ARCUS BIOSCIENCES INC RCUS
COM · Common Stock · CUSIP 03969F109
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersHayward, CA
- Founded2015
- Websitearcusbio.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($4.3m this quarter). Holder counts are more reliable. Shares outstanding: 91.5m as of 2024-10-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $14.89. Options: 8 managers hold calls ($5.1m notional), 6 hold puts ($2.1m).
Trends to Q4 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 185 |
| Q4 2022 | 201 |
| Q1 2023 | 182 |
| Q2 2023 | 183 |
| Q3 2023 | 188 |
| Q4 2023 | 186 |
| Q1 2024 | 173 |
| Q2 2024 | 194 |
| Q3 2024 | 188 |
| Q4 2024 | 187 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2023 | 97 | 99 |
| Q2 2023 | 81 | 91 |
| Q3 2023 | 83 | 96 |
| Q4 2023 | 83 | 92 |
| Q1 2024 | 79 | 90 |
| Q2 2024 | 100 | 84 |
| Q3 2024 | 88 | 95 |
| Q4 2024 | 75 | 91 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q1 2024 | $5.4m | $3.2m | 0.60 |
| Q2 2024 | $3.6m | $2.3m | 0.65 |
| Q3 2024 | $3.8m | $2.2m | 0.58 |
| Q4 2024 | $5.1m | $2.1m | 0.41 |
Biggest buyers
| BRAIDWELL LP | New | +802.1k |
| MILLENNIUM MANAGEMENT LLC | Added | +679.3k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | Added | +590.7k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | New | +465.3k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | New | +443.0k |
| READYSTATE ASSET MANAGEMENT LP | New | +351.4k |
| Parkman Healthcare Partners LLC | Added | +248.0k |
| AMERIPRISE FINANCIAL INC | Added | +228.3k |
| Trexquant Investment LP | Added | +212.6k |
| DIMENSIONAL FUND ADVISORS LP | Added | +178.4k |
Biggest sellers
| Boxer Capital, LLC | Sold out | -1.6m |
| ALLIANCEBERNSTEIN L.P. | Reduced | -1.2m |
| Schonfeld Strategic Advisors LLC | Reduced | -538.8k |
| Point72 Asset Management, L.P. | Reduced | -440.8k |
| FMR LLC | Reduced | -415.0k |
| Ikarian Capital, LLC | Reduced | -365.6k |
| GOLDMAN SACHS GROUP INC | Reduced | -259.9k |
| Walleye Capital LLC | Sold out | -238.5k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -165.4k |
| MORGAN STANLEY | Reduced | -164.5k |
Biggest calls
| Ikarian Capital, LLC | Added | $2.1m141.0k shares |
| SIMPLEX TRADING, LLC | Added | $671.0k45.1k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Added | $612.0k41.1k shares |
| CITADEL ADVISORS LLC | Added | $585.2k39.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $552.4k37.1k shares |
| CITIGROUP INC | New | $445.2k29.9k shares |
| GROUP ONE TRADING LLC | Reduced | $119.1k8.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.3m85.2k shares |
| CITIGROUP INC | New | $445.2k29.9k shares |
| CITADEL ADVISORS LLC | Reduced | $336.5k22.6k shares |
| GROUP ONE TRADING LLC | Added | $17.9k1.2k shares |
| SIMPLEX TRADING, LLC | Reduced | $14.0k1.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
GILEAD SCIENCES, INC.
13D · may seek influence
-0.9 pts · filed 2026-08-07
Stated purposeOn May 27, 2020, Gilead and the Issuer entered into an Option, License and Collaboration Agreement (the "Collaboration Agreement") pursuant to with Gilead obtained an exclusive option to acquire an exclusive license to all of the Issuer's current and future clinical programs during the 10-year collaboration term and, for those programs that enter clinical development prior to the end of the collaboration term, for up to an additional three years thereafter. In addition to the Collaboration Agreement, Gilead and the Issuer entered into a Common Stock Purchase Agreement (the "Purchase Agreement"), which was amended and restated on January 31, 2021 to account for the Second Purchase (the "Amended and Restated Purchase Agreement"), on June 27, 2023 to account for the Third Purchase (the "Seco… Full filing |
24.7% |
| BlackRock, Inc. 13G · institution +1.0 pts · filed 2026-01-08 | 10.4% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26), Point72 Asset Management, L.P. (4.1%, 2025-11-14)
Insider purchases and sales in Q4 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2023 | 0 | — | 1 | $191.4k | — |
| Q2 2023 | 0 | — | 2 | $562.0k | $562.0k |
| Q3 2023 | 0 | — | 2 | $1.4m | $1.4m |
| Q4 2023 | 0 | — | 2 | $386.4k | $386.4k |
| Q1 2024 | 0 | — | 3 | $2.3m | $2.3m |
| Q2 2024 | 0 | — | 0 | — | — |
| Q3 2024 | 0 | — | 1 | $20.3k | $20.3k |
| Q4 2024 | 0 | — | 2 | $57.0k | $57.0k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-12-31 | Goeltz II Robert C. Chief Financial Officer | Sold plan | $53.9k3.6k shares |
| 2024-12-02 | Azoy Alexander Chief Accounting Officer | Sold plan | $3.1k201 shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2024
| Manager | Shares | Change |
|---|---|---|
| GILEAD SCIENCES, INC. 28.86% of their portfolio | 30.1m $447.6m | First filing |
| BlackRock, Inc. 0.00% of their portfolio | 9.7m $144.3m | Reduced -38.1k |
| VANGUARD GROUP INC 0.00% of their portfolio | 5.4m $80.2m | Reduced -79.5k |
| FMR LLC 0.00% of their portfolio | 4.1m $60.3m | Reduced -415.0k |
| Woodline Partners LP 0.36% of their portfolio | 3.5m $52.5m | Added +45.5k |
| STATE STREET CORP 0.00% of their portfolio | 3.0m $44.6m | Reduced -17.4k |
| Point72 Asset Management, L.P. 0.08% of their portfolio | 2.0m $29.7m | Reduced -440.8k |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 1.7m $25.3m | Added +178.4k |
| Siren, L.L.C. 1.06% of their portfolio | 1.6m $24.0m | Unchanged |
| Boxer Capital Management, LLC 2.03% of their portfolio | 1.6m $23.9m | First filing |
| AMERIPRISE FINANCIAL INC 0.01% of their portfolio | 1.5m $23.0m | Added +228.3k |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.06% of their portfolio | 1.5m $22.7m | Added +590.7k |
| Parkman Healthcare Partners LLC 2.53% of their portfolio | 1.3m $19.0m | Added +248.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.2m $18.0m | Reduced -12.6k |
| MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio | 924.4k $13.8m | Added +679.3k |
| Decheng Capital LLC 2.58% of their portfolio | 808.8k $12.0m | Reduced -61.0k |
| BRAIDWELL LP 0.35% of their portfolio | 802.1k $11.9m | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 579.6k $8.6m | Added +12.6k |
| MONTANOVA CAPITAL, LLC 0.32% of their portfolio | 576.2k $8.6m | Reduced -87.4k |
| MORGAN STANLEY 0.00% of their portfolio | 549.9k $8.2m | Reduced -164.5k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 532.1k $7.9m | Added +22.2k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.02% of their portfolio | 465.3k $6.9m | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 443.5k $6.6m | Reduced -259.9k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio | 443.0k $6.6m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 381.6k $5.7m | Added +30.3k |
| MACQUARIE GROUP LTD 0.01% of their portfolio | 379.1k $5.6m | Unchanged |
| Ikarian Capital, LLC 1.61% of their portfolio | 378.4k $5.6m | Reduced -365.6k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 360.6k $5.4m | Added +42.7k |
| READYSTATE ASSET MANAGEMENT LP 0.22% of their portfolio | 351.4k $5.2m | New |
| Granahan Investment Management, LLC 0.22% of their portfolio | 346.1k $5.2m | Reduced -11.7k |
| Trexquant Investment LP 0.05% of their portfolio | 300.5k $4.5m | Added +212.6k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 263.5k $3.9m | Added +7.9k |
| DAFNA Capital Management LLC 0.96% of their portfolio | 254.2k $3.8m | Reduced -2.5k |
| AXA S.A. 0.01% of their portfolio | 231.9k $3.5m | Reduced -364 |
| Cubist Systematic Strategies, LLC 0.05% of their portfolio | 225.2k $3.4m | Added +154.9k |
| NORDEA INVESTMENT MANAGEMENT AB 0.00% of their portfolio | 218.9k $3.2m | Added +5.2k |
| Invesco Ltd. 0.00% of their portfolio | 204.0k $3.0m | Added +35.9k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 202.5k $3.0m | Reduced -14.5k |
| ALGERT GLOBAL LLC 0.06% of their portfolio | 180.1k $2.7m | Added +67.3k |
| Hudson Bay Capital Management LP 0.02% of their portfolio | 170.0k $2.5m | Reduced -5.0k |
| DIADEMA PARTNERS LP 2.78% of their portfolio | 166.0k $2.5m | First filing |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 160.1k $2.4m | Added +19.2k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 159.3k $2.4m | Reduced -2.6k |
| PLATINUM INVESTMENT MANAGEMENT LTD 0.13% of their portfolio | 153.8k $2.3m | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 149.2k $2.2m | Added +2.2k |
| TWO SIGMA INVESTMENTS, LP 0.01% of their portfolio | 146.7k $2.2m | Added +11.0k |
| Public Sector Pension Investment Board 0.01% of their portfolio | 135.0k $2.0m | Added +20.6k |
| Schonfeld Strategic Advisors LLC 0.01% of their portfolio | 135.0k $2.0m | Reduced -538.8k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 131.9k $2.0m | Reduced -38.0k |
| UBS Group AG 0.00% of their portfolio | 131.1k $2.0m | Added +45.2k |
| PDT Partners, LLC 0.17% of their portfolio | 125.8k $1.9m | Added +38.1k |
| GILDER GAGNON HOWE & CO LLC 0.02% of their portfolio | 119.0k $1.8m | Reduced -7.3k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.05% of their portfolio | 114.5k $1.7m | Reduced -112.0k |
| BARCLAYS PLC 0.00% of their portfolio | 113.0k $1.7m | Reduced -5.7k |
| CITIGROUP INC 0.00% of their portfolio | 106.7k $1.6m | Added +40.7k |
| Swiss National Bank 0.00% of their portfolio | 98.3k $1.5m | Unchanged |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 97.8k $1.5m | Added +9.8k |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 90.5k $1.3m | Reduced -3.7k |
| Parallel Advisors, LLC 0.03% of their portfolio | 85.8k $1.3m | Unchanged |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 0.00% of their portfolio | 78.5k $1.2m | Reduced -2.3k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 77.7k $1.2m | Reduced -6.5k |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.03% of their portfolio | 76.6k $1.1m | Added +44.8k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 74.3k $1.1m | Added +932 |
| ALPS ADVISORS INC 0.01% of their portfolio | 74.0k $1.1m | Added +5.6k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 72.5k $1.1m | Reduced -1.2m |
| WINTON GROUP Ltd 0.07% of their portfolio | 72.3k $1.1m | Added +3.7k |
| GSA CAPITAL PARTNERS LLP 0.08% of their portfolio | 71.5k $1.1m | Reduced -115.9k |
| SECTORAL ASSET MANAGEMENT INC 0.69% of their portfolio | 69.6k $1.0m | Reduced -6.0k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 64.0k $953.6k | New |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 62.0k $923.4k | Reduced -7.9k |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 60.2k $896.0k | New |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 58.8k $875.5k | Added +15.5k |
| Balyasny Asset Management L.P. 0.00% of their portfolio | 58.2k $866.5k | Added +9.6k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 55.3k $823.5k | Reduced -600 |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 52.1k $775.0k | Unchanged |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 50.2k $747.7k | Added +16.0k |
| Persistent Asset Partners Ltd 0.55% of their portfolio | 50.2k $647.7k | First filing |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 47.3k $704.9k | Reduced -269 |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 46.8k $697.0k | Added +17.0k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 45.7k $680.7k | Reduced -2.8k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 43.4k $645.5k | Reduced -44.0k |
| TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio | 43.0k $639.8k | Reduced -2.7k |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 41.7k $621.0k | Reduced -627 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 38.6k $575.0k | Added +19.9k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 35.7k $531.0k | First filing |
| NORGES BANK 0.00% of their portfolio | 34.0k $506.9k | Reduced -43.1k |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 34.0k $506.4k | Added +833 |
| MetLife Investment Management, LLC 0.00% of their portfolio | 33.5k $499.2k | Added +2.5k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 33.2k $494.7k | Added +2.4k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 30.9k $461.0k | Reduced -6.3k |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 30.8k $458.0k | Added +29.5k |
| State of Alaska, Department of Revenue 0.01% of their portfolio | 30.6k $455.0k | Reduced -183 |
| DARK FOREST CAPITAL MANAGEMENT LP 0.07% of their portfolio | 30.2k $449.7k | Added +15.3k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 30.0k $446.0k | Added +19.5k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 29.6k $440.2k | Reduced -763 |
| Corebridge Financial, Inc. 0.00% of their portfolio | 28.9k $430.8k | Reduced -2.3k |
| SG Americas Securities, LLC 0.00% of their portfolio | 28.5k $424.0k | Reduced -1.6k |
| Amundi 0.00% of their portfolio | 27.0k $403.3k | Added +15.6k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 26.2k $389.4k | Added +10.2k |
| Louisiana State Employees Retirement System 0.01% of their portfolio | 26.1k $388.6k | Unchanged |