Vault-13

ASCENDIS PHARMA A/S

SPONSORED ADR · CUSIP 04351P101 · ISIN US04351P1012

11 institutional holders -255 vs Q1 2026
1,056,6561.1m shares reported held*
$281.8mreported value*
2 new 5 added 1 reduced 254 sold out net sold ≈ $14.3bn (-53.7m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $266.67. Options: 1 managers hold calls ($9.4m notional), 0 hold puts (—).

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

0200400Q3 22: 183Q4 22: 187Q1 23: 165Q2 23: 159Q3 23: 161Q4 23: 186Q1 24: 190Q2 24: 204Q3 24: 221Q4 24: 216Q1 25: 246Q2 25: 249Q3 25: 281Q4 25: 303Q1 26: 266Q2 26: 1111Q3 22Q3 23Q3 24Q3 25Q2 26
Numbers
QuarterHolders
Q3 2022183
Q4 2022187
Q1 2023165
Q2 2023159
Q3 2023161
Q4 2023186
Q1 2024190
Q2 2024204
Q3 2024221
Q4 2024216
Q1 2025246
Q2 2025249
Q3 2025281
Q4 2025303
Q1 2026266
Q2 202611

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
4000400Q3 24: 117 bought or addedQ3 24: 94 cut or sold outQ4 24: 113 bought or addedQ4 24: 106 cut or sold outQ4 24Q1 25: 129 bought or addedQ1 25: 110 cut or sold outQ2 25: 121 bought or addedQ2 25: 129 cut or sold outQ2 25Q3 25: 155 bought or addedQ3 25: 114 cut or sold outQ4 25: 172 bought or addedQ4 25: 130 cut or sold outQ4 25Q1 26: 139 bought or addedQ1 26: 167 cut or sold outQ2 26: 7 bought or addedQ2 26: 255 cut or sold outQ2 26
Numbers
QuarterBought or addedCut or sold out
Q3 202411794
Q4 2024113106
Q1 2025129110
Q2 2025121129
Q3 2025155114
Q4 2025172130
Q1 2026139167
Q2 20267255

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$100m$200m$300m$400mQ3 25 calls: $139.1mQ3 25 puts: $49.3mQ3 25P/C 0.35Q4 25 calls: $199.7mQ4 25 puts: $62.9mQ4 25P/C 0.32Q1 26 calls: $332.9mQ1 26 puts: $58.0mQ1 26P/C 0.17Q2 26 calls: $9.4mQ2 26 puts: $0Q2 26P/C 0.00
Numbers
QuarterCallsPutsP/C
Q3 2025$139.1m$49.3m0.35
Q4 2025$199.7m$62.9m0.32
Q1 2026$332.9m$58.0m0.17
Q2 2026$9.4m$00.00

Biggest buyers

STATE STREET CORP Added +426,635+426.6k
NEUBERGER BERMAN GROUP LLC New +142,705+142.7k
Frazier Life Sciences Management, L.P. Added +91,822+91.8k
Quadrature Capital Ltd New +40,845+40.8k
DEARBORN PARTNERS LLC Added +1,300+1.3k
E Fund Management (Hong Kong) Co., Ltd. Added +24+24
IFP Advisors, Inc Added +2+2

Biggest sellers

RA CAPITAL MANAGEMENT, L.P. Sold out -10,281,496-10.3m
Avoro Capital Advisors LLC Sold out -5,062,500-5.1m
WESTFIELD CAPITAL MANAGEMENT CO LP Sold out -4,813,440-4.8m
FMR LLC Sold out -3,876,601-3.9m
Artisan Partners Limited Partnership Sold out -3,230,188-3.2m
FRANKLIN RESOURCES INC Sold out -2,051,948-2.1m
Capital International Investors Sold out -1,958,843-2.0m
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ Sold out -1,860,669-1.9m
WELLINGTON MANAGEMENT GROUP LLP Sold out -1,757,633-1.8m
PERCEPTIVE ADVISORS LLC Sold out -1,531,421-1.5m

Biggest calls

Q Global Advisors, LLC Unchanged $9.4m41.0k shares

Biggest puts

None

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
T. Rowe Price Investment Management, Inc. 13G · institution +0.6 pts · filed 2026-05-07 10.5% +0.6 pts 6.5m 2026-05-07
WESTFIELD CAPITAL MANAGEMENT CO LP 13G · institution -0.7 pts · filed 2026-02-11 8.5% -0.7 pts 5.2m 2026-02-11
FMR LLC 13G · institution filed 2025-05-12 8.0% 4.6m 2025-05-12
JANUS HENDERSON GROUP PLC 13G · institution -1.8 pts · filed 2026-05-15 6.0% -1.8 pts 3.7m 2026-05-15
Artisan Partners Limited Partnership 13G · institution filed 2026-02-03 5.2% 3.2m 2026-02-03

Fell to 5% or below in the last year: Capital International Investors (3.2%, 2026-05-14)

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 513,969514.0k $137.1m $137.1m 0.00% Added +426.6k +426,635
2 Frazier Life Sciences Management, L.P. 1.31% of their portfolio PALO ALTO, CA 225,155225.2k $60.1m $60.1m 1.31% Added +91.8k +91,822
3 NEUBERGER BERMAN GROUP LLC 0.03% of their portfolio NEW YORK, NY 142,705142.7k $38.1m $38.1m 0.03% New
4 ODDO BHF ASSET MANAGEMENT SAS 1.59% of their portfolio PARIS, I0 128,657128.7k $34.3m $34.3m 1.59% Unchanged
5 Quadrature Capital Ltd 0.09% of their portfolio LONDON, X0 40,84540.8k $10.9m $10.9m 0.09% New
6 FERGUSON WELLMAN CAPITAL MANAGEMENT, INC 0.01% of their portfolio PORTLAND, OR 2,6002.6k $693.5k $693.5k 0.01% Unchanged
7 DEARBORN PARTNERS LLC 0.02% of their portfolio CHICAGO, IL 2,6002.6k $644.1k $644.1k 0.02% Added +1.3k +1,300
8 E Fund Management (Hong Kong) Co., Ltd. 0.01% of their portfolio CENTRAL, K3 8484 $22.4k $22.4k 0.01% Added +24 +24
9 Ninepoint Partners LP 0.00% of their portfolio TORONTO, A6 2626 $6.9k $6.9k 0.00% Reduced -5.4k -5,400
10 IFP Advisors, Inc 0.00% of their portfolio TAMPA, FL 1414 $3.4k $3.4k 0.00% Added +2 +2
11 HUNTINGTON NATIONAL BANK 0.00% of their portfolio COLUMBUS, OH 11 $244 $244 0.00% Unchanged