ARCUS BIOSCIENCES INC RCUS
COM · Common Stock · CUSIP 03969F109
Biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersHayward, CA
- Founded2015
- Websitearcusbio.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($2.8m this quarter). Holder counts are more reliable. Shares outstanding: 72.4m as of 2022-10-28, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $20.68. Options: 10 managers hold calls ($6.6m notional), 10 hold puts ($14.7m).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 185 |
| Q4 2022 | 201 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $4.9m | $5.5m | 1.12 |
| Q4 2022 | $6.6m | $14.7m | 2.23 |
Biggest buyers
| Woodline Partners LP | New | +1.2m |
| FRED ALGER MANAGEMENT, LLC | New | +651.5k |
| CITADEL ADVISORS LLC | Added | +616.7k |
| PRICE T ROWE ASSOCIATES INC /MD/ | Added | +481.8k |
| BlackRock Inc. | Added | +460.8k |
| Point72 Asset Management, L.P. | Added | +367.5k |
| DIMENSIONAL FUND ADVISORS LP | Added | +314.1k |
| NORDEA INVESTMENT MANAGEMENT AB | New | +265.5k |
| EVENTIDE ASSET MANAGEMENT, LLC | New | +240.0k |
| MORGAN STANLEY | Added | +193.3k |
Biggest sellers
| PFM Health Sciences, LP | Reduced | -679.9k |
| PERCEPTIVE ADVISORS LLC | Sold out | -666.5k |
| Finepoint Capital LP | Sold out | -646.6k |
| STATE STREET CORP | Reduced | -597.8k |
| BVF INC/IL | Reduced | -413.5k |
| ORBIMED ADVISORS LLC | Sold out | -303.0k |
| PICTET ASSET MANAGEMENT SA | Reduced | -225.5k |
| Octagon Capital Advisors LP | Reduced | -185.6k |
| ALLIANCEBERNSTEIN L.P. | Reduced | -151.5k |
| DEUTSCHE BANK AG\ | Reduced | -149.4k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.7m130.1k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $2.3m110.0k shares |
| CITIGROUP INC | Added | $413.6k20.0k shares |
| PEAK6 Investments LLC | New | $374.3k18.1k shares |
| CITADEL ADVISORS LLC | New | $339.2k16.4k shares |
| GROUP ONE TRADING LLC | Added | $250.2k12.1k shares |
| SG3 Management, LLC | Not comparable | $171.6k8.3k shares |
| Caption Management, LLC | New | $49.6k2.4k shares |
| SIMPLEX TRADING, LLC | Added | $49.0k2.4k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| Ikarian Capital, LLC | New | $5.9m283.1k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $3.7m179.6k shares |
| CITADEL ADVISORS LLC | Added | $1.4m66.6k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | New | $1.2m56.4k shares |
| MILLENNIUM MANAGEMENT LLC | New | $844.0k40.8k shares |
| GROUP ONE TRADING LLC | New | $837.5k40.5k shares |
| CITIGROUP INC | Added | $413.6k20.0k shares |
| SIMPLEX TRADING, LLC | Added | $322.0k15.6k shares |
| SG3 Management, LLC | Not comparable | $186.1k9.0k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
GILEAD SCIENCES, INC.
13D · may seek influence
-0.9 pts · filed 2026-08-07
Stated purposeOn May 27, 2020, Gilead and the Issuer entered into an Option, License and Collaboration Agreement (the "Collaboration Agreement") pursuant to with Gilead obtained an exclusive option to acquire an exclusive license to all of the Issuer's current and future clinical programs during the 10-year collaboration term and, for those programs that enter clinical development prior to the end of the collaboration term, for up to an additional three years thereafter. In addition to the Collaboration Agreement, Gilead and the Issuer entered into a Common Stock Purchase Agreement (the "Purchase Agreement"), which was amended and restated on January 31, 2021 to account for the Second Purchase (the "Amended and Restated Purchase Agreement"), on June 27, 2023 to account for the Third Purchase (the "Seco… Full filing |
24.7% |
| BlackRock, Inc. 13G · institution +1.0 pts · filed 2026-01-08 | 10.4% |
Fell to 5% or below in the last year: VANGUARD GROUP INC (0.0%, 2026-03-26), Point72 Asset Management, L.P. (4.1%, 2025-11-14)
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 5 | $2.3m | — |
| Q1 2022 | 0 | — | 1 | $304.1k | — |
| Q2 2022 | 0 | — | 4 | $629.3k | — |
| Q3 2022 | 0 | — | 1 | $333.2k | — |
| Q4 2022 | 0 | — | 5 | $1.2m | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-12-16 | Jarrett Jennifer Chief Operating Officer, director | Sold | $506.8k16.5k shares |
| 2022-12-16 | ROSEN TERRY J Chief Executive Officer, director | Sold | $401.1k13.0k shares |
| 2022-12-16 | Jaen Juan C. President, director | Sold | $136.4k4.4k shares |
| 2022-12-16 | Tang Carolyn C. General Counsel | Sold | $77.6k2.5k shares |
| 2022-12-16 | Goeltz II Robert C. Chief Financial Officer | Sold | $75.4k2.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| BlackRock Inc. 0.01% of their portfolio | 9.4m $194.2m | Added +460.8k |
| VANGUARD GROUP INC 0.00% of their portfolio | 4.4m $90.4m | Reduced -84.0k |
| STATE STREET CORP 0.00% of their portfolio | 3.5m $73.3m | Reduced -597.8k |
| FMR LLC 0.01% of their portfolio | 3.3m $68.6m | Reduced -39.4k |
| PFM Health Sciences, LP 2.36% of their portfolio | 2.7m $55.9m | Reduced -679.9k |
| Octagon Capital Advisors LP 7.99% of their portfolio | 2.5m $51.3m | Reduced -185.6k |
| BVF INC/IL 2.01% of their portfolio | 2.3m $47.6m | Reduced -413.5k |
| Invus Financial Advisors, LLC 17.74% of their portfolio | 1.6m $33.3m | Unchanged |
| Boxer Capital, LLC 1.56% of their portfolio | 1.4m $29.6m | Unchanged |
| PICTET ASSET MANAGEMENT SA 0.04% of their portfolio | 1.3m $26.1m | Reduced -225.5k |
| Woodline Partners LP 0.34% of their portfolio | 1.2m $24.8m | New |
| DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio | 994.2k $20.6m | Added +314.1k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 946.5k $19.6m | Added +35.1k |
| ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio | 885.1k $18.3m | Reduced -151.5k |
| Decheng Capital Management III (Cayman), LLC 6.73% of their portfolio | 869.8k $18.0m | Unchanged |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.06% of their portfolio | 765.5k $15.8m | Added +143.0k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 762.4k $15.8m | Reduced -101.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 710.6k $14.7m | Added +17.6k |
| FRED ALGER MANAGEMENT, LLC 0.07% of their portfolio | 651.5k $13.5m | New |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 643.2k $13.3m | Added +616.7k |
| MORGAN STANLEY 0.00% of their portfolio | 546.3k $11.3m | Added +193.3k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 514.9k $10.6m | Added +11.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 505.7k $10.5m | Added +481.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 488.5k $10.1m | Added +17.8k |
| Point72 Asset Management, L.P. 0.03% of their portfolio | 425.3k $8.8m | Added +367.5k |
| Granahan Investment Management, LLC 0.26% of their portfolio | 410.5k $8.5m | Added +67.1k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 401.8k $8.3m | Reduced -45.0k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 388.7k $8.0m | Added +9.6k |
| MACQUARIE GROUP LTD 0.01% of their portfolio | 379.1k $7.8m | Reduced -758 |
| PRINCIPAL FINANCIAL GROUP INC 0.01% of their portfolio | 329.0k $6.8m | Reduced -12.2k |
| Sofinnova Investments, Inc. 0.40% of their portfolio | 314.8k $6.5m | Reduced -66.5k |
| Invesco Ltd. 0.00% of their portfolio | 272.3k $5.6m | Added +5.8k |
| NORDEA INVESTMENT MANAGEMENT AB 0.01% of their portfolio | 265.5k $5.5m | New |
| EVENTIDE ASSET MANAGEMENT, LLC 0.10% of their portfolio | 240.0k $5.0m | New |
| GILDER GAGNON HOWE & CO LLC 0.09% of their portfolio | 238.8k $4.9m | Reduced -2.4k |
| SECTORAL ASSET MANAGEMENT INC 0.95% of their portfolio | 238.5k $4.9m | Added +11.4k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 204.1k $4.2m | Reduced -5.0k |
| PANAGORA ASSET MANAGEMENT INC 0.03% of their portfolio | 197.6k $4.1m | Added +13.5k |
| Rafferty Asset Management, LLC 0.03% of their portfolio | 195.0k $4.0m | Reduced -33.6k |
| TWO SIGMA ADVISERS, LP 0.01% of their portfolio | 172.3k $3.6m | Reduced -2.5k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 163.0k $3.4m | Added +4.7k |
| PLATINUM INVESTMENT MANAGEMENT LTD 0.12% of their portfolio | 154.9k $3.2m | Added +93.1k |
| Schonfeld Strategic Advisors LLC 0.03% of their portfolio | 154.3k $3.2m | Added +23.7k |
| Legal & General Group Plc 0.00% of their portfolio | 150.6k $3.1m | Added +2.0k |
| TANG CAPITAL MANAGEMENT LLC 0.44% of their portfolio | 147.9k $3.1m | Reduced -52.1k |
| AXA S.A. 0.01% of their portfolio | 146.5k $3.0m | Reduced -148.2k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 144.6k $3.0m | Added +132.1k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 144.6k $3.0m | Added +2.2k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 142.3k $2.9m | Reduced -24.4k |
| DAFNA Capital Management LLC 0.83% of their portfolio | 142.2k $2.9m | Reduced -36.5k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 139.0k $2.9m | Reduced -10.5k |
| Ikarian Capital, LLC 1.18% of their portfolio | 138.0k $2.9m | New |
| PUTNAM INVESTMENTS LLC 0.00% of their portfolio | 131.6k $2.7m | Reduced -7.0k |
| TWINBEECH CAPITAL LP 0.05% of their portfolio | 129.6k $2.7m | New |
| CITIGROUP INC 0.00% of their portfolio | 126.7k $2.6m | Reduced -108.0k |
| BARCLAYS PLC 0.00% of their portfolio | 126.0k $2.6m | First filing |
| HRT FINANCIAL LP 0.04% of their portfolio | 124.8k $2.6m | New |
| AQR CAPITAL MANAGEMENT LLC 0.01% of their portfolio | 121.0k $2.5m | Added +856 |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 116.1k $2.4m | Reduced -1.4k |
| Assenagon Asset Management S.A. 0.01% of their portfolio | 115.7k $2.4m | New |
| Cubist Systematic Strategies, LLC 0.02% of their portfolio | 108.9k $2.3m | Added +36.4k |
| Swiss National Bank 0.00% of their portfolio | 104.5k $2.2m | Added +2.5k |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 99.7k $2.1m | Added +14.9k |
| Public Sector Pension Investment Board 0.02% of their portfolio | 94.8k $2.0m | Reduced -388 |
| Parkman Healthcare Partners LLC 0.48% of their portfolio | 87.5k $1.8m | Reduced -50.4k |
| Parallel Advisors, LLC 0.08% of their portfolio | 85.2k $1.8m | Added +295 |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 83.8k $1.7m | Added +800 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 82.0k $1.7m | Reduced -22.0k |
| DUALITY ADVISERS, LP 0.19% of their portfolio | 81.4k $1.7m | Added +56.6k |
| HighVista Strategies LLC 0.88% of their portfolio | 71.7k $1.5m | Unchanged |
| Bellevue Group AG 0.02% of their portfolio | 65.9k $1.4m | Reduced -17.6k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 65.8k $1.4m | Reduced -245 |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 65.7k $1.4m | Added +48.0k |
| TD Asset Management Inc 0.00% of their portfolio | 62.3k $1.3m | New |
| UBS Group AG 0.00% of their portfolio | 59.7k $1.2m | Added +20.1k |
| Monarch Partners Asset Management LLC 0.36% of their portfolio | 58.8k $1.2m | Added +417 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 58.1k $1.2m | Added +809 |
| Engineers Gate Manager LP 0.07% of their portfolio | 57.7k $1.2m | Added +49.2k |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS 0.01% of their portfolio | 55.8k $1.2m | Added +8.5k |
| Kiwi Wealth Investments Limited Partnership 0.08% of their portfolio | 55.4k $1.1m | New |
| Man Group plc 0.00% of their portfolio | 54.1k $1.1m | New |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 53.5k $1.1m | Reduced -231 |
| CANADA LIFE ASSURANCE Co 0.00% of their portfolio | 53.0k $1.1m | Reduced -3.8k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 52.8k $1.1m | Reduced -149.4k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 52.3k $1.1m | Added +3.3k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 50.3k $1.0m | Added +29.5k |
| Hudson Bay Capital Management LP 0.01% of their portfolio | 50.0k $1.0m | Added +25.0k |
| VIRGINIA RETIREMENT SYSTEMS ET Al 0.01% of their portfolio | 49.6k $1.0m | Added +9.4k |
| ALPS ADVISORS INC 0.01% of their portfolio | 48.8k $1.0m | Added +9.4k |
| Robeco Institutional Asset Management B.V. 0.00% of their portfolio | 46.0k $951.1k | Added +15.9k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 44.5k $920.8k | Reduced -92.4k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 43.4k $897.5k | Reduced -332 |
| PDT Partners, LLC 0.13% of their portfolio | 38.6k $798.8k | Reduced -19.9k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 37.5k $775.1k | Reduced -1.5k |
| State of Alaska, Department of Revenue 0.01% of their portfolio | 36.3k $750.0k | Added +332 |
| YOUSIF CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 35.4k $731.3k | Reduced -8.8k |
| Ergoteles LLC 0.03% of their portfolio | 35.3k $730.1k | New |
| State of Tennessee, Department of Treasury 0.00% of their portfolio | 35.2k $728.0k | Added +1.9k |
| TEXAS PERMANENT SCHOOL FUND CORP 0.01% of their portfolio | 35.0k $725.0k | Reduced -2.3k |
| ExodusPoint Capital Management, LP 0.01% of their portfolio | 34.0k $703.0k | Added +11.1k |