ARGENX SE ARGX
SPONSORED ADR · ADR · CUSIP 04016X101 · ISIN US04016X1019
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($775.7k this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $380.45. Options: 28 managers hold calls ($325.1m notional), 25 hold puts ($223.3m).
Trends to Q4 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 255 |
| Q4 2022 | 271 |
| Q1 2023 | 273 |
| Q2 2023 | 291 |
| Q3 2023 | 342 |
| Q4 2023 | 347 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 114 | 139 |
| Q1 2023 | 123 | 139 |
| Q2 2023 | 151 | 117 |
| Q3 2023 | 208 | 117 |
| Q4 2023 | 193 | 156 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2023 | $208.4m | $162.6m | 0.78 |
| Q2 2023 | $245.0m | $410.6m | 1.68 |
| Q3 2023 | $364.6m | $125.5m | 0.34 |
| Q4 2023 | $325.1m | $223.3m | 0.69 |
Biggest buyers
| MORGAN STANLEY | Added | +750.9k |
| Capital World Investors | Added | +530.2k |
| Artisan Partners Limited Partnership | Added | +346.2k |
| JANUS HENDERSON GROUP PLC | Added | +305.6k |
| EcoR1 Capital, LLC | New | +301.0k |
| Deep Track Capital, LP | New | +300.0k |
| Avoro Capital Advisors LLC | Added | +234.6k |
| T. Rowe Price Investment Management, Inc. | Added | +215.8k |
| DEUTSCHE BANK AG\ | Added | +182.4k |
| Paradigm Biocapital Advisors LP | Added | +161.1k |
Biggest sellers
| JENNISON ASSOCIATES LLC | Reduced | -1.2m |
| FMR LLC | Reduced | -1.2m |
| LORD, ABBETT & CO. LLC | Sold out | -632.8k |
| CITADEL ADVISORS LLC | Reduced | -247.8k |
| 1832 Asset Management L.P. | Sold out | -214.8k |
| MARSHALL WACE, LLP | Reduced | -182.9k |
| PERCEPTIVE ADVISORS LLC | Sold out | -150.6k |
| Point72 Asset Management, L.P. | Reduced | -132.4k |
| RENAISSANCE TECHNOLOGIES LLC | Sold out | -104.7k |
| Nicholas Investment Partners, LP | Reduced | -77.6k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $74.8m196.7k shares |
| MILLENNIUM MANAGEMENT LLC | New | $56.5m148.4k shares |
| CITADEL ADVISORS LLC | Added | $32.2m84.6k shares |
| Ikarian Capital, LLC | New | $29.7m78.1k shares |
| JPMORGAN CHASE & CO | Reduced | $18.7m49.2k shares |
| SIMPLEX TRADING, LLC | Added | $17.0m44.6k shares |
| TIG Advisors, LLC | New | $14.3m37.6k shares |
| GROUP ONE TRADING LLC | Added | $12.3m32.4k shares |
| CITIGROUP INC | Added | $11.4m30.0k shares |
| STEMPOINT CAPITAL LP | First filing | $10.1m26.5k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $40.7m106.9k shares |
| JPMORGAN CHASE & CO | Added | $30.6m80.4k shares |
| Ikarian Capital, LLC | New | $29.7m78.1k shares |
| CITADEL ADVISORS LLC | Added | $26.1m68.6k shares |
| D. E. Shaw & Co., Inc. | Added | $12.5m32.9k shares |
| Melqart Asset Management (UK) Ltd | New | $12.4m32.5k shares |
| SIMPLEX TRADING, LLC | Added | $9.4m24.6k shares |
| SAL Trading, LLC | Added | $8.2m21.5k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | $8.0m20.9k shares |
| BARCLAYS PLC | New | $7.6m20.0k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
No one currently above 5% in the filings since 19 Dec 2024.
Fell to 5% or below in the last year: PRICE T ROWE ASSOCIATES INC /MD/ (4.3%, 2026-08-14)
Insider purchases and sales in Q4 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q4 2023.
Holders, Q4 2023
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.11% of their portfolio | 3.8m $1.5bn | Reduced -1.2m |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.19% of their portfolio | 3.7m $1.4bn | Added +14.3k |
| Artisan Partners Limited Partnership 1.90% of their portfolio | 3.2m $1.2bn | Added +346.2k |
| Capital World Investors 0.13% of their portfolio | 2.0m $746.1m | Added +530.2k |
| JANUS HENDERSON GROUP PLC 0.40% of their portfolio | 1.8m $675.9m | Added +305.6k |
| MORGAN STANLEY 0.02% of their portfolio | 1.3m $496.8m | Added +750.9k |
| Avoro Capital Advisors LLC 6.49% of their portfolio | 1.2m $469.7m | Added +234.6k |
| T. Rowe Price Investment Management, Inc. 0.29% of their portfolio | 1.2m $449.7m | Added +215.8k |
| BlackRock Inc. 0.01% of their portfolio | 992.0k $377.4m | Reduced -161 |
| Bellevue Group AG 5.06% of their portfolio | 869.2k $330.7m | Reduced -42.3k |
| RTW INVESTMENTS, LP 3.96% of their portfolio | 667.2k $253.8m | Added +160.0k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.07% of their portfolio | 591.7k $225.1m | Added +10.1k |
| Holocene Advisors, LP 0.79% of their portfolio | 528.7k $201.1m | Added +156.5k |
| Clearbridge Investments, LLC 0.14% of their portfolio | 436.8k $166.2m | Added +92.4k |
| Invesco Ltd. 0.04% of their portfolio | 436.2k $166.0m | Added +5.4k |
| Paradigm Biocapital Advisors LP 7.53% of their portfolio | 422.6k $160.8m | Added +161.1k |
| FEDERATED HERMES, INC. 0.34% of their portfolio | 356.5k $135.6m | Added +24.4k |
| MILLENNIUM MANAGEMENT LLC 0.12% of their portfolio | 345.4k $131.4m | Added +67.1k |
| SEI INVESTMENTS CO 0.20% of their portfolio | 332.0k $126.3m | Added +45.7k |
| ARMISTICE CAPITAL, LLC 3.21% of their portfolio | 318.0k $121.0m | Added +118.0k |
| Pictet Asset Management Holding SA 0.13% of their portfolio | 313.2k $119.2m | Reduced -76.1k |
| EcoR1 Capital, LLC 2.97% of their portfolio | 301.0k $114.5m | New |
| Deep Track Capital, LP 4.00% of their portfolio | 300.0k $114.1m | New |
| BAMCO INC /NY/ 0.29% of their portfolio | 287.4k $109.3m | Reduced -612 |
| WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio | 279.2k $106.2m | Added +58.0k |
| JENNISON ASSOCIATES LLC 0.08% of their portfolio | 268.2k $102.0m | Reduced -1.2m |
| GOLDMAN SACHS GROUP INC 0.02% of their portfolio | 252.4k $96.0m | Added +98.7k |
| EVENTIDE ASSET MANAGEMENT, LLC 1.53% of their portfolio | 245.8k $93.5m | Reduced -75.6k |
| Alyeska Investment Group, L.P. 0.60% of their portfolio | 234.8k $89.3m | Added +119.7k |
| Rock Springs Capital Management LP 2.15% of their portfolio | 229.2k $87.2m | Reduced -29.8k |
| TD Asset Management Inc 0.07% of their portfolio | 193.9k $73.8m | Added +18.5k |
| DEUTSCHE BANK AG\ 0.04% of their portfolio | 189.4k $72.1m | Added +182.4k |
| CITADEL ADVISORS LLC 0.07% of their portfolio | 188.4k $71.7m | Reduced -247.8k |
| FRANKLIN RESOURCES INC 0.03% of their portfolio | 174.2k $66.3m | Reduced -8.4k |
| D. E. Shaw & Co., Inc. 0.09% of their portfolio | 170.7k $65.0m | Reduced -40.5k |
| Balyasny Asset Management L.P. 0.17% of their portfolio | 165.4k $62.9m | Added +73.2k |
| Fiera Capital Corp 0.19% of their portfolio | 163.4k $62.2m | Added +1.5k |
| Boxer Capital, LLC 3.03% of their portfolio | 160.0k $60.9m | Added +75.0k |
| AMERICAN CENTURY COMPANIES INC 0.04% of their portfolio | 155.7k $59.2m | Reduced -23.2k |
| BRAIDWELL LP 2.14% of their portfolio | 153.2k $58.3m | New |
| BAKER BROS. ADVISORS LP 0.65% of their portfolio | 151.2k $57.5m | Unchanged |
| NEW YORK STATE COMMON RETIREMENT FUND 0.08% of their portfolio | 146.2k $55.6m | Added +19.0k |
| Logos Global Management LP 6.13% of their portfolio | 145.0k $55.2m | New |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 138.7k $52.7m | Reduced -6.6k |
| Assenagon Asset Management S.A. 0.15% of their portfolio | 128.5k $48.9m | Added +89.2k |
| MARSHALL WACE, LLP 0.09% of their portfolio | 125.7k $47.8m | Reduced -182.9k |
| Point72 Asset Management, L.P. 0.14% of their portfolio | 118.1k $44.9m | Reduced -132.4k |
| Artal Group S.A. 1.51% of their portfolio | 116.4k $44.3m | New |
| Fairmount Funds Management LLC 4.54% of their portfolio | 112.9k $43.0m | Added +29.2k |
| TimesSquare Capital Management, LLC 0.63% of their portfolio | 112.7k $42.9m | Added +11.0k |
| BNP PARIBAS FINANCIAL MARKETS 0.08% of their portfolio | 111.0k $42.2m | Added +29.9k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.09% of their portfolio | 109.0k $41.4m | Added +3.0k |
| Hudson Bay Capital Management LP 0.33% of their portfolio | 99.0k $37.7m | Reduced -37.0k |
| PFM Health Sciences, LP 1.98% of their portfolio | 86.8k $33.0m | Reduced -17.9k |
| Allspring Global Investments Holdings, LLC 0.05% of their portfolio | 86.2k $32.8m | Added +15.4k |
| AXA S.A. 0.05% of their portfolio | 86.1k $32.8m | Added +41.8k |
| Eversept Partners, LP 3.20% of their portfolio | 85.8k $32.7m | Added +81.3k |
| ORBIMED ADVISORS LLC 0.64% of their portfolio | 84.6k $32.2m | Added +52.0k |
| Eagle Health Investments LP 6.54% of their portfolio | 84.6k $32.2m | Added +20.2k |
| First Turn Management, LLC 4.56% of their portfolio | 83.4k $31.7m | First filing |
| FIRST TRUST ADVISORS LP 0.03% of their portfolio | 79.8k $30.3m | Reduced -3.2k |
| Legal & General Group Plc 0.01% of their portfolio | 78.3k $29.8m | Added +13.9k |
| Aberdeen Group plc 0.06% of their portfolio | 73.5k $28.0m | New |
| Ikarian Capital, LLC 7.26% of their portfolio | 70.0k $26.5m | New |
| Checkpoint Capital L.P. 18.58% of their portfolio | 70.0k $26.6m | First filing |
| Thrivent Financial for Lutherans 0.05% of their portfolio | 61.9k $23.5m | Reduced -7.2k |
| MONTANOVA CAPITAL, LLC 0.93% of their portfolio | 53.7k $20.4m | Added +50.9k |
| Saturn V Capital Management LP 7.45% of their portfolio | 51.2k $19.5m | Added +41.1k |
| ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio | 47.9k $18.2m | Added +4.0k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.01% of their portfolio | 47.6k $18.1m | Added +4.0k |
| ROYAL LONDON ASSET MANAGEMENT LTD 0.05% of their portfolio | 46.3k $17.6m | Reduced -1.4k |
| VAN ECK ASSOCIATES CORP 0.03% of their portfolio | 46.1k $17.6m | Added +5.0k |
| Sofinnova Investments, Inc. 0.95% of their portfolio | 44.7k $17.0m | Reduced -33.5k |
| Driehaus Capital Management LLC 0.20% of their portfolio | 44.7k $17.0m | Added +8.3k |
| PGGM Investments 0.26% of their portfolio | 44.6k $17.0m | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 42.3k $16.1m | Reduced -13.8k |
| BARCLAYS PLC 0.01% of their portfolio | 41.4k $15.8m | Added +2.5k |
| Walleye Capital LLC 0.21% of their portfolio | 39.8k $15.1m | Added +39.3k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 38.5k $14.6m | Added +7.5k |
| Polar Asset Management Partners Inc. 0.37% of their portfolio | 35.9k $13.7m | Added +18.8k |
| Ally Bridge Group (NY) LLC 7.93% of their portfolio | 35.0k $13.3m | New |
| Artia Global Partners LP 5.15% of their portfolio | 34.2k $13.0m | Reduced -15.0k |
| RAYMOND JAMES & ASSOCIATES 0.01% of their portfolio | 33.3k $12.7m | Reduced -459 |
| QVT Financial LP 0.75% of their portfolio | 32.5k $12.4m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 31.3k $11.9m | Reduced -8.6k |
| Avidity Partners Management LP 0.45% of their portfolio | 31.0k $11.8m | Reduced -49.6k |
| AWM Investment Company, Inc. 1.50% of their portfolio | 30.0k $11.4m | Unchanged |
| Russell Investments Group, Ltd. 0.02% of their portfolio | 29.9k $11.4m | Added +3.5k |
| Altitude Crest Partners Inc. 7.51% of their portfolio | 29.5k $11.2m | First filing |
| Verition Fund Management LLC 0.11% of their portfolio | 28.1k $10.7m | Reduced -15.0k |
| Decheng Capital LLC 2.92% of their portfolio | 27.4k $10.4m | First filing |
| BANK OF MONTREAL /CAN/ 0.00% of their portfolio | 27.0k $10.5m | Reduced -5.2k |
| Atika Capital Management LLC 1.44% of their portfolio | 26.7k $10.2m | Added +2.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 25.9k $9.9m | Added +1.6k |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 25.9k $9.9m | Added +14.3k |
| Handelsbanken Fonder AB 0.05% of their portfolio | 25.9k $9.8m | Reduced -1.6k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 25.0k $9.5m | Added +811 |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 25.0k $9.5m | Added +1.4k |
| MOORE CAPITAL MANAGEMENT, LP 0.23% of their portfolio | 25.0k $9.5m | Added +9.0k |
| Tri Locum Partners LP 4.52% of their portfolio | 24.2k $9.2m | Added +9.8k |