ARGENX SE ARGX
SPONSORED ADR · ADR · CUSIP 04016X101 · ISIN US04016X1019
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.1m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $491.65. Options: 20 managers hold calls ($364.6m notional), 17 hold puts ($125.5m).
Trends to Q3 2023
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 255 |
| Q4 2022 | 271 |
| Q1 2023 | 273 |
| Q2 2023 | 291 |
| Q3 2023 | 342 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 114 | 139 |
| Q1 2023 | 123 | 139 |
| Q2 2023 | 151 | 117 |
| Q3 2023 | 208 | 117 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2022 | $108.3m | $72.4m | 0.67 |
| Q1 2023 | $208.4m | $162.6m | 0.78 |
| Q2 2023 | $245.0m | $410.6m | 1.68 |
| Q3 2023 | $364.6m | $125.5m | 0.34 |
Biggest buyers
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | Added | +449.2k |
| BlackRock Inc. | Added | +401.3k |
| JENNISON ASSOCIATES LLC | Added | +368.4k |
| Invesco Ltd. | Added | +340.5k |
| LORD, ABBETT & CO. LLC | Added | +274.0k |
| Point72 Asset Management, L.P. | New | +250.5k |
| Capital World Investors | Added | +248.6k |
| Clearbridge Investments, LLC | Added | +174.9k |
| Paradigm Biocapital Advisors LP | Added | +119.2k |
| MARSHALL WACE, LLP | Added | +116.4k |
Biggest sellers
| JANUS HENDERSON GROUP PLC | Reduced | -312.3k |
| Avoro Capital Advisors LLC | Reduced | -263.5k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Reduced | -237.9k |
| Darwin Global Management, Ltd. | Reduced | -227.7k |
| Artisan Partners Limited Partnership | Reduced | -210.1k |
| DEUTSCHE BANK AG\ | Reduced | -147.2k |
| BAKER BROS. ADVISORS LP | Reduced | -128.9k |
| Avidity Partners Management LP | Reduced | -103.7k |
| T. Rowe Price Investment Management, Inc. | Reduced | -98.5k |
| Rock Springs Capital Management LP | Reduced | -91.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $72.9m148.2k shares |
| ARMISTICE CAPITAL, LLC | New | $68.8m140.0k shares |
| Caption Management, LLC | Added | $61.2m124.5k shares |
| JPMORGAN CHASE & CO | Added | $47.3m96.2k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | $25.2m51.2k shares |
| CITADEL ADVISORS LLC | Reduced | $19.6m39.8k shares |
| SAL Trading, LLC | Added | $17.7m36.1k shares |
| CITIGROUP INC | New | $13.6m27.6k shares |
| GROUP ONE TRADING LLC | Reduced | $11.9m24.3k shares |
| Optiver Holding B.V. | Unchanged | $10.1m20.5k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $59.1m120.3k shares |
| CITADEL ADVISORS LLC | Unchanged | $17.0m34.6k shares |
| JANE STREET GROUP, LLC | Reduced | $11.6m23.5k shares |
| D. E. Shaw & Co., Inc. | New | $9.1m18.5k shares |
| GROUP ONE TRADING LLC | Reduced | $7.6m15.5k shares |
| SIMPLEX TRADING, LLC | Added | $6.2m12.6k shares |
| CITIGROUP INC | New | $4.4m9.0k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | $3.3m6.7k shares |
| Optiver Holding B.V. | Unchanged | $2.9m5.8k shares |
| SAL Trading, LLC | New | $1.8m3.7k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
No one currently above 5% in the filings since 19 Dec 2024.
Fell to 5% or below in the last year: PRICE T ROWE ASSOCIATES INC /MD/ (4.3%, 2026-08-14)
Insider purchases and sales in Q3 2023
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
None reported in Q3 2023.
Holders, Q3 2023
| Manager | Shares | Change |
|---|---|---|
| FMR LLC 0.21% of their portfolio | 5.0m $2.4bn | Reduced -90.8k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.26% of their portfolio | 3.7m $1.8bn | Reduced -237.9k |
| Artisan Partners Limited Partnership 2.36% of their portfolio | 2.8m $1.4bn | Reduced -210.1k |
| JENNISON ASSOCIATES LLC 0.63% of their portfolio | 1.5m $743.2m | Added +368.4k |
| JANUS HENDERSON GROUP PLC 0.47% of their portfolio | 1.5m $723.3m | Reduced -312.3k |
| Capital World Investors 0.14% of their portfolio | 1.4m $703.5m | Added +248.6k |
| Avoro Capital Advisors LLC 7.67% of their portfolio | 1.0m $491.6m | Reduced -263.5k |
| BlackRock Inc. 0.01% of their portfolio | 992.2k $487.8m | Added +401.3k |
| T. Rowe Price Investment Management, Inc. 0.34% of their portfolio | 966.4k $475.1m | Reduced -98.5k |
| Bellevue Group AG 7.22% of their portfolio | 911.5k $448.1m | Reduced -11.8k |
| LORD, ABBETT & CO. LLC 0.58% of their portfolio | 632.8k $311.1m | Added +274.0k |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.10% of their portfolio | 581.6k $285.9m | Added +449.2k |
| MORGAN STANLEY 0.03% of their portfolio | 554.9k $272.8m | Reduced -1.5k |
| RTW INVESTMENTS, LP 5.26% of their portfolio | 507.2k $249.4m | Added +25.0k |
| CITADEL ADVISORS LLC 0.23% of their portfolio | 436.1k $214.4m | Added +75.5k |
| Invesco Ltd. 0.06% of their portfolio | 430.8k $211.8m | Added +340.5k |
| Pictet Asset Management Holding SA 0.24% of their portfolio | 389.3k $191.4m | First filing |
| Holocene Advisors, LP 0.82% of their portfolio | 372.2k $183.0m | Added +13.9k |
| Clearbridge Investments, LLC 0.16% of their portfolio | 344.4k $169.3m | Added +174.9k |
| FEDERATED HERMES, INC. 0.44% of their portfolio | 332.1k $163.3m | Reduced -2.1k |
| EVENTIDE ASSET MANAGEMENT, LLC 2.84% of their portfolio | 321.4k $158.0m | Reduced -7.7k |
| MARSHALL WACE, LLP 0.33% of their portfolio | 308.5k $151.7m | Added +116.4k |
| BAMCO INC /NY/ 0.41% of their portfolio | 288.0k $141.6m | Added +37.7k |
| SEI INVESTMENTS CO 0.25% of their portfolio | 286.3k $140.8m | Added +26.2k |
| MILLENNIUM MANAGEMENT LLC 0.14% of their portfolio | 278.3k $136.8m | Added +72.4k |
| Paradigm Biocapital Advisors LP 8.77% of their portfolio | 261.4k $128.5m | Added +119.2k |
| Rock Springs Capital Management LP 3.41% of their portfolio | 259.0k $127.3m | Reduced -91.0k |
| Point72 Asset Management, L.P. 0.42% of their portfolio | 250.5k $123.2m | New |
| WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio | 221.2k $108.8m | Reduced -12.8k |
| 1832 Asset Management L.P. 0.22% of their portfolio | 214.8k $105.6m | Reduced -5.4k |
| D. E. Shaw & Co., Inc. 0.17% of their portfolio | 211.3k $103.9m | Added +31.0k |
| ARMISTICE CAPITAL, LLC 2.92% of their portfolio | 200.0k $98.3m | Unchanged |
| FRANKLIN RESOURCES INC 0.05% of their portfolio | 182.7k $89.8m | Reduced -63.6k |
| AMERICAN CENTURY COMPANIES INC 0.07% of their portfolio | 178.8k $87.9m | Reduced -6.3k |
| TD Asset Management Inc 0.10% of their portfolio | 175.4k $86.2m | Added +51.8k |
| Fiera Capital Corp 0.25% of their portfolio | 162.0k $79.6m | Added +3.7k |
| GOLDMAN SACHS GROUP INC 0.02% of their portfolio | 153.6k $75.5m | Added +15.9k |
| BAKER BROS. ADVISORS LP 0.43% of their portfolio | 151.2k $74.3m | Reduced -128.9k |
| PERCEPTIVE ADVISORS LLC 2.49% of their portfolio | 150.6k $74.0m | Added +81.6k |
| BANK OF AMERICA CORP /DE/ 0.01% of their portfolio | 145.2k $71.4m | Reduced -58.6k |
| Hudson Bay Capital Management LP 0.32% of their portfolio | 136.0k $66.9m | Added +99.1k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.09% of their portfolio | 127.1k $62.5m | Reduced -7.7k |
| Alyeska Investment Group, L.P. 0.39% of their portfolio | 115.1k $56.6m | New |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.12% of their portfolio | 106.0k $52.1m | Reduced -46.8k |
| PFM Health Sciences, LP 2.46% of their portfolio | 104.7k $51.5m | Unchanged |
| RENAISSANCE TECHNOLOGIES LLC 0.09% of their portfolio | 104.7k $51.5m | Reduced -9.3k |
| TimesSquare Capital Management, LLC 0.78% of their portfolio | 101.8k $50.0m | Added +11.1k |
| Nicholas Investment Partners, LP 3.44% of their portfolio | 93.6k $46.0m | Reduced -1.8k |
| Balyasny Asset Management L.P. 0.13% of their portfolio | 92.2k $45.3m | Reduced -67.3k |
| Boxer Capital, LLC 2.22% of their portfolio | 85.0k $41.8m | Added +10.0k |
| Fairmount Funds Management LLC 4.95% of their portfolio | 83.7k $41.2m | Added +10.2k |
| FIRST TRUST ADVISORS LP 0.05% of their portfolio | 83.0k $40.8m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.09% of their portfolio | 81.1k $39.9m | Added +19.6k |
| Avidity Partners Management LP 1.60% of their portfolio | 80.6k $39.6m | Reduced -103.7k |
| Sofinnova Investments, Inc. 2.70% of their portfolio | 78.2k $38.4m | Added +38.3k |
| Public Sector Pension Investment Board 0.28% of their portfolio | 77.4k $38.0m | Unchanged |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.18% of their portfolio | 73.1k $36.0m | New |
| Qube Research & Technologies Ltd 0.11% of their portfolio | 72.9k $35.9m | Added +37.2k |
| Allspring Global Investments Holdings, LLC 0.06% of their portfolio | 70.8k $34.8m | Reduced -20.2k |
| Integral Health Asset Management, LLC 4.88% of their portfolio | 70.0k $34.4m | Added +30.0k |
| Thrivent Financial for Lutherans 0.08% of their portfolio | 69.1k $34.0m | Added +866 |
| Eagle Health Investments LP 6.98% of their portfolio | 64.4k $31.7m | Unchanged |
| Legal & General Group Plc 0.01% of their portfolio | 64.4k $31.7m | Added +3.0k |
| WELLS FARGO & COMPANY/MN 0.01% of their portfolio | 56.1k $27.6m | Added +28.9k |
| Artia Global Partners LP 10.06% of their portfolio | 49.2k $24.2m | Added +2.8k |
| ROYAL LONDON ASSET MANAGEMENT LTD 0.08% of their portfolio | 47.7k $23.5m | New |
| Darwin Global Management, Ltd. 7.89% of their portfolio | 45.6k $22.4m | Reduced -227.7k |
| PGGM Investments 0.38% of their portfolio | 44.6k $21.9m | Unchanged |
| AXA S.A. 0.08% of their portfolio | 44.3k $21.8m | Added +26.6k |
| ENVESTNET ASSET MANAGEMENT INC 0.01% of their portfolio | 43.9k $21.6m | Added +25.9k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.01% of their portfolio | 43.6k $21.4m | Added +104 |
| Verition Fund Management LLC 0.28% of their portfolio | 43.1k $21.2m | Added +36.6k |
| VAN ECK ASSOCIATES CORP 0.04% of their portfolio | 41.2k $20.2m | Reduced -13.4k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 39.9k $19.6m | Added +11.6k |
| Assenagon Asset Management S.A. 0.07% of their portfolio | 39.3k $19.3m | Added +11.3k |
| BARCLAYS PLC 0.01% of their portfolio | 39.0k $19.1m | Added +31.6k |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 36.5k $18.0m | New |
| Driehaus Capital Management LLC 0.23% of their portfolio | 36.3k $17.9m | Reduced -7 |
| RAYMOND JAMES & ASSOCIATES 0.01% of their portfolio | 33.8k $16.6m | Added +19.2k |
| ORBIMED ADVISORS LLC 0.34% of their portfolio | 32.6k $16.0m | Unchanged |
| QVT Financial LP 0.95% of their portfolio | 32.5k $16.0m | Unchanged |
| BANK OF MONTREAL /CAN/ 0.01% of their portfolio | 32.1k $17.0m | Reduced -14.7k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.01% of their portfolio | 30.9k $15.2m | Reduced -3.5k |
| AWM Investment Company, Inc. 2.18% of their portfolio | 30.0k $14.7m | Reduced -15.0k |
| Caption Management, LLC 1.88% of their portfolio | 29.6k $14.6m | Reduced -4.5k |
| NATIXIS ADVISORS, LLC 0.04% of their portfolio | 28.4k $14.0m | New |
| Handelsbanken Fonder AB 0.08% of their portfolio | 27.5k $13.5m | Added +1.4k |
| Decheng Capital Management III (Cayman), LLC 4.50% of their portfolio | 27.4k $13.5m | Unchanged |
| Russell Investments Group, Ltd. 0.03% of their portfolio | 26.4k $13.0m | Added +13.2k |
| Atika Capital Management LLC 1.73% of their portfolio | 24.7k $12.1m | Unchanged |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 24.4k $12.0m | Added +9 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 24.2k $11.9m | Added +1.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 23.6k $11.6m | Reduced -58.9k |
| Ensign Peak Advisors, Inc 0.02% of their portfolio | 23.6k $11.6m | Reduced -154 |
| CITIGROUP INC 0.02% of their portfolio | 23.3k $11.4m | Added +20.4k |
| DCF Advisers, LLC 7.55% of their portfolio | 22.0k $10.8m | Reduced -3.7k |
| PINEBRIDGE INVESTMENTS, L.P. 0.11% of their portfolio | 21.0k $10.3m | Reduced -259 |
| Schonfeld Strategic Advisors LLC 0.09% of their portfolio | 19.2k $9.5m | Added +15.5k |
| CLOUGH CAPITAL PARTNERS L P 0.93% of their portfolio | 17.6k $8.6m | New |
| Polar Asset Management Partners Inc. 0.20% of their portfolio | 17.1k $8.4m | Added +10.9k |