +409.5k +409,469
58 Erste Asset Management GmbH 0.59% of their portfolio VIENNA, C4 1,011,9611.0m $70.7m $70.7m 0.59% Added +51.3k +51,313
59 LPL Financial LLC 0.02% of their portfolio FORT MILL, SC 1,000,4191.0m $69.9m $69.9m 0.02% Added +117.3k +117,349
60 CAUSEWAY CAPITAL MANAGEMENT LLC 1.05% of their portfolio LOS ANGELES, CA 953,448953.4k $66.6m $66.6m 1.05% Added +95.6k +95,561
61 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 938,997939.0k $65.6m $65.6m 0.00% Reduced -59.6k -59,558
62 HighTower Advisors, LLC 0.08% of their portfolio CHICAGO, IL 926,278926.3k $64.7m $64.7m 0.08% Added +180.7k +180,680
63 Bank of New York Mellon Corp 0.01% of their portfolio NEW YORK, NY 925,597925.6k $64.7m $64.7m 0.01% Reduced -68.5k -68,487
64 CITIGROUP INC 0.04% of their portfolio NEW YORK, NY 923,998924.0k $64.6m $64.6m 0.04% Added +135.1k +135,107
65 TD Asset Management Inc 0.05% of their portfolio Toronto, A6 908,339908.3k $63.5m $63.5m 0.05% Reduced -199.9k -199,851
66 TWO SIGMA INVESTMENTS, LP 0.11% of their portfolio NEW YORK, NY 858,505858.5k $60.0m $60.0m 0.11% Added +404.0k +403,965
67 Russell Investments Group, Ltd. 0.08% of their portfolio Seattle, WA 857,992858.0k $60.0m $60.0m 0.08% Reduced -64.3k -64,338
68 ProShare Advisors LLC 0.12% of their portfolio BETHESDA, MD 833,661833.7k $58.3m $58.3m 0.12% Added +48.3k +48,255
69 SEI INVESTMENTS CO 0.07% of their portfolio OAKS, PA 814,170814.2k $56.9m $56.9m 0.07% Reduced -875 -875
70 Harvest Portfolios Group Inc. 1.32% of their portfolio Oakville, A6 814,163814.2k $56.9m $56.9m 1.32% Reduced -9.8k -9,798
71 TRUIST FINANCIAL CORP 0.08% of their portfolio CHARLOTTE, NC 813,753813.8k $56.9m $56.9m 0.08% Added +108.3k +108,262
72 Phoenix Financial Ltd. 0.75% of their portfolio Givatayim, L3 811,598811.6k $56.7m $56.7m 0.75% Reduced -344.4k -344,407
73 Aberdeen Group plc 0.09% of their portfolio EDINBURGH, X0 795,584795.6k $55.6m $55.6m 0.09% Added +15.8k +15,793
74 BANK OF MONTREAL /CAN/ 0.03% of their portfolio TORONTO, A6 782,321782.3k $54.7m $54.7m 0.03% Reduced -1.5m -1,452,771
75 Capital Research Global Investors 0.01% of their portfolio Los Angeles, CA 776,953777.0k $54.3m $54.3m 0.01% Added +6.2k +6,185
76 ZWJ INVESTMENT COUNSEL INC 1.98% of their portfolio Atlanta, GA 763,470763.5k $53.4m $53.4m 1.98% Added +14.2k +14,151
77 WOODLEY FARRA MANION PORTFOLIO MANAGEMENT INC 2.50% of their portfolio INDIANAPOLIS, IN 760,436760.4k $53.1m $53.1m 2.50% New
78 BI Asset Management Fondsmaeglerselskab A/S 0.46% of their portfolio KOBENHAVN, G7 717,544717.5k $46.7m $46.7m 0.46% Added +122.9k +122,858
79 BARCLAYS PLC 0.02% of their portfolio LONDON, X0 680,652680.7k $47.6m $47.6m 0.02% Added +92.6k +92,556
80 Qube Research & Technologies Ltd 0.07% of their portfolio LONDON, X0 670,117670.1k $46.8m $46.8m 0.07% Added +446.5k +446,487
81 Clark Capital Management Group, Inc. 0.32% of their portfolio PHILADELPHIA, PA 666,513666.5k $46.6m $46.6m 0.32% Added +275.3k +275,344
82 Mariner, LLC 0.07% of their portfolio Overland Park, KS 662,081662.1k $46.3m $46.3m 0.07% Added +206.5k +206,494
83 Legal & General Group Plc 0.01% of their portfolio London, X0 624,858624.9k $43.7m $43.7m 0.01% Reduced -57.1k -57,065
84 Bridgewater Associates, LP 0.18% of their portfolio Westport, CT 620,904620.9k $43.4m $43.4m 0.18% Reduced -70.2k -70,196
85 CIDEL ASSET MANAGEMENT INC 2.52% of their portfolio TORONTO, A6 599,997600.0k $41.9m $41.9m 2.52% Added +28.3k +28,292
86 TRILLIUM ASSET MANAGEMENT, LLC 1.10% of their portfolio BOSTON, MA 585,898585.9k $40.9m $40.9m 1.10% Reduced -63.5k -63,541
87 BNP PARIBAS FINANCIAL MARKETS 0.03% of their portfolio PARIS, I0 558,097558.1k $39.0m $39.0m 0.03% Added +97.3k +97,305
88 Hardman Johnston Global Advisors LLC 1.71% of their portfolio Stamford, CT 552,657552.7k $38.6m $38.6m 1.71% Reduced -9.2k -9,228
89 Schonfeld Strategic Advisors LLC 0.29% of their portfolio NEW YORK, NY 547,580547.6k $38.3m $38.3m 0.29% Added +524.2k +524,220
90 Cerity Partners LLC 0.07% of their portfolio NEW YORK, NY 535,866535.9k $37.4m $37.4m 0.07% Added +72.6k +72,605
91 THORNBURG INVESTMENT MANAGEMENT INC 0.48% of their portfolio SANTA FE, NM 535,650535.6k $37.4m $37.4m 0.48% Added +18.6k +18,563
92 MACKENZIE FINANCIAL CORP 0.05% of their portfolio TORONTO ONTARIO, A6 521,502521.5k $36.4m $36.4m 0.05% Added +118.7k +118,653
93 Alyeska Investment Group, L.P. 0.13% of their portfolio CHICAGO, IL 513,311513.3k $35.9m $35.9m 0.13% Reduced -391.7k -391,689
94 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 505,055505.1k $35.3m $35.3m 0.00% Added +14.0k +14,025
95 VAUGHAN DAVID INVESTMENTS LLC/IL 0.79% of their portfolio PEORIA, IL 504,915504.9k $35.3m $35.3m 0.79% Added +12.2k +12,182
96 Nuveen, LLC 0.01% of their portfolio CHARLOTTE, NC 499,272499.3k $34.9m $34.9m 0.01% Reduced -45.5k -45,511
97 Cubist Systematic Strategies, LLC 0.37% of their portfolio STAMFORD, CT 484,078484.1k $33.8m $33.8m 0.37% Added +249.4k +249,364
98 Crestwood Advisors Group, LLC 0.60% of their portfolio BOSTON, MA 475,183475.2k $33.2m $33.2m 0.60% Added +42.8k +42,774
99 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.06% of their portfolio CAUSEWAY BAY, K3 472,062472.1k $33.0m $33.0m 0.06% Reduced -17.0k -17,021
100 AXA S.A. 0.09% of their portfolio PARIS, I0 471,184471.2k $32.9m $32.9m 0.09% Added +7.0k +6,995